Ceylan, Yusuf; Korkmaz, Nesrin; Kaçan, Fatma N.; Aydin, Ali; Korkmaz, Şengül A.; Yildirim, Ebru Ş.

Copper oxide nanoparticles (CuO NPs) were synthesized using a green approach with Vitis vinifera L. extract, a plant rich in secondary metabolites that act as natural reducing agents. The obtained CuO NPs were characterized by XRD, EDX, and STEM analyses. FT-IR analysis revealed the presence of functional groups originating from plant biomolecules and confirmed the formation of Cu–O bonds, indicating the successful synthesis and stabilization of CuO NPs. XRD confirmed distinctive CuO diffraction peaks at 32.38°, 35.35°, 38.61°, 40.75°, 48.79°, 51.90°, 57.66°, 61.38°, 65.94°, and 75.12°. STEM imaging showed predominantly spherical, well-dispersed nanoparticles with an average size of 23–38 nm. Antibacterial analysis revealed a minimum inhibitory concentration (MIC) of 4 µg mL−1 against Escherichia coli ATCC 25922. In anticancer assays, the CuO NPs demonstrated notable cytotoxicity at both low concentrations and even at levels below the control group in A549, Calu-1, and Saos-2 cancer cell lines, highlighting their strong biomedical potential.

AtıfScopus1·WoS1·OpenAlex1

İncele

Unal, Ilkay; Egri, Sinan

This study describes an eco-friendly procedure to synthesize silver nanoparticles (AgNPs) using fresh and dried stem extract of Rheum ribes. AgNPs formation was confirmed using UV-vis spectrometry. The effects of parameters such as temperature, reaction time, pH, AgNO3 concentration, and plant extract/AgNO3 ratio on NP formation were evaluated. Morphology and structural features of the particles were characterized using SEM, TEM, XRD, and FTIR. The average size, polydispersity index, and zeta potential were determined using DLS. After characterization, among the two AgNP samples, selected one; AgNP sample synthesized by dried Rheum ribes stem extracts (d-AgNPs), which exhibited narrow size distribution and high surface plasmon resonance in the range of 435-445 nm for toxicity assessment. The cytotoxic effect of d-AgNPs on HUVECs cells was evaluated with MTT analysis. Accumulation measurements were made in three periods as 24, 48, and 72 h and elimination values were examined at +24 h using ICP-MS analysis

AtıfWoS6·OpenAlex6

İncele

Ünal, İlkay; Ertürk Gürkan, Selin

Evaluation of the effects of nanomaterials in various habitats and living groups is increasing with in vitro and in vivo studies. This study aims to describe a biological procedure to synthesize silver nanoparticles using an extract of Marrubium astracanicum and to determine the aquatic environment’s oxidative stress on Artemia salina. Silver nanoparticle formation was visually observed with color change. Its structural properties, such as size, shape, morphology, and stability, were characterized by UV-Vis spectrophotometer, TEM, SEM, XRD, and DLS analyses. TEM image showed that the synthesized AgNPs have a size of between 20 and 50 nm. The effects of biosynthesized silver nanoparticles at different concentrations (control,0.2, 1, 5, 10, 25, and 50 mg/mL) and exposure times (24, 48 and 72 h) on total glutathione (GSH) and lipid peroxidation levels (MDA) were investigated on the Artemia salina organism, which is one of the most common saltwater organisms frequently used in ecotoxicity tests.

AtıfScopus4·WoS2·OpenAlex3

İncele

Aslan Korkmaz, Şengül

The green synthesis method used to synthesize Co3O4-NPs has attracted numerous advantages due to its low cost, less time and energy consume, no need of special instruments for experimental and more eco-friendly with environment. In this study, the Co3O4-NPs were synthesized by green synthesis method to overcome the toxicity of chemical synthesis. And Allium tuncelianum plant which is an endemic species in Tunceli was used as a reducing agent and Co(NO3)2.6H2O as a source of cobalt. The synthesized Co3O4-NPs were characterized by using FTIR, XRD, SEM and HR-TEM techniques. The XRD pattern was shown that the Co-NPs were face-centered cubic (fcc) of crystalline nature and the average crystallite size was found nearly 23 nm with a value of COD(R^2): 0.982. The Co3O4-NPs generally had a spherical shape in the SEM images taken at 200 nm. The Co3O4-NPs showed low IC50 value against HeLa cells compare with RPE normal cells.

AtıfScopus7·WoS10·OpenAlex8

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