Turan, Nevin; Adigüzel, Ragip; Buldurun, Kenan; Bursal, Ercan

The novel mixed ligand-metal complexes with a general formula [M(Sac)(2)(H2O)(2)L-2]center dot nH(2)O) [M = Mn(II), Co(II), Ni(II), Cu(II) and Cd(II), L=5-Methly-4-(4-nitrophenylazo)-2H-pyrazole-3-ylamine (mnppa)] have been synthesized and characterized by elemental analyses, IR, UV-VIS, magnetic susceptibility mass spectra and thermogravimetry-differential thermal analysis (TGA-DTA). Each metal (II) ion is octahedral coordinated by two sac, two mnppa and two aqua ligands. The antioxidant properties of mixed ligand-metal complexes were determined by different in vitro methods such as ABTS, DPPH, FRAP and CUPRAC assays. The results of metal complexes were compared with standard antioxidant compounds.

AtıfWoS30·OpenAlex30

İncele

Turan, Nevin; Savci, Ahmet; Buldurun, Kenan; Alan, Yusuf; Adigüzel, Ragip

Fe(II) and Zn(II) complex series have been synthesized from Schiff base ligands derived from furan-2-carbaldehyde and thiophene-2-carbaldehyde. Elemental, infrared, ultra-violet- visible, NMR and thermal analysis, also mass spectroscopy and magnetic susceptibility measurements were performed to explain the structures of these synthesized ligands and their metal complexes. The formulas based on analytical, spectral, and magnetic studies, the complexes can be demonstrated as [M(L-1)(2)](H2O)(n), [M(L-2)(2)](H2O)(n), where M = Zn(II) and Fe(II). An octahedral geometry was suggested for the Zn(II) and Fe(II) complexes. The antioxidant, antiradical and antimicrobial properties of the Zn(II) and Fe(II) complexes were investigated using different in vitro assays. Some of the complexes showed reasonable amount of antioxidant and antimicrobial activity.

AtıfWoS19·OpenAlex19

İncele

Turan, Nevin; Körkoca, Hanifi; Adigüzel, Ragip; Çolak, Naki; Buldurun, Kenan

Some new Zn(II) and Cu(II) complexes [Cu(L-1)(OAc)(2)].H2O, [Cu(L-1)(NO3)H2O].NO3.3.5H(2)O, [Zn(L-1)(NO3)(2)].4.5H(2)O, [Zn(L-1)(OAc)(2)(H2O)(2)].3H(2)O, [Cu-2(L-2)(OAc)(4)].2H(2)O.2DMF, [Cu(L-2)(2)].2NO(3).1.5DMF.H2O, [Zn(L-2)(2)(NO3)(2)].DMF and [Zn-2(L-2)(OAc)(4)(H2O)(4)].5H(2)O; L-1 = 2-[2-(2-methoxyphenyl)hydrazono]cyclohexane-1,3-dione and L-2 = 2-[2-(3-nitrophenyl)hydrazono]cyclohexane-1,3-dione were synthesized and characterized by IR, H-1-NMR,C-13-NMR and ultraviolet (UV-Vis.) spectroscopy, elemental analysis, magnetic susceptibility, mass spectrometry and thermogravimetry-differential thermal analysis (TGA-DTA). The synthesized ligands and their complexes were tested for antibacterial activity against Escherichia coli ATCC 25922, Enterococcus faecalis ATCC 29212, Staphylococcus aureus ATCC 25923, and Salmonella typhimurium CCM 583. Some of complexes showed medium-level antibacterial activity against the test bacteria compared with ampicillin.

AtıfWoS20·OpenAlex18

İncele

Turan, Nevin; Gündüz, Bayram; Körkoca, Hanifi; Adigüzel, Ragip; Çolak, Naki; Buldurun, Kenan

A new chelating ligand, 5,5-dimethyl-2-(2-(3-nitrophenyl)hydrazono)cyclohexane-1,3-dione (L), and four transition metal complexes were synthesized. The ligand and its complexes were characterized by IR, H-1 and C-13-NMR spectra, elemental analyses, magnetic susceptibility, mass spectra, UV-Vis. and thermogravimetry-differential thermal analysis (TGA-DTA). The metal complexes showed different geometric structures. Antibacterial tests of the ligand and complexes were also done. The Zn(II) complexes showed antibacterial activity against Staphylococcus aureus ATCC-25923 at middle level. The optical properties of the ligand and its complexes were extensively investigated by optical measurements. The average transmittance value of the ligand was the highest value, while the average transmittance value of the [CuL2(NO3)(2)]center dot 6H(2)O complex was the lowest value. The optical band gap of the ligand, [(Zn)(2)L(OH)(4)]center dot 2DMF, [ZnL(NO3)(2)(H2O)(2)]center dot 5H(2)O, [CuL2(OAc)]center dot OAc center dot 3.5H(2)O and [CuL2(NO3)(2)]center dot 6H(2)O complexes were calculated and 3.121 eV, 2.180 eV, 1.551 eV, 2.489 eV and 1.556 eV values were found, respectively. The complexes decreased the optical band gap of the ligand. The optical band gap value of the [ZnL(NO3)(2)(H2O)(2)]center dot 5H(2)O complex is the lowest value. The optical band gap value of the ligand is the highest value. The complexes decrease the angle of incidence of the ligand, while complexes increase the angle of refraction of the ligand. The electric susceptibility of the ligand decreases with its complexes.

AtıfWoS28

İncele

Adigüzel, Ragip; Tascioglu, Senay

Complexation reactions between water-soluble and -insoluble reactants were shown to occur in aqueous media in the presence of normal or reverse surfactant micelles, in significantly higher yields at lower temperatures compared to those achieved in neat organic solvents. The highest yield enhancement in the complexation of novel water-insoluble bis(2-amino-1,3,4-thiadiazolyl)methane and 1,4-bis(2-amino-1,3,4-thiadiazolyl)benzene ligands with Cu(II) ions was achieved in the sodium bis(2-ethylhexyl)sulfosuccinate (AOT)-heptane-water reverse micellar system at the hydration ratio of 15. The results revealed that AOT normal micelles cause a change in the reaction mechanism together with the enhancement of the complex formation. The observed micellar effects were rationalized on basis of the properties of bulk solvents, surfactants and ligands, considering the solvation and hydration ratios of reverse micelles. The results have proved the dependence of complex yield on the amount and accordingly also on the properties of water in the micellar core, indicating that the yield can be maximized by the optimization of the hydration ratio.

AtıfWoS4·OpenAlex5

İncele