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- MakaleYalnız künye2018Scopus SJRQ3Investigation of biochemical response in rainbow trout (Oncorhynchus mykiss, Walbaum, 1792) exposed to remazol brillant blue R textile dye
Yildirim, N.C.; Dogan, L.
The dyes used in textile industry production are toxic substances and most of them have polymer structures. These dyes pollute the aquatic environment via various stages such as printing and dyeing, and may cause molecular, cellular, biochemical and physiological disorders. The aim of the present study was to evaluate effect of a highly toxic azo dye, Remazol Brillant Blue (RBBR) on the biochemical responses of rainbow trout, Oncorhynchus mykiss. The fishes were exposed to 0.5, 1 and 2 mg/l of RBBR for 24 and 48 h. The glutathione S-transferase (GST), cytochrome P-450 (CYP1A1) and lactate dehydrogenase (LDH) enzyme activities of these groups were measured. Present dye altered the activities of all these enzymes in the selected tissue of the experimental fish in a dose-dependent manner. According to the results of this study, after dye exposure, the alteration of selected enzymes indicated deterioration in antioxidant defense system, aerobic respiration processes and biotransformation mechanism induced by the tested dye. It was also shown that GST, CYP1A1 and LDH enzymes may be useful as biomarkers in determining the toxic effects in O. mykiss exposed to the RBBR textile dye.
AtıfScopus2
İncele - MakaleYalnız künye2017Scopus SJRQ3Biochemical impacts of the textile dyes Remazol Brillant Blue R and Congo Red on the crayfish Astacus leptodactylus (Decapoda, Astacidae)
Aksu, Onder; Yildirim, Nuran Cikcikoglu; Danabas, Durali; Yildirim, Numan
In this study, we determined the effects of the textile dyes Remazol Brillant Blue R (RBBR) and Congo Red (CR) on the enzymatic activities of Glutathione S-Transferase (GST), cytochrome P450 (CYP1A1) and Lactate dehydrogenase (LDH), in hepatopancreas of Astacus leptodactylus. The crayfishes were exposed to 0.5, 1.0, and 2.0 mg/l of RBBR or CR, for 24 and 48 h. The recorded GST activity clearly increased after 24 or 48 h exposure to CR, compared to a control group (p<0.05), but the changes of GST activity depending on time and dose were not statistically significant in the RRBR group (p<0.05). The activity of CYP1A1 generally decreased, but LDH activity increased in the groups exposed to different doses of CR and RBBR, when compared to their control groups. Detoxification enzymes (as GST, and CYP1A1) and metabolic enzymes (as LDH) can be proven to make useful markers for further evaluating the physiological effects of CR and RBBR on crayfish.
AtıfScopus21WoS19OpenAlex23
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