Sürdürülebilir Kalkınma Amaçları

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• MakaleAçık Erişim2024Scopus SJRQ1/r/munzur/1924
  Determination of oxidative stress responses caused by aluminum oxide (γ-Al2O3 and α-Al2O3) nanoparticles in Gammarus pulex

  Serdar, Osman; Aydin, Ayşe Nur; Çimen, Isıl Canan Çiçek

  The rapid growth in the use of aluminum oxide nanoparticles (Al2O3 NPs) in various fields such as medicine, pharmacy, cosmetics industries and engineering, and the fact that these NPs and their wastes mix with the aquatic environment and damage the aquatic ecosystem, affect the organisms in the water, enter the food chain and reach humans is a major problem is cause for concern. The aim of this study is to investigate the oxidative stress caused by two separate forms of aluminum oxide, γ-Al2O3 and α-Al2O3, in Gammarus pulex, which is a good indicator species, with biochemical parameters. For this purpose, G. pulex was exposed to different concentrations (0, 10, 20, 40 ppm) of γ-Al2O3 and α-Al2O3 separately. The experiments were carried out for 24 and 96 h by creating 3 repeated experimental groups consisting of 4 groups. For biomarker analysis, superoxide dismutase (SOD), catalase (CAT) activities and glutathione (GSH) and thiobarbituric acid (TBARS) levels were performed using an ELISA kit. As a result of the in experimental study, it was observed that both nanoparticles affected oxidative stress and antioxidant parameters after 96 h compared to the control group. Increases in SOD activity were observed, γ-Al2O3 caused a decrease in CAT activity at 24 h, and α- Al2O3 caused increases in CAT activity at 96 h. Decreases in GSH levels and increases in TBARS levels have been observed.

  AtıfScopus14·OpenAlex14

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• MakaleAçık Erişim2024Scopus SJRQ1/r/munzur/1922
  Assessment of toxicity and oxidative stress induced by rare earth oxide nanoparticles in brine shrimp (Artemia salina)

  Unal, Ilkay; Erturk Gurkan, Selin; Aydogdu, Burcu

  This study meticulously explored the oxidative stress effects induced by lanthanum (III) oxide (La2O3), erbium (III) oxide (Er2O3), and yttrium (III) oxide (Y2O3) nanoparticles on Artemia salina, with the objective of evaluating the environmental toxicity of rare earth oxide nanoparticles. The characterization of the nanoparticles was conducted using a suite of advanced techniques, including X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), dynamic light scattering (DLS), and zeta potential analysis. Artemia salina, a widely recognized model organism in ecotoxicological research, was exposed to these nanoparticles under meticulously controlled laboratory conditions. The investigation focused on quantifying oxidative stress markers, such as reduced glutathione (GSH), malondialdehyde (MDA), and antioxidant enzymes including catalase (CAT), superoxide dismutase (SOD), and glutathione-S-transferase (GST). The findings revealed significant alterations in these biomarkers, indicating nanoparticle-induced oxidative stress, which varied according to the type of nanoparticle and the duration of exposure.

  AtıfScopus9·OpenAlex9

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• MakaleAçık Erişim2016Scopus SJRQ1/r/munzur/4507
  A comparative toxicity study between small and large size zinc oxide nanoparticles in tilapia (Oreochromis niloticus): Organ pathologies, osmoregulatory responses and immunological parameters

  Kaya, Hasan; Aydin, Fatih; Gürkan, Mert; Yilmaz, Sevdan; Ates, Mehmet; Demir, Veysel; Arslan, Zikri

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  AtıfOpenAlex121

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