Sürdürülebilir Kalkınma Amaçları

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• MakaleAçık Erişim2019Scopus SJRQ3/r/munzur/3596
  Bioactivity-guided isolation of anti-inflammatory principles from Cistus parviflorus Lam.

  Gürbüz, Perihan; Doğan, Şengül Dilem; Çelik, Gizem Nur; Bekci, Hatice; Cumaoğlu, Ahmet; Gündüz, Miyase Gözde; Paksoy, Mehmet Yavuz

  Bioactivity-guided fractionation and purification of Cistus parviflorus led to the isolation of two flavan-3-ol derivatives; gallocatechin (1) and epigallocatechin (2) and two flavonoid glycosides; avicularin (3) and trans-tiliroside (4). The structures of the compounds were elucidated on the basis of NMR and ESIMS data. All compounds were isolated from C. parviflorus for the first time. Compounds 2 and exhibited antiinflammatory activity through decreasing the NOS2 and COX2 levels on LPS+IFN-γ treated RAW 264.7 cells. Molecular docking studies of avicularin, the most potent compound, were carried out in the active sites of NOS2 and COX2 to predict the most plausible binding modes and support the experimental data.

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  AtıfScopus7·OpenAlex8·TR Dizin2

  İncele
• MakaleAçık Erişim2018Scopus SJRQ2/r/munzur/4523
  Chemical Composition of the Essential Oil and Antimicrobial Activity of Scaligeria DC. Taxa and Implications for Taxonomy

  Baldemir, Ayse; Demirci, Betul; Paksoy, Mehmet Yavuz; Ilgün, Selen; Kosar, Mberra; Baser, Kemal Husnu Can; Demirci, Fatih

  AtıfOpenAlex5

  İncele
• MakaleYalnız künye2017Scopus SJRQ2/r/munzur/4515
  Essential Oil Composition of Three Centaurea Species from Turkey: Centaurea aggregata Fisch & Mey. ex. DC. subsp aggregata, C. balsamita Lam. and C. behen L.

  Erdogan, Tugce; Sümer, Burcu; Özçinar, Ozge; Çakilcioglu, Ugur; Demirci, Betul; Baser, Kemal Husnu Can; Kivçak, Bijen

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