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- Derleme MakaleAçık Erişim2025Scopus SJRQ1Automated Detection of Neurological and Mental Health Disorders Using EEG Signals and Artificial Intelligence: A Systematic Review
Uyanik, Hakan; Sengur, Abdulkadir; Salvi, Massimo; Tan, Ru-San; Tan, Jen Hong; Acharya, U. Rajendra
Mental and neurological disorders significantly impact global health. This systematic review examines the use of artificial intelligence (AI) techniques to automatically detect these conditions using electroencephalography (EEG) signals. Guided by Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA), we reviewed 74 carefully selected studies published between 2013 and August 2024 that used machine learning (ML), deep learning (DL), or both of these two methods to detect neurological and mental health disorders automatically using EEG signals. The most common and most prevalent neurological and mental health disorder types were sourced from major databases, including Scopus, Web of Science, Science Direct, PubMed, and IEEE Xplore. Epilepsy, depression, and Alzheimer's disease are the most studied conditions that meet our evaluation criteria, 32, 12, and 10 studies were identified on these topics, respectively. Conversely, the number of studies meeting our criteria regarding stress, schizophrenia, Parkinson's disease, and autism spectrum disorders was relatively more average: 6, 4, 3, and 3, respectively. The diseases that least met our evaluation conditions were one study each of seizure, stroke, anxiety diseases, and one study examining Alzheimer's disease and epilepsy together. Support Vector Machines (SVM) were most widely used in ML methods, while Convolutional Neural Networks (CNNs) dominated DL approaches. DL methods generally outperformed traditional ML, as they yielded higher performance using huge EEG data. We observed that the complex decision process during feature extraction from EEG signals in ML-based models significantly impacted results, while DL-based models handled this more efficiently. AI-based EEG analysis shows promise for automated detection of neurological and mental health conditions. Future research should focus on multi-disease studies, standardizing datasets, improving model interpretability, and developing clinical decision support systems to assist in the diagnosis and treatment of these disorders.
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İncele - MakaleAçık Erişim2023Scopus SJRQ1PatchResNet: Multiple Patch Division–Based Deep Feature Fusion Framework for Brain Tumor Classification Using MRI Images
Muezzinoglu, Taha; Baygin, Nursena; Tuncer, Ilknur; Barua, Prabal Datta; Baygin, Mehmet; Dogan, Sengul; Tuncer, Turker; Palmer, Elizabeth Emma; Cheong, Kang Hao; Acharya, U. Rajendra
Modern computer vision algorithms are based on convolutional neural networks (CNNs), and both end-to-end learning and transfer learning modes have been used with CNN for image classification. Thus, automated brain tumor classification models have been proposed by deploying CNNs to help medical professionals. Our primary objective is to increase the classification performance using CNN. Therefore, a patch-based deep feature engineering model has been proposed in this work. Nowadays, patch division techniques have been used to attain high classification performance, and variable-sized patches have achieved good results. In this work, we have used three types of patches of different sizes (32 × 32, 56 × 56, 112 × 112). Six feature vectors have been obtained using these patches and two layers of the pretrained ResNet50 (global average pooling and fully connected layers). In the feature selection phase, three selectors—neighborhood component analysis (NCA), Chi2, and ReliefF—have been used, and 18 final feature vectors have been obtained. By deploying k nearest neighbors (kNN), 18 results have been calculated. Iterative hard majority voting (IHMV) has been applied to compute the general classification accuracy of this framework. This model uses different patches, feature extractors (two layers of the ResNet50 have been utilized as feature extractors), and selectors, making this a framework that we have named PatchResNet. A public brain image dataset containing four classes (glioblastoma multiforme (GBM), meningioma, pituitary tumor, healthy) has been used to develop the proposed PatchResNet model. Our proposed PatchResNet attained 98.10% classification accuracy using the public brain tumor image dataset. The developed PatchResNet model obtained high classification accuracy and has the advantage of being a self-organized framework. Therefore, the proposed method can choose the best result validation prediction vectors and achieve high image classification performance.
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İncele - MakaleAçık Erişim2022Scopus SJRQ2Use of Differential Entropy for Automated Emotion Recognition in a Virtual Reality Environment with EEG Signals
Uyanık, Hakan; Ozcelik, Salih Taha A.; Duranay, Zeynep Bala; Sengur, Abdulkadir; Acharya, U. Rajendra
Emotion recognition is one of the most important issues in human–computer interaction (HCI), neuroscience, and psychology fields. It is generally accepted that emotion recognition with neural data such as electroencephalography (EEG) signals, functional magnetic resonance imaging (fMRI), and near-infrared spectroscopy (NIRS) is better than other emotion detection methods such as speech, mimics, body language, facial expressions, etc., in terms of reliability and accuracy. In particular, EEG signals are bioelectrical signals that are frequently used because of the many advantages they offer in the field of emotion recognition. This study proposes an improved approach for EEG-based emotion recognition on a publicly available newly published dataset, VREED. Differential entropy (DE) features were extracted from four wavebands (theta 4–8 Hz, alpha 8–13 Hz, beta 13–30 Hz, and gamma 30–49 Hz) to classify two emotional states (positive/negative). Five classifiers, namely Support Vector Machine (SVM), k-Nearest Neighbor (kNN), Naïve Bayesian (NB), Decision Tree (DT), and Logistic Regression (LR) were employed with DE features for the automated classification of two emotional states. In this work, we obtained the best average accuracy of 76.22% ± 2.06 with the SVM classifier in the classification of two states. Moreover, we observed from the results that the highest average accuracy score was produced with the gamma band, as previously reported in studies in EEG-based emotion recognition.
AtıfScopus29OpenAlex33İncele - MakaleYalnız künye2020Scopus SJRQ1A deep convolutional neural network model for automated identification of abnormal EEG signals
Yıldırım, Özal; Baloglu, Ulas Baran; Acharya, U. Rajendra
Electroencephalogram (EEG) is widely used to monitor the brain activities. The manual examination of these signals by experts is strenuous and time consuming. Hence, machine learning techniques can be used to improve the accuracy of detection. Nowadays, deep learning methodologies have been used in medical field to diagnose the health conditions precisely and aid the clinicians. In this study, a new deep one-dimensional convolutional neural network (1D CNN) model is proposed for the automatic recognition of normal and abnormal EEG signals. The proposed model is a complete end-to-end structure which classifies the EEG signals without requiring any feature extraction. In this study, we have used the EEG signals from temporal to occipital (T5–O1) single channel obtained from Temple University Hospital EEG Abnormal Corpus (v2.0.0) EEG dataset to develop the 1D CNN model. Our developed model has yielded the classification error rate of 20.66% in classifying the normal and abnormal EEG signals.
AtıfScopus164OpenAlex211İncele - Derleme MakaleYayıncıda açık erişim2020Scopus SJRQ1Application of deep learning techniques for heartbeats detection using ECG signals-analysis and review
Murat, Fatma; Yildirim, Ozal; Talo, Muhammed; Baloglu, Ulas Baran; Demir, Yakup; Acharya, U. Rajendra
Deep learning models have become a popular mode to classify electrocardiogram (ECG) data. Investigators have used a variety of deep learning techniques for this application. Herein, a detailed examination of deep learning methods for ECG arrhythmia detection is provided. Approaches used by investigators are examined, and their contributions to the field are detailed. For this purpose, journal papers have been surveyed according to the methods used. In addition, various deep learning models and experimental studies are described and discussed. A five-class ECG dataset containing 100,022 beats was then utilized for further analysis of deep learning techniques. The constructed models were examined with this dataset, and results are presented. This study therefore provides information concerning deep learning approaches used for arrhythmia classification, and suggestions for further research in this area.
AtıfScopus318OpenAlex328İncele - MakaleYalnız künye2019Scopus SJRQ1A new approach for arrhythmia classification using deep coded features and LSTM networks
Yildirim, Ozal; Baloglu, Ulas Baran; Tan, Ru-San; Ciaccio, Edward J.; Acharya, U. Rajendra
Background and objective: For diagnosis of arrhythmic heart problems, electrocardiogram (ECG)signals should be recorded and monitored. The long-term signal records obtained are analyzed by expert cardiologists. Devices such as the Holter monitor have limited hardware capabilities. For improved diagnostic capacity, it would be helpful to detect arrhythmic signals automatically. In this study, a novel approach is presented as a candidate solution for these issues. Methods: A convolutional auto-encoder (CAE)based nonlinear compression structure is implemented to reduce the signal size of arrhythmic beats. Long-short term memory (LSTM)classifiers are employed to automatically recognize arrhythmias using ECG features, which are deeply coded with the CAE network. Results: Based upon the coded ECG signals, both storage requirement and classification time were considerably reduced. In experimental studies conducted with the MIT-BIH arrhythmia database, ECG signals were compressed by an average 0.70% percentage root mean square difference (PRD)rate, and an accuracy of over 99.0% was observed. Conclusions: One of the significant contributions of this study is that the proposed approach can significantly reduce time duration when using LSTM networks for data analysis. Thus, a novel and effective approach was proposed for both ECG signal compression, and their high-performance automatic recognition, with very low computational cost.
AtıfScopus377OpenAlex388İncele - MakaleAçık Erişim2019Scopus SJRQ2Automated detection of diabetic subject using pre-trained 2D-CNN models with frequency spectrum images extracted from heart rate signals
Yildirim, Ozal; Talo, Muhammed; Ay, B.; Baloglu, Ulas Baran; Aydin, G.; Acharya, U. Rajendra
In this study, a deep-transfer learning approach is proposed for the automated diagnosis of diabetes mellitus (DM), using heart rate (HR) signals obtained from electrocardiogram (ECG) data. Recent progress in deep learning has contributed significantly to improvement in the quality of healthcare. In order for deep learning models to perform well, large datasets are required for training. However, a difficulty in the biomedical field is the lack of clinical data with expert annotation. A recent, commonly implemented technique to train deep learning models using small datasets is to transfer the weighting, developed from a large dataset, to the current model. This deep learning transfer strategy is generally employed for two-dimensional signals. Herein, the weighting of models pre-trained using two-dimensional large image data was applied to one-dimensional HR signals. The one-dimensional HR signals were then converted into frequency spectrum images, which were utilized for application to well-known pre-trained models, specifically: AlexNet, VggNet, ResNet, and DenseNet. The DenseNet pre-trained model yielded the highest classification average accuracy of 97.62%, and sensitivity of 100%, to detect DM subjects via HR signal recordings. In the future, we intend to further test this developed model by utilizing additional data along with cloud-based storage to diagnose DM via heart signal analysis.
AtıfScopus145OpenAlex152İncele - MakaleAçık Erişim2019Scopus SJRQ2Automated Depression Detection Using Deep Representation and Sequence Learning with EEG Signals
Ay, Betul; Yildirim, Ozal; Talo, Muhammed; Baloglu, Ulas Baran; Aydin, Galip; Puthankattil, Subha D.; Acharya, U. Rajendra
Depression affects large number of people across the world today and it is considered as the global problem. It is a mood disorder which can be detected using electroencephalogram (EEG) signals. The manual detection of depression by analyzing the EEG signals requires lot of experience, tedious and time consuming. Hence, a fully automated depression diagnosis system developed using EEG signals will help the clinicians. Therefore, we propose a deep hybrid model developed using convolutional neural network (CNN) and long-short term memory (LSTM) architectures to detect depression using EEG signals. In the deep model, temporal properties of the signals are learned with CNN layers and the sequence learning process is provided through the LSTM layers. In this work, we have used EEG signals obtained from left and right hemispheres of the brain. Our work has provided 99.12% and 97.66% classification accuracies for the right and left hemisphere EEG signals respectively. Hence, we can conclude that the developed CNN-LSTM model is accurate and fast in detecting the depression using EEG signals. It can be employed in psychiatry wards of the hospitals to detect the depression using EEG signals accurately and thus aid the psychiatrists.
AtıfScopus279OpenAlex291İncele - MakaleYalnız künye2018Scopus SJRQ2Arrhythmia detection using deep convolutional neural network with long duration ECG signals
Yıldırım, Özal; Pławiak, Paweł; Tan, Ru-San; Acharya, U. Rajendra
This article presents a new deep learning approach for cardiac arrhythmia (17 classes) detection based on long-duration electrocardiography (ECG) signal analysis. Cardiovascular disease prevention is one of the most important tasks of any health care system as about 50 million people are at risk of heart disease in the world. Although automatic analysis of ECG signal is very popular, current methods are not satisfactory. The goal of our research was to design a new method based on deep learning to efficiently and quickly classify cardiac arrhythmias. Described research are based on 1000 ECG signal fragments from the MIT - BIH Arrhythmia database for one lead (MLII) from 45 persons. Approach based on the analysis of 10-s ECG signal fragments (not a single QRS complex) is applied (on average, 13 times less classifications/analysis). A complete end-to-end structure was designed instead of the hand-crafted feature extraction and selection used in traditional methods. Our main contribution is to design a new 1D-Convolutional Neural Network model (1D-CNN). The proposed method is 1) efficient, 2) fast (real-time classification) 3) non-complex and 4) simple to use (combined feature extraction and selection, and classification in one stage). Deep 1D-CNN achieved a recognition overall accuracy of 17 cardiac arrhythmia disorders (classes) at a level of 91.33% and classification time per single sample of 0.015 s. Compared to the current research, our results are one of the best results to date, and our solution can be implemented in mobile devices and cloud computing.
AtıfScopus801OpenAlex854İncele - MakaleYayıncıda açık erişim2018Scopus SJRQ2Application of Computational Intelligence Methods for the Automated Identification of Paper-Ink Samples Based on LIBS
Rzecki, Krzysztof; Sośnicki, Tomasz; Baran, Mateusz; Niedźwiecki, Michał; Król, Małgorzata; Łojewski, Tomasz; Acharya, U. Rajendra; Yildirim, Özal; Pławiak, Paweł
Laser-induced breakdown spectroscopy (LIBS) is an important analysis technique with applications in many industrial branches and fields of scientific research. Nowadays, the advantages of LIBS are impaired by the main drawback in the interpretation of obtained spectra and identification of observed spectral lines. This procedure is highly time-consuming since it is essentially based on the comparison of lines present in the spectrum with the literature database. This paper proposes the use of various computational intelligence methods to develop a reliable and fast classification of quasi-destructively acquired LIBS spectra into a set of predefined classes. We focus on a specific problem of classification of paper-ink samples into 30 separate, predefined classes. For each of 30 classes (10 pens of each of 5 ink types combined with 10 sheets of 5 paper types plus empty pages), 100 LIBS spectra are collected. Four variants of preprocessing, seven classifiers (decision trees, random forest, k-nearest neighbor, support vector machine, probabilistic neural network, multi-layer perceptron, and generalized regression neural network), 5-fold stratified cross-validation, and a test on an independent set (for methods evaluation) scenarios are employed. Our developed system yielded an accuracy of 99.08%, obtained using the random forest classifier. Our results clearly demonstrates that machine learning methods can be used to identify the paper-ink samples based on LIBS reliably at a faster rate.
AtıfScopus39İncele - MakaleYalnız künye2018Scopus SJRQ3An efficient compression of ECG signals using deep convolutional autoencoders
Yildirim, Ozal; Tan, Ru San; Acharya, U. Rajendra
Background and objective: Advances in information technology have facilitated the retrieval and processing of biomedical data. Especially with wearable technologies and mobile platforms, we are able to follow our healthcare data, such as electrocardiograms (ECG), in real time. However, the hardware resources of these technologies are limited. For this reason, the optimal storage and safe transmission of the personal health data is critical. This study proposes a new deep convolutional autoencoder (CAE) model for compressing ECG signals. Methods: In this paper, a deep network structure of 27 layers consisting of encoder and decoder parts is designed. In the encoder section of this model, the signals are reduced to low-dimensional vectors; and in the decoder section, the signals are reconstructed. The deep learning approach provides the representations of the low and high levels of signals in the hidden layers of the model. Hence, the original signal can be reconstructed with minimal loss. Very different from traditional linear transformation methods, a deep compression approach implies that it can learn to use different ECG records automatically. Results: The performance was evaluated on an experimental data set comprising 4800 ECG fragments from 48 unique clinical patients. The compression rate (CR) of the proposed model was 32.25, and the average PRD value was 2.73%. These favourable observation suggest that our deep model can allow secure data transfer in a low-dimensional form to remote medical centers. We present an effective compression approach that can potentially be used in wearable devices, e-health applications, telemetry and Holter systems.
AtıfScopus201OpenAlex206İncele