Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleAçık Erişim2023Scopus SJRQ2Shape Memory Polymer-Based Nanocomposites Magnetically Enhanced with Fe3O4 Nanoparticles
Pekdemir, Mustafa Ersin; Aydin, Derya; Selçuk Pekdemir, Sibel; Erecevit Sönmez, Pınar; Aksoy, Edanur
This work aimed to investigate the effect of magnetic Fe3O4 nanoparticles (MNP), which are known to have a wide range of applications in recent years, on nanocomposite films prepared with shape memory polymers. Herein, PLA–PEG blend nanocomposite films were prepared by solution casting method using MNP at different ratios. PLA–PEG Blend/MNP nanocomposite films were characterized with Attenuated total reflection infrared spectroscopy (ATR-IR) to determine the –C=O stretching of PLA and Fe–O stretching signals of Fe3O4. The thermal stability, morphology, and magnetic behavior were studied by comparing the results among PLA–PEG blend, PLA–PEG blend/MNP nanocomposite with thermogravimetric analyses (TGA), differential scanning calorimetry (DSC), scanning electron microscopy (SEM), and a vibrating sample magnetometer (VSM), respectively. The effect of MNP on the shape memory properties of PLA/PEG blend was investigated. Moreover, the comparison of antimicrobial activity between PLA/PEG blend and PLA–PEG blend/MNP nanocomposite films were conducted by the disk diffusion method. The results showed that MNP increased the thermal stability of the PLA/PEG blend and the nanocomposites inhibited the growth of C.albicans microorganism. Graphical Abstract: [Figure not available: see fulltext.].
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İncele - MakaleAçık Erişim2022Scopus SJRQ2Synthesis, characterization, and evaluation of antimicrobial performance of N-[3-(dimethylamino)propyl]methacrylamide based copolymer on pathogens
Pıhtılı, Güzin; Erecevit Sönmez, Pınar; Biryan, Fatih; Torğut, Gülben
In this study, poly{N-[3-(dimethylamino) propylmethacrylamide-co-acrylonitrile}; [P(DMAPMA-co-AcN)] copolymer was polymerized by free radical polymerization (FRP) in the presence of azobisisobutyronitrile (AIBN) initiator at 60°C. The structure of the synthesized polymer was characterized by the Fourier transform infrared (FT-IR), differential scanning calorimetry (DSC), and thermogravimetric analysis (TGA) methods. The bactericidal and fungicidal effects of the solutions prepared by adding methanol to this copolymer to prevent the growth of pathogenic bacteria, yeast, and fungi were evaluated by disk diffusion and broth microdilution method. Since the resistance of bacteria, yeast and fungi, which adversely affect human health, to antibiotics is an important issue, and there has not been any study on the antimicrobial properties of this copolymer, it has directed us to investigate its antimicrobial properties. According to antimicrobial susceptibility tests: The polymer solution showed a broad spectrum of antimicrobial action with 12.3–14.3 mm/inhibition zone diameter on Pseudomonas aeruginosa, Klepsiella pneumoniae, Enterococcus faecalis bacteria, Candida tropicalis, Epidermophyton floccosum yeast and fungi and showed a narrow spectrum of effect on inhibition of the growth of Candida albicans with 10.3 mm/inhibition zone diameter. No antimicrobial effects were observed on Staphylococcus aureus. The minimum inhibition concentration (MIC) value on the test microorganisms was determined as 125–31.25 μl. The data obtained prove that the polymer is in the same group as the interaction of bactericidal and fungicidal drugs. It is also important as a polymer with antimicrobial properties. This study aimed to produce a new polymer with antimicrobial properties. This polymer can be a new and yielding antimicrobial representative in different areas.
AtıfScopus1WoS1OpenAlex1İncele - MakaleYalnız künye2020Scopus SJRQ4Preservative effect of coriander essential oil applied in different proportions on the storage of rainbow trout (Oncorhynchus mykiss) fillets
Kuzgun, Nermin Karaton; Erecevit Sönmez, Pınar; Tanyildizi, Muhammet Şaban
Aim of this study, the sensorial, microbiological, and chemical features during shelf life at 2 ± 2 °C of rainbow trout fillets samples treatment with coriander essential oils were examined of protective effect of oils. According to the findings of the research, the storage during of fillets ended on day 9th, that of control on day 12th, that of samples applied with coriander oils 0.1% on day 15th, which of fillets applied with coriander oils 0.25% and applied with coriander oils 0.5% on day 18th. The minimum number of bacteria, values of TVB-N and TBA were founded in trout fillets treatment with 0.5% coriander essential oil. In terms of the sensory quality of the fillets, as assessed by panelists participating in the panel, it was detected that highest point was given to the fillets groups to which coriander essential oil of 0.5% had been enforced, and as a result, with this application, it was underlined that was obtained in a positive direction of a flavor very different other than ordinary fish flavor by panelists.
AtıfScopus5WoS2İncele - MakaleAçık Erişim2020Scopus SJRQ2Synthesis, and antimicrobial and anticancer activities of sodium acrylate copolymers
Torğut, Gülben; Pıhtılı, Güzin; Erecevit Sönmez, Pınar; Erden, Yavuz; Kırbağ, Sevda
This study was designed to synthesize poly(sodium acrylate-co-N-isopropylacrylamide) via aqueous free-radical polymerization using the 2,2′-azobisisobutyronitrile initiator system at 60°C. The structural characterization of the copolymer was determined by Fourier-transform infrared spectroscopy. The polymer was synthesized in two different ratios, namely, poly(NaAc-co-NIPA1:1) and poly(NaAc-co-NIPA2:1), to investigate whether it affects their antibacterial–antifungal activities and anti-tumour effects. When the antimicrobial activities of different proportions of the copolymer extracts prepared with pure water were examined using the agar disc diffusion sensitivity test (at 120 μL: 10.8 mg/µL), it was observed that they had effect at increasing rates against all the bacteria, yeasts and dermatophyte fungi such as Staphylococcus aureus COWAN 1, Staphylococcus cohnii ATCC 29974, Bacillus megaterium DSM 32, Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Klebsiella pneumoniae FMC 5, Pseudomonas aeruginosa DMS 50071 SCOTTA, Candida albicans FMC 17, Candida glabrata ATCC 66032, Trichophyton sp. and Epidermophyton sp. The results of this study revealed that the obtained copolymers have significant effects on the treatment of diseases. In addition, the anti-tumour activities of the poly(NaAc-co-NIPA1:1) copolymer on human breast (MCF-7) and ovarian cancer (A-2780) cell line were specified and it was determined that high doses of the copolymer showed anti-tumour effects on both types of cancer cell lines. Also, this article reviews its antimicrobial and anticancer activities that will be of help for future scientists.
AtıfScopus3WoS3OpenAlex6İncele - MakaleAçık Erişim2019Scopus SJRQ3Antifungal and antibacterial effect of dodder (Cuscuta campestris) used for hepatitis treatment of mothers and newborn infants in Province Mardin in Turkey; [Türkiye'de Mardin ilindeki annelerin ve yenidoğan bebeklerin sarılık tedavisinde kullanılan küsküt'ün (Cuscuta campestris) antifungal ve antibakteriyel etkileri]
Erecevit Sönmez, Pınar; Kirbağ, Sevda; İnci, Şule
Dodder is a plant used for the hepatitis treatment in new born infants in and around Mardin. The aim of this research to determine the antifungal and antibacterial effects of traditionally used dooder is known as a regional folk remedy. Thus and so, the efficacy of the drug has been demonstrated by the inclusion of natural therapeutic antimicrobial agents such as anti-inflammatory and wound healing, including infectious diseases. The antimicrobial effects of these plant was analyzed against bacteria, yeast and dermatopyta fungi by the agar disc diffusion method. The nominal concentration of the plant to prevent from the development of microorganisms was detected with the broth microdulitions method. It was determined that it had sensitive and moderately sensitive antimicrobial effect against all of microrganisms (13-19.66 mm/inhibition zone), growth of tested microrganisms were inhibited at 50-6.25 µL.It is though that this natural herbal resource can light the way for treatment of several diseases and direct the next studies because of having the potential for being used as a new antimicrobial agent.
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