Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleAçık Erişim2025Scopus SJRQ2Effects of ZrN and DLC coatings on morphostructural, corrosion, cell viability, and antibacterial properties of Ti6Al4V scaffolds
Aslan, Naim; Aksakal, Bünyamin; Cihangir, Salih; Fidan, Ferzan; Yilmazer, Yasemin
Lightweight and functional metallic materials are consistently favored and attract significant attention in the biomedical field. This study investigates the influence of ZrN and DLC coatings on Ti6Al4V scaffolds with varying porosities (40%, 50%, 60%) for biomedical applications. PVD-deposited coatings exhibited distinct growth mechanisms: High-resolution SEM-FIB analyses revealed columnar ZrN structures due to limited adatom mobility, while DLC formed conformal, amorphous layers via high-energy carbon species. Corrosion resistance decreased in 40% porous DLC and 60% porous ZrN-coated samples, likely due to coating defects and increased electrolyte access through open pores. ZrN coatings showed superior antibacterial activity and attributed to surface reactivity and potential ion release. In contrast, the uncoated 60% porous scaffolds demonstrated highest cell viability, suggesting that excessive coating on highly porous structures may hinder cell–material interactions. Furthermore, the cytotoxicity evaluations indicated that uncoated scaffolds exhibited the highest cell viability (77.51%) at 60% porosity after 48 hours, with ZrN coatings demonstrating better efficacy compared to DLC in the 50% and 60% porosity groups.
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İncele - MakaleAçık Erişim2024Effects of Porosity and Boron Reinforcement in AISI 316L Stainless Steel for Biomedical Applications
Aslan, Naim; Aksakal, Bunyamin; Fidan, Ferzan
AISI 316L stainless steel (SS) is one of the most widely used biomaterials in the manufacture of implants and biomaterials. It has advantages over equivalent biomaterials such as low cost, good mechanical properties and biocompatibility. The pores found in porous biomaterials provide mechanical interlock, ensuring strong attachment of the implant to the tissue. In this study, 20%, 30% and 40% by volume of polyvinyl alcohol (PVA) and Boron powder were added into 316L powder to obtain porous SS implant. To investigate the effect of porosity and boron effect on the stainless-steel implant material, the samples produced in PVA and Boron added groups, were sintered at 1180 oC under an argon atmosphere. With the evaporation of PVA in the structure, porous and boron added samples were obtained in two groups. Finally, the samples were subjected to Brinell hardness and compression tests and analyzed by SEM, EDS and XRD. As a result of the hardness tests, the highest values were measured as 37.006, 31.32, 25.28 HB. 39.5, 34.5, 26.2 MPa strengths were measured for 20%, 30% and 40% porous samples respectively.
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İncele - MakaleAçık Erişim2023Scopus SJRQ3Morpho-structural and compressive mechanical properties of graphene oxide reinforced hydroxyapatite scaffolds for bone tissue applications
Fidan, Ferzan; Aslan, Naim; Koç, Mümin Mehmet
Hydroxyapatite (HA) is a unique material that has the potential to be used to replace bones and teeth in the field of orthopedics and dentistry since HA exhibits quite similar biological and chemical characteristics to human bone. Hydroxyapatite ceramics are bioactive materials used to repair damaged human tissue. The pores in the porous hydroxyapatite ceramics provide a mechanical interlock, enabling a solid bond and fixation between the implant and bone. In this study, 0.5wt%, 1wt%, and 1.5wt% graphene oxide (GO) reinforced porous HA structures were obtained using the space-holder method to increase the strength of hydroxyapatite with low mechanical strength. NaCl was used as a spacer, and PEG 400 as a binder. Scaffold structures with 40% porosity rates were sintered at 1000 °C under vacuum. Finally, a compression test was applied to the samples which were previously analyzed by SEM, EDS and XRD. The compressive strengths of 0.5%, 1%, and 1.5% graphene oxide reinforced porous HA samples were determined between 8.04 and 31.14 MPa. The highest compressive strength was recorded as 31.14 MPa in the 1% GO added sample, and the lowest compressive strength was recorded as 8.04 MPa in the 1.5% GO added sample. In addition, it was understood that the mechanical properties did not increase regularly with the increase of graphene oxide reinforcing.
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