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• MakaleAçık Erişim2025/r/munzur/4863
  Antigenotoxic Effects of Stachys viscosa (Lamiaceae), a potential medicinal plant in Drosophila melanogaster

  Karabulut, Aygul Kilic; Açar, Mikail

  This research aimed to examine the anti-genotoxic properties of Stachys viscosa, a plant of the Lamiaceae family, which has medicinal and aromatic properties and is widely used in cosmetics, food, and pharmaceutical industries. The Drosophila wing somatic mutation and recombination test (SMART), an in vivo tool for evaluating somatic mutation and recombination, was employed. The antigenotoxic effect of the S. viscosa plant against mitomycin C (MMC) mutagen was investigated. The study evaluated doses of 5 mg, 15 mg, 45 mg, and 60 mg of S. viscosa, concluding that doses of 45 mg and 60 mg effectively mitigated DNA damage induced by MMC. At doses of 45 mg and 65 mg, the total number of spots caused by MMC was suppressed by 8.21% and 13.17%, respectively. The data collected indicate that the S. viscosa plant possesses certain anti-genotoxic properties.

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