Yazarlar
- Koçak, Berna(2)
- Keçeci, Ali(1)
- İpek, Yeliz.(1)
Yayınlar
- MakaleYalnız künye2025Scopus SJRQ3Eco-Friendly and Practical Electrochemical Determination of Lactic Acid in Milk Using Boron Doped Diamond Electrode
İpek, Yeliz.; Koçak, Berna; Keçeci, Ali
In this study, an economical, environmentally friendly, sensitive, selective, and rapid voltammetric quantitative analysis method was developed using a boron doped diamond electrode to determine lactic acid (LA). Two linear working ranges were determined for LA determination in phosphate buffer solution (PBS, pH of 2). The first linear working range (LR1) was between concentrations of 1.5 × 10−6–8 × 10−6 mol· L−1, with a detection limit of 1.3 × 10−6 mol·L−1, and the limit of quantification (LOQ) was found to be 4.4 µmol· L−1. The second linear working range (LR2) was determined in the concentration range of 8.0–89.2 µmol·L−1. LOD was calculated as 15.8 µmol·L−1, and the LOQ value was calculated as 52.6 µmol·L−1 in the LR2. Intraday repeatability of the BDD electrode for LA determination was (RSD) 6.8% in LR1 and 11.8% in LR2. The interday repeatabilities of the BDD electrode in LR1 and LR2 were calculated as 7.7% and 4.7%, respectively. The developed electrochemical sensor was successfully applied for the determination of LA in milk sample. The sensor exhibited a short response time of about 10 s in PBS at pH 2. The recovery values of LA in PBS and milk sample were 97.3% and 96.1%, respectively.
AtıfScopus2WoS2OpenAlex2
İncele - MakaleYalnız künye2023Scopus SJRQ3A Selective and Sensitive Electrochemical Sensor for Pyridoxine Hydrochloride (Vitamin B6) in Pharmaceutic Tablet
Koçak, Berna
In this study, a copper (II) oxide-glutardialdehyde modified boron doped diamond electrode was used as a sensor for the electroanalysis of pyridoxine hydrochloride (vitamin B6) for the first time. A copper oxide-glutardialdehyde modified boron doped diamond electrode (CuO-GA2/BDDE) was prepared by a simple drop casting method on boron diamond electrode (BDDE) by suspending CuO with glutardialdehyde (CuO-GA2). The electrochemical behavior of vitamin B6 was examined using cyclic voltammetry (CV) and its electrochemical determination was found by differential pulse voltammetry (DPV). Under optimum experimental conditions, the linear working range of vitamin B6 on CuO-GA2/BDDE via the DPV method was calculated as 5.96×10−6–3.75×10−4 mol.L−1. The limit of detection (LOD) was calculated as 1.99×10−7 mol.L−1. In order to demonstrate the selectivity of the method improved for the quantitative determination of vitamin B6 on the CuO-GA2/BDDE, the interference effect of some cations (Zn2+, Cu2+, Pb2+) and anions (NO3−, Cl−) was investigated via the DPV method. The improved electrode was successfully used for the electroanalysis of vitamin B6 in a tablet sample of the commercial Tribeksol® (deva) (250/250/1 mg B1+B6+B12).
AtıfScopus7WoS6OpenAlex6İncele