Yazarlar

• Aydin, Ali(1)
• Bülbül, A.S.(1)
• Ceylan, Y.(1)
• Karadag, Ahmet(1)
• Karadağ, A.(1)
• Korkmaz, N.(1)
• Korkmaz, Sengul Asian(1)
• Korkmaz, Ş.A.(1)
• Soylu, Mustafa Serkan(1)
• Yerli, Yusuf(1)
• İmamoğlu, R.(1)

• MakaleAçık Erişim2022Scopus SJRQ4/r/munzur/3008
  New dinuclear cyanido complexes with amine alcohol ligand: Synthesis, characterization and biotechnological application potential

  Korkmaz, N.; Korkmaz, Ş.A.; Ceylan, Y.; İmamoğlu, R.; Bülbül, A.S.; Karadağ, A.

  In this study, the cyanido complexes given by the formula [Ni(Abut)Ni(CN)4 ]·8H2 O (C1), [Cu(Abut)2 Ni(CN)4 ]·7H2 O (C2), [Zn(Abut)Ni(CN)4 ]·8H2 O (C3) and [Cd(Abut)Ni(CN)4 ]·7H2 O (C4) were ob-tained by microwave synthesis method. The powder forms of the complexes were characterized by elemental, FT-IR spectroscopy, and thermal analysis. And also antibacterial, antibiofilm and anticancer activities were investigated. The splitting stretching bands of cyanido groups in the FT-IR spectra of C1-C4 indicated the assets of terminal and end cyanido groups. The antibacterial activities of C1-C4 were tested with nine Gram negative and six Gram positive bacteria. The most efficient antibacterial activity of complexes was observed at 1000 µg/ml-1 concentration. Anticancer activity was tested using HeLa cell line and MTT test. The studied cyanide complexes have been shown to decrease the viability of HeLa cells with IC50 values 14.86, 6.5, 7.2 and 19.2 µg/ml for C1, C2, C3 and C4 complex, respectively.

  İncele
• MakaleYalnız künye2016Scopus SJRQ2/r/munzur/4227
  Binuclear cyanido complexes containing [Pt(CN)4]2- building block: Synthesis, crystal structures, magnetic properties and anticancer activities

  Korkmaz, Sengul Asian; Karadag, Ahmet; Aydin, Ali; Yerli, Yusuf; Soylu, Mustafa Serkan

  Five new complexes of composition [Ni(N-bishydeten)Pt(CN)(4)] (1), [Ni(N-bishydeten)(2)][Pt(CN)(4)] (2), [Cu (N-bishydeten)Pt(CN)(4)] (3), [Cu(N-bishydeten)(2)][Pt(CN)(4)] (4) and [Cd(N-bishydeten)(2)][Pt(CN)(4)] (5) (N-bishydeten = N,N-bis(2-hydroxyethyl)-ethylenediamine) have been obtained and characterized by IR and EPR spectroscopies, elemental and thermal analysis and magnetic measurements. X-ray studies of 2 and 3 exhibited different structures and two different coordination modes of N-bishydeten ancillary ligand with a ratio of M:L. While N-bishydeten acts as a tetradentate with N', N', O and O' atoms in a molar ratio of 1:1 formed 2,2-CT-type zigzag chain for 3, it behaves tridentate ligand by ending up with six coordinated Ni-II center in a complex salt by using 1:2 M ratio for 2. None of the 1 and 3 complexes produced in this study showed sufficient anticancer activity but all did exhibit apoptotic properties and one of them also performed low cytotoxic activity against cell tested. (C) 2016 Elsevier B.V. All rights reserved.

  AtıfWoS7·OpenAlex8

  İncele