Yazarlar

• Paksoy, Mehmet Yavuz(3)
• Ak, Gunes(1)
• Aydin, Sinem(1)
• Cakır, Oguz(1)
• Ceylan, Ramazan(1)
• Jugreet, Sharmeen(1)
• Karlıoğlu Kılıç, Nurgül(1)
• Mahomoodally, Mohamad Fawzi(1)
• Ouelbani, Rayene(1)
• Sevindik, Emre(1)
• Sinan, Kouadio Ibrahime(1)
• Sokmen, Bahar Bilgin(1)
• Tuncalı Yaman, Tutku(1)
• Yılmaz Dağdeviren, Rüya(1)
• Yılmaz, Mustafa Abdullah(1)
• Zengin, Gokhan(1)

• MakaleAçık Erişim2021Scopus SJRQ2/r/munzur/3602
  Pollen morphology of eight endemic Inula L. (Asteraceae) species in Turkey

  Karlıoğlu Kılıç, Nurgül; Yılmaz Dağdeviren, Rüya; Paksoy, Mehmet Yavuz; Tuncalı Yaman, Tutku

  The pollen morphology of eight endemic species of the genus Inula L. (Asteraceae)–I. helenium subsp. orgyalis (Boiss.) Grierson, I. helenium subsp. vanensis Grierson, I. macrocephala Boiss. & Kotschy ex Boiss., I. discoidea Boiss., I. sarana Boiss., I. fragilis Boiss. & Hausskn., I. anatolica Boiss. and I. sechmenii Hartvig & Strid–distributed in Turkey was studied with light microscopy and scanning electron microscopy. We found that the pollen of these Inula taxa are prolate-spheroidal in shape (except in Inula discoidea), with the polar axis ranging from 19.18 to 33.14 µm and the equatorial diameter ranging from 18.54 to 32.92 µm. The pollen grains are tricolporate and their ornamentation is echinate. The exine thickness ranges from 0.87 to 2.07 µm. As this study demonstrates, results of Principal Component Analysis are revealed that some of the pollen characters, such as spine length and width, are significant morphological characters for taxonomic discrimination of the eight endemic Inula taxa. According to cluster analysis, two main groups of examined taxa are constituted.

  AtıfScopus9·WoS9·OpenAlex10

  İncele
• MakaleYalnız künye2021Scopus SJRQ3/r/munzur/2898
  Enzyme inhibition and antioxidant functionality of eleven Inula species based on chemical components and chemometric insights

  Ceylan, Ramazan; Zengin, Gokhan; Mahomoodally, Mohamad Fawzi; Sinan, Kouadio Ibrahime; Ak, Gunes; Jugreet, Sharmeen; Cakır, Oguz; Ouelbani, Rayene; Paksoy, Mehmet Yavuz; Yılmaz, Mustafa Abdullah

  The members of the genus Inula have been widely used in traditional medicinal. In the present study, 11 Inula species were investigated for their phytochemical composition, antioxidant and enzyme inhibitory effects. While quinic acid was the principal compound in I. anatolica, I. britannica, I. inuloides, I. oculus-christi, I. peacockiana, I. sechmenii, I. thapsoides and I. viscidula extracts (22.43–42.02 mg/g dry extract (DE)), I. aucheriana and I. discoidea extracts contained rutin as their most abundant compound (23.28 and 79.10 mg/g extract, respectively). Interestingly, all the Inula extracts were active inhibitors of the five key clinical enzymes (acetylcholinesterase (3.56–5.13 mg galantamine equivalent (GALAE)/g), butyrylcholinesterase (1.49–7.34 mg GALAE/g), tyrosinase (112.31–122.13 mg kojic acid equivalent (KAE)/g), α-glucosidase (0.77–2.08 mmol acarbose equivalent (ACAE)/g) and α-amylase (0.73–0.90 mmol ACAE/g)). Furthermore, the extracts were observed to exhibit substantial antioxidant capacity (1,1-diphenyl-2-picrylhydrazyl (DPPH): 58.99–188.22 mg trolox equivalent (TE)/g); 2,2-azino-bis(3-ethylbenzo-thiazoline-6-sulfonic acid) (ABTS): 90.51–220.97 mg TE/g; cupric reducing antioxidant capacity (CUPRAC): 169.88–460.53 mg TE/g; ferric reducing antioxidant power (FRAP): 81.57–237.99 mg TE/g; metal chelating activity: 8.31–25.39 mg ethylenediamine tetraacetate equivalent (EDTAE)/g; phosphomolybdenum: 1.55–2.49 mmol TE/g). In conclusion, the Inula species studied herein showed promising pharmacological potentials justified by the presence of a panoply of bioactive compounds.

  AtıfScopus60·OpenAlex60

  İncele
• MakaleAçık Erişim2020Scopus SJRQ3/r/munzur/3304
  ANTI-UREASE, TOTAL PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITIES OF SOME Inula L. (ASTERACEAE) TAXA IN TURKEY

  Sevindik, Emre; Aydin, Sinem; Paksoy, Mehmet Yavuz; Sokmen, Bahar Bilgin

  The genus Inula belongs to family Asteraceae and it is medicinally important because it possesses cytotoxic, anticancer, hepatoprotective, antibacterial and anti-inflammatory properties. The aim of this research was to explore antioxidant and anti-urease activities of fifteen Inula taxa in Turkey. Ethanol extracts of Inula taxa were obtained by Soxhlet extraction. Antioxidant activity was determined through total antioxidant activity, total phenolic content and copper reducing antioxidant capacity (CUPRAC) analyses. The highest total phenolic content and total antioxidant capacity were found in I. orientalis (158.54±0.002 µg GAE/mL) and I. macrocephala (189.16±0.002 µg AAE/mL). CUPRAC activity increases with the increasing concentration of the extracts and the standard. Moreover, all the tested plants exhibited better anti-urease activity than standard thiourea except for I. anatolica and I. thapsoides subsp. thapsoides. Results obtained from this study demonstrate that Inula species might be utilized as a probable natural source in the pharmaceutical and food industries but further and more specific studies are needed to determine active antioxidative and anti-urease compounds in the extracts.

  AtıfScopus8·WoS7·OpenAlex10

  İncele