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- MakaleAçık Erişim2026Scopus SJRQ1Dietary exposure and health risk assessment of fumonisins through the consumption of maize and maize-based gluten-free products in individuals with celiac disease
Tuyben, Eylem Ezgi; Sevim, Sumeyra; Macit, Arife; Kizil, Mevlude
Introduction: Individuals with celiac disease (CD) must adhere to a gluten-free diet (GFD) and are therefore at high risk of fumonisin exposure due to their high consumption of maize and maize-based products. This study aimed to determine the concentrations of fumonisins (FB1, FB2, and FB3) in packaged gluten-free (GF) maize and maizebased products sold in Turkey and to assess dietary exposure and health risks in adults with CD using a probabilistic approach. Methods: Fumonisin concentrations of 51 GF products were analyzed by Enzyme-Linked Immonosorbent Assay (ELISA) and daily food consumption data were collected from 67 individuals with CD through a food frequency questionnaire. Exposure was estimated using Estimated Daily Intake (EDI) values and probabilistic risk assessment with Monte Carlo simulation. Results: The highest fumonisins concentrations were detected in the pasta/rice/bulgur group, while the flour/starch group was the food group contributed most to total fumonisins exposure due to higher consumption. Although the average EDI values were below the Tolerable Daily Intake (TDI; 1 μg/kg bw/day) set by European Food Safety Authority’s (EFSA) and Provisional maximum tolerable daily intakes (PMTDI; 2 μg/kg bw/day) established by Joint Expert Committee on Food Additives’s (JECFA) values, individuals at the 95th percentile approached 132.88–167.89% of the PMTDI value in the flour/starch group and 79.00–82.38% in the pasta/rice/bulgur group. Discussion: These findings highlight the need for continuous monitoring and stricter regulatory oversight and dietary guidance to protect vulnerable populations.
- MakaleYalnız künye2025Scopus SJRQ2A flexible parameter estimation method for the Farlie-Gumbel-Morgenstern copula: a simulation study
Susam, Selim Orhun
This research presents a minimum distance method based on the Bernstein empirical copula process for estimating the dependence parameter of the Farlie-Gumbel-Morgenstein copula. Also, this study examines its performance through a comprehensive Monte Carlo simulation study. The findings in this paper demonstrate that selecting the optimal degree of the Bernstein empirical copula has a significant impact on the performance of the new estimation method. The proposed estimator achieves optimal performance in terms of mean squared error (MSE) for the parameter range (Formula presented.) in small sample sizes, while outside this range, its performance varies depending on the degree of the Bernstein empirical copula. Finally, we apply the new method to real data for illustrative purposes.
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İncele - MakaleYalnız künye2023Scopus SJRQ3On the weighted tests of independence based on Bernstein empirical copula
Hudaverdi, Burcu; Susam, Selim Orhun
In this article, we propose a flexible weighted test of independence based on Cramér-von Mises statistic of the Bernstein empirical copula process. We investigate the asymptotic properties of the new weighted test. A Monte Carlo study is conducted to measure the power performance of the new test under various dependence structures and also to compare the performance with some other alternative tests. The effects of the weights and the selection of optimal Bernstein polynomial degree are significantly influencing the power of the test according to the particular type of dependence. Finally, the procedure is also applied to a dataset on diabetes for illustrative purpose.
AtıfScopus8WoS8OpenAlex7İncele - MakaleYalnız künye2020Scopus SJRQ1Evaluation of the radiation shielding capabilities of the Na2B4O7–SiO2–MoO3-Dy2O3 glass quaternary using Geant4 simulation code and Phy-X/PSD database
Aşkın, A.
The important gamma and neutron radiation shielding parameters of the Dy3+ doped (65-x)Na2B4O7–15SiO2–20MoO3-xDy2O3 (x = 0, 5, 10, 15, 20 mol%) glass quaternary system were investigated to provide decisive information for their application in radiation environment. Gamma and neutron attenuation properties of the glass systems studied here were evaluated in terms of the mass attenuation coefficient (μm), transmission fraction (TF), half value layer (HVL), mean free path (MFP), effective atomic number (Zeff), exposure buildup factors (EBF) and fast neutron removal cross-section (∑R) parameters. Investigation of the each aforementioned parameter was performed thanks to the utilization of Monte Carlo simulations along with the Phy-X/PSD database. The photon attenuation characteristics were evaluated for gamma ray energies varying between 0.284 and 5.0 MeV. This study indicated that increase of the Dy2O3 content from 0% to 20% mole, enhances the gamma shielding capability due to the increase of the parameters μm and Zeff. In this study it was also observed that ∑R increases from 0.099 to 0.107 cm−1 as the molar fraction of Dy2O3 increases.
AtıfScopus75WoS74OpenAlex82İncele - MakaleYalnız künye2020Scopus SJRQ1Gamma and neutron shielding characterizations of the Ag2O–V2O5–MoO3–TeO2 quaternary tellurite glass system with the Geant4 simulation toolkit and Phy-X software
Aşkın, A.
Gamma and neutron shielding potential of the newly developed xAg2O-(35-x)[0.5V2O5-0.5MoO3]-65TeO2 (x = 0, 5, 10, 15, 20 and 25 mol%) quaternary tellurite glass system were investigated computationally by means of Geant4 Monte Carlo simulations and Phy-X software. Gamma ray shielding capabilities were studied via the mass attenuation coefficient (μm), transmission fractions (T), effective atomic number (Zeff), half value layer (HVL) and mean free path (MFP) parameters and for the photon energies of 0.284, 0.356, 0.511, 0.662, 1.173 and 1.330 MeV. Fast neutron removal cross-section (∑R) parameter of the glasses was calculated to assess the neutron shielding capabilities. The results of this study revealed that tellurite glass containing 25% moles of Ag2O has highest μm and Zeff and lowest T, HVL and MFP values due to the high atomic number of Ag. In this study it was also seen that the ∑R of the investigated glass system increases with the increase of Ag2O fraction and ∑R values of the studied glasses are higher than barite added concrete and close to the ∑R of the PbO added borate glasses.
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