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Koleksiyondaki öğeler
- MakaleYalnız künye2024Scopus SJRQ2Optimizing the thermoelectric performance of Bi-Sb-Te thin films through compositional engineering
Yüzüak, Gizem Durak; Çetin, Mehmet; Yüzüak, Ercüment
The objective of the present investigation was to systematically investigate the structural and thermoelectric (TE) properties of BixSb2-xTe3 thin films with varying content of Bi. We investigated the impact of different atomic percentages of Bi (4, 6, 8 at. %) on the properties of carrier transport and TE performance. In general, the Seebeck coefficient remained consistent across the thin films. For the 8 at. % Bi thin film, the Seebeck coefficient and electrical conductivity were measured at 230 μV/K and 730 S/cm, respectively, at room temperature. These values were more than 20 times greater than the electrical conductivity observed in the thin films with compositions of 6 and 4 at. % Bi. As a result, the Bi-Sb-Te compound exhibited a TE power factor (PF) of 38x10−4 W/mK2 at 40 °C, surpassing the PFs observed in previous compositions. The analysis of surface microstructure, combined with atomic force microscopy and Kelvin probe microscopy images, revealed that the transport of carriers in films with high Bi content was impeded by the size of particles and scattering sites. On the other hand, an augmentation in Bi content promoted the transfer of charge through crystalline regions, hence improving the mobility of carriers and the total electrical conductivity. The aforementioned results emphasize the significant influence of Bi content on the electrical properties of semiconductors and demonstrate the effectiveness of compositional engineering based on Bi content in the development of TE materials with superior performance. The present study investigates the influence of Bi content on the electrical properties of Bi-Sb-Te thin films, demonstrating that compositional adjustments based on Bi content can impact the performance of TE materials. These findings contribute to the understanding of material optimization in the field of TE.
AtıfScopus4WoS5OpenAlex5
İncele - MakaleAçık Erişim2024Scopus SJRQ1Integrating chemical analysis with in vitro, in silico, and network pharmacology to discover potential functional compounds from Marrubium astracanicum subsp. macrodon
Avşar, Ömer Kaan; Kasbolat, Sevgi; Ak, Gunes; Nilofar; Caprioli, Giovanni; Santanatoglia, Agnese; Uysal, Ahmet; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Paksoy, Mehmet Yavuz
The members of the genus Marrubium are of great interest because they contain biologically active compounds. With in this mind, we aimed to examine the chemical profiles and biological activities (antioxidant, enzyme inhibition and antimicrobial effects) of different extracts of Marrubium astracanicum subsp. macrodon. Extractions of the plants were carried out with the solvent n-hexane, acetone, acetone/water (70 %), and water. The antioxidant activity of these extracts was evaluated through six different assays, namely 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), cupric reducing antioxidant capacity (CUPRAC), ferric reducing antioxidant power (FRAP), metal chelating ability (MCA), and phosphomolybdenum (PBD). Additionally, the inhibitory effects of these solvents on five enzymes acetylcholinesterase (AChE), butyrylcholinesterase (BChE), tyrosinase, amylase, and glucosidase were investigated. The study detected 38 compounds in a plant, with the highest content in acetone and acetone/water extracts. The acetone/water extract demonstrated the highest antioxidant activity aligning with its superior total phenolic (51.9 mg gallic acid equivalent (GAE)/g) and flavonoid (31.0 mg rutin equivalent (RE)/g) content, highlighting a direct correlation between bioactive compound concentration and antioxidant potential across various assays. Regarding the enzyme inhibition activity, the acetone/water extract of this plant exhibited significant AChE inhibition measuring 2.5 mg galantamine equivalent (GALAE)/g and anti-glucosidase activity measuring 1.2 mmol acarbose equivalent (ACAE)/g. In antimicrobial evaluation, the acetone extract exhibited good antimicrobial activity against B. cereus at 0.2 mg/ml dose. In molecular docking analysis, delphinidin 3,5 diglucoside showed a good interaction with the active site of AChE active. Through the application of network pharmacology, an in-depth exploration was conducted to unravel the potential of compounds from M. astracanicum against Alzheimer's disease. The study specifically focused on identifying key targets within the Alzheimer's disease pathway, pinpointing crucial proteins such as Glycogen synthase kinase-3 (GSK3), Prostaglandin-endoperoxide synthase 2 (PTGS2), and Alzheimer's-associated amyloid precursor protein (APP). In summary, the plant can serve as a valuable ingredient in the production of functional products within the pharmaceutical, nutraceutical, and cosmeceutical applications.
AtıfScopus4OpenAlex4İncele - MakaleAçık Erişim2024Scopus SJRQ2Cytotoxic, antioxidant, and enzyme inhibitory activities of Centaurea stapfiana extracts and their HPLC-ESI-QTOF-MS profiles: Insights into an unexplored Centaurea species
Zengin, Gokhan; Fernández-Ochoa, Álvaro; de la Luz Cádiz-Gurrea, María; Jiménez, Francisco-Javier Leyva; Uba, Abdullahi Ibrahim; Ak, Gunes; Soomro, Sanam Iram; Balos, Maruf; Cakilcioglu, Ugur; Rodrigues, Maria João
The members of the genus Centaurea have a great interest in pharmaceutical and nutraceutical fields due to their biological potential. Based on this information, we aimed to evaluate the biological properties (antioxidant, enzyme inhibition and cytotoxicity) and chemical profile of the extract of Centaurea stapfiana, an unstudied species. The highest total phenolic content was found in the ethanol/water extract with 32.17 mg GAE/g. A total of 102 of them were identified by HPLC-ESI-QTOF-MS analysis. These compounds were mainly hydroxybenzoic acid and hydroxycinnamic acid as well as flavonoids. In the antioxidant tests, the ethanol/water extract had the best free radical scavenging and reducing ability. However, in the enzyme inhibition test, the ethanol extract was the most active. The extracts were also tested on two tumour cell lines (RAW 264.7 and HepG2) and one non-tumour cell line (S17). The ethanol extract showed the promising effect on HepG2 (cell viability: 28.6 % at 50 g/ml). Furthermore, we examined the interactions between the compounds and enzymatic and cellular targets. A good interaction was found between quercetin-3-xylosyl-(1- > 6)-glucoside and iNOS. In summary, our results suggest that C. stapfiana can be considered as a versatile raw material for the development of health-promoting applications in the pharmaceutical and cosmeceutical fields.
AtıfScopus13OpenAlex14
İncele - MakaleAçık Erişim2024Scopus SJRQ2The Behavior of Ceramic Fiber Geopolymer Concrete under the Effect of High Temperature
Dalğıç, Aras; Yılmazer Polat, Berivan
Geopolymer concrete (GC), also known as green concrete, contains slag, silica fume, and fly ash as binders. The absence of cement in concrete is critical to protect the world from the environmental impacts of cement production. In addition, exposure to high temperatures is a critical parameter that causes loss of strength in concrete. In this study, Geopolymer concrete samples were prepared with 10 different samples containing different proportions of slag, silica fume, and porous ash and subjected to various physical, mechanical, and optical tests. The sample (GS90) with optimum workability and compressive strength, which also showed high performance in water absorption, freeze-thaw, and UPV tests, was used in high-temperature tests. Portland cement concrete (PCC) was used as a control sample. This study investigated the effect of high temperatures on the physical and mechanical properties of fiber-free GCs containing 2%, 5%, and 10% by volume of ceramic fibers. Therefore, fiber-reinforced, fiber-free, and PCC specimens were subjected to high-temperature tests at 100, 300, 600, and 900 °C. As a result of the observation of crack growth, color changes, and compressive strength parameters in the samples subjected to high-temperature tests, the thermal resistance of the 10% ceramic fiber geopolymer concrete sample was 2.5% higher than other samples. There is no study in the literature that examines the behavior of ceramic fiber-reinforced geopolymer concrete at high temperatures. This research revealed an important finding by proving that ceramic fiber reinforcement increases the compressive strength of geopolymer concretes at a remarkable rate after high-temperature impact.
AtıfScopus8WoS10OpenAlex8İncele - DüzeltmeAçık Erişim2024Scopus SJRQ2Correction to: Detection of hateful twitter users with graph convolutional network model (Earth Science Informatics, (2023), 16, 1, (329-343), 10.1007/s12145-023-00940-w)
Utku, Anıl; Can, Umit; Aslan, Serpil
In this article the affiliation details for Serpil Aslan were incorrectly given as ‘Software Engineering Department, Turgut Üzal University, 44210 Malatya, Turkey’ but should have been ‘Department of Software Engineering, Faculty of Engineering and Natural Sciences, Malatya Turgut Ozal University, Malatya, Turkey.’ The original article has been corrected.
AtıfScopus1OpenAlex2İncele - MakaleAçık Erişim2025Scopus SJRQ4INVESTIGATING AND PLANNING ECOTOURISM AREA FOCUSED ON FOREST VILLAGERS VIA THE ANALYTICAL HIERARCHY PROCESS
ESER, Nazlı; BİLİCİ, Ebru
Ecotourism has emerged as an alternative form of tourism that brings together urban dwellers and forest villagers, while also promoting the sustainability of forest resources. This study aimed to identify the key factors influencing ecotourism in forest villages and to determine the most suitable areas based on these factors. Giresun province served as the study area, where we collected data through interviews with stakeholders and industry professionals. The collected data were analysed using the SPSS23 program and the AHP analysis, which resulted in the identification of influential factors and the mapping of suitable ecotourism areas using ArcGIS 10.8. As a result of the Kolmogorov-Smirnov and Shapiro-Wilk tests, it was observed that the data showed a normal distribution and there was a significant relationship between the variables (p > 0,05). The findings from the interviews revealed that ecotourism can serve as a significant source of income and be pursued as a full-time occupation. Furthermore, it was determined that 50 forest villages in Giresun are situated within the most suitable ecotourism area. Based on the comprehensive analyses conducted, this study will establish an economically viable access road to the forest village, facilitating optimal land-use planning in the designated areas.
- MakaleAçık Erişim2025Scopus SJRQ2Ultrasonic-assisted high-speed micro-milling of Ti6Al4V
Mahmat, Aybars; Agar, Salih; Tosun, Nihat
In this study, the effects of different cooling techniques and process parameters on the performance characteristics of ultrasonic and conventional micro-milling (1-micron fixed amplitude, 20 and 30 kHz frequencies) of Ti6Al4V alloy were experimentally investigated. The impact of independent factors on tool life, cutting force, surface topography, surface roughness and cutting temperature was determined in order to find out machinability characteristics in this paper. Machining operations were performed under 20,000, 40,000 and 60,000 rpm revolution speed. The cutting depth and feed rate of the machining were kept fixed at 0.02 mm and 0.66 mm/s, respectively. Uncoated carbide and TiSiN-coated carbide cutting tools were used in machining operations. Dry machining and two different minimum quantity of lubrication (MQL) methods were used as cooling methods. According to the results achieved in the existing study, the ultrasonic micro-milling improved the surface roughness, reduced cutting forces, cutting zone temperature, and cutting tool wear. It was also found that MQL methods among other methods used in the present study have a greater effect on performance characteristics. As the spindle speed increased, the workpiece surface roughness, cutting force and tool life decreased, while the cutting zone temperature increased.
AtıfScopus4WoS4OpenAlex4İncele - MakaleAçık Erişim2023Scopus SJRQ1Numerical study for battery thermal management system improvement with air channel in electric vehicles
Tuğan, Volkan; Yardımcı, Uğurcan
In order to ensure the safe and efficient operation of the battery system in electric vehicles, the heat generated in the batteries must be rapidly removed from the system. Therefore, a battery thermal management system is needed to ensure that the battery pack operates at appropriate temperatures. This study focuses on improving the battery thermal management system in electric vehicles. For this purpose, two different types of battery modules with new air channel design were created. The temperature distribution, maximum temperature difference and pressure drop in the battery modules were numerically investigated with computational fluid dynamics. In addition, the effect of three different air velocities (1 m/s, 2 m/s and 3 m/s) on the battery temperature was evaluated. The results showed that the maximum temperature and maximum temperature difference in the battery decreased with the increase of the air inlet velocity. It was observed that the maximum temperature difference obtained for design 2 and design 3 decreased in the range of 15.01–17.93 % and 7.25–12.22 %, respectively, compared to Design 1.
AtıfScopus34WoS35İncele - MakaleAçık Erişim2025Scopus SJRQ2Evaluation of poly(lactic acid) films incorporated with lemon peel extract oil for food packaging materials
Ertekin, Özlem
The effects of Citrus lemon peel extract oil (CLPEO) at different ratios (0%, 0.5%, 1.0% and 2.0%) on poly lactic acid blend films were evaluated concerning some properties of the films in this study. The antimicrobial effect of these films was determined against Escherichia coli, Enterococcus faecalis, Salmonella typhimurium, Bacillus cereus and Staphylococcus aureus according to the parallel stick method. Antioxidant properties of Citrus lemon peel extract oil were investigated using DPPH (2,2-diphenyl-1-picrylhydrazyl) and TEAC (trolox equivalent antioxidant capacity) method. The inhibition of DPPH for Citrus lemon peel extract oil was found to be as (84%), (76%), (71%), and (62%) for CLPEO, PLA2, PLA1, PLA0.5, respectively. Antibacterial effect was detected at CLPEO and PLA2 films, with CLPEO being important as an environmentally friendly packaging material in terms of antibacterial, antioxidant activity, FT-IR, SEM, WVP, opacity and mechanical properties.
- MakaleAçık Erişim2024Scopus SJRQ4Erythropoietin and Hypericum perforatum ameliorate Gentamicin–induced nephrotoxicity in rats; [La eritropoyetina y el Hypericum perforatum mejoran la nefrotoxicidad inducida por gentamicina en ratas]
Ak, Tuba Parlak; Sağıroğlu, Meltem; Korkmaz, Gizem Elif; Yaman, Mine
Gentamicin (GM), which causes nephrotoxicity, is an aminoglycoside antibiotic commonly prescribed to treat of gram–negative infections. Erythropoietin (EPO), which has several biological functions including neuroprotection, wound healing and nephroprotection, is a glycoprotein hormone that controls erythropoiesis. Hypericum perforatum (HP) is a medicinal herb with antibacterial and nephroprotective effects. The aim of this study is to demonstrate the efficacy of EPO and HP in GM nephrotoxicity using combined biochemical, histopathological and immunohistochemical evaluations together. A total of 36 male Spraque–Dawley rats were divided into as control, GM (100 mg·kg-1 day), GM+EPO, GM+HP, EPO (1000 IU·kg-1 three consecutive days apart) and HP (200 mg·kg-1 day) groups (n=6) and the experiment lasted for 9 days. GM–induced increased relative kidney weight and increased serum urea nitrogen (BUN), creatinine and urea levels were reduced by EPO and HP. EPO and HP reduced the level of malondialdehyde (MDA), which increased with GM application, and increased the activities of reduced glutathione (GSH), glutathione peroxidase (GSH–Px), and catalase (CAT). GM nephrotoxicity resulted in tubular degeneration, vacuolization and hyaline deposits, glomerular degeneration and interstitial mononuclear cell infiltration. EPO and HP attenuated these histopathological changes. Also, EPO and HP also reduced caspase–3 immunoreactivities, which increased with GM application. It was shown that EPO and HP have attenuating effects on GM–induced kidney injury, and especially the intense antioxidant content of HP has a regulatory effect on the negative consequences of oxidative stress.
- MakaleAçık Erişim2023Scopus SJRQ2ResMIBCU-Net: an encoder–decoder network with residual blocks, modified inverted residual block, and bi-directional ConvLSTM for impacted tooth segmentation in panoramic X-ray images
Imak, Andaç; Çelebi, Adalet; Polat, Onur; Türkoğlu, Muammer; Şengür, Abdulkadir
Objective: Impacted tooth is a common problem that can occur at any age, causing tooth decay, root resorption, and pain in the later stages. In recent years, major advances have been made in medical imaging segmentation using deep convolutional neural network-based networks. In this study, we report on the development of an artificial intelligence system for the automatic identification of impacted tooth from panoramic dental X-ray images. Methods: Among existing networks, in medical imaging segmentation, U-Net architectures are widely implemented. In this article, for dental X-ray image segmentation, blocks and convolutional block structures using inverted residual blocks are upgraded by taking advantage of U-Net’s network capacity-intensive connections. At the same time, we propose a method for jumping connections in which bi-directional convolution long short-term memory is used instead of a simple connection. Assessment of the proposed artificial intelligence model performance was evaluated with accuracy, F1-score, intersection over union, and recall. Results: In the proposed method, experimental results are obtained with 99.82% accuracy, 91.59% F1-score, 84.48% intersection over union, and 90.71% recall. Conclusion: Our findings show that our artificial intelligence system could help with future diagnostic support in clinical practice.
AtıfScopus21OpenAlex23İncele - MakaleAçık Erişim2025Scopus SJRQ3Optimization of rare earth elements recovery from Kızıldag (Karaman-Türkiye) shale ore using response surface methodology
Uysal, Turan; Ünal, Ceren Erust; Akça, Muhammet Esat; Sis, Hikmet; Erdemoğlu, Murat
In this study, the usability of bauxite-related shale ore, rich in Rare Earth Elements (REEs), to produce REEs, which have high added value and critical importance, was investigated. In this context, Kızıldag (Karaman-Türkiye) shale ore, was prepared for tests through size reduction and sampling processes. HCl leaching was performed at different acid concentrations, leaching times, leaching temperatures, and liquid/solid ratios to determine the optimum leaching conditions for the milled ore. The modeling and optimization parameters related to leaching recovery were investigated using the response surface method (RSM). The results were evaluated using analysis of variance, three-dimensional graphs were drawn, and the accuracy of the models was discussed. Accordingly, optimum values were found, and the REE leaching recovery corresponding to these optimum values was 49.13%. It was concluded that the optimization results were compatible with the experimental results, and the average error rate (6.35%) was low.
AtıfScopus3OpenAlex4İncele - MakaleYalnız künye2023Scopus SJRQ2Numerical investigation of the effect of using louver baffles on thermal performance in solar air collectors
Tuğan, Volkan; Işık, Erdem
Conventional flat plate solar air collectors have advantages such as low cost and simple design. However, their thermal efficiency is lower than that of other designs. The thermal efficiency of these collectors can be increased by detailed examination of parameters such as the shape, size, arrangement and material of the air duct. In this study, it is aimed to improve the thermal efficiency of solar air collectors. The effect of louver baffles, which were not previously used in solar air collectors, on thermal efficiency was investigated numerically via computational fluid dynamics. Three different solar air collectors with flat plates, segmented baffles, and louver baffles were compared in terms of thermal efficiency. In addition, pressure drops in solar air collectors were investigated. The mass flow rate of the air in all collectors is assumed to be 0.04 kg/s. Analyzes were carried out between 09:00 and 16:00. The thermal efficiency values obtained during the day for solar air collectors with flat plate, segmented baffles and louver baffles are 27.66%–56.35%, 29.57%–58.82% and 30.09%–59.47%, respectively. The daily thermal efficiency values obtained for solar air collectors with flat plate, segmented baffles and louver baffles are 46.98%, 49.18% and 49.87%, respectively. The pressure drop for solar air collectors with flat plate, segmented baffles and louver baffles were found to be 4.62, 18.82 and 5.96 Pa, respectively. Based on the data obtained from this study, louver baffles are recommended for use in solar heating applications due to their high thermal efficiency and low pressure drop.
AtıfScopus5WoS5OpenAlex5İncele - MakaleYayıncıda açık erişim2023Scopus SJRQ1Soil-dependent β and γ shape parameters of the Haverkamp infiltration model for 3D infiltration flow
Yilmaz, D.; Lassabatere, L.; Moret-Fernandez, D.; Rahmati, M.; Angulo-Jaramillo, R.; Latorre, B.
Estimating of soil sorptivity ((Figure presented.)) and saturated hydraulic conductivity ((Figure presented.)) parameters by field infiltration tests are widespread due to the ease of the experimental protocol and data treatment. The analytical equation proposed by Haverkamp et al. (1994) allows the modelling of the cumulative infiltration process, from which the hydraulic parameters can be estimated. This model depends on both initial and final values of the soil hydraulic conductivity, initial soil sorptivity, the volumetric water content increase ((Figure presented.)) and two infiltration constants, the so-called (Figure presented.) and (Figure presented.) parameters. However, to reduce the number of unknown variables when inverting experimental data, constant parameters such as (Figure presented.) and (Figure presented.) are usually prefixed to 0.6 and 0.75, respectively. In this study, the values of these constants are investigated using numerical infiltration curves for different soil types and initial soil water contents for the van Genuchten-Mualem (vGM) soil hydraulic model. Our new approach considers the long-time expansions of the Haverkamp model, the exact soil properties such as (Figure presented.), (Figure presented.) and initial soil moisture to derive the value of the (Figure presented.) and (Figure presented.) parameters for each specific case. We then generated numerically cumulative infiltration curves using Hydrus-3D software and fitted the long-time expansions to derive the value of the (Figure presented.) and (Figure presented.) parameters. The results show that these parameters are influenced by the initial soil water content and the soil type. However, for initially dry soil conditions, some prefixed values can be proposed instead of the currently used values. If an accurate estimate of (Figure presented.) and (Figure presented.) is the case, then for coarse-textured soils such as sand and loamy sand, we propose the use of 0.9 for both constants. For the remaining soils, the value of 0.75 can be retained for (Figure presented.). For (Figure presented.) constant, 0.75 and 1.5 values can be considered for, intermediate permeable soils (sandy loam and loam) and low permeable soils (silty loam and silt), respectively. We clarify that the results are based on using the vGM model to describe the hydraulic functions of the soil and that the results may differ, and the assumptions may change for other models.
AtıfScopus12OpenAlex10İncele - MakaleYalnız künye2023Scopus SJRQ1An efficient hybrid weather prediction model based on deep learning
Utku, A.; Can, U.
Weather events directly affect human activities. In particular, extreme weather events with global warming, forest fires, and high air temperatures that cause drought make human life difficult. Effective and accurate weather prediction models are needed to take precautions against such climatic events. Therefore, it is essential to develop models that make precise weather predictions. Technological developments contributed significantly to developing successful deep learning-based weather prediction models. With a high success rate, this study proposed a hybrid weather prediction model based on Convolutional Neural Networks and Recurrent Neural Networks models. The proposed hybrid model was applied to the Jena dataset, which contains 14-parameter, large-scale meteorological data that were never utilized for weather prediction. The experimental results were compared with popular deep learning, machine learning, and statistical methods such as Auto-Regressive Integrated Moving Average, Convolution Neural Networks, Long-Short Term Memory, Multilayer Perceptron, Random Forest, Recurrent Neural Networks, and Support Vector Machine. As a result of these comparisons, the proposed hybrid model obtained the best prediction result for all metrics. For example, according to the weather prediction results for Jena, Germany, the proposed hybrid model got the results of Mean Squared Error: 0.035, Root-Mean-Squared Error: 0.189, Mean Absolute Error: 0.126, and R-Squared: 0.987.
AtıfScopus15WoS11OpenAlex11İncele - MakaleAçık Erişim2024Scopus SJRQ2Combining chemical profiles and biological abilities of different extracts from Tanacetum nitens (Boiss. & Noë) Grierson using network pharmacology
Dall'Acqua, Stefano; Yagi, Sakina; Sut, Stefania; Uba, Abdullahi Ibrahim; Ponniya, Sathish Kumar M.; Koyuncu, Ismail; Toprak, Kenan; Balos, Mehmet Maruf; Kaplan, Alevcan; Çakılcıoğlu, Uğur
Tanacetum nitens (Boiss. & Noë) Grierson is an aromatic perennial herb used in Turkish traditional medicine to treat headache, fever, and skin diseases. This study aimed to investigate the chemical composition, antioxidant, enzyme inhibition, and cytotoxic properties of T. nitens aerial parts. Organic solvent extracts were prepared by sequential maceration in hexane, dichloromethane, ethyl acetate, and methanol while aqueous extracts were obtained by maceration or infusion. Nuclear magnetic resonance (NMR) and LC-DAD-MS analysis allowed the identification and quantification of different phytoconstituents including parthenolide, tanacetol B, tatridin B, quinic acid derivatives, β-sitosterol, and glycoside derivatives of quercetin and luteolin. The type and amount of these phytochemicals recovered by each solvent were variable and significant enough to impact the biological activities of the plant. Methanolic and aqueous extracts displayed the highest scavenging and ions-reducing properties while the dichloromethane and ethyl acetate extracts exerted the best total antioxidant activity and metal chelating power. Results of enzyme inhibition activity showed that the hexane, ethyl acetate, and dichloromethane extracts had comparable anti-acetylcholinesterase activity and the latter extract revealed the highest anti-butyrylcholinesterase activity. The best α-amylase and α-glucosidase inhibition activities were obtained from the hexane extract. The dichloromethane and ethyl acetate extracts exhibited the highest cytotoxic effect against the prostate carcinoma DU-145 cells. In conclusion, these findings indicated that T. nitens can be a promising source of biomolecules with potential therapeutic applications.
AtıfScopus7OpenAlex7İncele - DüzeltmeYalnız künye2024Scopus SJRQ1Retraction notice to “The influence of battery distance on a hybrid air-cooled cylindrical lithium-ion battery phase change material thermal management system for storing solar energy” [Journal of Energy Storage 52, Part B (2022) 104873] (Journal of Energy Storage (2022) 52(PB), (S2352152X22008805), (10.1016/j.est.2022.104873))
Akkurt, Nevzat; Aghakhani, S.; Mahmoud, Mustafa Z.; Tag El Din, ElSayed M.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal). Please note that an Expression of Concern has previously been published to alert readers to an ongoing investigation into this paper. This retraction supersedes the Expression of Concern. This article has been retracted at the request of the editor. In investigating concerns brought up regarding the authenticity of the article, the editor reached out to the authors for an explanation. Furthermore, the editor discovered suspicious changes in authorship between the original submission and the revised version of this paper. In summary, the author names Nevzat Akkurt, Mustafa Z. Mahmoud and ElSayed M. Tag El Din were added to the revised paper without explanation and without exceptional approval by the editor, which is contrary to the journal policy on changes to authorship. The authors failed to provide a satisfactory explanation to the above points. The editor therefore feels that the findings of the manuscript cannot be relied upon and that the article needs to be retracted.
- DüzeltmeAçık Erişim2024Scopus SJRQ1Correction to: A Novel Secure S-box Design Methodology Based on FPGA and SHA-256 Hash Algorithm for Block Cipher Algorithms (Arabian Journal for Science and Engineering, (2024), 10.1007/s13369-024-09251-8)
Aydin, Yilmaz; Garipcan, Ali Murat; Özkaynak, Fatih
In the original publication, Table 1 was published with wrong values. The corrected table is given below. This has been updated in the original article. (Table presented.) 8 × 8 s-box component obtained through the proposed scheme 0 1 2 3 4 5 6 7 8 9 A B C D E F 0 7 16 40 37 222 29 204 225 65 81 156 199 63 42 44 197 1 158 2 11 117 30 134 106 209 24 78 152 141 215 251 160 36 2 249 6 228 75 233 198 132 203 147 100 176 97 214 43 239 59 3 146 47 200 49 79 195 188 201 184 85 218 151 213 154 76 253 4 17 196 26 120 105 130 45 115 186 4 224 145 118 252 138 208 5 255 10 5 129 236 91 21 162 216 109 72 27 243 207 89 13 6 124 86 206 179 192 172 235 68 28 230 74 54 99 80 139 143 7 182 234 108 149 94 168 177 3 64 250 46 41 9 191 232 136 8 84 210 88 205 23 15 95 56 50 83 107 190 98 242 103 19 9 60 169 101 181 114 174 69 82 119 112 247 244 128 51 96 1 A 123 90 150 93 32 159 57 237 170 52 231 202 125 217 155 73 B 189 31 66 14 194 62 227 104 140 165 153 131 20 12 211 245 C 111 102 183 142 137 113 187 254 133 77 116 122 161 110 38 173 D 39 18 87 148 175 121 35 193 70 229 92 55 166 219 163 171 E 185 8 126 135 127 223 240 58 53 22 248 246 167 67 48 212 F 241 144 221 178 220 34 71 0 61 164 180 157 226 238 25 33
AtıfScopus1İncele - MakaleAçık Erişim2023Scopus SJRQ1Adding New Scientific Evidences on the Pharmaceutical Properties of Pelargonium quercetorum Agnew Extracts by Using In Vitro and In Silico Approaches
Chiavaroli, Annalisa; Libero, Maria Loreta; Di Simone, Simonetta Cristina; Acquaviva, Alessandra; Nilofar; Recinella, Lucia; Leone, Sheila; Brunetti, Luigi; Cicia, Donatella; Izzo, Angelo Antonio
Pelargonium quercetorum is a medicinal plant traditionally used for treating intestinal worms. In the present study, the chemical composition and bio-pharmacological properties of P. quercetorum extracts were investigated. Enzyme inhibition and scavenging/reducing properties of water, methanol, and ethyl acetate extracts were assayed. The extracts were also studied in an ex vivo experimental model of colon inflammation, and in this context the gene expression of cyclooxygenase-2 (COX-2) and tumor necrosis factor α (TNFα) were assayed. Additionally, in colon cancer HCT116 cells, the gene expression of transient receptor potential cation channel subfamily M (melastatin) member 8 (TRPM8), possibly involved in colon carcinogenesis, was conducted as well. The extracts showed a different qualitative and quantitative content of phytochemicals, with water and methanol extracts being richer in total phenols and flavonoids, among which are flavonol glycosides and hydroxycinnamic acids. This could explain, at least in part, the higher antioxidant effects shown by methanol and water extracts, compared with ethyl acetate extract. By contrast, the ethyl acetate was more effective as cytotoxic agent against colon cancer cells, and this could be related, albeit partially, to the content of thymol and to its putative ability to downregulate TRPM8 gene expression. Additionally, the ethyl acetate extract was effective in inhibiting the gene expression of COX-2 and TNFα in isolated colon tissue exposed to LPS. Overall, the present results support future studies for investigating protective effects against gut inflammatory diseases.
AtıfScopus35OpenAlex35İncele - MakaleYayıncıda açık erişim2025Scopus SJRQ2Effect of pre-freezing on motility, viability and abnormality of Nile tilapia fish Oreochromis niloticus sperm post cryopreservation
Muchlisin, Z.A.; Hasibuan, R.R.; Maulida, S.; Eriani, K.; Fadli, N.; Muhammadar, A.A.; Handayani, L.S.; Suharman, I.; Kocabas, M.; Kocabas, F.K.
Nile tilapia Oreochromis niloticus is a popular freshwater fish that has been extensively and intensively cultured worldwide. However, cryopreservation of its sperm, especially pre-freezing procedure, has not been properly developed. Therefore, the study aimed to determine the best pre-freezing procedure for cryopreservation of Nile tilapia Oreochromis niloticus sperm. The completely randomized design with five treatments and four replications was employed in this study. The tested treatments were T1=4°C → 0°C →-4°C →-10°C →-79°C →-196°C, T2=4°C→ 0°C →-4°C →-10°C →-196°C, T3=4°C → 0°C →-4°C →-196°C, T4=4°C → 0°C →-196°C), and T5=4°C →-196°C, with a 10 min equilibration at each respective temperature. Furthermore, sperm was cryopreserved for two weeks in liquid nitrogen (-179oC). The results of the ANOVA test showed that pre-freezing had a significant effect on sperm motility, and viability (P<0.05), but had no considerable impact on sperm abnormality (P>0.05). Treatment T4 exhibited higher motility and viability, but these values were not significantly different from T3 and T5. Based on practical consideration, it was recommended to utilize the T5 pre-freezing procedures (4°C →-196°C) for cryopreservation of Nile tilapia sperm. Considering these results, Nile tilapia sperm can be directly cryopreserved into liquid nitrogen after equilibration at 4°C for 10 min.
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