The effect and characterization of newly synthesized SrBr2 reinforced bone grafts on structure and cell viability

Abstract: In this study, a highly durable SrBr2 compound was added to Ca(NO3)2·4H2O, KOH, NaNO3, P2O5, and urea (CO(NH2)2) compounds at different ratios (wt 10–30%); biografts were synthesized in different compositions using the sol gel method They were characterized using X-ray diffraction, Fourier transform infrared spectrometer, scanning electron microscope, and mechanical tests e.g. hardness and compression. Structural, mechanical properties and cell viabilities of the synthesized biografts were comparatively examined. Fourier transform infrared spectrometer and X-ray diffraction analysis results showed that, including SrBr2, hydroxyapatite had formed in the biografts. Also, hardness and compression tests revealed that compressive stress and hardness values of the grafts increased as the amount of SrBr2 increased. The cell viability ratios also enhanced with the amount of SrBr2 increased in the synthesized biografts. Graphical Abstract: [InlineMediaObject not available: see fulltext.]