Sürdürülebilir Kalkınma Amaçları

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• MakaleYalnız künye2026Scopus SJRQ3/r/munzur/1434
  The relationship between muscle strength and oxygenation and activities of daily living in adolescents and young adults with pulmonary arterial hypertension

  Dik, Jan; Topcuoglu, Ceyhun; Vardar-Yagli, Naciye; Goksuluk, Merve Basol; Aypar, Ebru; Alehan, Dursun; Saglam, Melda

  Pulmonary arterial hypertension leads to dyspnoea, fatigue, and oxygen desaturation, limiting activities of daily living and functional capacity. This study aimed to evaluate the impact of pulmonary arterial hypertension on activities of daily living performance, functional capacity, peripheral muscle strength, oxygen dynamics, and energy expenditure. Eighteen adolescents and young adults with pulmonary arterial hypertension (10 females, 8 males; age 9–30 years) and 15 healthy controls (10 males, 5 females; age 9–30 years) were included. Peripheral muscle strength was assessed using a handheld dynamometer, functional capacity via the 6-minute walk test, and muscle oxygenation through near-infrared spectroscopy. Lower-limb endurance was evaluated with the 1-minute sit-to-stand test and activities of daily living performance with the Glittre Activities of Daily Living test. Compared to controls, the pulmonary arterial hypertension group had significantly lower 6-minute walk test distance (441.9 m versus 636.9 m; p < 0.001), reduced sit-to-stand repetitions (28 versus 42.1; p < 0.001), weaker peripheral strength, and lower minimum muscle oxygen saturation (24.9% versus 51.8%; p < 0.001). Glittre Activities of Daily Living test duration was longer (143 s versus 105 s; p < 0.001), with greater oxygen desaturation (−13% versus −1%; p < 0.001), higher dyspnoea scores using modified Borg scale (5 versus 1; p < 0.001), and blunted heart rate response (ΔHR [change in heart rate]: 32 versus 64; p = 0.011). These findings demonstrate that pulmonary arterial hypertension significantly impairs both cardiopulmonary and peripheral muscle function. Protecting muscle health and improving functional capacity should be prioritised to enhance quality of life in this population.

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• MakaleYalnız künye2026Scopus SJRQ1/r/munzur/1307
  Psychological well-being and aggression in handball players: examining the mediating role of exercise addiction

  Güler, Muhammed; Yeşiltepe, Akgün; Topcuoğlu, Ceyhun

  Objective: This study aimed to examine the relationship between psychological well-being and aggression among handball players and to determine whether exercise addiction mediates this relationship. Methods: A descriptive, cross-sectional, and correlational design was used. The population consisted of players competing in the Turkish Handball Leagues during the 2024–2025 season, and 442 athletes participated using a non-probability sampling method. Data were collected via an online survey including a personal information form, the Psychological Well-Being Scale, the Buss–Perry Aggression Questionnaire, and the Exercise Addiction Inventory. Results: Psychological well-being showed a significant negative correlation with aggression (r = −0.242, p < 0.001). Exercise addiction was positively associated with both psychological well-being (r = 0.212, p < 0.001) and aggression (r = 0.105, p = 0.027). Mediation analysis indicated that exercise addiction significantly and partially mediated the relationship between psychological well-being and aggression (indirect effect 95% CI: 0.0246–0.1654). The direct effect of psychological well-being on aggression remained significant (β = −0.7093, p < 0.001). Conclusion: Higher psychological well-being was associated with lower aggression among handball players, whereas exercise addiction was associated with both higher psychological well-being and higher aggression and emerged as a partial statistical mediator of this relationship. These findings may help inform future studies and preventive strategies focusing on athlete mental health and behavioral regulation. However, because of the cross-sectional design, causal inferences cannot be drawn.

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• MakaleAçık Erişim2026Scopus SJRQ2/r/munzur/1300
  Reliability and validity of the Turkish version of the pain attention and awareness questionnaire for nonspecific musculoskeletal pain

  Sürmeli, Mahmut; Özdemir, Özlem Çinar; Topcuoğlu, Ceyhun

  Background: Reliable and valid assessments of pain vigilance and awareness are crucial for understanding and treating pain within cognitive-behavioral frameworks, such as the fear-Avoidance Model. While the Pain Vigilance and Awareness Questionnaire (PVAQ) is a widely used tool for this purpose, no culturally adapted and validated version exists for the Turkish-speaking population, creating an instrumental and clinical gap. Objective: This study aimed to translate, culturally adapt, and comprehensively evaluate the psychometric properties of the Turkish version of the PVAQ in a sample of patients with nonspecific musculoskeletal pain. Methods: An instrumental, cross-sectional study was conducted. The PVAQ was translated and adapted into Turkish according to established guidelines. A sample of 131 patients with low back, neck, or shoulder pain completed the PVAQ-T, the Pain Catastrophizing Scale (PCS), the Tampa Scale for Kinesiophobia (TSK), the Hospital Anxiety and Depression Scale (HADS), and a visual analog scale (VAS) for pain intensity. Reliability was assessed via internal consistency (Cronbach’s alpha) and test-retest reliability (intraclass correlation coefficient - ICC). Construct validity was examined via exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). Criterion validity was evaluated through Pearson correlations with the PCS, TSK, and HADS. Results: The PVAQ-T demonstrated acceptable internal consistency (Cronbach’s α = 0.83) and good test-retest reliability (ICC = 0.918). EFA supported a two-factor structure (vigilance and awareness), explaining 62.3% of the variance. CFA indicated that the original 16-item model had a suboptimal fit (CFI = 0.807; GFI = 0.732; SRMR = 0.060; RMSEA = 0.138, and χ²/df = 3.46). Following the removal of items 4 and 12 based on exploratory and item-level findings, some fit indices showed modest improvement (CFI = 0.836; GFI = 0.768; SRMR = 0.006), whereas others remained unchanged or worsened (RMSEA = 0.144; χ²/df = 3.69). The PVAQ-T total score showed moderately to strongly, statistically significant (p < 0.001) correlations with the PCS (r = 0.681), TSK (r = 0.694), HADS-Anxiety (r = 0.491), and HADS-Depression (r = 0.416) scores, supporting its criterion validity. Conclusion: Within a Turkish sample of individuals with nonspecific musculoskeletal pain, the 14-item Turkish version of the PVAQ demonstrates adequate reliability and validity for assessing pain-related attention and awareness. While the two-factor structure was supported at the exploratory level, confirmatory findings suggest that results should be interpreted with caution. The PVAQ-TR may be a useful instrument for research and clinical assessment of pain-related attentional processes, highlighting the importance of cultural adaptation and empirical evaluation of psychometric instruments.

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• MakaleYalnız künye2026Scopus SJRQ2/r/munzur/596
  Postural control impairment in chronic obstructive pulmonary disease (COPD): The role of respiratory muscle weakness and spinal curvature

  Topcuoğlu, Ceyhun; Ozel, Alp; Tutun Yumin, Eylem; Sertel, Meral; Tug, Tuncer

  BACKGROUND: Chronic obstructive pulmonary disease (COPD) is associated with respiratory muscle dysfunction, postural alterations and balance impairment. However, the impact of respiratory muscle weakness on postural control and its relationship with spinal curvature and mobility remain insufficiently clarified. OBJECTIVES: The objectives of this study were to compare postural control in individuals with COPD with and without respiratory muscle weakness; to examine the relationship among spinal curvature, spinal mobility, postural control and respiratory muscle strength; and to determine the effect of respiratory muscle strength on postural control. METHODS: This cross-sectional study included 41 clinically stable individuals with COPD aged 40–75 years. Respiratory muscle strength was assessed using a mouth pressure measurement device. Postural control and balance were evaluated with the Biodex Balance System and functional tests. Higher stability index values indicate greater postural sway and poorer balance performance, whereas lower values reflect better postural stability. Spinal curvature and mobility were assessed using the Spinal Mouse®. RESULTS: Individuals with respiratory muscle weakness showed significantly higher overall, anterior–posterior and medial–lateral stability indices, as well as worse eyes-open and eyes-closed firm-surface indices compared to those without weakness (p < 0.05). In participants with severe and very severe COPD, thoracic kyphosis angle was significantly associated with MIP, MIP% and multiple balance indices under different surface and visual conditions (p < 0.05). CONCLUSIONS: Respiratory muscle weakness is associated with impaired postural control and balance performance in individuals with COPD, and thoracic spinal curvature appears to be linked to both respiratory muscle strength and balance outcomes.

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• BildiriYalnız künye2025Scopus SJRQ1/r/munzur/4949
  Perceived learning after manual airway clearance techniques practice: peer learning vs. simulation-based learning

  Cakmak-Onal, Aslihan; Aksel-Uylar, Aydan Asli; Saglam, Melda; Topcuoglu, Ceyhun; Vardar-Yagli, Naciye; Calik-Kutukcu, Ebru; Demirel, Aynur; Inal-Ince, Deniz

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• MakaleYalnız künye2025Scopus SJRQ1/r/munzur/4472
  Relationship between distance-saturation product of the 6-minute walk test and respiratory and peripheral muscle strength in renal transplant patients

  Firat, Merve; Topcuoglu, Ceyhun; Aksel-Uylar, Aydan Asli; Saglam, Melda; Erdut, Arda; Yildirim, Tolga; Vardar-Yagli, Naciye

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• MakaleAçık Erişim2025/r/munzur/6023
  A simple touch into the busy work routine: progressive relaxation and posture exercises improve physical and mental health of health professionals

  Goksuluk, Merve Basol; Tütün Yümin, Eylem; Parlak, Ebru; Topcuoglu, Ceyhun; Sürmelı, Mahmut; Hamurcu, Reşat

  Aims: The aim of this study was to implement a combination of the progressive muscle relaxation technique (PMRT) along with posture exercises and assess their impact on the mental and physical well-being of health professionals with health complaints. Methods: This quasi-experimental study utilized hybrid, remote, and web-based telehealth methods, including phone calls, video recordings, and electronic documents. Thirty-eight health professionals experiencing pain engaged in PMRT twice a day, every two days, over a two-week period. Posture exercises were seamlessly integrated into their daily work routines and performed 2-3 times a day. Various parameters, including pain, fatigue, anxiety, depression, kinesiophobia, sleep quality, and centrality of pain, were assessed both before and after the treatment. Results: Significant improvements were observed in the prevalence, intensity, and centrality of pain, accompanied by a reduction in fatigue, anxiety, and depression scores post-treatment (p<0.05). However, there was no notable improvement in kinesiophobia and sleep quality scores following the treatment (p>0.05). Conclusion: The integration of PMRT and posture exercises into the daily routines of health professionals, delivered through remote web-based telehealth, emerges as an effective and straightforward strategy for ameliorating certain physical complaints and enhancing mental health. This approach holds the potential to be easily adapted into both daily life and work environments, offering a valuable tool for coping with work-related disorders.

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• MakaleAçık Erişim2025Scopus SJRQ1/r/munzur/1128
  Effects of inspiratory muscle training on physical fitness in cystic fibrosis: a systematic review and meta-analysis

  Aksel-Uylar, Aydan Asli; Topcuoglu, Ceyhun; Saglam, Melda; Vardar-Yagli, Naciye

  Background: Cystic fibrosis (CF) is a multisystem disease primarily affecting the lungs. It impacts physical fitness due to increased bronchial secretions and exercise intolerance. Inspiratory muscle training (IMT) is recommended as a pulmonary rehabilitation approach. Therefore, we aimed to examine the effect of inspiratory muscle training on health-related physical fitness in CF. Methods: Articles were searched in five databases from inception to June 2025. All randomized controlled trials comparing IMT with a control group in individuals with cystic fibrosis were included. Four randomized controlled trials involving a total of 90 individuals with CF met the inclusion criteria. Results: A significant difference was found in the change in maximal work capacity, maximal minute ventilation, and exercise duration during the exercise test in the IMT group compared to the control group. However, no significant difference was observed in the change in maximal oxygen uptake, 6-minute walk test distance, and oxygen saturation during the 6-minute walk test between the IMT group and the control group. Conclusion: The therapeutic effectiveness of IMT for physical fitness is still uncertain. The evidence is not enough to assess how IMT can be used to enhance health-related physical fitness in CF. Further research should explore the optimal intensity and duration of IMT training needed to improve cardiorespiratory fitness. Additionally, future studies should evaluate how effective IMT is when examining its impact on health-related physical fitness.

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• MakaleYayıncıda açık erişim2023Scopus SJRQ2/r/munzur/1653
  The Symptom Experience and Functioning of Non-Hospitalized COVID-19 Patients Within the First 20 days

  Tütün Yümin, Eylem; Sürmeli, Mahmut; Topcuoğlu, Ceyhun; Başol Göksülük, Merve; Yümin, Murat

  The adverse physical, psychological, and mental health consequences associated with COVID-19 illness are well-documented. However, how specific symptoms change over time and how COVID-19 affects one’s day-to-day activities of daily living (ADL), Quality of Life (QoL), sleep quality, and fatigue severity are not well described. This longitudinal and descriptive study examined the changes in COVID-19 symptoms, ADL, QoL, sleep quality, and fatigue severity within the first 20 days. A convenience sample (n = 41) of non-hospitalized SARS-CoV-2 positive patients were recruited and followed for 20 days. Participants completed self-report measures: COVID-19 symptoms, ADL, QoL, sleep quality, and fatigue severity at days: 1, 10, and 20 following a diagnosis. Findings revealed that symptoms decreased over 20 days (p <.001). In parallel with the decrease in symptoms, QoL and ADL improved over 20 days (p <.05). However, sleep quality and fatigue severity did not improve within 20 days (p >.05). Our findings contribute to the growing evidence that COVID-19 symptoms can linger, especially fatigue and sleep quality, that affect overall day-to-day functioning for at least 20 days after diagnosis. To mitigate the effect of COVID-19 on QOL and ADL, findings underscore the need for clinicians to work collaboratively with patients to develop a symptom management plan for a variety of symptoms including fatigue and sleep quality. Beginning to repurpose existing self-management strategies for the longer term COVID-19 symptoms could be beneficial and help to optimize patient outcomes. Future work should examine these variables over a longer timeframe and among different samples of non-hospitalized patients.

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  AtıfScopus1·WoS1

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• MakaleAçık Erişim2022Scopus SJRQ3/r/munzur/2560
  Examination of diaphragm thickness, mobility and thickening fraction in individuals with COPD of different severity

  Topcuoğlu, Ceyhun; Tütün Yümin, Eylem; Hizal, Mustafa; Konuk, Suat

  Background/aim: Diaphragm thickness and mobility assessed by ultrasound in individuals with Chronic Obstructive Pulmonary Disease (COPD) reflect the function of the diaphragm. The aim of this study is to compare the diaphragm thickness, mobility, and thickening fraction in individuals with COPD of different severity and healthy individuals and examine the relationship between these parameters and pulmonary function test parameters. Materials and methods: A cross-sectional observational study design was used. Thirty individuals (mild = 11; moderate = 13; severe = 6) with COPD and 29 healthy male individuals aged between 40–75 years were included in the study. The individuals included in the study were evaluated between October 2020/May 2021. Pulmonary functions were measured with a spirometer, while diaphragm thickness, mobility, and thickening fraction were measured by ultrasound. Results: The right and left diaphragm thickness, mobility, thickness variation, thickening fraction, and mobility were lower in individuals with COPD than in healthy individuals (p < 0.05). The left Functional Residual Capacity (FRC) diaphragm thickness, right Total Lung Capacity (TLC), and FRC diaphragm thickness were higher in mild COPD than moderate COPD and moderate COPD than severe COPD (p < 0.05). The right diaphragmatic thickening fraction and rate were higher in mild COPD than in moderate and severe COPD (p < 0.05). The left mobility was lower in severe COPD than in mild COPD (p < 0.05). Conclusion: Diaphragm ultrasound parameters decrease as disease severity increases in individuals with COPD. We think that adding diaphragm ultrasound parameters together with pulmonary function test to the evaluation of individuals with COPD will provide additional contributions to determining the course of the disease.

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  AtıfScopus17·WoS17·OpenAlex17·TR Dizin1

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