Sürdürülebilir Kalkınma Amaçları
Yayınlar
- MakaleYalnız künye2025Scopus SJRQ4Bioaccumulation of copper by Gammarus pulex (L., 1758): monitoring through a statistical modelling approach
Pala, Aysegul; Ince, Muharrem; Serdar, Osman
The aim of this study is to test freshwater gammarids as ecotoxicological biomarkers. Gammarids were collected from fresh water and adapted to the laboratory environment. Then, the influence of various variables was investigated. For monitoring and detecting the bioaccumulation level in Gammarus pulex exposed to controlled copper ions and to evaluate potential human and ecological risks, the use of G. pulex as sentinel indicators of water quality is one rational approach. Copper bioaccumulation rate and fate are currently not sufficiently studied. For optimization, the experimental conditions to ensure bioaccumulation level and to find the effects of various variables on proses, a Box–Behnken experimental design was performed. Used mentioned model with statistical underpinnings for Cu2+ ions bioaccumulation have been analyzed, tested and verified and the viability of G. pulex as a biomonitor. The variables’ optimum levels (temperature; 18.1, pH; 4.3, initial concentration of Cu2+ ions, mg L−1; 11.2 and exposure time, h; 42.2) were achieved by employing the quadratic regression model. Critical role of G. pulex in freshwater biomonitoring and their potential to be evaluated as biomarkers for Cu2+ ions was confirmed. It was also explored to see if G. pulex may serve as a potential tool for estimating aquatic quality.
AtıfScopus1WoS1OpenAlex1
İncele - MakaleYalnız künye2024Scopus SJRQ2Process optimization and modeling of Pb(II) ions adsorption on a new and reusable biocomposite material using experimental design approach
Ince, Muharrem; Kaplan Ince, Olcay; Alp Kavlo, Hevidar
This research paper aimed to establish the optimal conditions for lead (Pb(II)) ions from industrial wastewater (IW) using response surface methodology and central composite design (CCD) approach. A fixed-bed column study was designed by using a novel and reusable biocomposite material, Amanita vaginata (A. vaginata) immobilized on Amberlite XAD-4 resin (A&XAD-4@AV), to find out biosorption behavior of Pb(II) ions. Various experimental variables such as optimum pH value, biocomposite material amount, flow rate, and Pb(II) ions initial concentration were investigated, which significantly affected the Pb(II) ions removal efficiency. The maximum Pb(II) removal efficiency of A&XAD-4@AV biocomposite material was determined as 11.2 mg g−1 under optimum conditions. The reusability of A&XAD-4@AV biocomposite material was found to be suitable. For checking model adequacy, a regression model was derived using CCD to predict the responses and analysis of variance (ANOVA) and lack of fit test was performed. It was observed that the quadratic model, which was controlled and proposed, originated from experimental design data. The ANOVA showed a high coefficient of determination (R2 = 0.9896, R2Adj = 0.9800, R2Pred = 0.9633). Finally, developed and optimized method was applied effectively to wastewater for determining Pb(II) ions levels. The current study indicated that the prepared A&XAD-4@AV is an efficient material to remove of Pb(II) ions from IW.
AtıfScopus1WoS1OpenAlex1İncele - MakaleYalnız künye2024Scopus SJRQ3Functionalized and Ag-Loaded Nano-Delivery System for Doxorubicin: Loading, Controlled Release and Kinetic Studies
Aydogdu, Burcu; Kaplan Ince, Olcay; Ince, Muharrem; Unal, Ilkay
Multi-walled carbon nanotubes (fMWCNTs) that functionalized and loaded Ag nanoparticles (AgNPs) were investigated to adsorp doxorubicin hydrochloride (DXR). DXR release behavior efficiency was determined using kinetic studies. DXR agent was treated into fMWCNTs@AgNPs material with different drug loading rates. The material was successfully established and characterized using transmission electron microscopy, and fourier transform–infrared spectroscopy. Thermogravimetric analysis was performed to elucidate the effect of temperature on mass loss and X-ray diffraction analysis was systematically assessed the crystalline state of DXR. Various kinetic models including Higuchi, Baker Hixson-Crowell, and power-law were applied. It was revealed that DXR has more binding affinity to the fMWCNTs@AgNPs material system surface as a nanocarrier at pH 7.4 and showed more release at pH 5.0. Functionalized material confirmed its efficiency as pH-based drug delivery system. Used material can be utilized as promising nanocarriers, and findings will contribute to the rational design of novel delivery tools for drugs.
- MakaleAçık Erişim2024Scopus SJRQ3Synthesis and characterization of chitosan-based pH-sensitive biofilm: An experimental design approach for release of vitamin B12
Onal, Ali; Demir, Hulya; Ince, Olcay Kaplan; Ince, Muharrem
Hydrogels because of their unique potentials, such as highwater content and hydrophilicity, are of interest for the controlled release of drug molecules. In the present study, a biofilm was produced using chitosan, a natural polymer. Characterization analyses of the synthesized biofilm were performed using Fourier-transform infrared spectroscopy (FT-IR), thermogravimetric analysis-differential thermal analysis, x-ray diffraction, and scanning electron microscopy-energy dispersive x-ray spectrometry. The analysis results of the film before loading were compared to the analysis made after adding vitamin B12 to the film. The release percentage of vitamin B12 was investigated by using ultraviolet-visible spectrophotometery. The FT-IR bands of vitamin B12 were in the range of 2,800-3,500 cm-1 and 1,000 cm-1-1,750 cm-1. When pH increased from 3 to 7, release of vitamin B12 from the biopolymer increased up to pH 5. While examining the release potential, parameters, such as pH, initial concentration of vitamin B12, release time, and solution volume, were optimized by using response surface methodology. It was determined that with the increase in release time and the initial concentration, pH contributed positively to the release of vitamin B12. The following conditions were determined for release of vitamin B12 from the biofilm: pH: 4.2, initial concentration of vitamin B12: 54.0 mg L-1, the release time: 117 min, and volume of solution: 2.1 mL. The analysis of variance results showed that the determination coefficients for the use of synthesized biofilm in vitamin B12 release were high and R2 =0.9704.
AtıfScopus9WoS9OpenAlex10İncele - MakaleAçık Erişim2024Scopus SJRQ2Development of new generation cakes fortified with zinc oxide nanoparticles
Kaplan Ince, Olcay; Aydogdu, Burcu; Ince, Muharrem
This study aimed to develop new generation cakes that were fortified with calcined ZnO nanoparticles (CZnO), uncalcined ZnO nanoparticles (UCZnO), beads (B(CZnO)) synthesized by encapsulating the CZnO with sodium alginate (SA), and the beads (B(UCZnO)) synthesized by encapsulating the UCZnO with sodium alginate (SA) and investigated the zinc (Zn) release in fortified cakes in simulated body fluids (SBF). The present study represents a novel method for increasing intestinal absorption and bioavailability of dietary zinc with zinc nanoparticles for use in the preparation of Zn fortified cakes as a dietary supplement to compensate for zinc deficiency in humans. The results revealed that a rapid increase in the release time and rate in the SGF solution was noted in the UCZnO added cakes. It was attributed to increased intestinal absorption and bioavailability as a result of the ultra-small size of ZnO. Also, ZnO release kinetics in SBF was also studied and data were adjusted into different kinetic models involving zero-order, first-order, Higuchi, and Korsmeyer–Peppas models. The present investigation recommends adding UCZnO to the cakes to control and increase the release from the cakes.
AtıfScopus3WoS2OpenAlex3
İncele - MakaleYalnız künye2023Scopus SJRQ3Green Synthesis and Encapsulation of Superparamagnetic Magnetite for Mercury (II) Removal: Adsorption Isotherms, Adsorption Kinetics, and Thermodynamic Studies
Alp Kavlo, Hevidar; Ince, Muharrem; Kaplan Ince, Olcay; Aydogdu, Burcu; Ozcan, Cemile
Mercury (II) ions have significant ecological impacts. In the current study, magnetized iron oxide (Fe3O4) nanoparticles were green synthesized and encapsulated with alginate (ALG). The nanoparticles were converted into a composite (Fe3O4/ALG). The Fe3O4/ALG beads were used to remove Hg (II) from industrial wastewater. Characterization was performed by X-ray diffraction (XRD), scanning electron microscopy—energy dispersive spectroscopy (SEM-EDS), Fourier transform infrared spectroscopy (FT-IR), and thermogravimetric analysis-differential thermal analysis (TGA-DTA). A central composite design (CCD) approach was performed to define the experimental conditions providing the highest global adsorption efficiency and to optimize the pH, temperature and adsorbent mass. Hg (II) concentrations were determined by flame and electrothermal atomic absorption spectrometry (FAAS and ETAAS). The limits of detection (LOD) and quantification (LOQ) were 1.2 mg L−1 and 3.5 mg L−1 for FAAS and 0.2 µg L−1 and 0.5 µg L−1 for ETAAS, respectively. Additionally, Langmuir, Freundlich, and Temkin isotherm models were employed to determine the adsorption mechanism. The adsorption capacity of Fe3O4/ALG was determined to be 49.18 mg g−1 by the Langmuir model. Kinetic studies revealed that the adsorption of Hg (II) best fitted the pseudo-second order model. The Gibb’s free energy (ΔG°) values showed that the adsorption of Hg (II) on Fe3O4/ALG occurred spontaneously.
AtıfScopus8WoS8OpenAlex10İncele - MakaleAçık Erişim2022Ponza ile bakır ve kurşun iyonlarının adsorpsiyon karakteristikleri
Karacahan, Mehmet Kayra; Demirkiran, Nizamettin; Tanaydın, Zümra Bakıcı; Ince, Muharrem
Bu çalışmada, kesikli sistemde, ponza kullanılarak çözeltilerden Cu(II) ve Pb(II) iyonlarının uzaklaştırılması amaçlanmıştır. Adsorban miktarı etkisi (0.1-0.5g), Cu(II) ve Pb(II) iyon çözeltilerinin derişim etkisi (Cu(II) için; 3.2-31.8 ppm, Pb(II) için; 10.2-103.6 ppm), çözeltilerin pH etkisi (Cu(II) için 3-6.1(doğal pH), Pb(II) için 3-5.25(doğal pH)) gibi değişken parametrelerin etkileri incelenmiştir. Adsorban miktarının 0.4 g, çözelti iyon derişiminin 6.4 ppm ve pH değerinin 6.1 olduğu optimum şartlarda %91 bakır giderim verimi elde edilirken adsorban miktarının 0.4 g, çözelti iyon derişiminin 20.7 ppm ve pH değerinin 5.2 olduğu optimum şartlarda %97.7 kurşun giderim verimi elde edilmiştir. Deneysel olarak bulunan adsorpsiyon verilerine Langmuir, Freundlich, Temkin ve Harkins-Jura izoterm modelleri uygulanarak modellenmiş ve izoterm sabitleri hesaplanmıştır. Bakır ve kurşun iyonlarının adsorpsiyonunda Freundlich izoterm modeli deney verilerine en uygun model olarak belirlenmiştir. Bakır için ponzanın maksimum adsorplama kapasitesi 2.55 mg g⁻¹, kurşun için bu değer 10.28 mg g⁻¹ olarak bulunmuştur. Adsorpsiyon kinetiklerinin yalancı ikinci mertebeden kinetik modeline daha uyumlu olduğu belirlenmiştir. Farklı sıcaklıklarda standart serbest enerji değişimi (ΔG°), entalpi (ΔH°) ve entropi (ΔS°) değerleri belirlenmiştir. Yapılan çalışmada elde edilen sonuçlar, diğer adsorbanlarla karşılaştırıldığında ponzanın sulu çözeltilerden ağır metallerin gideriminde etkin, ekonomik ve alternatif bir adsorban malzemesi olabileceğini göstermiştir.
AtıfOpenAlex1TR Dizin1
İncele - MakaleYalnız künye2022Comparison of Some Physical and Chemical Properties of Kefir Obtained from Different Kefir Cultures and Brands of Milk
Ince, Muharrem; Ince, Olcay Kaplan; Eryilmaz, Haydar
In this study, three different kefir cultures were used to ferment five different brands of milk samples. pH, the dry matter, ash amount, carbon dioxide (CO2) amount, titratable acidity, 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging capacity, the reducing power, the Fe(II) ions chelating capacity, the total phenolic content (TPC), copper(II) ion reductive antioxidant capacity (CUPRAC) and mineral matter contents were investigated in kefir samples and results were evaluated statistically. When kefirs’ CUPRAC, TPC, DPPH free radical scavenging capacity, Mg, Zn, and Na concentrations are evaluated in terms of kefir culture, KC1, KC2, KC3, KC1, KC1, and KC1, had the highest values (p<0.05), respectively. If it is evaluated in terms of different brands of milk, kefirs’ CUPRAC, TPC, DPPH free radical scavenging capacity and Na concentrations were found highest (p<0.05) which were produced by M5, M2, M1, and M4, respectively. The data obtained from the experimental studies it was determined that the kefir cultures and milk used had an effect on the quality of the kefir.
AtıfOpenAlex3TR Dizin2İncele - MakaleAçık Erişim2022Scopus SJRQ3Adsorptive removal of nickel ions from wastewater by synthesized a novel biocomposite material and process optimization by response surface methodology
Ince, Muharrem; Ince, Olcay Kaplan; Alp, Hevidar
In the present study, a fixed-bed column study was performed using a novel biocomposite mate-rial, Amanita vaginata immobilized on Amberlite XAD-4 resin, to find out the adsorption behavior of nickel (Ni2+) ions from industrial wastewater. The influence of some important operating conditions including pH (3–7), biocomposite material amount (150–250 mg (XAD-4:Amanita vaginata, 5:1)) influent flow rate (4–8 mL min–1) besides Ni2+ ions initial concentration (20–40 mg L–1) on the uptake of Ni2+ solution were also optimized using a synthetic water solution. A central composite design combined with response surface methodology was utilized to maximize Ni2+ ions removal using A. vaginata immobilized on Amberlite XAD-4 resin as a biocomposite material in a column biosorption process. A mathematical model was derived from the central composite design approach for predicting responses and analysis of variance. Also, for checking model adequacy a lack of fit test was carried out. It was determined that the checked and proposed quadratic model was derived from the experimental design data. The biocomposite material adsorption capacity was calculated as 6.28 mg g–1. A high coefficient of determination (R2 = 0.9887) was presented by analysis of variance. Results confirmed that the amount of adsorbed Ni2+ amount did not change with the increase of the flow rate ratio and dose when the initial concentration of Ni2+ ions increased. The maximum adsorp-tion capacity of biocomposite material was achieved at 6.9 pH, 150.1 mg of biocomposite material amount, 7.8 mL min–1 of solution flow rate, and 39.7 mg L–1 of Ni2+ ions initial concentration. Finally, the developed method was applied to industrial wastewater to determine Ni2+ ions concentrations.
AtıfScopus4WoS4OpenAlex5İncele - MakaleAçık Erişim2022Scopus SJRQ3The use of Phanerochaete chrysosporium as an alternative bioremedia-tion tool of heavy metal, chemical oxygen demand and phosphate from landfill leachate
Yildirim, Numan; Kardas, Elif; Ince, Muharrem
In this study, in order to investigate the bioremediation efficiency of Phanerochaete chrysosporium, chemical oxygen demand (COD) reduction, total phosphate levels and heavy metal (Fe2+, Mn2+, Zn2+ and Cu2+) removal were determined in five different experimental groups (control, X, Y, Z, and T) under static culture conditions containing leachate at different incubation periods (5, 10, and 20 d). At the end of the 20th day of incubation, 84% Mn2+ and Zn2+ removal was achieved in X application group. In the same application group, 90.88% COD reduction was also obtained. The lowest total phosphate value was determined as 2.63 g L–1 in T group compared with control group (5.0 g L–1). Similar improvements have been identified in other application groups in terms of metal removal, total phosphate levels and COD reduction. As a result, the findings obtained from our study show that white rot fungus P. chrysosporium can be used as an alternative biological resource in the studies for improving landfill leachate in terms of metal removal efficacy, COD and total phosphate level reduction capacity.
AtıfScopus3WoS1OpenAlex3İncele - MakaleAçık Erişim2022Scopus SJRQ1Cadmium exposure in population: alcoholic beverage consumption and health risk assessment
Kaplan Ince, Olcay; Ince, Muharrem; Onal, Ali
Risk assessment of cadmium (Cd) for human health play a key role because of toxic effect. Researchers are undergoing constant development for modelling approaches to make a risk assessment. It was carried out a central composite design combining with response surface modeling to optimize and modeling of Cd2+ ions in this study. Also, this study was performed to provide information about possible risk associated with alcoholic beverage consumption. Some independent process parameters including contact time and pH were chosen for optimization. Under optimal parameters, 142.9 mg g−1 was determined as Cd2+ ions removal effectiveness. Significance independent parameters and their interactions were checked using analysis of variance. These results were verified by correlation coefficients (R2 = 0.9967) of the statistical prediction. Estimated daily intake (EDI) and target hazard quotients (THQ) were calculated, to assess health risk. The Cd2+ ions EDI values (µg/day/person) were less than the recommended dietary allowance values and also, its THQ value was less than 1, also. When the obtained results compared with the levels set by regulatory authorities, the studied alcoholic beverages consumption do not pose a toxicological risk. Graphical abstract: [Figure not available: see fulltext.]
AtıfScopus3OpenAlex3İncele - MakaleYalnız künye2021Determination of Antioxidant Capacity, Phenolic and Elemental Composition in Syriac (Mardin) Wines by using Chromatographic and Spectrophotometric Methods
Sanyurek, Nesrin Karaca; Ince, Olcay Kaplan; Aydogdu, Burcu; Ince, Muharrem
Free radicals are responsible for many health problems, especially oxidative stress-related diseases. With conscious nutrition and the use of natural antioxidants, it is now possible to cope with these diseases or minimize their effects. The aim of this study was to determine pH, total acidity, total SO2, free SO2, relative SO2, dry matter, density, alcohol content, reducing sugar, ash, CUPRAC, DPPH free radical scavenging capacity, total phenolic content, elemental composition, and some phenolic compounds of Syriac (Mardin) wines. Estimated daily intake (EDI), target hazard quotients (THQ), total target hazard quotients (TTHQ), and relative risk (RR) were calculated, to assess a health risk resulting from regular consumption of Syriac wines. The elements EDI values through consumption of wines were less than the recommended dietary allowance values. Obtained THQ values were less than 1. When the obtained results are compared with the levels set by regulatory authorities, the investigated wine consumption does not pose a toxicological risk based on EDI, THQ, TTHQ, and RR values. In addition, this study showed that the Syriac wine’s antioxidant capacities are high and rich in phenolic compounds and elements.
AtıfScopus1WoS1OpenAlex3İncele - MakaleYalnız künye2021Scopus SJRQ1Experimental design approach for ultra-fast nickel removal by novel bio-nanocomposite material
Ince, Olcay K.; Aydogdu, Burcu; Alp, Hevidar; Ince, Muharrem
In the present study, novel chitosan coated magnetic magnetite (Fe3O4) nanoparticles were successfully biosynthesized from mushroom, Agaricus campestris, extract. The obtained bio-nanocomposite material was used to investigate ultra-fast and highly efficient for removal of Ni2+ ions in a fixed-bed column. Chitosan was treated as polyelectrolyte complex with Fe3O4 nanoparticles and a Fungal Bio-Nanocomposite Material (FBNM) was derived. The FBNM was characterized by using X-Ray Diffractometer (XRD), Scanning Electron Microscopy-Energy Dispersive X-Ray Spectroscopy (SEM-EDS), Fourier Transform Infrared spectra (FTIR) and Thermogravimetric Analysis (TGA) techniques and under varied experimental conditions. The influence of some important operating conditions including pH, flow rate and initial Ni2+ concentration on the uptake of Ni2+ solution was also optimized using a synthetic water sample. A Central Composite Design (CCD) combined with Response Surface Modeling (RSM) was carried out to maximize Ni2+ removal using FBNM for adsorption process. A regression model was derived using CCD to predict the responses and analysis of variance (ANOVA) and lack of fit test was used to check model adequacy. It was observed that the quadratic model, which was controlled and proposed, was originated from experimental design data. The FBNM maximum adsorption capacity was determined as 59.8 mg g−1. Finally, developed method was applied to soft drinks to determine Ni2+ levels. Reusability of FBNM was tested, and the adsorption and desorption capacities were not affected after eight cycles. The paper suggests that the FBNM is a promising recyclable nanoadsorbent for the removal of Ni2+ from various soft drinks.
AtıfScopus11WoS11OpenAlex7İncele - MakaleAçık Erişim2021Scopus SJRQ3A novel macrofungus for the biosorption of hazardous dye and its reuse potential: Experimental design approach using response surface methodology
Ince, Olcay Kaplan; Alp, Hevidar; Ince, Muharrem; Onal, Ali
In the present study, a novel biosorbent, namely Agaricus campestris, was used for the removal of Methylene Blue (MB) from an aqueous medium. The biosorbent was characterized using fourier-transform infrared spectrometer spectra, scanning electron microscopy-energy dispersive X-ray, and thermogravimetric analysis. The influence of important process parameters including pH (4–7), temperature (25°C–35°C), contact time (15–25 min), and biosorbent amount (40–80 mg) on the uptake of MB solution were also optimized, which significantly affected the removal efficiency of MB. A central composite design (CCD) combined with response surface modeling (RSM) was carried out to maximize MB removal by A. campestris for the adsorption process. A regression model was derived using RSM to predict the responses and analysis of variance (ANOVA), and to check model adequacy lack of fit test was used. The A. campestris adsorption capacity was determined as 24.2 mg g–1. The ANOVA showed a high coefficient of determination (R2 = 0.9987). This study clearly revealed that RSM was one of the most effective and appropriate method for the optimization of operating conditions. The possibility of reusing A. campestris was also investigated and, as a result, it was found quite possible and showed high performance in the recovery of MB.
AtıfScopus2WoS1OpenAlex2İncele - MakaleAçık Erişim2021Scopus SJRQ2Exposure to copper and risk assessment for human health via consumption of alcoholic beverages
Ince, Muharrem; Kaplan Ince, Olcay; Onal, Ali
Present study was performed using a Box–Behnken Design (BBD) combined with a response surface methodology (RSM). The ultimate goal of this research was to apply BBD for modeling of copper (Cu2+) ions from alcoholic beverages and evaluate health risk assessment of Cu2+ via consumption of alcoholic beverages. The importance of independent paramaters and their interactions were examined using analysis of variance (ANOVA). Natural clay was investigated to remove Cu2+ ions from some alcoholic beverage samples including beer and wine. X-ray diffraction (XRD), fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) coupled with energy dispersive X-ray (EDS) analysis were used for adsorbent characterization. Same analyzes were applied for Cu2+ loaded clay. In addition, experimental studies showed that Freundlich isotherm was better than Langmuir isotherm. Finally, optimized method was applied to alcoholic beverages. Besides target hazard quotients (THQ), estimated daily intake (EDI) values were calculated, to assess a health risk resulting from these alcoholic beverages regular consumption. The EDI values of Cu (µg/day/person) through consumption of investigated drinks were less than the recommended dietary allowance values. Also, the THQ values of Cu2+ were less than 1. According to estimated target hazard, it can be said no long life health concerns of Cu2+ is associated with the consumption of studied drinks. Obtained results were compared with the data from literature and levels set by regulatory authorities, it can be clearly stated that the consumption of mentioned alcoholic beverages do not pose a toxicological risk.
AtıfScopus14WoS10OpenAlex11İncele - MakaleAçık Erişim2020Adsorption of Copper and Cadmium with Perlite and Comparison of Adsorption Properties
Karacahan, Mehmet Kayra; Demirkiran, Nizamettin; Ince, Muharrem; Bakıcı Tanaydın, Zümra
This study, the effectiveness of perlite for the removal of Cu (II) and Cd (II) ions from aqueous medium was investigated by adsorption method. Using perlite adsorbent, parameters such as initial concentration, initial pH, adsorbent dosage and contact time affecting Cu (II) and Cd (II) ions adsorption from aqueous solutions were investigated. Initial concentration of copper (II) ions, initial pH value, adsorbent amount, contact time respectively 3.2 ppm, natural pH 6.49, 2 g, during the 180 minutes adsorption 94% of copper ions adsorbed, the initial concentration of cadmium (II) ions solution, initial pH, adsorbent amount, contact time 5.6 (ppm), natural pH 5.25, 2 g, 180 minutes, respectively, 77% adsorbed. It was determined that the adsorption data fit the Langmuir isotherm for copper ions and Freundlich isotherm for cadmium ions, and the kinetic data of copper and cadmium ions fit the false second order model. Including the thermodynamic parameters of adsorption, Gibbs free energy change (ΔG°), enthalpy (ΔH°) and entropy (ΔS°) values calculated at 20oC are for copper 3.1 kJ mol-1, -55.52 kJ mol-1, -0.2 kJ mol-1 K-1 , respectively and for cadmium, 7.14 kJ mol-1, -28.02 kJ mol-1, -0.12 kJ mol-1 K-1, respectively. The results showed that the adsorption of these metal ions on the perlite is exothermic and feasible at 20-50°C.
AtıfTR Dizin6İncele - MakaleYalnız künye2020Scopus SJRQ2Evaluation the Weekly Intake of Some Wild Edible Indigenous Mushrooms Collected in Different Regions in Tunceli, Turkey
Alp, Hevidar; Ince, Muharrem; Ince, Olcay Kaplan; Onal, Ali
The quantity of some essential and non-essential elements of wild edible mushroom samples collected from Tunceli Province of Turkey was determined by using flame and electrothermal atomic absorption spectrometer after microwave digestion. The method accuracy was corrected using standard reference material (NIST SRM 1547-Peach Leaves). The essential element concentrations of analyzed mushroom samples were determined in the range of 0.036–0.563 mg kg−1 for calcium, 1.28–2.55 mg kg−1 for magnesium, 0.054–0.188 mg kg−1 for sodium, 1.00–4.57 mg kg−1 for copper, 212–480 mg kg−1 for iron, and 75–151 mg kg−1 for zinc but cobalt and chromium were not detected. Based on results, there were statistically significant differences between the element contents of analyzed mushroom species. Consequently, according to this study results, the weekly intake and target hazard quotient values of the elements show that the consumption of these mushrooms does not threaten human health. [Figure not available: see fulltext.].
AtıfScopus9WoS8OpenAlex9İncele - MakaleAçık Erişim2020Scopus SJRQ3Biosorptive removal of eriochrome black-T using agaricus campestris: Parameters optimization with response surface methodology
Alp, Hevidar; Ince, Muharrem; Ince, Olcay Kaplan; Onal, Ali
In this study, Eriochrome Black T (EBT) removal from aqueous media by Agaricus campestris (AC) which is an eco-friendly biosorbent was investigated using a central composite design (CCD) combined with response surface methodology. The CCD was chosen as the statistical prediction method to reduce the number of experiments which, in turn, will directly save time and chemicals. To opti-mize the process, various experimental independent variables such as the pH of the solution, contact time, adsorbent dosage and temperature were selected. The optimal experimental conditions were obtained as 6.5, 30°C, 20 min and 20 mg, for solution pH, temperature, contact time and adsorbent dosage, respectively. Under these optimized conditions, maximum EBT (100 mg L–1 initial concentra-tion) removal efficiency was calculated as 64.2 mg g–1. The independent variables and their interaction significance were checked using analysis of variance and it was found that the EBT biosorption on AC was highly significant (p < 0.001). The results were justified by the relatively high correlation coefficients (R2 = 0.9967) of the statistical prediction. The EBT biosorption was confirmed by fourier transform infrared spectroscopy (FTIR) analysis monitoring the functional groups during EBT biosorption on AC. This was the first report on the parameter optimization of EBT biosorp-tion using AC in an experimental design. The used biosorbent was characterized by FTIR, scanning electron microscope coupled with energy dispersive spectrometer and thermogravimetric analysis. The proposed biosorption process efficiently removed EBT, present in various aqueous mediums and can be used in industrial processes.
AtıfScopus17WoS12İncele - MakaleAçık Erişim2020Scopus SJRQ4Investigation of curcumin role on doxorubicin-induced tissue damage in terms of trace metal levels using etaas
Ince, Olcay Kaplan; Kandemir, Fatih Mehmet; Ince, Muharrem; Benzer, Fulya; Onal, Ali; Kucukler, Sefa
Doxorubicin (DXR) is one of the commonly used chemotherapeutic agents, which is highly toxic and causes gastrointestinal and cardiac toxicity. Curcumin is used as a spice and coloring agent in food, but also possesses anti-proliferating, potent antioxidant, antitumor-promoting and anti-carcinogenic properties in vitro and in vivo. In this study, the change in element concentrations in the tissues of healthy animals was examined by administering doxorubicin and curcumin separately, or both at the same time. For this purpose, 35 wistar albino male rats were selected and randomly divided into five groups of seven each. The objective of this study was to assess and compare the levels of copper, iron, zinc and selenium in the liver, kidney, heart, and testis of the control group and in the doxorubicin-induced tissues. According to the results, the Cu, Fe, Zn, Se amounts and the Cu/Fe, Cu/Zn, and Cu/Se ratios were present at different levels in each of the five groups. In terms of element concentration, the most affected tissue by doxorubicin application is the heart, and the least affected is the kidney. The ratios of Cu/Fe and Cu/Se in the liver and the heart were highest in Group II and Group III, respectively.
AtıfScopus2WoS2OpenAlex2İncele - MakaleYalnız künye2019Scopus SJRQ4Application of response surface methodological approach to optimize removal of Cr ions from industrial wastewater
Ince, Muharrem; Ince, Olcay Kaplan
In the present study, the adsorption of chromium (Cr) onto clay using response surface methodology (RSM) was investigated as an efficient approach for examining predictive model building and optimization. To optimize experimental variables and predictive regression models, statistical design models were carried out. A five-level four-fac-tor central composite design (CCD) combined with RSM was performed with synthetic aqueous solutions on natural clay. The experimental variables included pH and agitation speed and were selected for optimization. The Cr ions ideal removal conditions were obtained using pH 5.0, contact time 23.0 minutes, adsorbent dosage of 69.4 mg, and agitation speed of 135 rpm. Chromium removal efficiency was found at 23.16 mg g-1. The independent variables significance and their interactions were verified by means of the analysis of variance (ANOVA). These results were justified by the relatively high correlation coefficients (R2 = 0.9902) of the statistical prediction. Clay and Cr loaded clay were characterized by X-ray dif-fractometer (XRD) and energy dispersive spectroscopy (EDS). The proposed adsorption process efficiently removed the Cr ions present in various aqueous media and was also applied to various industrial wastewaters.
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