Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Karaca Sanyürek, Nesrin(2)
- Çakır, Atilla(2)
- Adigüzel, Ragip(1)
- Aksoy, A.(1)
- Alatas, Mevlut(1)
- Albayrak, S.(1)
- Aydin, Sevinc(1)
- Aydin, Çağlar Mert(1)
- Aydinl, Sevinc(1)
- Aydın, Sevinç(1)
- Batan, Nevzat(1)
- Buldurun, Kenan(1)
- Bursal, Ercan(1)
- Cinar, A. E. Korkmaz(1)
- Odabaşioğlu, Mehmet İlhan(1)
- Odabaşıoğlu, Mehmet İlhan(1)
- Paksoy, M. Y.(1)
- Turan, Nevin(1)
- İşlek, Fırat(1)
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ1Comprehensive Analysis of Phytochemical Compounds in Seeds of Indigenous Grape Varieties Cultivated in Southeastern Anatolia: Fatty Acids, Tocopherols, Phytosterols, Vitamins, and Antioxidant Properties
Odabaşioğlu, Mehmet İlhan; Çakır, Atilla; Karaca Sanyürek, Nesrin; İşlek, Fırat
Aim: In this study, the phytochemical composition of the seeds of twelve different local grape (Vitis vinifera L.) varieties traditionally cultivated in the Southeastern Anatolia Region (Diyarbakır, Türkiye) was investigated using a holistic approach. The main objective of the study was to evaluate the associations of the effects of berry skin colour, the ripening stage and utilization type on the fatty acid profile, tocopherol and phytosterol contents, vitamin K and D levels, antioxidant capacity (DPPH) and lipid peroxidation (MDA) of grape seeds. Method: The seeds of grape varieties belonging to four different colour groups, grown on their own roots, were harvested during the 2017 growing season and analysed. Fatty acid composition was determined by gas chromatography (GC), vitamin and phytosterol contents by HPLC-UV, MDA content by the thiobarbituric acid reactive substance (TBARS) method, and antioxidant capacity by the DPPH radical scavenging assay. Findings: Linoleic acid was identified as the predominant fatty acid in all varieties (53.68–67.06%), followed by oleic acid (13.80–27.32%). α-Tocopherol was identified as the predominant tocopherol form (1.597–4.703 mg kg−1), whilst β-sitosterol was the phytosterol component present at the highest level (915.67–3340.42 µg g−1). Statistically significant varietal differences were detected for most measured phytochemical parameters. Group-wise differences associated with berry skin colour and ripening stage were observed for selected traits. Overall, varietal differences appeared to be more pronounced than those associated with berry skin colour or ripening stage. It was observed that the differences in phytochemical composition between the various commercial classifications of grapes were very limited. Result: The findings reveal that the seeds of the local grape varieties studied exhibit a rich phytochemical profile and represent an important source of bioactive compounds that could be utilised, particularly in the functional food, nutraceutical and cosmetics industries. The ‘Tahannebi’ variety stood out as the one with the highest values across many parameters. Differences observed among samples of the same cultivar collected from different vineyards suggest that vineyard-specific conditions may contribute to variation in selected phytochemical traits. Future multi-year and multi-location studies are needed to confirm the stability of these phytochemical profiles and to further clarify genotype × environment interactions.
- MakaleAçık Erişim2026Scopus SJRQ2Ultrasound assisted extraction of phenolic compounds from Tunceli walnut varieties using deep eutectic solvents
Aydin, Çağlar Mert
This study aimed to improve a green way to enhance extraction of bioactive compounds from walnut, and to evaluate the effect of altitude on walnut bioactive content. Total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity were evaluated as bioactive compounds of walnut. In comparison with conventional solvents (water, ethanol and methanol), three DESs (Deep eutectic solvents) were formed from choline chloride, zinc chloride, and sorbitol as HBA and ethylene glycerol as HBD. The DESs (DES-1 and DES-2) generated from choline chloride and zinc chloride exhibited better extraction efficiencies for any bioactive compound than that of conventional solvents. Especially, the DES formed from the choline chloride: ethylene glycerol demonstrated the highest extraction efficiency. However, sugar-based DES showed the worst extraction efficiency. The altitude significantly affected extracted bioactive contents from walnuts (Hozat 1000m, Ovacik 1300m and Nazimiye 1550m). Walnut’s extracted bioactive content ordinarily decreased as the altitude increased, regardless of solvent type used in extraction. The result is a light to enhancing knowledge as to DES usage and its extraction efficiency of bioactive compounds for food applications. In addition, it gives better understanding of altitude effect on the content of bioactive compounds in walnuts.
AtıfScopus1WoS1İncele
- MakaleYalnız künye2023Scopus SJRQ3Comprehensive Evaluation of the Relationships Between Grape Skin Color/Ripening Time and Antioxidative Capacity, Some Phytochemicals, and Fatty Acid Compositions of Their Seeds
Çakır, Atilla; Odabaşıoğlu, Mehmet İlhan; Karaca Sanyürek, Nesrin; Aydın, Sevinç
It has been proven that grapes, which are widely cultivated around the world, have positive health effects. However, the phytochemical composition of lesser-known local varieties of Vitis vinifera L., which has a very wide range of varieties, is still being studied. The aim of this study was to determine the effects of skin color and ripening time on the phytochemical compositions of grape seeds. As a plant material local grape varieties cultivated in Southeastern Anatolia (Turkey) were used. The results showed that grape skin color has an effect on vitamin K1, vitamin K2, vitamin D3, δ‑tocopherol, stigmasterol, ergosterol, myristic acid, oleic acid, trans-elaidic acid, and the monounsaturated fatty acid (MUFA) and saturated fatty acid (SFA) contents of seeds. The seeds of grape varieties with colored skins were richer in K2, D3, stigmasterol, oleic acid, trans-elaidic acid, and MUFAs, while the seeds of grape varieties with white skins were richer in K1, δ‑tocopherol, ergosterol, and SFAs. The ripening time of the grapes was found to have a partial effect on the fatty acid compositions of the seeds, but without any effect on linoleic acid contents. As the ripening time was delayed, there was an increase in oleic acid and MUFA contents of the seeds, while there was a decrease in SFA contents. In general, increased vitamin K1 contents of the seeds were parallel to decreases in vitamins K2, D2, and D3, as well as α‑tocopherol content and antioxidant activity. The seeds of grape varieties that have colored skins were found to have more suitable compound compositions for use in the production of functional foods that support human and animal health. In addition, it was concluded that grape berries that ripen late may be more favorable for grapeseed oil production.
AtıfScopus3WoS4OpenAlex3İncele
- MakaleYalnız künye2021FATTY ACID CONTENT AND FREE RADICAL SCAVENGING (DPPH) ACTIVITIES OF SOME OF BRYOPHYTES EXTRACTS
Aydinl, Sevinc; Alatas, Mevlut; Batan, Nevzat
In this study, DPPH and fatty acid contents were investigated of some taxa belonging to Neckeraceae (Alleniella complanata, Alleniella besseri, Exsertotheca crispa) and Hypnaceae (Hypnum cupressiforme, Hypnum resupinatum, Hypnum andoi) family collected from Kamilet Valley (Artvin-Arhavi) in 2017. DPPH free radical scavenging activity was determined according to the method developed by Brand-Williams et al. The fatty acids in extracts were analyzed via gas chromatography after transforming them into methyl esters. According to the obtained results, it was determined that the DPPH scavenging effects of taxa from Hypnaceae family were significantly higher than those of taxa from Neckeraceae family, and that the free radical scavenging effects of taxa from Hypnaceae family varied depending on the amount of extract. The saturated fatty acids content of the Neckeraceae and the unsaturated fatty acids of the Hypnaceae were found to be richer (p<0.001). The high DPPH activity in our study, especially in Hypnum species, suggested that Hypnum species were richer in terms of phenolic content. These compounds can be used in the pharmaceutical, cosmetic and food sectors, if both of these species are phenolic and fatty acid content can be obtained as pure.
AtıfWoS2İncele
- MakaleYalnız künye2021ANTIOXIDANT ACTIVITIES AND SOME BIOCHEMICAL CONTENTS OF THE SEEDS OF THE OKUZGOZU AND BOGAZKERE (Vitis vinifera L.) GRAPE VARIETIES GROWN IN TURKEY
Aydin, Sevinc
The Vitis vinifera L. grape species is a fruit that is the most prevalently grown in the whole world and has economic significance. It is known that, due to its climate conditions, Turkey has rich resources in terms of Vitis vinifera L. With this study, we aimed to determine the phenolic, vitamin and fatty acid contents of the Okuzgozu and Bogazkere varieties of Vitis vinifera L. and see the effects of these contents on antioxidant activity. Fatty acids in the lipid extract were analyzed by gas chromatography after conversion into methyl esters. For flavonoid and vitamin analyses, a high-performance liquid chromatography device (HPLC-UV. Shimadzu) was used. Antioxidant activity was determined by Radical Scavenging Activity (DPPH) and Lipid Peroxidation (MDA) experiments, As a result of the study, some saturated and unsaturated fatty acid, phenolic compound and vitamin contents of the two varieties were obtained. It was observed that the amounts of unsaturated fatty acids, whose effects on antioxidant activity are known, in the Okuzgozu variety were significantly higher than those in the Bogazkere variety. The results on phenolic and vitamin compounds revealed higher amounts in the Okuzgozu variety in comparison to Bogazkere as in the case of fatty acids. The finding that these contents and antioxidant activity were in proportion suggested that the antioxidant effect of the Okuzgozu variety is higher. If the substances that provide this effect are correctly isolated from the plant, they may be used beneficially in both the food and pharmaceutical sectors.
- MakaleAçık Erişim2016Scopus SJRQ3Spectroscopic, Thermal and Antioxidant Properties of Novel Mixed Ligand-Metal Complexes Obtained from Saccharinate Complexes and Azo Dye Ligand (mnppa)
Turan, Nevin; Adigüzel, Ragip; Buldurun, Kenan; Bursal, Ercan
The novel mixed ligand-metal complexes with a general formula [M(Sac)(2)(H2O)(2)L-2]center dot nH(2)O) [M = Mn(II), Co(II), Ni(II), Cu(II) and Cd(II), L=5-Methly-4-(4-nitrophenylazo)-2H-pyrazole-3-ylamine (mnppa)] have been synthesized and characterized by elemental analyses, IR, UV-VIS, magnetic susceptibility mass spectra and thermogravimetry-differential thermal analysis (TGA-DTA). Each metal (II) ion is octahedral coordinated by two sac, two mnppa and two aqua ligands. The antioxidant properties of mixed ligand-metal complexes were determined by different in vitro methods such as ABTS, DPPH, FRAP and CUPRAC assays. The results of metal complexes were compared with standard antioxidant compounds.
AtıfWoS30OpenAlex30İncele
- MakaleYalnız künye2015Scopus SJRQ3An investigation on antioxidant and antimicrobial activities of four Inula helenium L. taxa
Albayrak, S.; Cinar, A. E. Korkmaz; Paksoy, M. Y.; Aksoy, A.
The antioxidant activities of methanol (ME), ethanol (EE), water (WE) and ethyl acetate (EAE) extracts of four Inula helenium L. taxa (I. helenium ssp. orygalis (Boiss.) Grierson, I. helenium ssp. pseudohelenium Grierson, I. helenium ssp. turcarasemosa Grierson and I. helenium ssp. vanensis Grierson) were investigated. The phosphomolybdenum assay, beta-carotene linoleate bleaching and DPPH radical scavenging activity were used to evaluate the antioxidant capacity. The total phenolic contents determined by Folin-Ciocalteu assay of the extracts ranged from 4.18 to 102.91 mg gallic acid equivalents (GAE)/g dry extract. The extracts showed considerable effect on reducing the oxidation of beta-carotene. The highest radical scavenging activity was obtained for ME of I. helenium ssp. orygalis in DPPH assay. ME, EE and EAE of four Inula helenium taxa showed significant antibacterial activity against 13 bacteria tested. WEs had no inhibitory effect against bacteria tested except for I. helenium ssp. orygalis. EE of I. helenium ssp. orygalis was only effective against C. albicans.
AtıfWoS8İncele


