Sürdürülebilir Kalkınma Amaçları

• 2

Yazarlar

• Zengin, Gokhan(2)
• Ak, Gunes(1)
• Angeloni, Simone(1)
• Babacan, Ebru Yuce(1)
• Bouyahya, Abdelhakim(1)
• Cakilcioglu, Ugur(1)
• Caprioli, Giovanni(1)
• Cziáky, Zoltán(1)
• Dall'Acqua, Stefano(1)
• Darendelioglu, Ekrem(1)
• Ibrahime Sinan, Kouadio(1)
• Jekő, József(1)
• Kaplan, Alevcan(1)
• Maggi, Filippo(1)
• Mahomoodally, Mohamad Fawzi(1)
• Mustafa, Ahmed M.(1)
• Sadeer, Nabeelah Bibi(1)
• Sinan, Kouadio Ibrahime(1)
• Yagi, Sakina(1)
• Yavuz Paksoy, Mehmet(1)

• MakaleYalnız künye2024Scopus SJRQ3/r/munzur/1547
  Analyzing the Chemical Constituents and In Vitro Biological Effects of Extracts Artemisia absinthium L. Extracts Obtained Using Different Methodologies and Solvents

  Yagi, Sakina; Zengin, Gokhan; Ibrahime Sinan, Kouadio; Yavuz Paksoy, Mehmet; Cziáky, Zoltán; Jekő, József; Dall'Acqua, Stefano

  The present study aimed to investigate the chemical constituents of different extracts from aerial parts of A. absinthium and to evaluate their antioxidant and enzyme inhibition activity. Extracts were prepared by maceration, infusion or Soxhlet techniques. Results showed that the highest total phenolic and flavonoids contents was recorded respectively from the hexane extract prepared by maceration and ethyl acetate extract obtained by Soxhlet method. The characteristic compounds of Artemisia species artemetin, casticin, sesartemin and yangambin in addition to coumarins were identified in all extracts. Aqueous extract obtained by infusion exerted the highest radical scavenging and ions reducing properties while that prepared by maceration displayed the highest chelating power. Methanol extracts obtained by the two methods of extraction exerted the highest anti-Tyr activity while that obtained by maceration showed the best α-glucosidase inhibition activity. These findings indicated that A. absinthium is a rich source of bioactive molecules with possible therapeutic applications.

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  AtıfScopus2·OpenAlex3

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• MakaleYalnız künye2021Scopus SJRQ2/r/munzur/2847
  Two Medicinal Plants (Alkanna trichophila and Convolvulus galaticus) from Turkey: Chemical Characterization and Biological Perspectives

  Mahomoodally, Mohamad Fawzi; Zengin, Gokhan; Sinan, Kouadio Ibrahime; Ak, Gunes; Sadeer, Nabeelah Bibi; Angeloni, Simone; Mustafa, Ahmed M.; Caprioli, Giovanni; Maggi, Filippo; Cakilcioglu, Ugur

  The aim of the present study was to quantify selected phenolic compounds, determine antioxidant activity and enzyme inhibitory effects of the aerial parts of Alkanna trichophylla Hub.-Mor. (A. trichophylla) and Convolvulus galaticus Rost.ex Choisy (C. galaticus) extracts prepared by homogenizer-assisted extraction (HAE), maceration (MAC) and infusion techniques. This is the first time such study has been designed to validate the phytochemical composition and bioactivity of these plants. Multivariate analysis was conducted on collected data. Rutin and caffeoylquinic acid derivatives were the most significant compounds in A. trichophylla and C. galaticus, respectively. The highest antioxidant activity of A. trichophylla was mostly exhibited by HAE/methanolic extracts as determined by DPPH, ABTS, FRAP (51.39, 112.70 and 145.73 mg TE/g, respectively) and phosphomolybdenum (2.05 mmol TE/g) assays. However, significant antioxidant activities varied within the extracts of C. galaticus. HAE/methanolic extract of A. trichophylla significantly depressed AChE (2.70 mg GALAE/g), BChE (5.53 mg GALAE/g) and tyrosinase (26.34 mg KAE/g) activities and that of C. galaticus inhibited AChE (2.04 mg GALAE/g), tyrosinase (31.25 mg KAE/g) and α-amylase (0.53 mmol ACAE/g) activities significantly. We concluded that HAE was the most efficient extraction technique as high yield of compounds and promising bioactivities were recorded from extracts prepared. Multivariate analysis showed that types of solvents influenced recovery of compounds and biological activities. This research study can be used as one methodological starting point for further investigation on these plants as all results are clearly promising and open the door to further research challenges such as cytotoxicity evaluation, molecular docking analysis, and more screening of pharmacological actions.

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  AtıfScopus12·OpenAlex10

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