Sürdürülebilir Kalkınma Amaçları

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Araştırmacılar(6)

• Camas, Anil Sazak
• Camas, Mustafa
• Celik, Fatih
• Korkmaz, Şengül A.
• Sahilli, Yeliz Çakır
• Seyhaneyildiz Can, Şafak

• MakaleAçık Erişim2021Scopus SJRQ2/r/munzur/2810
  Comparative Toxicity of Alpha and Gamma Iron Oxide Nanoparticles in Rainbow Trout: Histopathology, Hematology, Accumulation, and Oxidative Stress

  Gürkan, Mert; Gürkan, Selin Ertürk; Yılmaz, Sevdan; Ateş, Mehmet

  In this study, alpha and gamma iron oxide nanoparticles, characterizations, toxic effects after being exposed to rainbow trout (Oncorhynchus mykiss) at 0, 1, 10 and 25 mg/L concentrations for 10 days, and then 10-day recovery period without any nanoparticle exposure were examined for histopathological (kidney, liver and gill), hematological, iron accumulation and potential for oxidative stress (TBARS and GSH). Histopathological damages significant at the exposure of increasing concentrations of both nanoparticles (increase in melanomacrophage aggregations, epithelial tissue deformations, cytoplasmic vacuolizations, fatty changes, necrosis, pyknosis, hyperplasia, hypertrophy, lamellar fusions, capillary dilatations). Gamma nanoparticles were determined to accumulate more than the alpha nanoparticles. The most Fe accumulation was detected in the liver. The findings of oxidative stress parameters showed that both nanoparticles have the potential to generate oxidative stress. It was concluded that the exposure of alpha and gamma nanoparticles at specified concentrations and durations had a toxic effect on rainbow trout and the toxicity of these nanoparticles was similar.

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  AtıfScopus18·WoS12·OpenAlex16

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• MakaleAçık Erişim2021Scopus SJRQ3/r/munzur/2583
  Pohlia hedw. And oleolophozia l.söderstr., de roo & hedd. species new to turkey and south-west asia

  Erata, Hüseyin; Özen, Öznur; Batan, Nevzat; Alataş, Mevlüt

  Pohlia lescuriana (Sull.) Ochi and Oleolophozia perssonii (H.Buch & S.W.Arnell) L.Söderstr., De Roo & Hedd. have been identified as new to Turkey and South-West Asia, following a recent bryological excursion in Giresun province of Turkey. The genus Oleolophozia L.Söderstr., De Roo & Hedd. is also new to Turkey. In this paper, brief descriptions, illustrations, information about geographic distribution, ecology and comparisons with morphologically similar taxa are given. A key to Pohlia Hedw. taxa in Turkey is added.

  AtıfScopus4·WoS4·OpenAlex12

  İncele
• MakaleYalnız künye2020/r/munzur/4404
  Ecotoxicity Study of Iron Oxide Nanoparticles on Chlorella Sp. and Daphnia Magna

  Ertit Tastan, Burcu; Kars Durukan, Ilknur; Ates, Mehmet

  Nanoparticles have great impact due to their tremendous industrial applications. However, their applications have produced toxicity effects on the aquatic environments and their detailed analyses are not clearly understood. Iron oxide nanoparticles (Fe2O3 NPs) are being used extensively in many industries but are considered highly toxic to aquatic species residing in surface waters. This paper demonstrates the acute toxicity of alpha-Fe2O3 and gamma-Fe2O3 NPs in two aquatic species. The effects of various concentration (0, 50, 100, 250, 500 and 1000 mg/L) of alpha-Fe2O3 and.-Fe2O3 on the sensitivity response of the Chlorella sp. and D. magna were investigated. The growth of microalgal decreased with increased concentration of the alpha-Fe2O3 and gamma-Fe2O3 NPs concentrations but did not show a significant toxic effect. The EC50 concentration value was 500 mg/L and LD50 concentration value was 1000 mg/L for alpha-Fe2O3 treated daphnids in 72 h, respectively. The findings demonstrate the significant evidence in understanding acute toxicity of Fe2O3 NPs for environmental protection as part of risk assessment strategies.

  AtıfWoS6

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• MakaleAçık Erişim2020Scopus SJRQ2/r/munzur/3823
  New national and regional bryophyte records, 63

  Ellis, L.T.; Afonina, O.M.; Czernyadjeva, I.V.; Konoreva, L.A.; Potemkin, A.D.; Kotkova, V.M.; Alataş, M.; Blom, H.H.; Boiko, M.; Cabral, R.A.

  AtıfScopus21·OpenAlex23

  İncele
• MakaleYalnız künye2020Scopus SJRQ3/r/munzur/3764
  Potential anesthetic properties of bay leaf (Laurus nobilis) essential oil compared with 2-phenoxyethanol on blue dolphin cichlid, cyrtocara moorii

  Kizak, Volkan; Can, Erkan; Seyhaneyildiz Can, Şafak

  The efficacy of Bay leaf (Laurus nobilis) essential oil (LnEO) as a herbal anesthetic agent was evaluated with 2-Phenoxyethanol (2-PE) in Blue Dolphin Cichlid, Cyrtocara moorii. Fish were exposed to different anesthetic concentrations and the lowest effective concentrations (LECs) were determined according to deep anesthesia (AD<3 min) and full recovery (RF<5 min) times. LnEO showed anesthetic properties, and all applied concentrations of both agents induced AD in C. moorii. The LECs of LnEO and 2-PE for C. moorii were determined as 800 µl L-1 (AD; RF → 183 ± 6.3 s; 191 ± 2.6 s) and 600 µl L-1 (AD; RF → 171 ± 3.2 s; 239 ± 4.9 s), respectively. Significant differences were found between anesthetic agents in terms of deep anesthesia and full recovery times for the same concentrations (p<0.05). Induction and recovery times decreased with increasing in LnEO concentrations. On the other hand, anesthesia times were decreased with increasing of 2-PE concentrations, while recovery times increased. Induction and recovery times for LnEO were significantly dependent on concentrations and positive relationships were recorded between AD and RF, whereas the relationship was negative in 2-PE. Bay leaf essential oil has not been used as an anesthetic agent in fish until now. Our results showed that LnEO was an effective anesthetic agent with some minor side effects on C. moorii.

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  AtıfScopus2·OpenAlex2

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• MakaleYalnız künye2019Scopus SJRQ4/r/munzur/4845
  THE TOXIC EFFECT OF CADMIUM ON HUMAN ERYTHROCYTES AND NAC'S PROTECTIVE ROLE

  Sahilli, Yeliz Cakir

  The toxic effects cadmium (Cd), which is a heavy metal, on human erythrocytes and protective effects of N-acetyl-L-cysteine (NAC) on lipid peroxidation and antioxidant enzymes were investigated. The effects of 1, 50, 150 mu M doses of cadmium and 1mM NAC on the level of malondialdehyde (MDA) in human erythrocytes and superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) enzyme activities were investigated. When the Cd was applied alone, it was found that MDA level increased in erythrocytes and SOD, CAT and GPx activities decreased. No statistically significant difference was observed when 1mM NAC administered erythrocytes were compared with the control cells. However, the beneficial effect was seen only in administration doses of Cd at the levels of I and 50 mu M and NAC was observed to have a protective effect. As a result, NAC partially reduced the toxic effect caused by Cd on erythrocytes but could not completely prevent it.

  İncele
• MakaleAçık Erişim2019/r/munzur/3768
  THE BRYOPHYTE FLORA OF THE SAMANLI MOUNTAINS (SAKARYA, KOCAELI, YALOVA, BURSA) IN NORTH-WEST TURKEY; [ФЛОРА МХОВ ГОР САМАНЛИ (ОБЛАСТИ САКАРЬЯ, КОДЖАЭЛИ, ЯЛОВА И БУРСА) НА СЕВЕРО-ЗАПАДЕ ТУРЦИИ]

  Gözcü, Merve Can; Uyar, Güray; Ören, Muhammet; Ezer, Tülay; Alataş, Mevlüt

  The present study was performed on the Samanlı Mountains, which is extending from Sakarya province to Yalova province, in North-West Turkey. During this study, eight field trips were organized to the research area at different seasons between the years 2013 and 2016. Throughout these studies, with an examination of 3630 bryophyte specimens collected from 189 stations, together with 2 from Anthocerotophyta (hornworts), 61 from Marchantiophyta (liverworts), 306 from Bryophyta (mosses), in total 369 specific and infraspecific taxa, belonging to 70 families and 156 genera, have been identified. According to grid square system of Turkey which was adopted by Henderson, 68 taxa for A1 square and 24 taxa for A2 square are new records. Among them, Fissidens curvatus Hornsch., Thamnobryum neckeroides (Hook.) E.Lawton, Plagiothecium neckeroideum Schimp. and Riccia beyrichiana Hampe were recorded for the second time in Turkey. In addition, the present paper reports the first records of Cephaloziella massalongi (Spruce) Müll.Frib, which has been classified as rare (R) in the Red data book of European bryophytes, and Scapania scandica (Arnell et H.Buch) Macvicar in Turkey. Some morphological features, the ecological characteristics and the distribution map of the species are given, along with photographs of diagnostic details.

  AtıfScopus2·OpenAlex14

  İncele
• MakaleAçık Erişim2019/r/munzur/3752
  Ghanaian Mangrove Wetland Endophytic Fungus, Penicillium herquei strain BRS2A-AR produces (9Z, 11E)-13-oxooctadeca-9,11-dienoic acid with activity against Trichomonas mobilensis

  Hayibor, Kennedy; Kwain, Samuel; Osei, Enoch; Nartey, Adwoa Padiki; Tetevi, Gilbert Mawuli; Owusu, Kofi Baffour-Awuah; Camas, Mustafa; Camas, Anil Sazak; Kyeremeh, Kwaku

  Sub-Sahara Africa is burdened with a high incidence of parasitic infections, including schistosomiasis, trypanosomiasis, trichomoniasis, and leishmaniasis. Currently, there is a rapid widespread development of resistance to prescription drugs for these neglected diseases. Microbes provide the largest chemical and biological diversity in drug discovery screening programs; therefore, our project seeks to explore microbes in the sub-region for new drugs. The oxylipin (9Z,11E)-13-oxooctadeca-9,11-dienoic acid (1) was isolated from the Ghanaian endophytic fungus, Penicillium herquei strain BRS2A-AR obtained from the leaves of a Laguncularia racemosa tree growing on the banks of the River Butre in the Western Regional wetlands of Ghana. Compound 1 was isolated on reverse phase HPLC at tR of 34.3 minutes. The structure of compound 1 was confirmed by a combination of mass spectrometry, 1D and 2D-NMR techniques. Compound 1 showed minimal antiparasitic activity when tested against Plasmodium falciparum 3d7 (IC50>100µM; aretesunate, IC50 36nm), Trypanosoma brucei brucei (IC50>100µM; Coptis japonica, IC50 8.20µM), Leishmani donovani (IC50>100µM; amphotericin B, IC50 0.32µM) and Leishmania major (IC50>100µM; amphotericin B, IC50 0.31µM). Compound 1 produced IC50 of 44.47µM when tested against Trichomonas mobilensis with metronidazole (IC50 5.20µM) as standard. These results show the potential to further engineer the structure of compound 1 into a potent anti-Trichomonas scaffold.

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  AtıfScopus13·OpenAlex13

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• MakaleAçık Erişim2019Scopus SJRQ3/r/munzur/3747
  Study of the bioaccumulation of UO2 2+ onto the green microalgae botryococcus braunii using response surface methodology

  Celik, Fatih; Aslani, Mahmoud Ali Asker; Can, Safak Seyhaneyildiz

  The bioaccumulation of UO2 2+ (uranyl ion) was investigated by using dry biomass of Botryococcus braunii. Experiments were conducted based on a rotatable central composite design (CCD) and analyzed using response surface methodology (RSM), which was used to optimize the bioaccumulation process. In this goal, the effects of parameters such as initial uranium (VI) concentration, pH, temperature and contact time were studied. The optimum conditions for maximum removal (87%) of UO2 2+ from an aqueous solution were as follows: initial uranium (VI) concentration (55 mg/l), pH (3.6), temperature (46°C) and contact time (74 min). Langmuir and Freundlich isotherms and also thermodynamic parameters like Enthalpy (∆H°), Entropy (∆S°), standard Gibbs free energy (∆G°) were investigated, as well.

  AtıfScopus18·WoS17·OpenAlex8

  İncele
• MakaleYalnız künye2019Scopus SJRQ3/r/munzur/3729
  Anesthetic Efficiency of Three Medicinal Plant Oils for Aquatic Species: Coriander Coriandrum sativum, Linaloe Tree Bursera delpechiana, and Lavender Lavandula hybrida

  Can, Erkan; Kızak, Volkan; Can, Şafak Seyhaneyıldız; Özçiçek, Esin

  This study evaluated the potential of three essential oils (EOs) that were obtained from coriander Coriandrum sativum (CEO), linaloe tree Bursera delpechiana (BEO), and lavender Lavandula hybrida (LEO) as anesthetic agents. Convict Cichlids Amatitlania nigrofasciata (Günther 1867) were exposed to eight concentrations of anesthetic (50, 75, 100, 125, 150, 200, 250, and 300 μL/L). After exposure to the anesthetic, the fish were transferred to clean water to recover. All of the EOs produced an anesthetic effect after exposure to the compounds for 30 min at the minimal effective concentration (MEC), which was identified according to deep anesthesia (A5 < 3 min) and full recovery (R3 < 5 min) times. At 50 and 75 μL/L, the total loss of equilibrium was not observed for all tested EOs. The total loss of reflex was induced at a faster rate with higher concentrations of anesthetic in all groups. The recovery time generally increased as the concentration of the anesthetic increased. These findings suggest that CEO, BEO, and LEO are all novel potential anesthetics for aquaculture, and the optimal concentrations were identified as 150 μL/L (A5; 156 ± 1.7 s and R3; 165 ± 2.9 s), 125 μL/L (A5; 176 ± 3.5 s; R3; 125 ± 2.0 s), and 200 μL/L (A5; 20.1 ± 2.4 s and R3; 162 ± 3.4 s), respectively. When considering the active ingredients of EOs, this study also demonstrated that future studies should be focused on the major components such as linalyl acetate, 1.8-cineole, α-pinene, geraniol, and linalool. Their synergistic effects should be examined in herbal anesthetic treatments, since new commercial anesthetics will likely contain them.

  AtıfScopus17·WoS16·OpenAlex23

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