Metastasis inhibitory role of blueberries: time to play gooseberry with oncogenic cascades and metastasis

The magical little fruits have started to gain attention because of their cancer chemopreventive roles against different cancers. More recently, cancer inhibitory properties of blueberry extracts and isolated bioactive constituents have been described that provide new mechanistic insights. However, there are visible knowledge gaps in our understanding about metastasis inhibitory role of blueberries in xenografted mice. Despite mainstream popularization of cancer chemopreventive role of blueberries, many questions remain about their precise role in the regulation of deregulated oncogenic cascades in metastasis. It will be really exciting to consider how new scientific breakthroughs in future might propel the science of nutrigenomics to a more sophisticated level of inquiry.