Munzur ÜniversitesiMunzur ÜniversitesiAçık Erişim Arşivi · RDL Open

Multifunctional role of Nobiletin in cancer chemoprevention

Derleme MakaleAçık ErişimScopus SJRQ4
  • SDG 3 · Sağlık ve Kaliteli Yaşam

Özet

The diversity of highly bioactive and pharmacologically active natural products which recognize essential biological targets having exquisite specificity, constitutes a massive pharmacological database for discovery of valuable drugs. The rapid accumulation of information has revealed chemopreventive role of nobiletin against wide variety of cancers. Recent efforts are now being expanded and new integrative omics technologies have illuminated continuously upgrading list of molecular mechanisms which underlie carcinogenesis and metastasis. In this mini-review, we explore the progress that has been made in the identification of promising molecular targets of nobiletin.

Anahtar Kelimeler

animal modelsapoptosisCancercell Signaling
RDL Kalıcı Bağlantı (PID)
https://rdlopen.rawdatalibrary.net/r/munzur/2927Resmi atıflarda kullanılan kalıcı adres
DOI
https://doi.org/10.14715/cmb/2022.68.7.33Yayıncı resmi DOI adresi
İndeks kayıtları
ScopusScopusWeb of ScienceWeb of SciencePubMedPubMed
Kaydın indeks veri tabanlarındaki sayfası (aktarımda alınan kayıt numarasıyla). Erişim, indeksin kendi koşullarına bağlıdır.
Atıflar
Scopus
5
OpenAlex
4
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Tam Kayıt
AlanDeğerDil
dc.contributor.authorMalik, Durr-E-Shahwar
dc.contributor.authorAttar, Rukset
dc.contributor.authorOzbey, Ulku
dc.contributor.authorRomero, Mirna Azalea
dc.contributor.authorYulaevna, Ishmuratova Margarita
dc.contributor.authorPurenovic, Jelena
dc.date.accessioned2026-10-28T14:55:59.586715657Z
dc.date.available2026-10-28T14:55:59.586715657Z
dc.date.issued2022
dc.description.abstractThe diversity of highly bioactive and pharmacologically active natural products which recognize essential biological targets having exquisite specificity, constitutes a massive pharmacological database for discovery of valuable drugs. The rapid accumulation of information has revealed chemopreventive role of nobiletin against wide variety of cancers. Recent efforts are now being expanded and new integrative omics technologies have illuminated continuously upgrading list of molecular mechanisms which underlie carcinogenesis and metastasis. In this mini-review, we explore the progress that has been made in the identification of promising molecular targets of nobiletin.
dc.identifier.doi10.14715/cmb/2022.68.7.33
dc.identifier.eissn1165-158X
dc.identifier.endpage207
dc.identifier.issn0145-5680
dc.identifier.issue7
dc.identifier.pmid36495495
dc.identifier.scopus2-s2.0-85143917640
dc.identifier.startpage200
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/munzur/2927
dc.identifier.volume68
dc.identifier.wosWOS:000898196800033
dc.language.isoen
dc.publisherCellular and Molecular Biology Association
dc.relation.ispartofCellular and Molecular Biology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectanimal models
dc.subjectapoptosis
dc.subjectCancer
dc.subjectcell Signaling
dc.subject.otherCarcinogenesis
dc.subject.otherChemoprevention
dc.subject.otherHumans
dc.subject.otherNeoplasms
dc.subject.othercarcinogen
dc.subject.otherimmunoglobulin enhancer binding protein
dc.subject.otherJanus kinase
dc.subject.othermammalian target of rapamycin
dc.subject.othermicroRNA
dc.subject.othernobiletin
dc.subject.otherprotein kinase B
dc.subject.otherSTAT protein
dc.subject.otherAkt signaling
dc.subject.otheranimal model
dc.subject.othercancer prevention
dc.subject.otherdetoxification
dc.subject.otherhuman
dc.subject.otherJAK-STAT signaling
dc.subject.othermalignant neoplasm
dc.subject.othermTOR signaling
dc.subject.othermultiomics
dc.subject.otherNF kB signaling
dc.subject.othernonhuman
dc.subject.otherregulatory mechanism
dc.subject.otherReview
dc.subject.otherchemoprophylaxis
dc.subject.otherneoplasm
dc.titleMultifunctional role of Nobiletin in cancer chemoprevention
dc.typeReview Article
rdl.citation.openalex4
rdl.citation.scopus5
rdl.departmentInstitute of Pharmaceutical Sciences, PUMHSW, Nawabshah, Pakistan
rdl.departmentDepartment of Obstetrics and Gynecology, Yeditepe University, Turkey
rdl.departmentDepartment of Nutrition and Dietetics, Faculty of Health Sciences, Munzur University, Turkey
rdl.departmentFacultad de Medicina, Universidad Autónoma de Guerrero, Laboratorio de Investigación Clínica, Av. Solidaridad S/N, Colonia Hornos Insurgentes, cp 39300, Acapulco, Guerrero México
rdl.departmentE. A. Buketov Karaganda University, Kazakhstan
rdl.departmentFaculty of Technical Sciences, Cacak University of Kragujevac, Cacak, Serbia
rdl.oa.statushybrid
rdl.oa.statusclosed
rdl.oa.urlhttps://cellmolbiol.org/index.php/CMB/article/download/4482/2231
rdl.scopus.quartileQ4
rdl.sdgSDG03
rdl.source.indexSCOPUS
rdl.source.indexWOS
rdl.source.indexPUBMED