Convolutional neural networks for multi-class brain disease detection using MRI images

MakaleAçık ErişimScopus SJRQ1
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Özet

The brain disorders may cause loss of some critical functions such as thinking, speech, and movement. So, the early detection of brain diseases may help to get the timely best treatment. One of the conventional methods used to diagnose these disorders is the magnetic resonance imaging (MRI) technique. Manual diagnosis of brain abnormalities is time-consuming and difficult to perceive the minute changes in the MRI images, especially in the early stages of abnormalities. Proper selection of the features and classifiers to obtain the highest performance is a challenging task. Hence, deep learning models have been widely used for medical image analysis over the past few years. In this study, we have employed the AlexNet, Vgg-16, ResNet-18, ResNet-34, and ResNet-50 pre-trained models to automatically classify MR images in to normal, cerebrovascular, neoplastic, degenerative, and inflammatory diseases classes. We have also compared their classification performance with pre-trained models, which are the state-of-art architectures. We have obtained the best classification accuracy of 95.23% ± 0.6 with the ResNet-50 model among the five pre-trained models. Our model is ready to be tested with huge MRI images of brain abnormalities. The outcome of the model will also help the clinicians to validate their findings after manual reading of the MRI images.

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AlanDeğerDil
dc.contributor.authorTalo, Muhammed
dc.contributor.authorYildirim, Ozal
dc.contributor.authorBaloglu, Ulas Baran
dc.contributor.authorAydin, Galip
dc.contributor.authorAcharya, U Rajendra
dc.date.accessioned2026-10-28T14:56:37.019208931Z
dc.date.available2026-10-28T14:56:37.019208931Z
dc.date.issued2019
dc.description.abstractThe brain disorders may cause loss of some critical functions such as thinking, speech, and movement. So, the early detection of brain diseases may help to get the timely best treatment. One of the conventional methods used to diagnose these disorders is the magnetic resonance imaging (MRI) technique. Manual diagnosis of brain abnormalities is time-consuming and difficult to perceive the minute changes in the MRI images, especially in the early stages of abnormalities. Proper selection of the features and classifiers to obtain the highest performance is a challenging task. Hence, deep learning models have been widely used for medical image analysis over the past few years. In this study, we have employed the AlexNet, Vgg-16, ResNet-18, ResNet-34, and ResNet-50 pre-trained models to automatically classify MR images in to normal, cerebrovascular, neoplastic, degenerative, and inflammatory diseases classes. We have also compared their classification performance with pre-trained models, which are the state-of-art architectures. We have obtained the best classification accuracy of 95.23% ± 0.6 with the ResNet-50 model among the five pre-trained models. Our model is ready to be tested with huge MRI images of brain abnormalities. The outcome of the model will also help the clinicians to validate their findings after manual reading of the MRI images.
dc.identifier.articlenumber101673
dc.identifier.doi10.1016/j.compmedimag.2019.101673
dc.identifier.eissn1879-0771
dc.identifier.issn0895-6111
dc.identifier.pmid31635910
dc.identifier.scopus2-s2.0-85073821519
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/munzur/3421
dc.identifier.volume78
dc.identifier.wosWOS:000501660500002
dc.language.isoen
dc.publisherElsevier Ltd
dc.relation.ispartofComputerized Medical Imaging and Graphics
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBrain disease
dc.subjectCNN
dc.subjectDeep transfer learning
dc.subjectMRI classification
dc.subjectResNet
dc.subject.otherBrain Diseases
dc.subject.otherDatasets as Topic
dc.subject.otherDeep Learning
dc.subject.otherEarly Diagnosis
dc.subject.otherHumans
dc.subject.otherMagnetic Resonance Imaging
dc.subject.otherNeural Networks, Computer
dc.subject.otherDiagnosis
dc.subject.otherDiseases
dc.subject.otherMedical imaging
dc.subject.otherNeural networks
dc.subject.otherBrain disease
dc.subject.otherClassification accuracy
dc.subject.otherClassification performance
dc.subject.otherConventional methods
dc.subject.otherConvolutional neural network
dc.subject.otherInflammatory disease
dc.subject.otherResNet
dc.subject.otherTransfer learning
dc.subject.otherArticle
dc.subject.otherback propagation
dc.subject.otherback propagation neural network
dc.subject.otherclassification algorithm
dc.subject.otherdiscrete wavelet transform
dc.subject.otherdisease classification
dc.subject.otherhuman
dc.subject.otherimage analysis
dc.subject.otherneuroimaging
dc.subject.othernuclear magnetic resonance imaging
dc.subject.otheroutcome assessment
dc.subject.otherpriority journal
dc.subject.othertransfer of learning
dc.subject.otherclassification
dc.subject.otherdiagnostic imaging
dc.subject.otherinformation processing
dc.titleConvolutional neural networks for multi-class brain disease detection using MRI images
dc.typeArticle
rdl.citation.openalex301
rdl.citation.scopus276
rdl.departmentDepartment of Computer Engineering, Munzur University, Tunceli, Turkey
rdl.departmentDepartment of Computer Science, University of Bristol, Bristol, UK
rdl.departmentDepartment of Computer Engineering, Fırat University, Elazığ, Turkey
rdl.departmentDepartment of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore
rdl.departmentDepartment of Biomedical Engineering, School of Science and Technology, Singapore School of Social Sciences, Singapore
rdl.departmentInternational Research Organization for Advanced Science and Technology (IROAST), Kumamoto University, Kumamoto, Japan
rdl.oa.statusgreen
rdl.oa.statusclosed
rdl.oa.urlhttps://hdl.handle.net/11508/62059
rdl.scopus.quartileQ1
rdl.sdgSDG03
rdl.source.indexSCOPUS
rdl.source.indexWOS
rdl.source.indexPUBMED