Automated detection of COVID-19 cases using deep neural networks with X-ray images

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Özet

The novel coronavirus 2019 (COVID-2019), which first appeared in Wuhan city of China in December 2019, spread rapidly around the world and became a pandemic. It has caused a devastating effect on both daily lives, public health, and the global economy. It is critical to detect the positive cases as early as possible so as to prevent the further spread of this epidemic and to quickly treat affected patients. The need for auxiliary diagnostic tools has increased as there are no accurate automated toolkits available. Recent findings obtained using radiology imaging techniques suggest that such images contain salient information about the COVID-19 virus. Application of advanced artificial intelligence (AI) techniques coupled with radiological imaging can be helpful for the accurate detection of this disease, and can also be assistive to overcome the problem of a lack of specialized physicians in remote villages. In this study, a new model for automatic COVID-19 detection using raw chest X-ray images is presented. The proposed model is developed to provide accurate diagnostics for binary classification (COVID vs. No-Findings) and multi-class classification (COVID vs. No-Findings vs. Pneumonia). Our model produced a classification accuracy of 98.08% for binary classes and 87.02% for multi-class cases. The DarkNet model was used in our study as a classifier for the you only look once (YOLO) real time object detection system. We implemented 17 convolutional layers and introduced different filtering on each layer. Our model (available at (https://github.com/muhammedtalo/COVID-19)) can be employed to assist radiologists in validating their initial screening, and can also be employed via cloud to immediately screen patients.

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AlanDeğerDil
dc.contributor.authorOzturk, Tulin
dc.contributor.authorTalo, Muhammed
dc.contributor.authorYildirim, Eylul Azra
dc.contributor.authorBaloglu, Ulas Baran
dc.contributor.authorYildirim, Ozal
dc.contributor.authorRajendra Acharya, U.
dc.date.accessioned2026-10-28T14:56:46.597359724Z
dc.date.available2026-10-28T14:56:46.597359724Z
dc.date.issued2020
dc.description.abstractThe novel coronavirus 2019 (COVID-2019), which first appeared in Wuhan city of China in December 2019, spread rapidly around the world and became a pandemic. It has caused a devastating effect on both daily lives, public health, and the global economy. It is critical to detect the positive cases as early as possible so as to prevent the further spread of this epidemic and to quickly treat affected patients. The need for auxiliary diagnostic tools has increased as there are no accurate automated toolkits available. Recent findings obtained using radiology imaging techniques suggest that such images contain salient information about the COVID-19 virus. Application of advanced artificial intelligence (AI) techniques coupled with radiological imaging can be helpful for the accurate detection of this disease, and can also be assistive to overcome the problem of a lack of specialized physicians in remote villages. In this study, a new model for automatic COVID-19 detection using raw chest X-ray images is presented. The proposed model is developed to provide accurate diagnostics for binary classification (COVID vs. No-Findings) and multi-class classification (COVID vs. No-Findings vs. Pneumonia). Our model produced a classification accuracy of 98.08% for binary classes and 87.02% for multi-class cases. The DarkNet model was used in our study as a classifier for the you only look once (YOLO) real time object detection system. We implemented 17 convolutional layers and introduced different filtering on each layer. Our model (available at (https://github.com/muhammedtalo/COVID-19)) can be employed to assist radiologists in validating their initial screening, and can also be employed via cloud to immediately screen patients.
dc.identifier.articlenumber103792
dc.identifier.doi10.1016/j.compbiomed.2020.103792
dc.identifier.eissn1879-0534
dc.identifier.issn0010-4825
dc.identifier.pmcidPMC7187882
dc.identifier.pmid32568675
dc.identifier.scopus2-s2.0-85083900518
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/munzur/3545
dc.identifier.volume121
dc.identifier.wosWOS:000542187300014
dc.language.isoen
dc.publisherElsevier Ltd
dc.relation.ispartofComputers in Biology and Medicine
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectChest X-ray images
dc.subjectCoronavirus (COVID-19)
dc.subjectDeep learning
dc.subjectRadiology images
dc.subject.otherBetacoronavirus
dc.subject.otherComputational Biology
dc.subject.otherCoronavirus Infections
dc.subject.otherDatabases, Factual
dc.subject.otherDeep Learning
dc.subject.otherDiagnosis, Computer-Assisted
dc.subject.otherFemale
dc.subject.otherHumans
dc.subject.otherLung
dc.subject.otherMale
dc.subject.otherMiddle Aged
dc.subject.otherNeural Networks, Computer
dc.subject.otherPandemics
dc.subject.otherPneumonia
dc.subject.otherPneumonia, Viral
dc.subject.otherRadiographic Image Interpretation, Computer-Assisted
dc.subject.otherDiagnosis
dc.subject.otherImaging techniques
dc.subject.otherObject detection
dc.subject.otherViruses
dc.subject.otherAutomated detection
dc.subject.otherBinary classification
dc.subject.otherChest X-ray image
dc.subject.otherClassification accuracy
dc.subject.otherDevastating effects
dc.subject.otherMulti-class classification
dc.subject.otherObject detection systems
dc.subject.otherRadiological imaging
dc.subject.otheradult
dc.subject.otheradult respiratory distress syndrome
dc.subject.otherArticle
dc.subject.otherartificial intelligence
dc.subject.othercomputer assisted diagnosis
dc.subject.othercoronavirus disease 2019
dc.subject.otherdeep neural network
dc.subject.otherdiagnostic test accuracy study
dc.subject.otherdisease classification
dc.subject.otherfeature extraction
dc.subject.otherhuman
dc.subject.othermajor clinical study
dc.subject.othermulticlass classification
dc.subject.otherpriority journal
dc.subject.othersensitivity and specificity
dc.subject.otherSevere acute respiratory syndrome coronavirus 2
dc.subject.otherthorax radiography
dc.subject.othervirus pneumonia
dc.subject.otherbiology
dc.subject.otherclassification
dc.subject.otherCoronavirus infection
dc.subject.otherdiagnostic imaging
dc.subject.otherfactual database
dc.subject.otherpandemic
dc.subject.otherDeep neural networks
dc.titleAutomated detection of COVID-19 cases using deep neural networks with X-ray images
dc.typeArticle
rdl.citation.openalex2595
rdl.citation.scopus2286
rdl.departmentDepartment of Radiology, Medikal Park Hospital, Elazığ, Turkey
rdl.departmentDepartment of Software Engineering, Firat University, Elazig, Turkey
rdl.departmentComputer Engineer, Ministry of Health, Ankara, Turkey
rdl.departmentDepartment of Computer Engineering, University of Bristol, Bristol, UK
rdl.departmentDepartment of Computer Engineering, Munzur University, Tunceli, Turkey
rdl.departmentDepartment of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore
rdl.departmentDepartment of Bioinformatics and Medical Engineering, Asia University, Taichung, Taiwan
rdl.departmentInternational Research Organization for Advanced Science and Technology (IROAST), Kumamoto University, Kumamoto, Japan
rdl.oa.statusgreen
rdl.oa.statusclosed
rdl.oa.urlhttps://www.ncbi.nlm.nih.gov/pmc/articles/7187882
rdl.scopus.quartileQ1
rdl.sdgSDG03
rdl.source.indexSCOPUS
rdl.source.indexWOS
rdl.source.indexPUBMED