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Maslinic acid as an effective anticancer agent

MakaleAçık ErişimScopus SJRQ3
  • SDG 3 · Sağlık ve Kaliteli Yaşam

Özet

Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.

Anahtar Kelimeler

ApoptosisCancerMaslinic acidSignaling
RDL Kalıcı Bağlantı (PID)
https://rdlopen.rawdatalibrary.net/r/munzur/3565Resmi atıflarda kullanılan kalıcı adres
DOI
https://doi.org/10.14715/cmb/2018.64.10.14Yayıncı resmi DOI adresi
İndeks kayıtları
ScopusScopusWeb of ScienceWeb of SciencePubMedPubMed
Kaydın indeks veri tabanlarındaki sayfası (aktarımda alınan kayıt numarasıyla). Erişim, indeksin kendi koşullarına bağlıdır.
Atıflar
Scopus
20
OpenAlex
17
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Tam Kayıt
AlanDeğerDil
dc.contributor.authorLin, Xiukun
dc.contributor.authorOzbey, Ulku
dc.contributor.authorUteuliyev, Yerzhan Sabitaliyevich
dc.contributor.authorAttar, Rukset
dc.contributor.authorOzcelik, Beraat
dc.contributor.authorZhang, Yuanyan
dc.contributor.authorGuo, Mingyue
dc.contributor.authorLiu, Minghua
dc.contributor.authorAlhewairini, Saleh S.
dc.contributor.authorFarooqi, Ammad Ahmad
dc.date.accessioned2026-10-28T14:56:48.191695087Z
dc.date.available2026-10-28T14:56:48.191695087Z
dc.date.issued2018
dc.description.abstractMaslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.
dc.identifier.doi10.14715/cmb/2018.64.10.14
dc.identifier.eissn1165-158X
dc.identifier.endpage91
dc.identifier.issn0145-5680
dc.identifier.issue10
dc.identifier.pmid30084808
dc.identifier.scopus2-s2.0-85051815468
dc.identifier.startpage87
dc.identifier.urihttps://rdlopen.rawdatalibrary.net/r/munzur/3565
dc.identifier.volume64
dc.identifier.wosWOS:000443253900014
dc.language.isoen
dc.publisherCellular and Molecular Biology Association
dc.relation.ispartofCellular and Molecular Biology
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectApoptosis
dc.subjectCancer
dc.subjectMaslinic acid
dc.subjectSignaling
dc.subject.otherAnimals
dc.subject.otherAnticarcinogenic Agents
dc.subject.otherAntineoplastic Agents
dc.subject.otherApoptosis
dc.subject.otherGene Expression Regulation, Neoplastic
dc.subject.otherHumans
dc.subject.otherMicroRNAs
dc.subject.otherNeoplasms
dc.subject.otherProtein Interaction Maps
dc.subject.otherSignal Transduction
dc.subject.otherTriterpenes
dc.subject.otherantineoplastic agent
dc.subject.otherimmunoglobulin enhancer binding protein
dc.subject.othermaslinic acid
dc.subject.othermicroRNA
dc.subject.othertriterpene
dc.subject.otherantineoplastic activity
dc.subject.otherArticle
dc.subject.othercolon cancer
dc.subject.otherdrug bioavailability
dc.subject.othergallbladder cancer
dc.subject.othergene targeting
dc.subject.otherhuman
dc.subject.otherlung cancer
dc.subject.othernonhuman
dc.subject.otherpancreas cancer
dc.subject.otherprostate cancer
dc.subject.otherprotein targeting
dc.subject.otherstomach cancer
dc.subject.otheranimal
dc.subject.otherdrug effect
dc.subject.othergene expression regulation
dc.subject.othergenetics
dc.subject.othermetabolism
dc.subject.otherneoplasm
dc.subject.otherprotein analysis
dc.titleMaslinic acid as an effective anticancer agent
dc.typeArticle
rdl.citation.openalex17
rdl.citation.scopus20
rdl.departmentDepartment of Pharmacology, Southwest Medical Univerisity, Luzhou, Sichuan 646000, China
rdl.departmentDepartment of Genetics, Health High School, Munzur University, 62000, Tunceli, Turkey
rdl.departmentKazakhstan Medical University "KSPH", Kazakhstan
rdl.departmentDepartment of Obstetrics and Gynecology, Yeditepe University, Turkey
rdl.departmentFood Engineering Department, Istanbul Technical University, Maslak, 34469, Istanbul, Turkey
rdl.departmentDepartment of Plant Production and Protection, College of Agriculture and Veterinary Medicine, Qassim University, P.O. Box 6622, Buraidah 51452, Al-Qassim, Saudi Arabia
rdl.departmentInstitute of Biomedical and genetic Engineering (IBGE), Islamabad, Pakistan
rdl.oa.statushybrid
rdl.oa.statusclosed
rdl.oa.urlhttps://doi.org/10.14715/cmb/2018.64.10.14
rdl.scopus.quartileQ3
rdl.sdgSDG03
rdl.source.indexSCOPUS
rdl.source.indexWOS
rdl.source.indexPUBMED