Antibacterial and Antifungal Features of Centaurea urvillei DC. subsp. urvillei that is herboized in Turkey

Although there are many studies on the activities of different species, the compounds and effects of Centaurea L., the largest genus of the Turkish flora, on human health, no relevant studies have been conducted on the antimicrobial properties of the usable parts (above ground leaves, flowers) of C. urvillei DC. subsp urvillei against pathogenic microorganisms.This study aimed to show whether it prevents the growth of these microorganisms that cause infectious diseases in humans on bacteria, yeast, dermatophytes that cause infectious diseases in humans via well agar and microdilution method by applying a methanol solution of the usable parts of C. urvillei DC. subsp. urvillei. Regarding the antimicrobial susceptibility results, the plant solution formed a generally sensitive inhibition zone (14.66 mm-11.66 mm inhibition zone-1 diameter) on inhibition of growth of yeast, dermatophyte isolates and other bacteria. This means that 40 mg dose of C. urvillei DC. subsp. urvillei has antibacterial and antifungal that can prevent the growth of all test microorganisms (Escherichia coli ATCC 25922, Staphylococcus aureus ATCC 29213, Enterococcus faecalis ATCC 29212, Klepsiella pneumoniae clinical isolate, Candida albicans RSKK 02007, Candida glabrata RSKK 014019, Candida tropicalis RSKK 02011, Epidermophyton floccosum RSKK 14024, Trichophyton rubrum RSKK 03022) that cause disease. It is seen when we compared with the control group that there was no significant difference in bacteria, however, a significant difference was observed in yeast and dermatophytes (p