Sürdürülebilir Kalkınma Amaçları
Yayınlar
- BildiriAçık Erişim2021Deep Neural Network Trained on Surface ECG Improves Diagnostic Accuracy of Prior Myocardial Infarction over Q Wave Analysis
Yildirim, Ozal; Baloglu, Ulas B; Talo, Muhammed; Ganesan, Prasanth; Tung, Jagteshwar S; Kang, Guson; Tooley, James; Alhusseini, Mahmood I.; Baykaner, Tina; Wang, Paul J.
Clinical screening of myocardial infarction is important for preventative treatment and risk stratification in cardiology practice, however current detection by electrocardiogram Q-wave analysis provides only modest accuracy for assessing prior cardiac events. We set out to evaluate the ability of a deep neural network trained on the electrocardiogram to identify patients with clinical history of myocardial infarction. We assessed 608 patients at two academic centers with adjudicated history of myocardial infarction. Surface electrocardiograms were used to train a neural network-based model that classifies patients with and without a history of infarction. Endpoints were assessed by clinical record review and accuracy of the model was compared against the manual assessment of pathologic Q waves. The neural network outperformed the accuracy of pathologic Q waves (62%). In training, the model accuracy converged to >98%. Validation was performed by cross-validation (k=5) with validation accuracy 71 ± 5%. Receiver-operator characteristics analysis resulted in a c-statistic of 0.730. Deep learning of a 12-lead ECG can identify features of prior myocardial injury more accurately than clinical Q-wave analysis and may serve as a valuable clinical screening tool.
AtıfScopus3OpenAlex3
İncele - MakaleAçık Erişim2020Scopus SJRQ11D-CADCapsNet: One dimensional deep capsule networks for coronary artery disease detection using ECG signals
Butun, Ertan; Yildirim, Ozal; Talo, Muhammed; Tan, Ru-San; Rajendra Acharya, U.
Purpose: Cardiovascular disease (CVD) is a leading cause of death globally. Electrocardiogram (ECG), which records the electrical activity of the heart, has been used for the diagnosis of CVD. The automated and robust detection of CVD from ECG signals plays a significant role for early and accurate clinical diagnosis. The purpose of this study is to provide automated detection of coronary artery disease (CAD) from ECG signals using capsule networks (CapsNet). Methods: Deep learning-based approaches have become increasingly popular in computer aided diagnosis systems. Capsule networks are one of the new promising approaches in the field of deep learning. In this study, we used 1D version of CapsNet for the automated detection of coronary artery disease (CAD) on two second (95,300) and five second-long (38,120) ECG segments. These segments are obtained from 40 normal and 7 CAD subjects. In the experimental studies, 5-fold cross validation technique is employed to evaluate performance of the model. Results: The proposed model, which is named as 1D-CADCapsNet, yielded a promising 5-fold diagnosis accuracy of 99.44% and 98.62% for two- and five-second ECG signal groups, respectively. We have obtained the highest performance results using 2 s ECG segment than the state-of-art studies reported in the literature. Conclusions: 1D-CADCapsNet model automatically learns the pertinent representations from raw ECG data without using any hand-crafted technique and can be used as a fast and accurate diagnostic tool to help cardiologists.
AtıfScopus100OpenAlex96
İncele - MakaleAçık Erişim2020Scopus SJRQ1Automated detection of COVID-19 cases using deep neural networks with X-ray images
Ozturk, Tulin; Talo, Muhammed; Yildirim, Eylul Azra; Baloglu, Ulas Baran; Yildirim, Ozal; Rajendra Acharya, U.
The novel coronavirus 2019 (COVID-2019), which first appeared in Wuhan city of China in December 2019, spread rapidly around the world and became a pandemic. It has caused a devastating effect on both daily lives, public health, and the global economy. It is critical to detect the positive cases as early as possible so as to prevent the further spread of this epidemic and to quickly treat affected patients. The need for auxiliary diagnostic tools has increased as there are no accurate automated toolkits available. Recent findings obtained using radiology imaging techniques suggest that such images contain salient information about the COVID-19 virus. Application of advanced artificial intelligence (AI) techniques coupled with radiological imaging can be helpful for the accurate detection of this disease, and can also be assistive to overcome the problem of a lack of specialized physicians in remote villages. In this study, a new model for automatic COVID-19 detection using raw chest X-ray images is presented. The proposed model is developed to provide accurate diagnostics for binary classification (COVID vs. No-Findings) and multi-class classification (COVID vs. No-Findings vs. Pneumonia). Our model produced a classification accuracy of 98.08% for binary classes and 87.02% for multi-class cases. The DarkNet model was used in our study as a classifier for the you only look once (YOLO) real time object detection system. We implemented 17 convolutional layers and introduced different filtering on each layer. Our model (available at (https://github.com/muhammedtalo/COVID-19)) can be employed to assist radiologists in validating their initial screening, and can also be employed via cloud to immediately screen patients.
AtıfScopus2286OpenAlex2595İncele - MakaleAçık Erişim2020Scopus SJRQ1Automated invasive ductal carcinoma detection based using deep transfer learning with whole-slide images
Celik, Yusuf; Talo, Muhammed; Yildirim, Ozal; Karabatak, Murat; Acharya, U Rajendra
Advances in artificial intelligence technologies have made it possible to obtain more accurate and reliable results using digital images. Due to the advances in digital histopathological images obtained using whole slide image (WSI) scanners, automated analysis of digital images by computer support systems has become interesting. In particular, deep learning architectures, are one of the preferred approaches in the analysis of digital histopathology images. The deeper networks trained on large amounts of image data are adapted for different tasks using transfer learning technique. In this study, automated detection of invasive ductal carcinoma (IDC), which is the most common subtype of breast cancers, is proposed using deep transfer learning technique. We have used deep learning pre-trained models, ResNet-50 and DenseNet-161 for the IDC detection task. The public histopathology dataset containing 277,524 image patches were used in our experimental studies. As a result of training on the last layers of pre-trained deep networks, DenseNet-161 model has yielded F-sore of 92.38% and balanced accuracy value of 91.57%. Similarly, we have obtained F-score of 94.11% and balanced accuracy value of 90.96% using ResNet-50 architecture. In addition, our developed model is validated using the publicly available BreakHis breast cancer dataset and obtained promising results in classifying magnification independent histopathology images into benign and malignant classes. Our developed system obtained the highest classification performance as compared to the state-of-art techniques and is ready to be tested with more diverse huge databases.
AtıfScopus297OpenAlex318İncele - MakaleAçık Erişim2020Scopus SJRQ1Accurate deep neural network model to detect cardiac arrhythmia on more than 10,000 individual subject ECG records
Yildirim, Ozal; Talo, Muhammed; Ciaccio, Edward J.; Tan, Ru San; Acharya, U Rajendra
Background and objective: Cardiac arrhythmia, which is an abnormal heart rhythm, is a common clinical problem in cardiology. Detection of arrhythmia on an extended duration electrocardiogram (ECG) is done based on initial algorithmic software screening, with final visual validation by cardiologists. It is a time consuming and subjective process. Therefore, fully automated computer-assisted detection systems with a high degree of accuracy have an essential role in this task. In this study, we proposed an effective deep neural network (DNN) model to detect different rhythm classes from a new ECG database. Methods: Our DNN model was designed for high performance on all ECG leads. The proposed model, which included both representation learning and sequence learning tasks, showed promising results on all 12-lead inputs. Convolutional layers and sub-sampling layers were used in the representation learning phase. The sequence learning part involved a long short-term memory (LSTM) unit after representation of learning layers. Results: We performed two different class scenarios, including reduced rhythms (seven rhythm types) and merged rhythms (four rhythm types) according to the records from the database. Our trained DNN model achieved 92.24% and 96.13% accuracies for the reduced and merged rhythm classes, respectively. Conclusion: Recently, deep learning algorithms have been found to be useful because of their high performance. The main challenge is the scarcity of appropriate training and testing resources because model performance is dependent on the quality and quantity of case samples. In this study, we used a new public arrhythmia database comprising more than 10,000 records. We constructed an efficient DNN model for automated detection of arrhythmia using these records.
AtıfScopus143OpenAlex146İncele - Derleme MakaleYayıncıda açık erişim2020Scopus SJRQ1Application of deep learning techniques for heartbeats detection using ECG signals-analysis and review
Murat, Fatma; Yildirim, Ozal; Talo, Muhammed; Baloglu, Ulas Baran; Demir, Yakup; Acharya, U. Rajendra
Deep learning models have become a popular mode to classify electrocardiogram (ECG) data. Investigators have used a variety of deep learning techniques for this application. Herein, a detailed examination of deep learning methods for ECG arrhythmia detection is provided. Approaches used by investigators are examined, and their contributions to the field are detailed. For this purpose, journal papers have been surveyed according to the methods used. In addition, various deep learning models and experimental studies are described and discussed. A five-class ECG dataset containing 100,022 beats was then utilized for further analysis of deep learning techniques. The constructed models were examined with this dataset, and results are presented. This study therefore provides information concerning deep learning approaches used for arrhythmia classification, and suggestions for further research in this area.
AtıfScopus318OpenAlex328İncele - MakaleYalnız künye2019Meme Kanseri Histopatolojik Görüntülerinin Evrişimsel Sinir Ağları ile Sınıflandırılması
Talo, Muhammed
Meme kanseri, dünya çapında kadınlar arasında en fazla ölümün görüldüğü kanser türüdür. Meme kanseri imgelerininbilgisayar destekli sistemler yardımıyla hızlı ve doğru bir şekilde sınıflandırılması hayati önem arz etmektedir. Bu çalışmada,meme kanseri imgelerini iyi ve kötü huylu olarak sınıflandırmak için ResNet-50 mimarisi önerilmiştir. Evrişimsel Sinir Ağıtabanlı ResNet-50 mimarisi kullanılarak, açık kaynak BreakHis veri setindeki, meme kanseri imgelerinin ikili sınıflandırılmasıgerçekleştirilmiştir. ResNet-50 mimarisinin eğitiminde transfer öğrenme yöntemi uygulanmıştır. Önerilen modelinsınıflandırma başarısının, literatürdeki mevcut çalışmalara kıyasla daha yüksek olduğu gözlemlenmiştir. Ayrıca önerilen model, meme kanseri imgeleri üzerinde herhangi bir ön işleme yapmadan verileri otomatik olarak sınıflandırmaktadır.
AtıfTR Dizin2
İncele - BildiriYalnız künye2019Pneumonia Detection from Radiography Images using Convolutional Neural Networks
Talo, Muhammed
Pneumonia continues to be the leading cause of child mortality in children under the age of five, and 2,400 children, most of whom are babies under 2 years of age, die from pneumonia. In this study, an automated detection system is proposed for the diagnosis of pneumonia with chest radiography images. With the transfer learning technique, ResNet-152 convolutional neural network was customized to recognize pneumonia from radiography images. With this customized architecture, a recognition success of 97.4% was obtained in the detection of pneumonia disease without any preprocessing of raw data or manual feature extraction on radiography images. This model, which was proposed for the detection of pneumonia, found to be more successful when compared with the other successful studies in the literature.
AtıfWoS6OpenAlex16İncele - MakaleYalnız künye2019Scopus SJRQ1Classification of myocardial infarction with multi-lead ECG signals and deep CNN
Baloglu, Ulas Baran; Talo, Muhammed; Yildirim, Ozal; Tan, Ru San; Acharya, U Rajendra
Myocardial infarction (MI), commonly known as heart attack, causes irreversible damage to heart muscles and even leads to death. Rapid and accurate diagnosis of MI is critical to avoid death. Blood tests and electrocardiogram (ECG) signals are used to diagnose acute MI. However, for an increase in blood enzyme values, a certain time must pass after the attack. This time lag may delay MI diagnosis. Hence, ECG diagnosis is still very important. Manual ECG interpretation requires expertise and is prone to inter-observer variability. Therefore, computer aided diagnosis may be useful in automatic detection of MI on ECG. In this study, a deep learning model with an end-to-end structure on the standard 12-lead ECG signal for the diagnosis of MI is proposed. For this purpose, the most commonly used technique, convolutional neural network (CNN) is used. Our trained CNN model with the proposed architecture yielded impressive accuracy and sensitivity performance over 99.00% for MI diagnosis on all ECG lead signals. Thus, the proposed model has the potential to provide high performance on MI detection which can be used in wearable technologies and intensive care units.
AtıfScopus457OpenAlex476İncele - MakaleYalnız künye2019Scopus SJRQ3Application of deep transfer learning for automated brain abnormality classification using MR images
Talo, Muhammed; Baloglu, Ulas Baran; Yıldırım, Özal; Rajendra Acharya, U.
Magnetic resonance imaging (MRI) is the most common imaging technique used to detect abnormal brain tumors. Traditionally, MRI images are analyzed manually by radiologists to detect the abnormal conditions in the brain. Manual interpretation of huge volume of images is time consuming and difficult. Hence, computer-based detection helps in accurate and fast diagnosis. In this study, we proposed an approach that uses deep transfer learning to automatically classify normal and abnormal brain MR images. Convolutional neural network (CNN) based ResNet34 model is used as a deep learning model. We have used current deep learning techniques such as data augmentation, optimal learning rate finder and fine-tuning to train the model. The proposed model achieved 5-fold classification accuracy of 100% on 613 MR images. Our developed system is ready to test on huge database and can assist the radiologists in their daily screening of MR images.
AtıfScopus473OpenAlex508İncele - BildiriAçık Erişim2019Bigailab-4race-50K: Race Classification with a New Benchmark Dataset
Talo, Muhammed; Ay, Betul; Makinist, Semiha; Aydin, Galip
Face analysis is the process of extracting useful information such as gender, age and race from a face image. In this study, we look at ways of closing the gap between the capabilities of automatic facial recognition and race classification methods. For this purpose, we take the following two steps. (1) We offer a public race dataset consisting of labeled images to overcome the challenges of real-world race estimation tasks. (2) We present a benchmark study to find race of a human face using a pre-trained Convolutional Neural Network (CNN) model on the large-scale face dataset. We are able to achieve a remarkable accuracy of 97.6% in race classification task.
AtıfScopus3OpenAlex5İncele - MakaleAçık Erişim2019Scopus SJRQ1Convolutional neural networks for multi-class brain disease detection using MRI images
Talo, Muhammed; Yildirim, Ozal; Baloglu, Ulas Baran; Aydin, Galip; Acharya, U Rajendra
The brain disorders may cause loss of some critical functions such as thinking, speech, and movement. So, the early detection of brain diseases may help to get the timely best treatment. One of the conventional methods used to diagnose these disorders is the magnetic resonance imaging (MRI) technique. Manual diagnosis of brain abnormalities is time-consuming and difficult to perceive the minute changes in the MRI images, especially in the early stages of abnormalities. Proper selection of the features and classifiers to obtain the highest performance is a challenging task. Hence, deep learning models have been widely used for medical image analysis over the past few years. In this study, we have employed the AlexNet, Vgg-16, ResNet-18, ResNet-34, and ResNet-50 pre-trained models to automatically classify MR images in to normal, cerebrovascular, neoplastic, degenerative, and inflammatory diseases classes. We have also compared their classification performance with pre-trained models, which are the state-of-art architectures. We have obtained the best classification accuracy of 95.23% ± 0.6 with the ResNet-50 model among the five pre-trained models. Our model is ready to be tested with huge MRI images of brain abnormalities. The outcome of the model will also help the clinicians to validate their findings after manual reading of the MRI images.
AtıfScopus276OpenAlex301İncele - MakaleAçık Erişim2019Scopus SJRQ2Automated detection of diabetic subject using pre-trained 2D-CNN models with frequency spectrum images extracted from heart rate signals
Yildirim, Ozal; Talo, Muhammed; Ay, B.; Baloglu, Ulas Baran; Aydin, G.; Acharya, U. Rajendra
In this study, a deep-transfer learning approach is proposed for the automated diagnosis of diabetes mellitus (DM), using heart rate (HR) signals obtained from electrocardiogram (ECG) data. Recent progress in deep learning has contributed significantly to improvement in the quality of healthcare. In order for deep learning models to perform well, large datasets are required for training. However, a difficulty in the biomedical field is the lack of clinical data with expert annotation. A recent, commonly implemented technique to train deep learning models using small datasets is to transfer the weighting, developed from a large dataset, to the current model. This deep learning transfer strategy is generally employed for two-dimensional signals. Herein, the weighting of models pre-trained using two-dimensional large image data was applied to one-dimensional HR signals. The one-dimensional HR signals were then converted into frequency spectrum images, which were utilized for application to well-known pre-trained models, specifically: AlexNet, VggNet, ResNet, and DenseNet. The DenseNet pre-trained model yielded the highest classification average accuracy of 97.62%, and sensitivity of 100%, to detect DM subjects via HR signal recordings. In the future, we intend to further test this developed model by utilizing additional data along with cloud-based storage to diagnose DM via heart signal analysis.
AtıfScopus145OpenAlex152İncele - MakaleAçık Erişim2019Scopus SJRQ2Automated Depression Detection Using Deep Representation and Sequence Learning with EEG Signals
Ay, Betul; Yildirim, Ozal; Talo, Muhammed; Baloglu, Ulas Baran; Aydin, Galip; Puthankattil, Subha D.; Acharya, U. Rajendra
Depression affects large number of people across the world today and it is considered as the global problem. It is a mood disorder which can be detected using electroencephalogram (EEG) signals. The manual detection of depression by analyzing the EEG signals requires lot of experience, tedious and time consuming. Hence, a fully automated depression diagnosis system developed using EEG signals will help the clinicians. Therefore, we propose a deep hybrid model developed using convolutional neural network (CNN) and long-short term memory (LSTM) architectures to detect depression using EEG signals. In the deep model, temporal properties of the signals are learned with CNN layers and the sequence learning process is provided through the LSTM layers. In this work, we have used EEG signals obtained from left and right hemispheres of the brain. Our work has provided 99.12% and 97.66% classification accuracies for the right and left hemisphere EEG signals respectively. Hence, we can conclude that the developed CNN-LSTM model is accurate and fast in detecting the depression using EEG signals. It can be employed in psychiatry wards of the hospitals to detect the depression using EEG signals accurately and thus aid the psychiatrists.
AtıfScopus279OpenAlex291İncele - MakaleYalnız künye2018Anonymous Processors with Synchronous Shared Memory: Monte Carlo Algorithms
Chlebus, Bogdan S.; De Marco, Gianluca; Talo, Muhammed; Aspnes, J; Bessani, A; Felber, P; Leitao, J
AtıfOpenAlex2İncele - BildiriAçık Erişim2018Scopus SJRQ2Evaluating deep learning models for sentiment classification
Ay Karakuş, Betül; Talo, Muhammed; Hallaç, İbrahim Rıza; Aydin, Galip
Deep learning has emerged as an effective solution to various text mining problems such as document classification and clustering, document summarization, web mining, and sentiment analysis. In this paper, we describe our work on investigating several deep learning models for a binary sentiment classification problem. We used movie reviews in Turkish from the website www.beyazperde.com to train and test the deep learning models. We also report a detailed comparison of the models in terms of accuracy and time performances. Two major deep learning architectures used in this study are Convolutional Neural Networks and Long Short-Term Memory. We built several variants of these models by changing the number of layers, tuning the hyper-parameters, and combining models. Additionally, word embeddings were created by applying the word2vec algorithm with a skip-gram model on a large dataset (∼ 13 M words) composed of movie reviews. We investigate the effect of using the pre-word embeddings with these models. Experimental results have shown that the use of word embeddings with deep neural networks effectively yields performance improvements in terms of run time and accuracy.
AtıfScopus55WoS40OpenAlex64İncele - MakaleAçık Erişim2017Scopus SJRQ3Naming a Channel with Beeps
Chlebus, Bogdan S.; De Marco, Gianluca; Talo, Muhammed
AtıfOpenAlex16İncele