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- MakaleYalnız künye2022Scopus SJRQ3Ascorbic acid ameliorated the sperm quality of rainbow trout (Oncorhynchus mykiss) against arsenic toxicity: Impact on oxidative stress, fertility ability and embryo development
Kocabaş, Filiz Kutluyer; Kocabaş, Mehmet; Aksu, Önder; Çakir Sahilli, Yeliz
Arsenic (As) is a heavy metal and aquatic pollutant and adversely impacts the reproduction of male fish. As a chain-breaking antioxidant, ascorbic acid (AA) has high water solubility and low toxicity. In this context, the current study was performed to assess the protective role of AA (1 mM) on the sperm cells of the rainbow trout (Oncorhynchus mykiss) exposed to sublethal concentrations of As (8, 16 and 32 mg/L). Sperm quality parameters were analyzed using a sperm class analyzer system. Lipid peroxidation and antioxidant enzyme levels were used as indicators of oxidative stress. The fertilization, eyeing and hatching rates were determined as gamete markers. Reduced sperm quality parameters and fertility capacity resulted from in vitro exposure to As (P < 0.05). The oxidative stress in sperm cells increased after As exposure (P < 0.05). The presence of AA improved sperm movement parameters and fertility potential (P < 0.05). Overall, AA had a positive effect on oxidative stress and fertility ability against As toxicity and AA supplementation ameliorated detrimental effects of As in sperm cells.
AtıfScopus11WoS9OpenAlex5
İncele - MakaleAçık Erişim2020Scopus SJRQ1Investigation of potential health risks in terms of arsenic in grapevine exposed to gallery waters of an abandoned mining area in Turkey
Topal, Murat; Arslan Topal, E. Işıl; Öbek, Erdal
In this study, potential health risks in terms of arsenic in grapevine exposed to gallery waters of an abandoned mining area in Turkey were investigated. The concentrations of arsenic were determined in roots, stems, and leaves. The translocation factors and bioconcentration factors were calculated. The highest arsenic concentration in the grapevine was determined as 539.4±27 mg/kg, for root. The arsenic concentrations in grapevine as follows: Root>Leaf>Stem. The estimated daily exposure followed an order for the male, female, and children: dermal<inhalation<ingestion<dietary. The non-carcinogenic and total hazard index values calculated for As were higher than 1. The risk of arsenic to be carcinogenic has been determined. The highest carcinogenic risk can be listed as dietary > ingestion > inhalation > dermal. In our study, calculated carcinogenic risk values in terms of dietary, inhalation, and ingestion are higher than 10−4-10−6. As a result, the highest cancer risk on human health was determined as a dietary intake of grapevine leaves according to the calculated carcinogenic risk values.
AtıfScopus20WoS19OpenAlex21İncele - MakaleYalnız künye2015Scopus SJRQ3Determination and Health Risk Assessment of Heavy Metals in Drinking Water of Tunceli, Turkey
Demir, V.; Dere, T.; Ergin, S.; Cakir, Y.; Celik, F.
Tunceli, Turkey is one of the small cities in the Eastern Anatolian Region with substantial natural, cultural and historical heritage that is suitable to be a slow city. Water sources are abundant in the area due to rain and heavy snowfall in the mountains, which seeps into the ground or flows into the rivers. Therefore monitoring and conservation of city's drinking water quality is one of the main issues in the city. The present study was conducted to investigate several heavy metals and cyanide, arsenic, and selenium concentrations of drinking water samples taken from 100 different locations in the city and towns of Tunceli, Turkey during the years 2011 and 2012. In three locations, high levels of copper was found with a range of 2.1-11.5 mg/L, and high levels of arsenic was detected in five locations with a range of 10.5-78.0 mu g/L, exceeding the action levels for copper and arsenic. For health risk assessment, the average daily dose and hazard quotient (HQ) were calculated. The region mean values of HQ were found above 1 for arsenic in the samples collected from Mazgirt, while HQ values were below 1 in the rest of the samples.
AtıfWoS20OpenAlex33İncele