Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Topal, Murat(2)
- Torğut, Gülben(2)
- Aksakal, Bunyamin(1)
- Alak, Gonca(1)
- Arslan Topal, E. Işil(1)
- Arslan Topal, E. Işıl(1)
- Ateş, Burhan(1)
- Ayhan, Nagihan Karaaslan(1)
- Dik, Gamze(1)
- Gürel İnanlı, Ayşe(1)
- Gürler, N.(1)
- Gürler, Nedim(1)
- Karaaslan Ayhan, N.(1)
- Karaman, A.(1)
- Karaton Kuzgun, Nermin(1)
- Kuzgun, Nermin Karaton(1)
- Pekdemir, Mustafa Ersin(1)
- Say, Yakup(1)
- Selçuk Pekdemir, Sibel(1)
- Sinirlioglu, Zeynep A.(1)
- Tanyol, Mehtap(1)
- Taşgın, Yahya(1)
- Torgut, Gulben(1)
- Torǧut, G.(1)
- Ulu, Ahmet(1)
- Yazdıç, F.C.(1)
- Yazdıç, Ferit Can(1)
- Yılmaz, Demet(1)
- Çelik, Erdal(1)
- Öbek, Erdal(1)
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ2Pollution estimation and health risks assessment related to the agricultural application of mussel shell-derived chitosan as organic amendment
Arslan Topal, E. Işil; Topal, Murat; Çelik, Erdal; Öbek, Erdal
In this study, estimation of pollution and assessment of health risks related to the agricultural application of mussel shell–derived chitosan as organic amendment were evaluated. Furthermore, considering WHO maximum permissible levels in soil, the application rates of chitosan to agricultural soils were calculated. Geo-accumulation index (Igeo), enrichment factor (EF), contamination factor (CF), pollution load index (PLI), and ecological risk index (ERI) were calculated. Mussel shell-derived chitosan generally did not contribute to soil metal loading when evaluated in terms of those indices. The highest hazard quotient for ingestion (HQing) across male (ML), female (FML), and children (CL) followed the order Cr > Ni > Mn >Pb >Zn >Cu, while maximum HQing among metals was observed in the order CL > FML > ML. For inhalation exposure, highest HQinh for all metals was also found in the order CL > FML > ML, with individual metal contributions following Mn > Ni > Cr >Zn >Pb >Cu. Maximum HQder exhibited the trend ML > FML > CL, and the metal-specific order for HQder was Cr > Pb > Ni >Zn >Mn >Cu. Hazard Index (HI) and Total HI for ingestion, inhalation and dermal exposure were all less than 1. Cancer risk was less than 1 × 10−6. Consequently, there were no pollution and health risks associated with the use of musselshell‑derived chitosan in agriculture as organic amendment.
- MakaleYalnız künye2025Scopus SJRQ2Hydrocolloid materials of fish bone-derived in edible films: can hydroxyapatite be an alternative approach to improving fillet shelf life?
Alak, Gonca; Kuzgun, Nermin Karaton
The valorization of industrial fish waste has gained significant scientific interest due to its integrated benefits such as waste management and resource recovery. The aim of this study is to evaluate the effectiveness of fish bones, which is one of the wastes of aquaculture processing and constitutes approximately 9–15% of the waste generated as a result of the process, as a preservative in the food industry within the scope of green chemistry applications, sustainability and green product targets. In line with this objective, in the first stage, hydroxyapatite (HAP) was obtained from the fish bones, in the second stage, chitosan (Ch)-based coating solutions were enriched with HAP at different levels (0.02, 0.04 and 0.08 g / L) and in the last stage, fillets were coated with this solution and fillet quality parameters were monitored by microbiological, chemical and sensory analyses at certain intervals (0, 3, 6, 9 and 12 days) during 12 days of storage (at + 4 °C). Based on the data obtained during the storage period, the shelf life of control (Chitosan, Ch). chitosan + low HAP (Ch + L-HAP) and chitosan + medium HAP (Ch + M-HAP) fillet groups increased by 50%, 26% and 20%, respectively, compared to chitosan + high HAP (Ch + H-HAP). In the findings obtained, it was determined that the high concentration application (Ch + H-HAP) had a negative effect on all the parameters studied in fillets, and when the data on the last day of storage, especially the microbiological results were taken into consideration, it was determined that the shelf life decreased by 20–50% on average compared to the other concentrations (Ch + L-HAP and Ch + M-HAP) and Ch group and caused serious negativities in sensory parameters. Based on this result, it would be useful to try low and medium levels of this compound in different combinations. These findings indicate that HAP-enriched chitosan coatings have potential as a promising delivery system for the effective and controlled transport of bioactive ingredients in the food industry.
AtıfScopus5WoS5OpenAlex5
İncele - MakaleAçık Erişim2025Scopus SJRQ2PCL/chitosan composite films enhanced with Bi2O3 in nuclear shielding applications: Irradiation resistance, thermal and structural properties
Yılmaz, Demet; Pekdemir, Mustafa Ersin; Dik, Gamze; Selçuk Pekdemir, Sibel; Ulu, Ahmet; Taşgın, Yahya; Ateş, Burhan
In this work, irradiation resistance, thermal, and structural characteristics of Bi2O3-reinforced poly ε-caprolactone/chitosan composites for nuclear shielding applications were studied. PCL/CTS/Bi2O3 composite films were prepared by using different amounts of Bi2O3 (0.5%–4.0% (w/v)). The radiation shielding parameters of the synthesized composite films were both experimentally and theoretically measured at the high energy region. The equivalent dose rates of the prepared film samples were measured using a fast neutron source. Also, to determine the irradiation resistance, the samples were irradiated with Am-241 and Co-60 sources for 30 days. The MFP values at 80.99 keV changed by approximately 61% in samples PCL/CTS and PCL/CTS/4% Bi2O3. The results show that Bi2O3 content increases the gamma shielding abilities in PCL/CTS films. According to TGA results, the thermal stability of the polymer composite films is increased by the addition of Bi2O3 to the PCL/CTS blend film. The results show that PCL/CTS composite materials can be used as protective coating materials for nuclear shielding. Highlights: PCL/CTS/Bi2O3 composite films were prepared by the solvent casting method. The thermal stability of the composite films increased by increasing the Bi2O3 amount. Bi2O3 increased the LAC and MAC values of the composite films. PCL/CTS/Bi2O3 composite films have a neutron shielding effect.
AtıfScopus5WoS5İncele - MakaleYalnız künye2024Scopus SJRQ3Development of a novel rare earth element doped chitosan-graft-poly(hydroxyethyl methacrylate) composite for biomedical applications: synthesis, characterization, drug delivery, and antibacterial properties
Gürler, N.; Torǧut, G.; Yazdıç, F.C.; Karaman, A.; Karaaslan Ayhan, N.
The films of chitosan-graft-poly(hydroxyethyl methacrylate) polymer (Ch—g-poly(HEMA)) doped with the rare earth element (REE) lanthanum (La content of 0, 0.2, 0.4, and 0.8 wt.%) were fabricated. The films were characterized by attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy, scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS), thermogravimetric analysis (TGA), and powder X-ray diffraction (XRD) analysis. The films obtained were loaded with a model drug tetracycline by freezing/thawing method. The cumulative drug release properties of tetracycline were investigated. The release of tetracycline from the polymer matrix was carried out in phosphate-buffered saline (PBS) buffer (pH 7.4) at 37 °C. It was found that the REE-doped composite films had a retarding effect on tetracycline drug release compared to that of the undoped film. All tested composites regardless of the REE dopant content were found to be active against three Gram-positive and three Gram-negative bacterial strains used to assess the antimicrobial properties of the polymer composites. These findings demonstrated that lanthanum and tetracycline have a high affinity for the Ch—g-poly(HEMA) polymer and suggested a synergistic effect in the polymer—lanthanum—tetracycline system. The La3+-doped Ch—g-poly(HEMA) composite film can be used as drug carrier system in the biomedical field.
AtıfScopus4WoS4OpenAlex3İncele - MakaleAçık Erişim2024Scopus SJRQ3Structural, Dielectric, and Electrical Properties of Chitosan Composites Doped with Silver for Electrochemical Applications
Ayhan, Nagihan Karaaslan; Torgut, Gulben
In this study, chitosan-silver (Chs-Ag) composites containing Ag in different concentrations (0.01–0.08 M) were prepared. The characterization and structure studies of the composites containing 0.01, 0.02, 0.04, and 0.08 M Ag were carried out, and then the dielectric properties of these composites were examined. The composites were characterized by Fourier transform infrared spectrophotometer (FTIR), scanning electron microscopy and energy dispersive spectroscopy (SEM-EDS), and thermogravimetric analysis (TGA). The dielectric and electrical properties of these composites were investigated depending on the frequency at room temperature, and these properties were determined using an impedance analyzer. Spectroscopy revealed that the dielectric constant (ε′), dielectric loss (ε′′), and real (Z′) and imaginary (Z″) components of impedance are found to decrease with increased frequency for both Chs and Chs-Ag (0.01M–0.08 M) composites. On the contrary, the AC conductivity (σac) of samples increased with increasing frequency. ε′ and ε′′ values of Chs were lower than when the Ag was added. The AC conductivity was improved by the addition of silver particles. The results show that the dielectric and electrical properties of Chs-Ag samples were improved by using Ag as filler.
AtıfScopus3WoS3OpenAlex4İncele - MakaleAçık Erişim2022Scopus SJRQ1Chitosan-graft-poly(N‑tert‑butylacrylamide) Copolymer: Synthesis, Characterization and Optimization of Tetracycline Removal Using RSM
Tanyol, Mehtap; Torğut, Gülben
In the present study, a graft copolymer was synthesized in accordance with the free radical method using N-tertiary butylacrylamide monomer on chitosan, which is an environmentally friendly polymer. The chemical structure and surface morphology of the newly synthesized graft copolymer were determined by Fourier transform infrared spectroscopy, scanning electron microscopy and X-ray diffraction. Moreover, the thermal behavior was analyzed by thermogravimetric analysis. The chitosan-graft-poly(N‑tert‑butylacrylamide) graft copolymer was used as an adsorbent for the rapid removal of tetracycline from aqueous solutions in order to investigate its applicability. Response surface methodology (RSM) was employed for the optimization of the study conditions, namely adsorbent dosage (0.01–0.04 g 100 mL−1), reaction time (10–90 min) and initial tetracycline concentration (10–100 mg 100 mL−1). The effects of these conditions on tetracycline uptake capacity were examined and the results were statistically analyzed. The RSM results showed that the maximum tetracycline uptake capacity of 104.81 mg g−1 was achieved under the following conditions: adsorbent dose of 0.03 mg 100 mL−1, reaction time of 51.12 min and initial tetracycline concentration of 97.99 mg L−1. ANOVA based on central composite design combined with RSM showed a good agreement between the experimental values and quadratic model estimates, thus resulting in a coefficient (R2) of 0.9118 for tetracycline uptake. The kinetics, isotherms, and thermodynamics of adsorption were examined, and results showed that equilibrium data fitted the Freundlich isotherm model, and the adsorption kinetics of tetracycline followed pseudo-second-order model. Thermodynamic parameters like the enthalpy − 10.39 kJ mol−1 (ΔH°), entropy 0.044 kJ mol−1 K−1 (ΔS°) and Gibbs free energy − 23.26 kJ mol−1 (ΔG°) were evaluated and also, ΔG° shows a negative values indicating that the adsorption process was exothermic and spontaneous. The findings demonstrated that the chitosan-graft-poly(N‑tert‑butylacrylamide) copolymer is an effective adsorbent for pharmaceutical wastewater treatment.
AtıfScopus11WoS12OpenAlex11İncele - MakaleYalnız künye2022Scopus SJRQ2Silver/selenium/chitosan co-substituted bioceramic coatings of Ni–Ti alloy: Antibacterial efficiency and cell viability
Say, Yakup; Aksakal, Bunyamin; Sinirlioglu, Zeynep A.
The effects of silver (Ag), selenium (Se), and chitosan (Cht) additives on the antibacterial activity and cell viability of NiTi were investigated. Three different hydroxyapatite (HA)-based bioceramic coatings to improve the antibacterial activity and cell viability of NiTi; HA, HA/Ag, and HA/Se–Cht were applied to NiTi substrates by a sol–gel method. The coated samples were characterized by scanning electron microscopy–electron-dispersive spectroscopy and X-ray diffraction and surface hardnesses were measured. The antimicrobial efficiency of the coatings and uncoated surfaces were tested against Escherichia coli-JM 103 and Staphylococcus aureus-ATCC29293. In vitro cell–material interactions using Saos-2 osteoblast cells were characterized by a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mitochondrial activity test) assay for cell viability. A homogeneous, crack-free, and porous surface morphology is achieved in coatings. It has been shown that the Se–Cht additives did not have a significant effect on the surface hardness of the HA coating, but the Ag additive increased the hardness. Through in vitro antibacterial activity and cell viability tests, it was shown that Ag additive to bioceramic coatings significantly increased (p <.05) antibacterial properties but caused a decrease in cell viability. However, although Se–Cht additives did not have a significant effect on antibacterial properties (p <.05), it was observed that they increased cell viability.
AtıfScopus8WoS8OpenAlex2İncele - MakaleYalnız künye2022Scopus SJRQ2Synthesis, characterization, pH-sensitive swelling and antimicrobial activities of chitosan–graft-poly(hydroxyethyl methacrylate) hydrogel composites for biomedical applications
Torğut, Gülben; Yazdıç, Ferit Can; Gürler, Nedim
In this paper, 2-hydroxyethyl methacrylate (HEMA) was graft copolymerized onto chitosan (CHI) at different ratios using a radical initiator. The grafted hydrogel composites were then characterized by attenuated total reflection Fourier transform ınfrared spectroscopy (ATR-FTIR) and thermo-gravimetric analysis (TGA). Swelling behavior of the hydrogels was investigated at different pH and different times. The antimicrobial activity of the chitosan-graft-HEMA (CHI-HEMA) against gram-negative bacteria and gram-positive bacteria was studied by the standard agar well diffusion assay method. The CHI-HEMA 1:1 and CHI-HEMA 1:2 showed an obvious antimicrobial effect against six test strains. The CHI-HEMA 1:1 and CHI-HEMA 1:2 exhibited a highly significant increase (p < 0.01) in diameter of the inhibition zones compared with the standard antibiotics. Furthermore, CHI-HEMA 1:1 presented the highest antimicrobial activity against all test strains with a significant difference (p < 0.01) compared with CHI-HEMA 1:2. Meanwhile, the decreasing order of the average sensitivity to CHI-HEMA 1:1 and CHI-HEMA 1:2 was observed to be S. marcescens > E. coli > S. aureus subsp. aureus > S. enteritidis > E. faecalis > E. aerogenes. These results indicate potential application of CHI-HEMA 1:1 and CHI-HEMA 1:2 graft hydrogels as a novel and efficient antimicrobial agent in biomedical fields.
AtıfScopus40WoS36İncele - MakaleAçık Erişim2020Scopus SJRQ1Optimization of tetracycline removal with chitosan obtained from mussel shells using RSM
Topal, Murat; Arslan Topal, E. Işıl
In this study, the removal of tetracycline from aqueous solutions with chitosan obtained from mussel shells was optimized and investigated using responce surface methodology. For this aim, the central composite design was used to optimize the four variable factors (sorbent dosage (0.4–1.0 g), time (20−60 min), temparature (10−30 °C) and initial TC concentration (50−100 mg/L)) for the removal of TC from aqueous solutions by chitosan obtained from mussel shells. According to the RSM analysis results, optimum conditions for maximum TC removal efficiency were determined as 90.5 mg/L for initial TC concentration, 35.9 min for time, 29.9 °C for temperature and 0.4 g for sorbent dosage. It was observed that the tetracycline was crystallized on mussel shells. According to the results of XRD after adsorption, the content of mussel shells were observed as 60% calcite, 5.6% overite, 9.4% aragonite and calcium hydroxide 25%, respectively. As a result, experiments showed that chitosan obtained from mussel shells were a good adsorbant for tetracycline removal from aqueous solutions.
AtıfScopus53WoS52OpenAlex53İncele - MakaleAçık Erişim2018Scopus SJRQ1The investigation of the shelf life at 2 ± 1 °C of Luciobarbus esocinus fillets packaged with films prepared with the addition of different essential oils and chitosan
Karaton Kuzgun, Nermin; Gürel İnanlı, Ayşe
In this study, the chemical, microbiological and sensory changes during storage at 2 ± 1 °C of Luciobarbus esocinus fillets coated with edible films prepared with chitosan incorporation of thyme, clove, rosemary essential oils were examined. To create the experimental samples, a total of six groups of L. esocinus fillets coated with different edible films (normal, vacuum-packed, chitosan, chitosan with added thyme oil, chitosan with added clove oil, and chitosan with added rosemary) were used. The food composition of the fillets and experimental samples were determined after they had been coated with edible films. The results of analysis showed that, the preservation period of fresh fillets ended on day 12th, that of vacuum-packed fillets on day 15th, that of fillets coated with chitosan incorporation of rosemary on day 27th, that of fillets coated with chitosan incorporation of thyme and chitosan incorporation of cloves on day 30th. In comparison with the control group, fish spoilage was significantly delayed in samples coated with chitosan incorporation of thyme and chitosan incorporation of cloves (p < 0.05). The lowest bacterial growth, values of PV, TBA and TVB-N were obtained in fish samples coated with thyme + chitosan and cloves + chitosan. In terms of the general acceptability of the fish, as determined by qualified panelists, it was determined that the highest score was given to the experimental group to which essential oil of clove had been applied.
AtıfScopus16WoS12OpenAlex17
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