Yayınlar
Koleksiyondaki öğeler
- MakaleYalnız künye2023Scopus SJRQ2Anti-tank impact absorption with a reinforced concrete plate design
Polat, Berivan Yilmazer; Savaş, Sedat; Polat, Alper
Anti-tank weapons are among the infantry weapons used by the armies of many countries. Anti-tank rockets and explosives such as TNT, generally used for armour piercing, are also frequently used in terrorist attacks. These attacks damage the protection facilities built from reinforced concrete. Rockets or similar explosives’ rapid speed and burst temperatures pierce reinforced concrete during strikes, resulting in casualties and damage to crucial strategic structures. This study aimed to devise an economic and applicable reinforced concrete plate that could absorb the impact of anti-tank rockets and Trinitrotoluene (TNT) type explosives. Therefore, 5 different samples, produced from C50 reinforced concrete and 150×150 cm in size, were formed by combining plates of different numbers and thicknesses. Also, a sample, which was a single thick plate, was prepared. In destructive testing, Rocket Propelled Grenade (RPG-7) was used as the anti-tank rocket launcher. As a result of this study, the impact damage was reduced with hollow concrete plate geometries, and recommendations were developed for complete prevention.
AtıfScopus2WoS3
İncele - MakaleYalnız künye2023Scopus SJRQ2The effect of occupational training provided to workers in a glass factory on their use of ear protectors
Yeşiltepe, Akgün; Karadağ, Gülendam
Objectives. This study aimed to determine the effect of occupational training applied to workers working in noisy parts of a glass factory on the use of ear protectors. Methods. The study was a semi-experimental pre-test and post-test design. It was carried out with 45 workers determined by purposeful sampling and working in a glass production factory who accepted to participate in the study. The data were collected with an information form and noise-related symptom chart, hearing health information questionnaire and observation. In the analysis of the study data, the number/percentage, χ 2 test, Cohen κ test and analysis of variance were used. Results. It was determined that workers pre training did not use ear protectors (100%) and there were some noise-related health complaints. There was an increase in using ear protectors (57.8%) and a decrease in their health complaints post training. It was also found that the workers’ pre-training hearing health information questionnaire mean score was 11.46 ± 3.20, and post training was 13.77 ± 3.42 in the first month and 15.77 ± 2.88 in the fourth month. Conclusions. Occupational training provided to the workers increased the workers’ awareness level and their rate of wearing ear protectors, and health problems caused by work-related noise started to recover.
AtıfScopus1WoS1OpenAlex2
İncele - MakaleAçık Erişim2022Scopus SJRQ3Electrochemical Detection of Ivermectin Used for the Treatment of COVID-19 with Glutardialdehyde-Modified Glassy Carbon Electrode
Koçak, Berna; İpek, Yeliz
In this study, the surface of the glassy carbon electrode was modified with glutardialdehyde. The modified glassy carbon electrode showed electrocatalytic activity against ivermectin. The glassy carbon electrode modified with glutardialdehyde showed high sensitivity, selectivity, and stability in the determination of ivermectin. The peak current of glutardialdehyde oxidation obtained by differential pulse voltammetry decreased inversely with the ivermectin concentration. Ivermectin inhibited the oxidation reaction of glutardialdehyde and caused a decrease in current. This change made the analysis of ivermectin electrochemically possible. In order to demonstrate the applicability of the developed method in real samples, recovery studies were carried out in tap water and urine. The highest sensitivity (0.45 µA/((µmol·L−1)(cm2))) was achieved with urine sample and the lowest detection limit as 2.66 × 10−6 mol·L−1 was obtained with BRT solution sample. Graphical abstract: [Figure not available: see fulltext.]
AtıfScopus14WoS13OpenAlex13İncele - MakaleYalnız künye2023Scopus SJRQ4Bibliometric mapping of research trends in education, physical education, and sports for the disabled
Karakaya, Yunus E.; Dikmen, Melih; Şahin, Aykut
In this study, a relational systematic map of research trends in education, physical education, and sports for disabled people was prepared with the bibliometric mapping method. Scientific data obtained from the Web of Science (WoS) was used in the research. After the search in the WoS database, 423 studies were accessed, and 415 of these were included in the final analysis by applying the exclusion criteria. The VOSviewer (Visualization of Similarities) program was used for the bibliometric analysis. The results of the research demonstrate that the number of studies in the field has increased from the 1980s to the present day. The studies included in the research were published in 50 different countries, in 133 different journals and were carried out by 770 authors working in 409 different universities/institutions. According to the findings, most of the research, the highest number of citations, and the most influential authors were based in the United States of America. The results showed that the most cited author in this field works collaboratively with many national and international researchers. The results of the research may provide practical information for politicians, practitioners, and lecturers to draw their attention to new research trends and opportunities regarding education, physical education and sports for individuals with disabilities.
AtıfScopus1WoS1İncele - MakaleYalnız künye2022Scopus SJRQ2Comparative Content, Biological and Anticancer Activities of Heracleum humile Extracts Obtained by Ultrasound-Assisted Extraction Method
Ocal, Mustafa; Altunoglu, Yasemin Celik; Angeloni, Simone; Mustafa, Ahmed M.; Caprioli, Giovanni; Zengin, Gokhan; Paksoy, Mehmet Yavuz; Baloglu, Mehmet Cengiz
As the safety and effectiveness of synthetic drugs remain in doubt, researchers are trying to develop natural medicines from medicinal plants. Herein, ethyl acetate, methanol and water extracts from the Heracleum humile plant were obtained by an ultrasonic-assisted extraction process and the aim was to evaluate some biological effects of the extracts due to the limited data on the pharmacological properties of Heracleum humile in the literature. Weak antibacterial activity was observed on tested bacterial species. The minimum inhibitory concentration and the minimum bactericidal concentration values ranged from 250 to 500 μg/mL. In addition, cytotoxic activity was determined using the MTT test. The strongest findings were determined for ethyl acetate extract on the MDA-MB-231 cell lines at the 48th hour (IC50:97.94 μg/mL), followed by the MCF-7 cell lines at the 24th hour (IC50:103.9 μg/mL). All extracts of Heracleum humile contained mainly flavonoids, phenolic acids and their derivatives, i. e., well-known compounds that possess numerous biological activities such as antioxidant, anti-inflammatory, anticancer, antimicrobial etc. The study results could provide important information that Heracleum humile could be a potential candidate as a natural enzyme inhibitor. It can be concluded that these extracts could be useful in the elementary step of improving novel plant-derived multifunctional pharmaceuticals.
AtıfScopus6OpenAlex11İncele - MakaleAçık Erişim2021Scopus SJRQ4Presence of Neospora caninum DNA of Wild Birds from Turkey; [Türkiye’deki Vahşi Kuşlarda Neospora caninum DNA’sının Varlığı]
Karakavuk, Muhammet; Can, Hüseyin; Aldemir, Duygu; Döndüren, Ömer; Karakavuk, Tuğba; Karakavuk, Emrah; Özdemir, Hüseyin Gökhan; Muz, Mustafa Necati; Gürüz, Adnan Yüksel; Döşkaya, Mert
Objective: Neospora caninum is a protozoon parasite that has a worldwide distribution and mainly causes abortion in cattle and current serological evidence shows that the disease may be also zoonotic. Wild birds play a role as a reservoir of the disease in nature. The study aimed to determine the prensence of N. caninum in wild birds. Methods: In this study, the presence of neosporosis in wild birds (n=55) including 22 different species found in the western side of Turkey, was investigated by polymerase chain reaction (PCR). In addition, PCR positive samples were confirmed by sequencing, BLAST, and phylogenetic analysis using MEGA7. Results: Obtained results showed that the presence of N. caninum DNA was 5.45% (3/55) in brain-heart homogenates wild birds. The bird species which were found positive for N. caninum were little owl (Athene noctua), common buzzard (Buteo buteo), and little tern (Sternula albifrons). According to phylogenetic analysis and BLAST, all samples were compatible with reference N. caninum isolates. Conclusion: To the best of authors’ knowledge, this is the first study detecting N. caninum in little tern. In future studies, it may be interesting to investigate the prevalence of N. caninum in other wild animals to elucidate the transmission properties.
AtıfScopus3OpenAlex3
İncele - Kitap BölümüYalnız künye2021Fine–kinney-based occupational risk assessment using fuzzy best and worst method (f-bwm) and fuzzy mairca
Gul, Muhammet; Mete, Suleyman; Serin, Faruk; Celik, Erkan
The best-worst method (BWM) proposed by Rezaei (Omega 53:49–57, [1]) is an MCDM method used to achieve the weights of the criteria by making fewer pairwise comparisons and using more consistent decision matrices. In this chapter, instead of crisp numbers, triangular fuzzy numbers that reflect the uncertainty well in real-world problems are used in integration with the BWM method (Guo and Zhao in Knowl Based Syst 121:23–31, [2]) in determining factor weights. Using the fuzzy best and worst method (F-BWM), a model based on Fine–Kinney occupational health and safety risk assessment method was developed for the first time in the literature. Three parameters of Fine–Kinney method are weighted by the mathematical models of F-BWM. Then, the risks are prioritized by fuzzy multi-attribute ideal real comparative analysis (F-MAIRCA). A case study was conducted to demonstrate the feasibility of the approach, and besides this case study, a comparative study was also conducted to test the validity of the proposed approach. This approach led to the conclusion that Fine–Kinney’s method, BWM, MAIRCA, and triangular fuzzy sets make the risk decision-making process more dynamic, taking into account the benefits of these methods individually or in integration.
AtıfScopus11OpenAlex12İncele - MakaleAçık Erişim2021Scopus SJRQ3Preliminary investigation on chemical composition and bioactivity of differently obtained extracts from Symphytum aintabicum Hub.- Mor. &Wickens
Zengin, Gokhan; Sinan, Kouadio Ibrahim; Ak, Gunes; Angeloni, Simone; Maggi, Filippo; Caprioli, Giovanni; Kaplan, Alevcan; Çakılcıoğlu, Uğur; Akan, Hasan; Jugreet, Sharmeen
Symphytum species, commonly known as comfrey, hold a long history of folk medicinal uses for healing wounds, bone fractures and other pain resulting from inflammation. However, many species belonging to this genus have not yet been scientifically investigated and hence investigation in this regard is warranted. In the present research, S. aintabicum extracts prepared by different extraction techniques (homogenizer assisted extraction, infusion and maceration) were assayed for their chemosystematic attributes (total phenolic, flavonoid) as well as bioactive compound contents, antioxidant and enzyme inhibition potentials. For instance, the extracts were found to possess phenolic and flavonoid levels ranging from 35.50 to 112.25 mg GAE/g and 2.54–25.12 mg RE/g, respectively. In general, the extracts displayed significant antioxidant activity. However, methanolic and infusion extracts were observed as the most potent radical scavengers and reducing agents, most likely related to their phenolic content. The extracts also showed metal chelating power and total antioxidant capacity in phosphomolybdenum assay. Moreover, while all extracts showed inhibition on amylase, only the methanolic extracts acted as inhibitors of cholinesterases and tyrosinase, most probably due to their relatively higher flavonoid content. The findings also indicated that the extraction method as well as the solvent type used to more or less affect the yield of the bioactive compounds and extracts’ bioactivity reported herein. Hence, as a first report highlighting the in vitro pharmacological properties of S. aintabicum, promising results were revealed from the quantitative chemosystematic analysis of bioactive components present and as sources of antioxidants and enzyme inhibitors against key human illnesses, thus providing scope for potential applications in phytomedicine development.
AtıfScopus15OpenAlex14İncele - MakaleYalnız künye2021Scopus SJRQ2Synthesis and in silico studies of Novel Ru(II) complexes of Schiff base derivatives of 3-[(4-amino-5-thioxo-1,2,4-triazole-3-yl)methyl]-2(3H)-benzoxazolone compounds as potent Glutathione S-transferase and Cholinesterases Inhibitor
Adiguzel, Ragip; Türkan, Fikret; Yildiko, Ümit; Aras, Abdülmelik; Evren, Enes; Onkol, Tijen
Novel Ru(II) complexes of Shiff base derivatives of 3-[(4-amino-5-thioxo-1,2,4-triazole-3-yl)methyl]-2(3H)-benzoxazolone were synthesized. The ligands (1a-e) were confirmed by IR, 1H NMR, and 13C NMR spectra (only 1b and 1c). Structures of the synthesized Ru(II) complexes (2a-e) were illuminated by elemental analysis, IR, 1H NMR, 13C NMR, and mass spectra. As the biological studies, the inhibitory potency of the ligands and the novel synthesized complexes were evaluated against the glutathione S-transferase (GST), acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes in vitro conditions. Ki values in the range of 26.87-47.63 µM for AChE, 23.51-42.81 µM for BChE, and 33.14-51.73 µM for GST, respectively. The free binding energy of most active inhibitors against AChE, BChE, and GST enzymes were detected as -10.183 kcal/mol, -9.111 kcal/mol, and -6.097 kcal/mol, respectively. All compounds docked were observed to bind in the active site of the enzymes with similar binding orientation and binding interactions with the surrounding amino acids.
AtıfScopus31OpenAlex34İncele - MakaleYalnız künye2021Scopus SJRQ2Characterization of Various Carbon-Based Polypropylene Nanocomposites
Kaya, Ozge; Buran, Dincer; Akkurt, Nevzat; Yapici, Kerim; Sarac, Mehmet Fahri
Pure and three types of carbon additives including graphite, graphene, and multi-walled carbon nanotube added into polypropylene (PP) composites as a vibration damping component and sound insulator material in the automotive sector were investigated by using vibrational damping, dynamic mechanical analysis (DMA), tensile, hardness and acoustic behavior tests. According to the obtained results, porosity and distribution of carbon in the polymer matrix are key parameters on the composite parameters causing its reduction of tensile strength and its brittle behavior. Moreover, it seems that 0.01 wt.% graphene and 1 wt.% graphite added PP composites show the highest impact damping properties and also increase the storage and loss modulus of the composite while decreasing the glass transition temperature. The loss factor obtained from DMA and vibration damping test indicated the damping capacity in the interphase of carbon added PP composites depends only on the load applied and not sensitivity upon the natural frequency of the composite system. Depending on the morphological differentiation, graphene added PP composites decrease the sound transmission loss while the 0.1 wt.% MWCNT added PP composites increase sound transmission loss which makes it an alternative vibration damping component.
AtıfScopus6WoS6İncele - MakaleYalnız künye2021Scopus SJRQ2Investigation of Tie Bars Axial Force Demands in Composite Plate Shear Walls—Concrete Filled
Polat, Erkan; Kenarangi, Hadi; Bruneau, Michel
Tie bars axial force demands due to concrete dilation and prying action were investigated through numerical studies. In the first part of this study, the Karagozian and Case Concrete model, which proved to provide reasonable in-plane flexural cyclic inelastic wall response while accounting for concrete dilation effect, was used to investigate the variation of confinement inside the infill concrete, the distribution of passive confining pressures at the steel–concrete interface, and the resulting tie bar axial force demands. Finite element analyses involving C-PSW/CF having different tie spacings, wall depths, and wall thicknesses were performed. In the second part of this study, the influence of plate local buckling on tie bar axial force demand was investigated and explained by prying action. A separate finite element study was performed to investigate the significance of prying action and equations were developed from free-body diagrams. The results showed the significance of the passive confining pressures due to concrete dilation, and prying action due to local plate buckling, on imparting axial forces in tie bars. Neither of these behavior are currently considered as design parameters for tie bars. The numerical analyses and results presented here are intended to provide useful insights and direction for the design and instrumentation of future C-PSW/CF experiments by the broader research community.
AtıfScopus9WoS8OpenAlex8İncele - MakaleAçık Erişim2022Scopus SJRQ3Antioxidant, Antityrosinase Activities and Composition of Essential Oils Obtained from Roots and Fruits of Ferulago longistylis Boiss.
Kürkçüoğlu, Mine; Ağalar, Hale Gamze; Temiz, Burak; Duran, Ahmet; Paksoy, Mehmet Yavuz; Başer, Kemal Hüsnü Can
This study was aimed to evaluate the potential uses of Ferulago longistylis Boiss. essential oils in cosmetic applications. The air dried roots and fruits were subjected to water distillation by using a Clevenger apparatus for 3 h. Both essential oils were analyzed by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC/MS) systems, simultaneously. The essential oil yields of the fruits and roots were calculated as 4% and 0.91%, respectively. The major compounds were identified as 2,3,6-trimethylbenzaldehyde (29.5%), cis-chrysanthenyl acetate (15.2%), (Z)-β-ocimene (12.4%), α-pinene (12.0%) and myrcene (11.4%) in the fruit essential oil while the root essential oil was characterized with high content of α-pinene (90.5%). Both essential oils were evaluated for their potential antioxidant and antityrosinase activities. The both essential oils showed weak Trolox equivalent antioxidant capacity and DPPH radical scavenging activity. The fruit essential oil showed weak antityrosinase (%25 inhibition, 1 mg/mL) activity while the root essential oil was inactive. The results concluded that both essential oils were not promising in cosmetic applications.
AtıfScopus3OpenAlex1TR Dizin1İncele - MakaleAçık Erişim2022Scopus SJRQ2The Bioremediation Capacity of Sphingomonas melonis for Methomyl-Contaminated Soil Media: RSM Optimization and Biochemical Assessment by Dreissena polymorpha
Önder Erguven, Gokhan; Serdar, Osman; Tanyol, Mehtap; Cikcikoglu Yildirim, Nuran; Yildirim, Numan; Durmus, Barbaros
The bioremediation capacity of S. melonis for methomyl investigated with RSM. Oxidative stress and neurotoxic response determined in D. polymorpha. COD and TOC levels were measured. GSH, MDA levels and CAT, SOD, AChE activities in D. polymorpha exposed to before (group A) and after (group B) bioremediated media during 24 and 96 h were tested by using ELISA kit. AchE activity was decreased 24th h but increased during 96th h in group B compared with group A (p<0.05). MDA levels and CAT activities were decreased during 24 h and 96 h in group B compared with group A (p<0.05). GSH levels were increased during 24 h and 96 h in group B compared with group A (p<0.05). SOD activity did not show a significant change in group B (p<0.05). Methomyl could be effectively remediated by S. melonis and CAT, AChE activities and GSH, TBARS levels of D. polymorpha are useful biomarkers for evaluating the bioremediation capacity.
AtıfScopus5WoS6OpenAlex6İncele - Kitap BölümüYalnız künye2021Economic and social impacts of COVID-19 on European tourism
Kazar, Gorkemli; Kazar, Altug; Akpinar, Tuba
European tourism has been largely disrupted by the pandemic throughout 2020. In this study, the economic and social effects of COVID-19 on the tourism sector of European countries were examined. To understand the extent of the pandemic on European tourism, policies followed by countries, physical tourism flows of the accommodation sector, tourism employment, and turnover rates were considered. The study showed that the European tourism sector, especially after the second half of 2020, was hit socially and economically by the devastating effects of the pandemic. In addition, the study revealed the necessity for radical regulations within the sector in the post-pandemic period.
- MakaleYalnız künye2022Scopus SJRQ3Boron-incorporated biocomposite coatings on 316L and NiTi alloys: Enhanced structural, antibacterial activity, and cell viability performances
Aslan, N.; Aksakal, B.; Aksoy, M.E.
Boron doped (5 %, 10%, and 15 wt.%) Hydroxyapatite (B-HA) biocomposites were syntesized and coated on 316L SS and NiTi (Ni-45Ti) metallic substrates by using the electrophoretic deposition process (EPD). The morphological and structural characterization of the coatings was executed using scanning electron microscopy (SEM) and X-ray diffraction devices (XRD). Antibacterial tests were conducted using Escherichia coli (E. coli, JM103) and Staphylococcus aureus (S. aureus, ATCC29293) microorganisms. The mitochondrial activity assay (MTT)-[3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] was used to examine cell viability and cytotoxicity in Saos-2 osteoblast cells. HA and boron peaks, as well as B-TCP and metallic components, were detected in XRD examinations. Porous morphologies were generated on the surface with boron doped B-HA coatings, as revealed by SEM views. Antibacterial activity studies revealed that both metallic coating groups, notably with boron doping, demonstrated antibacterial activity against gram-negative E. coli and gram-positive S. aureus. The antibacterial activity of the 316L group was shown to be better than that of the NiTi group in comparisonal testing. The syntesized boron-doped biocomposite coatings did not have any detrimental effects on living cells, according to cell viability studies. The cell viability rate was found to be greater in NiTi coatings than in 316 SS coatings, and the impact was amplified by the addition of boron.
AtıfScopus6WoS4OpenAlex7İncele - MakaleYalnız künye2023Scopus SJRQ1Improving dielectric properties, electrical conductivity, and thermal properties of biodegradable polymer composites prepared with lanthanum
Torgut, Gulben; Ayhan, Nagihan Karaaslan; Acikses, Aslisah
The precipitation method was adapted to synthesize the poly(ε-caprolactone-copolymer- ethylene oxide) (ε-CL-co-EO) composite with the salt of lanthanum (La), a rare earth element. This salt was incorporated into the polymer of different weight percentages to study how it affects the thermal and dielectric properties of the polymer. The resulting products were characterized by Fourier Transform Infrared Spectroscopy, X-ray diffractometry (XRD), Scanning electron microscopy (SEM) and thermogravimetric analysis. XRD and SEM data show that the polymer mixes homogeneously with the metal salt. Thermal degradation data show that the thermal stability of composites synthesized with La is lower than that of pure polymer. The dielectric properties and A.C conductivity measurements of the composites were investigated by using impedance analyzer in the frequency range (100 Hz to 20 kHz) at room temperature. The electrical property results of (ε-CL-co-EO)/La composites displayed that dielectric constant (έ), dielectric loss (ε"), tan delta (tan δ) and A.C electrical conductivity (σac) increase with increasing La content. The largest conductivity of (ε-CL-co-EO)/La composite filled with 20 wt% La was 8.80 × 10−8 S/cm, which was 162% times pure (ε-CL-co-EO). In addition, impedance (IZI) of composites was evaluated from the dielectric data. This procedure is eco-friendly and easy to handle, which provides a promising route to polymer composites in the application of the conductivity field.
AtıfScopus6WoS6OpenAlex7İncele - MakaleAçık Erişim2022Scopus SJRQ1Medical waste management during coronavirus disease 2019 pandemic at the city level
Polat, E.G.
Coronavirus disease 2019 brings about the economic damage and loss of life. Thus, demand of personal protective equipment continues to increase, consequently an increase in infectious equipment pollution. Most of these wastes threaten the environment and increase the spread of diseases. This paper provides a research hypothesis whether effective medical waste management would prevent the possible impacts of coronavirus disease 2019-related waste issues on environment at the city level. To confirm this hypothesis, installation of waste treatment centre is addressed. Then, by incorporating uncertain waste generation amounts utilizing Jimenez method, a pickup routing is addressed to decide the pickup routes between the waste treatment centre and residential area. This study is first to assign the optimistic, realistic and pessimistic scenarios of the uncertain waste generation using time series analysis method and waste generation formulation. Also, L-type matrix is used to define, assess and prioritize the environmental and operational risks on waste generation formulation and to provide risk reaction strategies. Practicality of these approaches is illustrated in the case of Turkey. The computational results reveal the effectiveness of the integrated method, which ensures practical and theoretical insights controlling the waste generation to prevent virus propagation for health authorities.
AtıfScopus15WoS13OpenAlex19İncele - Kitap BölümüYalnız künye2023A GIS-Based BWM Approach for the Location Selection of Solar Power Plant in Tunceli Province (Turkey)
Konurhan, Zekeriya; Yucesan, Melih; Gul, Muhammet
The world has recently tended to turn to renewable energy sources due to the serious negative impact of fossil fuels on the environment. One of the top priorities for solar energy is the selection of the most suitable location of the solar power plant to be established. In this study, the most suitable solar power plant location selection for Tunceli, a province located in the eastern part of Turkey, is studied with an approach based on Geographic Information System (GIS) and the best-worst method (BWM). A weighting was performed using the BWM model for 16 sub-criteria under four the main criteria of “climatic conditions, geographical conditions, land conditions, and location (distance to crucial points)”. Afterward, maps were created for these criteria, and a 6-point scale in the legends of each map for each sub-criteria was applied. Finally, the most suitable locations were determined with GIS-based calculations.
AtıfScopus6WoS5OpenAlex7İncele - MakaleYayıncıda açık erişim2021Scopus SJRQ2Investigation of antioxidant properties of chamomile consumed as herbal tea
Karaaslan Ayhan, Nagihan
Common chamomile is consumed as herbal tea due to its antioxidant properties and biological activities in daily life. In this study, antioxidant activities and total phenolic contents of white and yellow chamomiles were investigated in terms of extraction methods and solvent types. In all extraction methods used for extraction of both chamomiles, the best antioxidant activity and total phenolic results were obtained with water extracts. Also, the best yield was found with sonication-assisted stirring for both chamomile extracts obtained using three extraction solvents. DPPH and ABTS radical scavenging activities obtained by sonication-assisted stirring for water extracts were 10.886 ± 0.244 mg TEAC/g and 8.702 ± 0.567 mg TEAC/g for white chamomile, and 11.709 ± 0.693 mg TEAC/g and 11.139 ± 0.514 mg TEAC/g for yellow chamomile. The total phenolic contents were determined as 3.863 ± 0.325 mg GAE/g for white chamomile and 5.225 ± 0.417 mg GAE/g for yellow chamomile. Novelty impact statement: In this study, the antioxidant properties of white and yellow chamomile were examined in detail in terms of different extraction methods and solvent types. Sonication-assisted stirring and water were determined to be the best extraction method and solvent for both chamomiles. According to the results, it can be stated that chamomile has higher antioxidant properties than white chamomile under the best extraction conditions.
AtıfScopus9WoS9OpenAlex8İncele - MakaleYalnız künye2023Scopus SJRQ3Nafion–Titanium (IV) Oxide-Graphene Modified Glassy Carbon Electrode (GCE) Based Electrochemical Sensor for the Voltammetric Determination of the β-blocker Bisoprolol Fumarate
Koçak, Berna; İpek, Yeliz
A Nafion–titanium (IV) oxide-graphene modified glassy carbon electrode (n-TiO2-GR/GCE) was used for the electrochemical determination of bisoprolol fumarate (BF). The modified electrode was prepared by depositing Nafion–titanium (IV) oxide-graphene onto the glassy carbon electrode by simple drop-casting. Differential pulse voltammetry (DPV) and square wave voltammetry (SWV) were used in the electrochemical determination of bisoprolol fumarate. The linear working range of bisoprolol fumarate for n-TiO2-GR/GCE DPV was from 3.0 × 10−7 to 5.0 × 10−6mol L−1 and the detection limit was 1.01 × 10−7mol L−1. In addition, with this developed method, the determination of bisoprolol fumarate in tablets was successfully performed with a recovery of 98.65%.
AtıfScopus3WoS2OpenAlex3İncele
