Sürdürülebilir Kalkınma Amaçları

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Yazarlar

• Arslan, A.(1)
• Arslan, Ali(1)
• Danabas, D.(1)
• Danabas, Durali(1)
• Gulec, A. Kucukgul(1)
• Gulec, Azime Kucukgul(1)
• Kucukgul, A.(1)
• Kucukgul, Altuğ(1)
• Kucukgul, Azime(1)
• Seker, E.(1)
• Seker, Engin(1)
• Serdar, O.(1)
• Serdar, Osman(1)
• Ural, M.(1)
• Ural, Mesut(1)

• MakaleYalnız künye2017Scopus SJRQ4/r/munzur/3869
  Apoptotic effects of artificial feed supplemented with Thymus vulgaris on Oncorhynchus mykiss against Yersinia ruckeri

  Kucukgul, Altuğ; Kucukgul, Azime

  Chemical composition of the essential oil was analyzed by GC-MS, and found to contain the phenol (40.95 %) as major component. Results showed that Y. ruckeri (3 × 107cfu fish-1) infection caused the characteristic symptoms on rainbow trout (petechial hemorrhages on the surface of body and liver). Y. ruckeriinducedinhibitions of Cas-3, Cas-8, p53 and HSP-70. After the administration of thyme essential oil (10 mg kg-1 diet) to infected fish tissues, Cas-3, Cas-8, p53 and HSP-70 mRNAs were up-regulated by 9.31, 9.18, 9.58, and 6,1 fold change, respectively. According to the results of the study, the inhibitions seen all analyzed genes were due to Y. ruckeri infection. However, they were entirely increased by thyme treatment. Thus, targeting pro-apoptotic proteases by agents such as T. vulgaris could improve therapeutic options for infectious disease in fish.

  İncele
• MakaleYalnız künye2013Scopus SJRQ2/r/munzur/4672
  THERAPEUTIC EFFECTS OF THYME (THYMUS VULGARIS LINNEAUS) AND FENNEL (FOENICULUM VULGARE MILLER) ESSENTIAL OILS IN INFECTED RAINBOW TROUT, ONCORHYNCHUS MYKISS (WALBAUM)

  Gulec, A. Kucukgul; Kucukgul, A.; Danabas, D.; Ural, M.; Seker, E.; Arslan, A.; Serdar, O.

  The fish (84 +/- 1.02 g mean +/- SEM) were divided into 3 groups (N=15 in each group) as control (CNT), infected with Yersinia ruckeri (INF), and infected and essential oils (+EO). The CNT and INF groups were fed only with commercial fish feed. The +EO group was fed with feeds prepared with the rate of 10 ml herbal essential oils (mixed thyme and fennel) / 100 g feed during 21 days. The liver tissue (0.4 g) of fish was dissected in third day of the experimental period and mRNA transcription levels in liver tissue were determined by Real Time PCR analysis. INF and +EO groups exhibited decreased immunity against the challenging with Y. ruckeri infection (53.57 and 42.85 % mortality, respectively) when compared with CNT group (93.33 %). Gene mRNA transcription levels of tumour necrosis factor alpha (TNF-alpha), interleukin 1 beta (IL-1 beta), inducible nitric oxide synthesis (iNOS), serum amyloid A (SAA), that are responsible during the initiation and continuation of the inflammation increased in 1.86, 2.46, 1.62 and 55.7 fold change, respectively in INF group, whereas mRNA expressions of haptoglobin (Hp) decreased (1.2-fold change) in 3th day of experimental period. The +EO group eliminated the increase in all of the gene expressions.

  AtıfWoS7

  İncele
• MakaleAçık Erişim2013Scopus SJRQ2/r/munzur/4551
  Effect of mixed use of thyme and fennel oils on biochemical properties and electrolytes in rainbow trout as a response to Yersinia ruckeri infection

  Gulec, Azime Kucukgul; Danabas, Durali; Ural, Mesut; Seker, Engin; Arslan, Ali; Serdar, Osman

  The aim of study was to compare the effects of supplementation of food with herbal oils (Thymus vulgaris and Foeniculum vulgare) on biochemical properties and electrolytes of rainbow trout infected with Yersinia ruckeri. In total, 120 healthy fish (mean weight 84 +/- 1.02 g) were equally divided into four experimental groups. The experimental study was carried out for one week. The first group was control without supplementation and infection, the second group was infected and without oil supplementation, the third group was supplemented with oils (10 ml.100 g(-1) rates) for one week and infected with Y ruckeri and the last group was oil supplemented without infection. Results indicated that fish fed with dietary supplements showed enhanced bactericidal activity, total protein, albumin, cholesterol, triglyceride and bilirubin compared to the control (P < 0.05). As the value of herbal oils was increased in diets, the plasma glucose level decreased. The levels of K, Na, Ca, and Mg increased whereas Cl values decreased, compared to the control. It can be concluded that diet supplementation with herb oils used in this study can increase disease resistance by increasing levels of some biochemical parameters and electrolytes in rainbow trout to Y ruckeri infection.

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  AtıfWoS41·OpenAlex52

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