Sürdürülebilir Kalkınma Amaçları

• 3

Yazarlar

• Ali, L.A.(1)
• Aslan, N.(1)
• Aydoğdu, Hacı Mehmet(1)
• Açar, Gülistan(1)
• Cihangir, Salih(1)
• Dikici, B.(1)
• Erden, Yavuz(1)
• Erecevit Sönmez, Pınar(1)
• Gürler, N.(1)
• Karaaslan Ayhan, N.(1)
• Karaman, A.(1)
• Kırbağ, Sevda(1)
• Niinomi, M.(1)
• Oflaz, Mücahit(1)
• Omaç, Basri(1)
• Pıhtılı, Güzin(1)
• Sen, A.(1)
• Torğut, Gülben(1)
• Torǧut, G.(1)
• Yazdıç, F.C.(1)
• Yilmazer, H.(1)
• Yilmazer, Y.(1)

• MakaleAçık Erişim2025Scopus SJRQ2/r/munzur/836
  Investigation of anticorrosive and antibacterial properties of electrochemically modified AISI430 steel surfaces; [Elektrokimyasal yöntem ile modifiye edilmiş AISI430 çelik yüzeylerin antikorozif ve antibakteriyel özelliklerinin incelenmesi]

  Açar, Gülistan; Cihangir, Salih; Omaç, Basri; Aydoğdu, Hacı Mehmet; Oflaz, Mücahit

  Both pharmacological and material-based approaches aim to slow bacterial evolution toward resistance. In this context, imparting specific antibacterial properties to materials is essential. Traditionally, alloying was a method to equip entire metals with antibacterial features, such as incorporating small amounts of copper (Cu) and/or silver (Ag). However, due to the high cost and inherent limitations of alloying, surface modification processes have gained prominence. Recent antibacterial studies on copper have led to the application of Cu(Ag) electrochemical coatings on AISI430 steel surfaces. This study aims to combine copper’s antibacterial properties with enhanced corrosion resistance and surface hardness. The coatings were deposited using deep eutectic solvents, known for their environmentally friendly properties, followed by potentiodynamic analysis. Microstructural and phase distribution characteristics were examined through SEM-EDS analysis, while surface roughness was analyzed using profilometry. Transitioning from micro-disc electrodes to macro-scale AISI430 substrates, Cu(Ag) films containing 16% Ag demonstrated nanoscale roughness, approximately double the hardness, and superior corrosion resistance compared to conventional copper surfaces. Antibacterial tests compared the coated surfaces with untreated AISI430 steel. Results showed that Cu(Ag)-coated surfaces exhibited improved antibacterial properties. This study shows how Cu(Ag) electrochemical coatings can be used to make surfaces that are antibacterial, long-lasting, and resistant to corrosion.

  İncele
• MakaleYalnız künye2024Scopus SJRQ3/r/munzur/2189
  Development of a novel rare earth element doped chitosan-graft-poly(hydroxyethyl methacrylate) composite for biomedical applications: synthesis, characterization, drug delivery, and antibacterial properties

  Gürler, N.; Torǧut, G.; Yazdıç, F.C.; Karaman, A.; Karaaslan Ayhan, N.

  The films of chitosan-graft-poly(hydroxyethyl methacrylate) polymer (Ch—g-poly(HEMA)) doped with the rare earth element (REE) lanthanum (La content of 0, 0.2, 0.4, and 0.8 wt.%) were fabricated. The films were characterized by attenuated total reflectance Fourier transform infrared (ATR-FTIR) spectroscopy, scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM/EDS), thermogravimetric analysis (TGA), and powder X-ray diffraction (XRD) analysis. The films obtained were loaded with a model drug tetracycline by freezing/thawing method. The cumulative drug release properties of tetracycline were investigated. The release of tetracycline from the polymer matrix was carried out in phosphate-buffered saline (PBS) buffer (pH 7.4) at 37 °C. It was found that the REE-doped composite films had a retarding effect on tetracycline drug release compared to that of the undoped film. All tested composites regardless of the REE dopant content were found to be active against three Gram-positive and three Gram-negative bacterial strains used to assess the antimicrobial properties of the polymer composites. These findings demonstrated that lanthanum and tetracycline have a high affinity for the Ch—g-poly(HEMA) polymer and suggested a synergistic effect in the polymer—lanthanum—tetracycline system. The La3+-doped Ch—g-poly(HEMA) composite film can be used as drug carrier system in the biomedical field.

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  AtıfScopus4·WoS4·OpenAlex3

  İncele
• MakaleYalnız künye2023Scopus SJRQ1/r/munzur/2120
  In-vitro corrosion and surface properties of PVD-coated β-type TNTZ alloys for potential usage as biomaterials: Investigating the hardness, adhesion, and antibacterial properties of TiN, ZrN, and CrN film

  Ali, L.A.; Dikici, B.; Aslan, N.; Yilmazer, Y.; Sen, A.; Yilmazer, H.; Niinomi, M.

  In this study, the corrosion and surface properties of non-toxic and non-allergenic β-type Ti–29Nb–13Ta–4.6Zr alloys (TNTZ) coated with TiN, ZrN, and CrN layers using the PVD technique were investigated under in-vitro conditions. The coatings' hardness, adhesion resistance, and antibacterial properties were also studied, with a focus on their potential usage as biomaterials. The corrosion tests were conducted using potentiodynamic polarization, the hardness tests were conducted using the Knoop method, and the adhesion tests were conducted using pull-off tests. The wetting properties of the coatings were examined through contact angle and 3D morphological analysis. The coatings were characterized using SEM-EDS and XRD. The results showed that the adhesion resistance of all coatings was significantly higher than the expected adhesion strength for biomaterial coatings, while their corrosion resistance was higher compared to the uncoated alloy. Besides, the study demonstrates the potential of TiN, ZrN, and CrN coatings on β-type TNTZ for use as a biomaterial with desirable surface and antibacterial properties.

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  AtıfScopus29·OpenAlex27

  İncele
• MakaleAçık Erişim2020Scopus SJRQ2/r/munzur/3445
  Synthesis, and antimicrobial and anticancer activities of sodium acrylate copolymers

  Torğut, Gülben; Pıhtılı, Güzin; Erecevit Sönmez, Pınar; Erden, Yavuz; Kırbağ, Sevda

  This study was designed to synthesize poly(sodium acrylate-co-N-isopropylacrylamide) via aqueous free-radical polymerization using the 2,2′-azobisisobutyronitrile initiator system at 60°C. The structural characterization of the copolymer was determined by Fourier-transform infrared spectroscopy. The polymer was synthesized in two different ratios, namely, poly(NaAc-co-NIPA1:1) and poly(NaAc-co-NIPA2:1), to investigate whether it affects their antibacterial–antifungal activities and anti-tumour effects. When the antimicrobial activities of different proportions of the copolymer extracts prepared with pure water were examined using the agar disc diffusion sensitivity test (at 120 μL: 10.8 mg/µL), it was observed that they had effect at increasing rates against all the bacteria, yeasts and dermatophyte fungi such as Staphylococcus aureus COWAN 1, Staphylococcus cohnii ATCC 29974, Bacillus megaterium DSM 32, Bacillus subtilis ATCC 6633, Escherichia coli ATCC 25922, Klebsiella pneumoniae FMC 5, Pseudomonas aeruginosa DMS 50071 SCOTTA, Candida albicans FMC 17, Candida glabrata ATCC 66032, Trichophyton sp. and Epidermophyton sp. The results of this study revealed that the obtained copolymers have significant effects on the treatment of diseases. In addition, the anti-tumour activities of the poly(NaAc-co-NIPA1:1) copolymer on human breast (MCF-7) and ovarian cancer (A-2780) cell line were specified and it was determined that high doses of the copolymer showed anti-tumour effects on both types of cancer cell lines. Also, this article reviews its antimicrobial and anticancer activities that will be of help for future scientists.

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  AtıfScopus3·WoS3·OpenAlex6

  İncele