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Koleksiyondaki öğeler
- MakaleAçık Erişim2020Scopus SJRQ2A novel risk evaluation approach for frequently encountered risks in ship engine rooms
Başhan, Veysi; Demirel, Hakan; Gul, Muhammet
The purpose of this study is to evaluate risks which are frequently encountered in the engine room on-board. In this context, twenty common risks are assessed using the neutrosophic analytic hierarchy process (N-AHP) and trapezoidal fuzzy technique for order preference by similarity to ideal solution (TrF-TOPSIS). In maritime risk evaluation, since it is frequently required the linguistic assessment of decision-makers to achieve a robust risk assessment tool, neutrosophic sets and fuzzy sets are used together in this study. Neutrosophic sets represent real-world problems effectively by considering all aspects of decision-making situations, (i.e. truthiness, indeterminacy, and falsity). Therefore, AHP is integrated with neutrosophic sets to assign weights of risk parameters initially. Then, the encountered risks are prioritized by TrF-TOPSIS. Finally, preventative actions for the risks have been discussed. In conclusion of the study, it is shown that skin exposure to the fuels/oils, exposure to chemicals and exposure to high pressure and temperature liquids are the most important risks through the engine room on-board. This study both emphasizes the importance of preventing damage to crew in the risk assessment of ship engine rooms and aims to increase the level of safety control and minimize the potential environmental impacts of a ship's damage.
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İncele - MakaleYalnız künye2020Scopus SJRQ2Assessment of impact of α-Fe2O3 and γ-Fe2O3 nanoparticles on phytoplankton species Selenastrum capricornutum and Nannochloropsis oculata
Ates, Mehmet; Cimen, Isil C. C.; Unal, Ilkay; Kutlu, Banu; Ertit Tastan, Burcu; Danabas, Durali; Aksu, Onder; Arslan, Zikri
In this study, the impact of alpha-iron oxide (α-Fe2O3, 20-40 nm) and gamma iron oxide (γ-Fe2O3, 20-40 nm) nanoparticles (NPs) on phytoplankton species Selenastrum capricornutum and Nannochloropsis oculata was investigated Characterizations of the NPs were systematically carried out by TEM, dynamic light scattering, zeta potential, X-ray diffraction, SEM, and Fourier transformation infrared spectroscopy. Acute toxicity was tested between 0.2 and 50 mg/L for each NP for a period of 72 hours exposure. γ-Fe2O3 NP inhibited development of N oculata at the rate of 54% in 0.2 mg/L group with a high mortality rate of up to 82%. α-Fe2O3 NPs were less toxic that induced 97% mortality on N oculata at 10 mg/L suspensions. In contrast, α-Fe2O3 NP inhibited growth of S capricornutum strongly (73%) in 0.2 mg/L group. γ-Fe2O3 NPs showed similar growth inhibition (72%) on S capricornutum in 10 mg/L suspensions. Despite the differential effects, the results indicated acute toxicity of α-Fe2O3 and γ-Fe2O3 NPs on N oculata and S capricornutum.
AtıfScopus27WoS20OpenAlex25
İncele - Kitap BölümüYalnız künye2020NARX neural networks model for forecasting daily patient arrivals in the Emergency Department
Yucesan, Melih; Mete, Suleyman; Serin, Faruk; Celik, Erkan; Gul, Muhammet
Regarding measuring of service quality at the emergency departments (ED), essential parameters are length of stay (LOS) and waiting times. Patient arrivals, which is related to LOS and waiting times, is hard to forecast and is affected by many parameters. Therefore, authors employed a Nonlinear Autoregressive Exogenous (NARX) model for forecasting of ED arrivals. NARX models are used extensively in many applications that show non-linear and dynamic behavior, but as far as authors know, the NARX method has not yet been used in the forecast of ED arrivals before. In this study, calendar and climatic variables are defined as input parameters. Patient Arrivals is defined as output parameter. A commercial software, MATLAB, was used to train and test the data set. To find the best network architecture Levenberg- Marquardt (LM) and Bayesian Regularization (BR) algorithms, different lags, and number of neurons were tested. R-squared and mean square error (MSE) are used to evaluate the accuracy of the tested networks.
AtıfScopus2OpenAlex4İncele - BildiriYalnız künye2020Performance Evaluation of Different Window Functions for Audio Fingerprint Based Audio Search Algorithm
Uyanik, Hakan; Koseoglu, Murat
Window functions are structures that are frequently used to increase the quality of the transformation when processing the signal in the time-frequency domain, especially when creating the spectrogram of the signal. In calculations for frequency information, Fourier transforms of short-time samples of the signal are transformed into spectrogram data with the help of window functions, and then operations are performed by using these data. In this study, the performance of three different window functions, which are used in obtaining spectrogram data in the algorithm developed for audio fingerprint-based audio recognition, have been tested under different artificial noise conditions. The results of these three different window functions were compared graphically, and a truth table was obtained based on the analyzed database. As a result of the simulations carried out in MATLAB, it has been observed that the hanning window function gives better spectral results for different noise levels, and accordingly it produces better matching results compared to the other two window functions as reported in former studies on different applications. In addition, some improvements about window length have been added into algorithm to obtain better results.
AtıfScopus12OpenAlex10İncele - Derleme MakaleAçık Erişim2019Scopus SJRQ2A new direction in social network analysis: Online social network analysis problems and applications
Can, Umit; Alatas, B.
The use of online social networks has made significant progress in recent years as the use of the Internet has become widespread worldwide as the technological infrastructure and the use of technological products evolve. It has become more suitable to reach online social networking sites such as Facebook, Twitter, Instagram and LinkedIn via the internet and web 3.0 technologies. Thus, people have shared their views on many different topics and their emotions with other users more widely on these platforms. This means that a huge amount of data is created on platforms where millions of people connect with each other through social networks. Nevertheless, the development of computational paradigms at high speed and complexity with technological possibilities allows analysis of valuable data by means of social network analysis methods. Our goal for this paper is to present a review of novel and popular online social network analysis problems with related applications and a reference work for researchers interested in analyzing online social network data and social network problems. Unlike other individual studies we have gathered 21 online social network problems and defined them with related studies. Thus, this study is original by presenting an important source of research by explaining the problems of online social network and the studies performed in this area.
AtıfScopus172WoS113İncele - MakaleAçık Erişim2020Scopus SJRQ1Effect of trichlorfon on some haematological and biochemical changes in Cyprinus carpio: The ameliorative effect of lycopene
Mişe Yonar, Serpil; Yonar, M. Enis; Pala, Ayşegül; Sağlam, Naim; Sakin, Fatih
Trichlorfon (TCF) is an antiparasitic agent used in aquaculture to treat external parasites and it belongs to the chemical class of organophosphates. This study was conducted to investigate the ameliorating effects of lycopene on TCF-induced toxicity in carp by evaluating haematological parameters and oxidant/antioxidant status. Fish were randomly divided into seven experimental groups. These groups were arranged as follows: control (no treatment) group, corn oil group, lycopene (10 mg kg−1) group, TCF-I (11 mg L−1) group, TCF-I (11 mg L−1) plus lycopene (10 mg kg−1) group, TCF-II (22 mg L−1) group and TCF-II (22 mg L−1) plus lycopene (10 mg kg−1) group. At the end of 14 days administration, blood and tissue (liver, kidney, and gill) samples were collected. Haematological changes [red blood cell (RBC) and white blood cell (WBC) count, haemoglobin (Hb) concentration, haematocrit (Ht) level, and erythrocyte indices: mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), and mean corpuscular haemoglobin concentration (MCHC)] were determined in the blood samples, while antioxidant parameters [(malondialdehyde (MDA) and reduced glutathione (GSH) levels and superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities] were evaluated in the liver, kidney and gill samples. The results demonstrated that all the haematological parameters were significantly decreased in the TCF-I and TCF-II groups when compared to the control group. Notable increases in the tissue MDA levels were observed in the TCF-treated groups. In contrast, significant decreases were observed in the tissue SOD, CAT and GSH-Px activities and GSH levels in the TCF-I and TCF-II groups. However, simultaneous treatment with lycopene provided a marked normalisation of the haematological and oxidant/antioxidant parameters compared with the TCF-I and TCF-II groups. The findings show that dietary lycopene supplementation might be helpful in abrogation of TCF toxicity by changing haematological conditions and antioxidant status in fish.
AtıfScopus34WoS28OpenAlex31İncele - MakaleYalnız künye2020Scopus SJRQ2Assessment of Oxidative Stress on Artemia salina and Daphnia magna After Exposure to Zn and ZnO Nanoparticles
Ates, Mehmet; Danabas, Durali; Ertit Tastan, Burcu; Unal, Ilkay; Cicek Cimen, Isil Canan; Aksu, Onder; Kutlu, Banu; Arslan, Zikri
In this study, the effect of zinc nanoparticles (Zn NPs) and zinc oxide nanoparticles (ZnO NPs) on Artemia salina and Daphnia magna, the primary consumer organisms were investigated. In this sense, investigation of trophic transfer and ecological sustainability potentials among living things, such as fish and crustaceans that are at the top of the food chain were also aimed. Zn NPs in the size of 40–60 nm and 80–100 nm and ZnO NPs (10–30 nm) were administered to A. salina and D. manga (respectively in total 105000 and 14000 individuals) in seven groups (Control, 0.2, 1, 5, 10, 25 ve 50 ppm) with three repetitions for a period of 72 h. Intensive and possible misuse of nanoscale materials is one of the biggest threats to the environment and all living things worldwide. Therefore, the control mechanisms for the use of NPs need to be established.
AtıfScopus29WoS19OpenAlex32İncele - MakaleYalnız künye2018Scopus SJRQ3H-curvature tensors on IK-normal complex contact metric manifolds
Turgut Vanli, Aysel; Unal, Inan
IK-normal complex contact metric manifolds have some important properties. There are several applications of this kind of contact manifolds in theoretical physics. In this paper, we studied on H-curvature tensors for IK-normal complex contact metric manifolds. We have shown that there is no IK-normal complex contact metric manifold with constant sectional curvature and an IK-normal complex contact metric manifold is not Ricci semi-symmetric.
AtıfScopus4WoS2OpenAlex3İncele - MakaleYalnız künye2020Scopus SJRQ1Gamma and neutron shielding characterizations of the Ag2O–V2O5–MoO3–TeO2 quaternary tellurite glass system with the Geant4 simulation toolkit and Phy-X software
Aşkın, A.
Gamma and neutron shielding potential of the newly developed xAg2O-(35-x)[0.5V2O5-0.5MoO3]-65TeO2 (x = 0, 5, 10, 15, 20 and 25 mol%) quaternary tellurite glass system were investigated computationally by means of Geant4 Monte Carlo simulations and Phy-X software. Gamma ray shielding capabilities were studied via the mass attenuation coefficient (μm), transmission fractions (T), effective atomic number (Zeff), half value layer (HVL) and mean free path (MFP) parameters and for the photon energies of 0.284, 0.356, 0.511, 0.662, 1.173 and 1.330 MeV. Fast neutron removal cross-section (∑R) parameter of the glasses was calculated to assess the neutron shielding capabilities. The results of this study revealed that tellurite glass containing 25% moles of Ag2O has highest μm and Zeff and lowest T, HVL and MFP values due to the high atomic number of Ag. In this study it was also seen that the ∑R of the investigated glass system increases with the increase of Ag2O fraction and ∑R values of the studied glasses are higher than barite added concrete and close to the ∑R of the PbO added borate glasses.
AtıfScopus36WoS35OpenAlex37İncele - MakaleAçık Erişim2018Scopus SJRQ2A fuzzy AHP and electre method for selecting stabilizing device in ship industry
Demirel, Hakan; Balin, Abit; Çelik, Erkan; Alarçin, Fuat
Roll stabilizer systems are studied for different types of ships by many researchers. It is well known that roll motion is caused by external disturbances (wave,wind etc) and large roll motion can cause capsizing easily. In addition, undesirable roll motion effect badly crew performance and passenger comfort. So, roll reduction has an important role for all types of ships. In our study, we proposed a fuzzy AHP (Analytic Hierarchy Process) and ELECTRE (Elemination and Choice Translating Reality English) method for selecting the most effective roll stabilizing system for a trawler type fishing vessel. Alternatives and criteria in relation to the stabilizers are determined by experts’ experiences and literature review. This paper intends to give a comprehensive procedure for determining the most suitable roll motion stabilizing system of trawler for safety and efficiency fishing in the open literature.
AtıfScopus25WoS20OpenAlex27İncele - MakaleYalnız künye2020Scopus SJRQ2Synthesis and Characterization of Disodium Hydrogen Phosphate Dodecahydrate-Lauric-Palmitic Acid Used for Indoor Energy Storage Floor Units
Xu, Qian; Akkurt, Nevzat; Zou, Zhenwei; Liu, Yang; Feng, Junxiao; Yu, Chuqiao; Ding, Chong; Xiong, Yaxuan; Zhou, Jingzhi; Zang, Yong
Organic and inorganic phase change materials (PCMs) are considered potential materials for thermal energy storage (TES) with different phase change characteristics. In this study, a novel organic-inorganic composite phase change material (PCM) called disodium hydrogen phosphate dodecahydrate-lauric-palmitic acid (D-LA-PACM) was prepared. Expanded graphite (EG) was selected as the support material, and the novel organic-inorganic form-stable PCM called D-LA-PAPCM/EG was prepared using the vacuum adsorption method. Differential scanning calorimetry, Fourier transform infrared spectroscopy, X-ray diffraction, leakage testing, melting and solidification cycle testing, thermal conductivity testing, scanning electron microscopy observation of the micromorphology, and other characterization methods were used to study the micro structure and morphology, thermal physical parameters, thermal conductivity, stability of the PCMs, and the comprehensive material properties of D-LA-PAPCM under the composite action of EG. Results indicated that the melting and freezing temperatures and latent heats of D-LA-PAPCM/EG were measured to be 31.6°C and 34.3°C and 142.9 and 142.8 J/g, respectively. Although some of the lauric-palmitic acid (LA-PA) and disodium hydrogen phosphate dodecahydrate (DHPD) separated in the multiple porous structures of EG after 1000 cycles, they could still absorb and release latent heats independently, with D-LA-PAPCM/EG still exhibiting good thermal stability. The thermal conductivity of D-LA-PAPCM/EG was 1.361 W/(mK). Therefore, the material and thermal properties of the prepared D-LA-PAPCM/EG indicate that it could be well used as a feasible material for energy-saving phase change floor units in indoor TES systems.
AtıfScopus18OpenAlex18İncele - MakaleYalnız künye2020Scopus SJRQ3The anesthetic effects of 2-phenoxyethanol on Munzur trout fingerlings (Salmo munzuricus Turan et al., 2017) at different temperatures
Akgul, E.; Can, E.
In this study, the anesthetic effects of 2-phenoxyethanol (2-PE, with %99 purity, BASF, Germany) on Munzur trout (Salmo munzuricus., a native species) originated from Munzur stream have been studied. 300 fish with the average weight of 4.42±0.62 g and length of 8.10±0.60 cm were used. To determine the anesthetic effects of various concentrations of 2-PE on Munzur trout fingerlings, the experiments were performed in two different temperatures (13 ºC and 18ºC) and five different concentrations (0.1, 0.2, 0.3, 0.4 and 0.5 ml L-1). 2-PE was used in this study as an anesthetic agent. In the anesthetic processing we practiced in all concentrations, except for 0.1 ml L-1 of 2-PE, loss of reflex (S5) was determined between 68 sec and 276 sec, and total behavioral recovery (R3) was determined between 58 sec and 208 sec. Induction times of anesthesia varied with anesthetic concentrations, decreasing with the increases of 2-PE concentrations. On the other hand, recovery times increased with decreasing of anesthetic concentrations. The lowest effective dose was determined as 0.3 ml L-1 at the temperatures 13 ºC and 18ºC. In this study, first time optimum anesthetic doses of 2-PE were determined for fingerling specimens of Salmo munzuricus which is endemic to Munzur stream and has an importance for aquaculture.
AtıfScopus4WoS3OpenAlex1İncele - MakaleYalnız künye2019Scopus SJRQ1Assessment of hydraulic properties of technosols using Beerkan and multiple tension disc infiltration methods
Yilmaz, Deniz; Bouarafa, Sofia; Peyneau, Pierre-Emmanuel; Angulo-Jaramillo, Rafael; Lassabatere, Laurent
The increasing global urban sprawl requires large amounts of materials, putting huge pressure on numerous natural resources. In particular, vast quantities of soils are used to create infrastructures or green spaces associated with new developments. Alternative solutions aimed at alleviating soil consumption are thus being encouraged. Creating urban soils by recycling waste from industrial and construction activities is feasible, but apart from their support function the resulting technosols should also be able to provide some ecosystem services such as the capacity to infiltrate water and filter contaminants. Various methods are routinely used for in situ characterization of the hydraulic behaviour of natural soils, but their ability to assess the hydraulic properties of technosols remains unclear. Indeed, technosols formed from recycled waste differ markedly from natural soil because they often contain a considerable proportion of coarse artefacts that affect their structure. In this study, results obtained by two distinct methods (ponding and tension infiltrometry), associated with two data processing methods (Beerkan estimation soil transfer (BEST) and numerical inversion), on a set of infiltration data measured on experimental plots made of technosols have been compared with each other. Both methods provided similar results and thus proved to be reliable when applied to technosols. Highlights: Reuse of by-products from anthropogenic activities is crucial to alleviate the consumption of natural soil. Hydraulic properties of technosols must be monitored to assess some of the ecosystem services they can provide. BEST and numerical inversion of multiple tension disc infiltration data gave consistent results. Reliability of the hydraulic characterization methods used for technosols deserves further inquiry.
AtıfScopus10WoS10OpenAlex12İncele - MakaleAçık Erişim2021First Clinical Placement: Nursing Students’ Views
Korkmaz, Fatos; Tarakcioglu Celik, Gul Hatice; Kucukkelepce, Gulhan Erkus; Arslan, Sevda; Gul, Senay
Objective: Analyzing students’ experiences about clinical practice will help instructors prepare learning settings where students can have more positive experiences. The purpose of this article is to identify nursing students’ views regarding their clinical placement. Method: This descriptive study was conducted with fresher’s in a nursing department of university during spring term of the 2014-2015 academic year in Ankara/Turkey. The data was collected with the question forms prepared by the researchers after the final exam of the “Fundamentals of Nursing Course”. 253 students were provided questionnaires to answer, which were collected after completion. Results: Students mean age was 20.2; 85.4% of them were female and 40.3% of them choose this department for employment opportunities. Students evaluated professional competence and presence of nurses, as “Good” and “Very Good” (with 80% to 90%) and, communication between nurse and patient as “Moderate” and “Bad” (with 60%). Prejudices regarding clinical practice (with 38.7%), fear of making mistake (with 55.3%), prejudices toward clinical setting (with 58.5%), and grade anxiety (with 29.2%) were stated as factors that affect clinical learning negatively. Conclusion: Students’ learning was affected by healthcare professions especially nurses, they worked with, instructors as well as some factors stem from themselves (fear of making a mistake, grade anxiety).
AtıfScopus1WoS1İncele - MakaleAçık Erişim2018Scopus SJRQ3Preliminary study on age, growth and reproduction of mustelus mustelus (Elasmobranchii: Carcharhiniformes: Triakidae) inhabiting the gulf of Iskenderun, north-eastern mediterranean sea
Ozcan, Ebru Ifakat; Başusta, Nuri
Background. Shark populations within the eastern Mediterranean are declining due to overfishing. Unfortunately, our knowledge on the biology of sharks and specifically dogfishes within eastern Mediterranean is extremely limited due to the lack of landings. Mustelus mustelus (Linnaeus, 1758) is one of such deficiently known cartilaginous fishes and the relevant information on its age and growth in the eastern Mediterranean is missing. The understanding of growth and reproductive behaviour is important for management and conservation of this species. The presently reported study was intended to determine age, growth, and some reproductive parameters of Mustelus mustelus collected in the Gulf of Iskenderun, the north-eastern Mediterranean Sea. Materials and methods. In this study, a total of 155 Mustelus mustelus were caught in the north-eastern Mediterranean Sea between March 2012 and October 2015. Fish age was determined based on band counts of sectioned vertebrae. The periodicity of band pair formation was examined using the marginal increment analysis. Growth parameters for all specimens were then determined by fitting the observed and the length-at-age data using the von Bertalanffy Growth Equation. The size and age at which 50% of both sexes reached maturity was estimated by a logistic model for maximum likelihood process and the gonadosomatic index was determined. Results. The total length and weight of the specimens examined ranged from 44.3 to 162.6 cm and from 241.3 to 12 060 g, respectively. The presently reported study provides new maximum lengths (162.6 cm) for M. mustelus from the north-eastern Mediterranean. The fish studied represented age groups from 0 through 25. The observed sex ratio was 1 ÷ 1.04 (females ÷ males). Von Bertalanffy growth parameters were estimated to be L∞ = 195.13 cm, W∞ = 20 060 g, K = 0.06, and t0 = −4.27 for all specimens. Length–weight relation was found to be W = 0.0027L3.0054 (R2 = 0.98) and 95% confidence intervals of b = 2.936–3.075, t-test P < 0.05. All studied specimens of M. mustelus represented isometric growth (b = 3). Condition factor ranged from 0.148 to 2.87 for females and from 0.103 to 1.024 for males. The length at 50% maturity and the age at 50% maturity were 109 cm and 8 in females and 92 cm and 7 in males, respectively. It was observed that mean GSI values were low in September and July, reaching a maximum in January to February. Conclusion. The results of this study could give useful insight for management plans and conservation of M. mustelus in the Mediterranean coast of Turkey.
AtıfScopus13WoS10OpenAlex12İncele - MakaleAçık Erişim2018Scopus SJRQ2Optical solitons to the space-time fractional (1+1)-dimensional coupled nonlinear Schrödinger equation
Esen, Alaattin; Sulaiman, Tukur Abdulkadir; Bulut, Hasan; Baskonus, Haci Mehmet
This study reveals the dark, bright, mixed dark-bright, singular and mixed singular optical solitons to the space-time fractional (1+1)-dimensional coupled nonlinear Schrödinger equation by using the extended sinh-Gordon equation expansion method. The constraint conditions for the existence of valid solitons are given. Under the choice of suitable values of the parameters and the fractional values of α and β, the 2- and 3-dimensional graphs to some of the reported solutions are plotted.
AtıfScopus164OpenAlex191İncele - MakaleYalnız künye2019Scopus SJRQ2Apigenin as an effective anticancer natural product: Spotlight on TRAIL, WNT/β-catenin, JAK-STAT pathways, and microRNAs
Ozbey, Ulku; Attar, Rukset; Romero, Mirna Azalea; Alhewairini, Saleh S; Afshar, Behnaz; Uteuliev, Yerzhan Sabitaliyevich; Hanna-Wakim, Lara; Ozcelik, Beraat; Farooqi, Ammad Ahmad
Wealth of information gleaned from decades of high-impact research work; scientists have disentangled the complicated web of versatile regulators that underlie cancer development and progression. Use of structural biology approaches and functional genomics have helped us to gain new insights into complex nature of cancer, and it is now clear that genetic/epigenetic mutations, overexpression of oncogenes, inactivation of tumor suppressors, loss of apoptosis, and versatility of protein binding partners have contributory roles in carcinogenesis and metastatic spread. It is becoming progressively more understandable that reprogramming of gene expression during and nontranscriptional changes during cancer development and progression are initiated and controlled by deregulated signal transduction cascades, all of which collectively create an incalculable complexity. Data obtained through preclinical and clinical trials revealed that alterations in the targeted oncogenes and other downstream, and parallel pathways played a central role in the development of resistance against different therapeutics. Phytochemicals have regained limelight, and different natural products are currently being tested for efficacy in preclinical studies. Apigenin, a plant-derived flavonoid has considerable pharmacological value and is reportedly involved in the regulation of different signaling cascades. In this review, we have attempted to summarize rapidly evolving understanding of molecular biologists and pharmacologists about the potential of apigenin in the regulation of deregulated signaling pathways in different cancers. We have emphasized on the regulation of WNT/β-catenin and janus kinase/signal transducers and activators of transcription (JAK-STAT) pathways. We also comprehensively discuss how apigenin restored apoptosis in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-resistant cancers. The review also gives a snapshot of microRNAs (miRNAs) that regulate wide-ranging biological processes, and it is now clear that each miRNA can control hundreds of gene targets. Apigenin was noted to upregulate miR-520b and miR-101 in different cancers to inhibit tumor growth. Moreover, apigenin-induced apoptotic rate was significantly higher when used in combination with miR-423-5p inhibitors or miR-138 mimics. Better comprehension of linear and integrated signaling pathways will be helpful in effective therapeutic targeting of deregulated signaling pathways to inhibit/prevent cancer.
AtıfScopus65OpenAlex66İncele - MakaleYalnız künye2019Scopus SJRQ2Experimental investigation of transverse loading on composite panels coated with different gelcoat colors subjected to UV radiation and hygrothermal aging
Dogan, Akar; Arman, Yusuf; Ozdemir, Okan
This study focuses on the effects of hygrothermal and UV radiation aging on the reinforced epoxy composites coated with gelcoat. The aim of this study is to investigate the influence of gelcoat colors on the tensile properties, impact behavior and thermodynamic properties of the composite panels after the aging process has been performed. Two different gelcoat colors were chosen as black and yellow. Unidirectional E-glass fiber fabrics with an areal density 300 g m-2 as reinforcement and epoxy matrix were used. Vacuum-assisted resin infusion molding (VARIM) method was used to manufacture composite panels. The tensile test specimens were prepared according to ASTM standards. Tensile strength of both fiber and transverse directions, the impact perforation threshold, and stroge modulus of the aged samples decreased compared to unaged (virgin) samples. However, the drop in mentioned properties for coated materials is less than for uncoated materials, especially in yellow coated materials. The temperature of hygrothermal conditions significantly affected the perforation threshold. Moreover, the tensile strength in transverse direction in yellow samples decreased approximately 13%, while it decreased 23% in the black coated samples. Impact perforation threshold of unaged (virgin), uncoated, coated with yellow gelcoat and coated with black gelcoat is obtained to be 75, 57, 65 and 61 J, respectively.
AtıfScopus12WoS9OpenAlex11İncele - MakaleYalnız künye2020Scopus SJRQ1Assesment of the gamma and neutron shielding capabilities of the boro-tellurite glass quaternary containing heavy metal oxide using Geant4 and Phy-X/PSD database
Aşkın, A.
This survey was conducted to reveal the gamma and neutron stopping performance of the 30PbO–10ZnO—(60-x)TeO2—xB2O3 (x = 0, 10, 20, 30, 50% mole) glass quaternary. Gamma and neutron attenuation parameters including the linear attenuation coefficient (μ), transmission fraction (TF), half value layer (HVL), mean free path (MFP), effective atomic number (Zeff), exposure buildup factor (EBF) and fast neutron removal cross-section (∑R) were determined computationally using the Geant4 and Phy-X/PSD database tools and for photon energies ranging between 0.284 MeV and 2.510 MeV. It was found that increasing the B2O3 content from 0% to 50% mole and correspondingly decreasing the TeO2 content from 60% to 10% mole results in a degradation of μ by 18.2% and of Zeff by 28.6% at 0.284 MeV. Due to this decrease in μ and Zeff, the values of TF and HVL increased by 37.3% and 22.4% respectively. In the present study it was also observed that the density (ρ) of glass quaternary decreased with the decreasing content of TeO2, and that the density of glass has a remarkable effect on the photon attenuation characteristics. The Degradation of μ, Zeff, ρ and the increase of TF and HVL proves that the photon attenuation ability of the glasses investigated worsens with decreasing content of TeO2, as Tellurium's atomic number and atomic mass are high compared to those of boron. While the decrease of TeO2 weakens the photon attenuation performance, it was found that fast neutron attenuation increases as ∑R increases from 0.108 to 0.116 for the glass specimens containing 60% and 10% mole of TeO2 respectively.
AtıfScopus31WoS31OpenAlex33İncele - MakaleAçık Erişim2020Reviewing Phlomis rigida Labill From Turkey as a Antimicrobial Efficacy
Sönmez, Pınar Erecevit; Kirbağ, Sevda; Çakilcioğlu, Uğur
This work researched the inhibitory properties of the extract of Phlomis rigida Labill plant including chloroform on gram-negative and positive bacteria, yeasts and dermatophyta; the related plant is used for therapeutic purpose in public. For the disk diffusion method, this extract is effective on Pseudomonas aeruginosa that is one of the negative bacterias by 11.33 ± 0.57 mm inhibition areas. Regarding other bacterias, the effect of the related extract is so low in avoiding the improvement of Escherichia coli, Staphylococcus aureus and Bacillus megaterium by 8.33 ± 0.57 mm inhibition area. It has highly effective on Trichopyton sp. and Candida albicans that are from dermatophytes fungis and yeast by 16.33 ± 0.57 mm inhibition area. About yeast and dermatophytes fungi it has a remarkable impact on Candida glabrata (14.33 ± 0.57 mm inhibition area), Epidermophyton sp. (12.33 ± 0.57 mm inhibition area). Antimicrobial activity of this natural extract against all the microorganisms that were tested by MIC method by concentrations vary by 100 uL and 6.25 uL. Acording to this; the results showed good inhibitory effect with 6.25 μL for C. albicans, Trichophyton sp. with 12.25 μL for C. glabrata. In the other hand it is effective with 25 μL for P. aeruginosa, Epidermophyton sp. with 50 μL for E. coli, S. aureus, B. megaterium. Being used plants for medical purposes as from since the early ages show that these plants can be used as alternatives of available antibiotics; including important medical components is the other reason for being an alternative at the same time. Concerning results, P. rigida can be utilized as a therapeutic drug for the healing of infections caused by microorganisms. In this study, we believe that the P. rigida is important in the search for new antibiotics and will contribute to the literature and the world of drug as it affects different types of microorganisms at the lowest level for the first time.
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