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Koleksiyondaki öğeler
- MakaleYalnız künye2019Scopus SJRQ1Deep long short-term memory networks-based automatic recognition of six different digital modulation types under varying noise conditions
Daldal, Nihat; Yıldırım, Özal; Polat, Kemal
In this paper, a new method based on deep learning has been proposed in order to recognize noise-digital modulation signals at varying noise levels automatically. The 8-bit data from six different modulations have been obtained by adding noise levels from 5 to 25 dB. The used digital modulation types are Amplitude Shift Keying, Frequency Shift Keying, Phase Shift Keying, Quadrature Amplitude Shift Keying, Quadrature Frequency Shift Keying, and Quadrature Phase Shift Keying. To recognize the noise-digital modulation signals automatically, a new deep long short-term memory networks (LSTMs) model has been proposed and then applied to these signals successfully. A significant advantage of the proposed system is that deep learning method has been trained and tested with raw digital modulation signals without applying any feature extraction from the signals. In this study, the noise modulation signals of 5–25 dB have been classified and compared with each other. The innovative aspect of the study is to classify the modulation with the LSTM method without dealing with the extraction of signal characteristics. Without noise, added digital modulation signals had been classified as the success rate of 97.22%, while with all noise-added signals have been classified as the success rate of 94.72% with deep LSTM model. The experimental results show that the proposed deep LSTM model has been achieved remarkable results in recognition of noised six different modulation signals with a fully end-to-end structure.
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İncele - MakaleAçık Erişim2018Scopus SJRQ3The chemical and biochemical oxygen demand reduction by armillaria tabescens in malathion supplemented culture medium
Yildirim, N.; Erguven, G.O.; Adar, E.
The extensive use of pesticides for controlling insects has been widely used in agricultural activities. However, the indiscriminate use of the pesticides has inflicted serious harmful problems to humans in the ecosystem. Our study aims to evaluating the capacity of Armillaria tabescens to remove the chemical oxygen demand (COD) and biochemical oxygen demand (BOD5) at different concentration of malathion insecticide (50, 100 and 150 ppm) under agitated (130 rpm) submerged culture conditions at 27 °C after 8 and 15 days. According to our results, A. tabescens has achieved COD reduction as 52.39, 27.24, and 38.30% at concentration of 50, 100 and 150 ppm respectively on 15 days. The BOD5 reduction rates were found as 78.2, 74.76 and 81.26% at 50, 100 and 150 ppm concentration respectively at the end of the 15th days. At the end of this time period, the dried biomass of A. tabescens was weighted and we have suggested that malathion in medium reduced the biomass production compared the control group (Sabouraud dextrose broth + A. tabescens). Our experiments have focused that; A. tabescens could be an alternative and useful fungus for bioremediation of wastewater containing malathion insecticide.
AtıfScopus3WoS3OpenAlex4İncele - MakaleAçık Erişim2021Scopus SJRQ4Regulation of cell signaling pathways by Wogonin in different cancers: Mechanistic review
Butt, Ghazala; Ozbey, Ulku; Malik, Durrshahwar; Attar, Rukset; Youssef, Lara; Farooqi, Ammad Ahmad
Natural products have historically been invaluable as a premium source of therapeutic agents. Recent advancements in genomics and structural biology have portrayed a high-resolution landscape of the diversity of proteins targeted by pharmacologically active products from natural sources. Natural product research has generated valuable wealth of information and cutting-edge research-works have leveraged our conceptual knowledge altogether to a new level. Wogonin (5,7-dihydroxy-8-methoxyflavone) is an O-methylated flavone and has attracted noteworthy appreciation because of its ability to pharmacologically target plethora of cell signaling pathways in different cancers. In this mini-review, we have gathered scattered pieces of available scientific evidence to summarize how wogonin pharmaceutically targeted Wnt/β-catenin, JAK/STAT, VEGF/VEGFR and TRAIL-driven apoptotic pathways in wide variety of cancers. We have also critically analyzed how wogonin prevented carcinogenesis and metastasis in tumor-bearing mice. Although researchers have uncovered pleiotropic role of wogonin in the regulation of different oncogenic signaling cascades but there are visible knowledge gaps in our understanding related to regulation of non-coding RNAs by wogonin. Future studies must converge on the unraveling of additional drug targets for wogonin to achieve a fuller and realistic understanding of the chemopreventive properties of wogonin.
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İncele - MakaleAçık Erişim2018Scopus SJRQ1Topic recommendation for authors as a link prediction problem
Aslan, Serpil; Kaya, Mehmet
Recently, link prediction studies on large-scale and complex networks have particularly become the focus of interest for researchers in various scientific fields. Many complex networks created from the real-world data contain bipartite structure by nature. Bipartite networks are a kind of complex networks that represent the interactions between the different node groups. Almost all of the previous studies on link prediction in bipartite networks focus on using the properties of projection networks to predict the relations between the node pairs. In this study, a novel similarity-based link prediction method based on strengthening weighted projection is proposed to predict the potential links between the authors and the topics in the large-scale bipartite academic information network created from the real-world data. Since information loss occurs when bipartite networks are converted to unimodal networks, it should be noted that when making a link prediction in this paper, both the bipartite network and the information on strengthening unimodal network obtained from the bipartite network are used. To evaluate the proposed method, a bipartite network was first created from a real dataset consisting of authors and their work. Then the method was tested on this network. Experimental results demonstrate that it is possible to obtain faster and more accurate link prediction results by the proposed method.
AtıfScopus35WoS25OpenAlex34İncele - MakaleAçık Erişim2018Scopus SJRQ3Traditional honey production and bee flora of Espiye, Turkey
Karaköse, Mustafa; Polat, Ridvan; Rahman, M. Oliur; Çakilcioglu, Ugur
This paper presents potential honey bee plants in Espiye (Giresun) which can be considered as a guide for beekeepers and researchers. A total of 149 taxa belonging to 125 genara and 48 families were recorded as pollen and nectary sources for honey bee colonies at Espiye (Giresun) region. Among the recorded taxa 58 were Phanerophytes, 57 taxa Hemicryptophytes, 19 taxa Therophytes, 13 taxa Cryptophytes and 2 taxa Chamaephytes. Updated nomenclature along with the families, local names, life form, flowering period and ecological status have been furnished under 94 herbs, 28 shrubs and 27 trees.
AtıfScopus10WoS13OpenAlex18İncele - MakaleYayıncıda açık erişim2020Scopus SJRQ4Assessment of elemental content, antioxidant activity, and total phenolic content of vitis sylvestris gmelin
Ayhan, Nagihan Karaaslan
In this study, we determined the Cu, Fe, Mn, and Zn contents of Vitis sylvestris Gmelin using flame atomic absorption spectrometry (FAAS), and examined the antioxidant properties of Vitis sylvestris Gmelin using radical scavenging capacities and total phenolic content tests. We found the average elemental contents; Cu, Fe, Mn, and Zn as 1.506 ± 0.042 mg/kg, 0.796 ± 0.020 mg/kg, 2.333 ± 0.033 mg/kg, and 3.191 ± 0.262 mg/kg, respectively. When we examined the antioxidant activity tests applied to different extracts, we determined the highest extraction yield with the methanol extract. DPPH radical scavenging activity, ABTS radical scavenging activity, and total phenolic content values in methanol extract were determined to be respectively 3.957 ± 0.146 mg TEAC/g fw, 9.062 ± 0.273 mg TEAC/g fw, and 2.365 ± 0.028 mg GAE/g fw. When we evaluated the antioxidant activity and total phenolic content results for all extracts statistically, we determined that there was generally a statistically significant difference between each extract (p < 0.01). Vitis sylvestris Gmelin has high antioxidant content when considering the data obtained. Also, we determined that it is an effective candidate in the protection against reactive oxygen species.
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İncele - MakaleYalnız künye2019Scopus SJRQ1Combined boron, radiogenic (Nd, Pb, Sr), stable (C, O) isotopic and geochemical investigations of carbonatites from the Blue River Region, British Columbia (Canada): Implications for mantle sources and recycling of crustal carbon
Çimen, Okay; Kuebler, Corinne; Simonetti, Stefanie S.; Corcoran, Loretta; Mitchell, Roger; Simonetti, Antonio
This study reports the combined major, minor and trace element compositions, and stable (C, O), radiogenic (Nd, Pb, and Sr) isotopic compositions, and first δ11B isotopic data for the Fir, Felix, Gum, and Howard Creek carbonatites from the Blue River Region, British Columbia (Canada). These sill-like occurrences were intruded into Late Proterozoic strata during rifting and extensional episodes during the Late Cambrian and Devonian -Mississippian, and subsequently deformed and metamorphosed to amphibolite grade in relation to a collisional-type tectonic environment. The carbonatites at Fir, Gum, and Felix contain both calcite and dolomite, whereas the carbonatite at Howard Creek contains only calcite. The dolomite compositions reported here are consistent with those experimentally determined by direct partial melting of metasomatized peridotitic mantle. The combined major and trace element compositions and δ13CPDB (−5.37 to −4.85‰) and δ18OSMOW (9.14 to 9.62‰) values for all the samples investigated are consistent with those for primary igneous carbonate and support their mantle origin. However, these signatures cannot be attributed to closed system melt differentiation from a single parental melt. The initial Nd, Pb, and Sr isotopic ratios are highly variable and suggest generation from multiple, small degree parental melts derived from a heterogeneous mantle source. The δ11B values for carbonates from Felix, Gum, and Howard Creek vary between −8.67 and −6.36‰, and overlap the range for asthenospheric mantle (−7.1 ± 0.9‰), whereas two samples from Fir yield heavier values of −3.98 and −2.47‰. The latter indicate the presence of recycled crustal carbon in their mantle source region, which is consistent with those for young (<300 Ma) carbonatites worldwide. The radiogenic and B isotope results for the Blue River carbonatites are compared to those from contrasting, anorogenic tectonic settings at Chipman Lake, Fen, and Jacupiranga, and indicate that similar upper mantle sources are being tapped for carbonatite melt generation. The pristine, mantle-like δ11B values reported here for the Blue River carbonatites clearly demonstrate that this isotope system is robust and was not perturbed by post-solidification tectono-metamorphic events. This observation indicates that B isotope signatures are a valuable tool for deciphering the nature of the upper mantle sources for carbonates of igneous origin.
AtıfScopus28OpenAlex25İncele - MakaleAçık Erişim2020Scopus SJRQ2The Communication Skills and Empathic Tendencies of Nursing and Midwifery Students to Reproductive Pattern Section of the Care Plan
Kaplan Serin, Emine; Alp Dal, Nursel; İkde Öner, Özlem
The objective of this study is to determine the communication skills and empathic tendencies of nursing and midwifery students to sexuality/reproductive pattern section of the care plan. The sample of this descriptive cross-sectional study consists of 665 students studying in the midwifery and nursing department of a state university in Eastern Anatolia Region of Turkey and agreeing to participate in the study as volunteers. Data of the study were collected using “Descriptive Characteristics Form for Students”, “Communication Skills Assessment Scale (CSAS)” and “Emphatic Tendency Scale”. Obtained data were assessed by using number, percent, mean and standard deviation as well as Mann–Whitney U Test, Kruskal–Wallis Test, t test, ANOVA and Pearson correlation test. The average age of students participating in the study was 20.81 ± 1.80 years, and 53.8% of them expressed that the society they lived in had a restrictive perspective on the concept of sexuality. A great majority of students think that cultural structure and religious beliefs are significant factors in the formation of sexual taboos. The study found out that 64% of the students could not ask the questions in the reproductive pattern section of the care plan, most of them did not want to be asked it themselves, and 70.5% of them were uncomfortable with asking these questions due to privacy. Approximately fifty-six percent (56.1%) of students thought that the concept of sexuality did not fall within a nurse’s responsibilities. Approximately fifty-six percent (56.1%) of them did not want to focus on the subject more during courses. Average total score of students on CSAS was 98.74 ± 13.05, average total score on the emphatic tendency scale was 67.31 ± 7.98 and a positive correlation was found between both scores. In this study, it was detected that students left the sexuality/reproductive pattern section in the care plan empty, therefore they did not/could not handle a patient’s potential problems related to sexuality/reproductive pattern.
AtıfScopus5WoS4OpenAlex5İncele - MakaleAçık Erişim2018Scopus SJRQ3Anesthetic efficiency of 2-phenoxyethanol on broodstock of salmo munzuricus, a new trout species originating from munzur stream; [Munzur akarsuyu orijinli yeni bir alabalık türü olan salmo munzuricus’un anaç bireyleri üzerinde 2-fenoksietanol’ün anestezik etkinliği]
Can, Erkan; Başusta, Asiye; Karataş, Bilal
Salmo munzuricus is a newly-named species of trout that spreads through rivers flowing along the Munzur Valley National Park. The efficacy of anaesthetic 2-phenoxyethanol was evaluated in indigenous brown trout in the present study. Fish were divided into three weight classes: 100-200 g (W1), 200-400 g (W2) and 400-600 g (W3) and they were exposed to four concentrations of anaesthetic (0.2, 0.3, 0.4 and 0.5 mL L-1). The lowest induction time was identified in the group W3 while the highest one was in the group W1. The lowest recovery time occurred after 73.2±3.83 sec in the group W3 and the highest one was 136±31.46 sec in the group W1. The recovery times were increased with increasing the concentration of 2-phenoxyethanol in the group W1. However, recovery times in the groups W2 and W3 were significantly longer than observed in W1, generally. Besides, it was indicated that fish size affected induction times and recovery times. As a result of the present study, the most appropriate concentrations were determined as 0.4 mL L-1 at weights of 100-400 g while 0.5 mL L-1 at weights of 400-600 g for 2-phenoxyethanol in Salmo munzuricus broodstock.
AtıfScopus4WoS4OpenAlex1İncele - MakaleAçık Erişim2019Scopus SJRQ2Improvement of sperm motility of Oncorhynchus mykiss and Salvelinus fontinalis by L-tryptophan
Kocabaş, Mehmet; Kutluyer, Filiz; Ertekin, Özlem; Aksu, Önder; Başçınar, Nadir
Experiments were designed to test the influence of L-tryptophan supplementation of the extender on the sperm motility parameters and bacterial flora of brook trout (Salvelinus fontinalis) and rainbow trout (Oncorhynchus mykiss). The extender containing 0.3 M glucose in 10% Dimethyl sulfoxide (DMSO) was supplemented with 0, 0.5, 1, 2, and 4 mM L-tryptophan. Sperm samples stored for up to 12 days at 4°C for brook trout were motile while motility was not observed after six days of storage for rainbow trout. Diluted sperm samples were spread-plated onto Plate Count Agar (PCA) (Total Bacteria Count), Rose Bengal Agar (RBC) (Yeast-Mold Count), Violet Red Bile Dextrose (VRBD) (Enterobacteriaceae count) and Mannitol Salt Agar (MSA) (Micrococcus/Staphylococcus count) and counts were performed in duplicate and sampling occurred on day 0, 2, 4, 6, and 12 of cold storage. L-tryptophan supplementation of the extender yielded a positive effect, significantly prolonging sperm motility in S. fontinalis and O. mykiss compared to the control group (p < 0.05). The ideal results were obtained above a concentration of 0.5 mM for both species. Total bacteria count in fresh sperm (undiluted samples) was not detectable and not detected in sperm samples treated with different L-tryptophan concentrations. Yeast-mold, Enterobacteriaceae and Micrococcus/Staphylococcus were not detected from fresh and treated sperm brook trout and rainbow trout. On the basis of the results, L-tryptophan-based extender is useful for maintaining sperm quality in short-term storage. L-tryptophan had a negative effect on the bacterial flora. The results of the current study encourages further studies related to long-term storage and reproduction management. Abbreviations: DMSO: dimethyl sulfoxide; PCA: plate count agar; RBC: rose Bengal agar; VRBD: violet red bile dextrose; MSA: mannitol salt agar; SCA: sperm class analyzer; CFU: colony-forming unit.
AtıfScopus13WoS14OpenAlex13İncele - MakaleYalnız künye2018Scopus SJRQ1Comparative evaluation of toxicological effects and recovery patterns in zebrafish (Danio rerio) after exposure to phosalone-based and cypermethrin-based pesticides
Korkmaz, Volkan; Güngördü, Abbas; Ozmen, Murat
This study evaluated the toxic effects and recovery patterns in zebrafish (Danio rerio) after exposure to phosalone-based (PBP) and cypermethrin-based (CBP) pesticides. Initially, the 96 h LC50 values of the pesticides were calculated as being 5.35 µg of active ingredient (AI) L−1 for CBP and 217 µg AI L−1 for PBP based on measured concentrations. Accordingly, experimental groups were exposed to three sublethal concentrations of pesticides for 96 h, separately, and then zebrafish were transferred to pesticide-free conditions for 10 and 20 days recovery periods. Biochemical markers were assessed including carboxylesterase (CaE), acetylcholinesterase (AChE), glutathione S-transferase (GST), lactate dehydrogenase, glutathione peroxidase, catalase, alanine and aspartate aminotransferase (ALT, AST) activities after the exposure and recovery periods. Also, the pesticide concentrations in test water were quantified by high-performance liquid chromatography (HPLC) analysis. Our results showed that AChE and CaE activities were significantly inhibited and GST was induced by both pesticides after 96 h exposure. For PBP exposure, the decreases for GST induction and CaE inhibition showed a partial recovery in pesticide-free conditions. However, the decreases in AChE activity for CBP exposure and insufficient increases in same enzyme activity for PBP exposure after 20 days in pesticide-free conditions indicated that the projected recovery period was not enough to the recovery of AChE activities and for the improvement of fish health.
AtıfScopus56WoS50OpenAlex59İncele - MakaleYalnız künye2021Scopus SJRQ2Graphene-reinforced potato starch composite films: Improvement of mechanical, barrier and electrical properties
Gürler, Nedim; Torğut, Gülben
In this study, PSG composite films were prepared by casting method by adding graphene (G) to glycerol plasticized potato starch (PS) films. The structure and properties of the composite films were investigated attenuated total reflectance Fourier transform infrared (ATR-FTIR), X-ray analysis (XRD), and swelling capacity, total soluble matter, transparency, tensile strength, and electrical conductivity. When the G content of PSG composite films increased from 0% to 1%, tensile strength increased from 1.035 MPa to 1.681 MPa, but decreased to 1.175 MPa in composite films containing 2% G. It also increased electrical conductivity when the G concentration increased. Also, the G layers are among the PS films and their swelling and solubility properties are reduced. With increased G concentration, the light transmittance decreased and the films were more opaque. These improvements can refer to the interface interaction between PS and G.
AtıfScopus43WoS35OpenAlex39İncele - MakaleYalnız künye2019Scopus SJRQ2Influence of RE oxides (Eu3+, Sm3+, Nd3+) on gamma radiation shielding properties of lead fluoroborate glasses
Wagh, Akshatha; Sayyed, M.I.; Askin, A.; Özpolat, Özgür Fırat; Sakar, E.; Lakshminarayana, G.; Kamath, Sudha D.
Authors report the change in lead fluoroborate glass properties with change in RE2O3 (RE = Eu, Sm, Nd) chemical composition. The RE2O3 exhibited improvement in the radiation shielding properties of the glass samples. The gamma rays shielding capabilities of the samples were studied using the WinXcom software (for Eu2O3, Sm2O3 doped glasses) and Monte Carlo simulation (for Nd2O3 doped glasses). The results exhibited that the mass attenuation coefficient (μm), effective atomic number (Zeff), and half value layer (HVL) depends on the concentration of RE2O3 and addition of the same significantly increased the shielding capabilities of the glass samples against gamma rays. The increase in photon energy revealed the decrease in radiation shielding properties. The reported density and radiation attenuation properties of RE2O3 doped lead fluoroborate glasses are predominant in radiation shielding applications which will be useful in high strength structures. Of all the glass samples 2.5 mol% of Eu2O3, Sm2O3 and Nd2O3 doped glasses showed enhanced shielding properties.
AtıfScopus40OpenAlex41İncele - MakaleAçık Erişim2020Scopus SJRQ2Influence of vitamin E and vitamin E-selenium combination on arginase activity, nitric oxide level and some spermatological properties in ram semen
Ozer Kaya, Seyma; Gur, Seyfettin; Erisir, Mine; Kandemir, Fatih Mehmet; Benzer, Fulya; Kaya, Emre; Turk, Gaffari; Sonmez, Mustafa
The effects of vitamin E and vitamin E-selenium combination on seminal plasma arginase activity and nitric oxide level and some spermatological properties in rams were investigated in this study. For control group, animals were injected intramuscularly with physiological saline. For vitamin E group, rams were injected intramuscularly with 300 mg/ram vitamin E. For vitamin E + selenium group, animals were injected intramuscularly with 5 ml/ram vitamin E + selenium. The semen was collected by artificial vagina at 1st, 4th, 24th, 48th and 72nd hr after administration in each group. Significant decreases in seminal plasma arginase activity (at 1st, 24th and 48th hr), nitric oxide level (at 72nd hr) and abnormal sperm rate (at 1st, 24th and 72nd hr), and significant increases in semen volume (at 24th hr), semen mass activity (at 24th and 48th hr), sperm motility (at 24th, 48th and 72nd hr) and concentration (at 1st hr) were observed in vitamin E group compared with control group. Similarly, significant increase in semen volume (at 1st, 24th and 48th hr), mass activity, (at 48th hr), motility (at 48th and 72nd hr) and concentration (at 4th, 24th and 48th hr), and significant decrements in abnormal sperm rate (at 1st, 24th, 48th and 72nd hr), seminal plasma nitric oxide level (at 1st, 4th, 24th and 48th hr) and semen pH (at 24th and 48th hr) were detected in vitamin E + selenium group in comparison to the control group. As a result, it is suggested that vitamin E and/or vitamin E + selenium applications may improve reproductive performance.
AtıfScopus19WoS16OpenAlex19İncele - MakaleAçık Erişim2020Scopus SJRQ2Thermal studies and influence of the thermal decomposition on dielectric properties of a new coumarin copolymers
Biryan, Fatih; Pihtili, Güzin; Demirelli, Kadir
In this study, firstly 7-hydroxy-4-chloroethyl coumarin compound was synthesized in accordance with the literature (Peterson et al. in Macromol Chem Phys 202: 775–784, 2001). Then, this compound was reacted with acryloyl chloride to form the 4-(chloromethyl)-2-oxo-2H chromen-7-yl-acrylate) monomer. A series of copolymers were prepared using this monomer and n-butyl acrylate monomer. TGA analysis system was used to examine the thermal properties of homopolymers and copolymers. The activation energies were calculated for thermal decomposition of homopolymer and certain copolymers according to Flynn–Wall–Ozawa method. TGA measurements were taken at different heating rates and given comparatively. The glass transition temperatures of the copolymers were determined by DSC analysis and these results were given comparatively. For investigating the dielectric properties of copolymers, dielectric constant, dielectric loss factor, and ac conductivity values were calculated in the range of 100 Hz–20 kHz frequencies. The results were plotted as a function of frequency. In addition, dielectric behaviors of residues were determined after heating to the first decay temperature of the two-stage decay polymers and compared with the first states.
AtıfScopus6WoS6OpenAlex6İncele - MakaleAçık Erişim2018Scopus SJRQ1A practical application of human reliability assessment for operating procedures of the emergency fire pump at ship
Akyuz, Emre; Celik, Erkan; Celik, Metin
This paper aims to conduct a practical application for human reliability assessment during operating procedures of an emergency fire pump on-board ship. A systematic human error prediction is performed for designated tasks during operational procedures of the emergency fire pump since human error can be regarded as one of the major factors contributing accidents at sea. Hence, human reliability performance is evaluated to enhance fire safety management in operational level on-board ship. In the paper, marine-specific error producing conditions are adopted under fuzzy sets environment. To enhance consistency of research and minimise subjectivity during expert's judgement stage, the paper is supported with a dominance factor which is used to adjust the impact level of expert's judgments in the aggregation stage of the methodology. The outcomes of the paper provide valuable contributions to the safety managers and technical superintends to monitor fire safety management and crew reliability performance.
AtıfScopus44WoS38OpenAlex42İncele - MakaleAçık Erişim2021Scopus SJRQ3Lutein/zeaxanthin isomers regulate neurotrophic factors and synaptic plasticity in trained rats
Orhan, Cemal; Erten, Füsun; Er, Beşir; Tuzcu, Mehmet; Şahin, Nurhan; Durmaz Kurşun, Öznur Ece; Juturu, Vijaya; Şahin, Kazim
Background/aim: This study was conducted to elucidate the effects of lutein/zeaxanthin isomers (L/Zi) on lipid metabolism, oxidative stress, NF-κB/Nrf2 pathways, and synaptic plasticity proteins in trained rats. Materials and methods: Wistar rats were distributed into four groups: 1) control, 2) L/Zi: rats received L/Zi at the dose of 100 mg/kg by oral gavage, 3) exercise, 4) exercise+L/Zi: rats exercised and received L/Zi (100 mg/kg) by oral gavage. The duration of the study was eight weeks. Results: Exercise combined with L/Zi reduced lipid peroxidation and improved antioxidant enzyme activities of muscle and cerebral cortex in rats (p < 0.001). In the Exercise + L/Zi group, muscle and cerebral cortex Nrf2 and HO-1 levels increased, while NF-κB levels decreased (p <0.001). Also, L/Zi improved BDNF, synapsin I, SYP, and GAP-43 levels of the cerebral cortex of trained rats (p < 0.001). The highest levels of BDNF, synapsin SYP, and GAP-43 in the cerebral cortex were determined in the Exercise+L/Zi group. Conclusion: These results suggested that exercise combined with L/Zi supplementation might be effective to reduce neurodegeneration via improving neurotrophic factors and synaptic proteins, and oxidative capacity in the cerebral cortex.
AtıfScopus15WoS13OpenAlex14İncele - MakaleAçık Erişim2020On Quasi-Conformally Flat Para-Sasakian Manifolds
Ünal, İnan; Sarı, Ramazan
In this paper, we present some new results on invariant submanifolds of a para-Sasakian manifold under the quasi-conformally flatness condition. Firstly, we examine flatness of quasi-conformal curvature tensor on para-Sasakian manifolds. We prove that a quasi-conformally flat para-Sasakian manifold is an η-Einstein manifold. Also, we give some results on the sectional curvature of such manifolds. Secondly, we consider the invariant submanifolds of a quasi-conformally flat para-Sasakian manifold. We prove that a totally umbilical submanifold of a para-Sasakian manifold is invariant. In addition, we investigate curvature properties of such submanifolds and we show that a totally umbilical invariant submanifold of a quasi-conformally flat para-Sasakian manifold is an η-Einstein manifold. Finally, we work on the sectional curvature properties of an invariant submanifold of a quasi-conformally flat para-Sasakian manifold.
AtıfScopus1İncele - MakaleYalnız künye2019Scopus SJRQ1A new approach for arrhythmia classification using deep coded features and LSTM networks
Yildirim, Ozal; Baloglu, Ulas Baran; Tan, Ru-San; Ciaccio, Edward J.; Acharya, U. Rajendra
Background and objective: For diagnosis of arrhythmic heart problems, electrocardiogram (ECG)signals should be recorded and monitored. The long-term signal records obtained are analyzed by expert cardiologists. Devices such as the Holter monitor have limited hardware capabilities. For improved diagnostic capacity, it would be helpful to detect arrhythmic signals automatically. In this study, a novel approach is presented as a candidate solution for these issues. Methods: A convolutional auto-encoder (CAE)based nonlinear compression structure is implemented to reduce the signal size of arrhythmic beats. Long-short term memory (LSTM)classifiers are employed to automatically recognize arrhythmias using ECG features, which are deeply coded with the CAE network. Results: Based upon the coded ECG signals, both storage requirement and classification time were considerably reduced. In experimental studies conducted with the MIT-BIH arrhythmia database, ECG signals were compressed by an average 0.70% percentage root mean square difference (PRD)rate, and an accuracy of over 99.0% was observed. Conclusions: One of the significant contributions of this study is that the proposed approach can significantly reduce time duration when using LSTM networks for data analysis. Thus, a novel and effective approach was proposed for both ECG signal compression, and their high-performance automatic recognition, with very low computational cost.
AtıfScopus377OpenAlex388İncele - MakaleAçık Erişim2020Scopus SJRQ3Analysis of the correlations between visual mathematics literacy perceptions, reasoning skills on geometric shapes and geometry performances of pre-service mathematics teachers
İlhan, Aziz; Aslaner, Recep
In the study, the correlations between visual mathematics literacy perceptions, reasoning skills on geometrical shapes and geometrical performances of pre-service mathematics teachers were investigated. The study participants included 384 pre-service mathematics teachers, who were attending education departments in two universities located in Eastern and Southeastern Anatolia regions in Turkey. In the study, due to time and workforce limitations, convenience sampling method was preferred, and relational screening model was adopted. The study data was collected with visual mathematics literacy perception scale, reasoning skills on geometric shapes and geometry performance tests developed by the authors. Analysis of the correlation between the variables demonstrated that there was a moderate correlation between visual mathematics literacy perception and both the reasoning skills on geometrical shapes and the geometry performance, and there was a high correlation between the reasoning skills on geometric shapes and geometry performance. Primary model path analysis demonstrated that visual mathematics literacy perception had a moderate effect on reasoning skills on geometrical shapes and geometry performance. It was also determined that reasoning skills on geometric shapes had a strong effect on geometry performance. The findings of the path analysis conducted on the sub-dimensions revealed that all sub-dimensions had a moderate positive effect on reasoning skills on geometric shapes. It was also found that visual mathematics literacy perception had a moderate positive effect on visual perception, geometry knowledge, spatial intelligence and concretization sub-dimensions and geometry performance.
AtıfScopus5OpenAlex9İncele
