Yazarlar
- Can, Erkan(3)
- Can, Safak Seyhaneyildiz(3)
- Demir, Veysel(3)
- Kaya, Gokce(3)
- Sahilli, Yeliz Cakir(3)
- Yaman, Mehmet(3)
- Yildirim, Numan(3)
- Yildirim, Nuran Cikcikoglu(3)
- Akbulut, Gulcin Beker(2)
- Aksu, Onder(2)
- Ates, Mehmet(2)
- Aydin, Sevinc(2)
- Kaya, Armagan(2)
- Korkmaz, Meral(2)
- Kutlu, Banu(2)
- Tanyol, Mehtap(2)
- Yigit, Emel(2)
- Akbaba, Emel(1)
- Akdeniz, Ismail(1)
- Akgun, Mehmet Hanifi(1)
- Alatas, Mevlut(1)
- Altinterim, Basar(1)
- Asma, Dilek(1)
- Atar, Hasan Huseyin(1)
- Ates, Burhan(1)
- Avci, Halim(1)
- Aydinl, Sevinc(1)
- Barim-Oz, Ozden(1)
- Batan, Nevzat(1)
- Bayhan, Hurrem(1)
- Bayram, Dilek(1)
- Beker-Akbulut, Gulcin(1)
- Benzer, Fulya(1)
- Bin-Shafique, Sazzad(1)
- Bogatu, Coneliu(1)
- Cikcikoglu-Yildirim, Nuran(1)
- Cirik, Semra(1)
- Danabas, Durali(1)
- Danabas, Seval(1)
- Demir, Tugba(1)
Yayınlar
- MakaleYalnız künye2022APPLICATION OF RAINWATER HARVESTING TO MUNZUR UNIVERSITY CAMPUS AND EXAMINATION OF CONTRIBUTIONS
Korkmaz, Meral
The world is facing drought, and over time, water problems are becoming more serious. Agricultural land and green areas are gradually declining due to water scarcity. While the amount of available water is gradually decreasing, people's unnecessary use of water and water consumption are increasing. This, in turn, requires the accurate use of existing water resources and the realization of intelligent building systems as soon as possible. Despite this fact, none of the university's public buildings currently use systems such as the rainwater harvesting technique. The main aims of this research are to find effective results in terms of savings and to contribute to avoiding water shortages in the future. It is important today to immediately begin making future housing with these systems and to integrate these intelligent systems into public buildings, especially incorporating the latest technologies. In this study, the advantages of zero-energy built roofs and rainwater harvesting systems on the Munzur University campus are evaluated.
AtıfWoS1
İncele - MakaleYalnız künye2022ESSENTIAL OIL COMPOSITION OF ENDEMIC Hypericum ekerii FROM TURKEY AND CHEMOTAXONOMIC COMPARISONS
Yuce-Babacan, Ebru; Demirpolat, Azize
In our study, chemotaxonomic comparisons and essential oil composition of Hypericum ekeriNtice&Aytac (Hypericaceae) endemic to Turkey was studied for the first time. The composition of the essential oils of Hypericum ekerii was investigated and 45compounds were determined in total. GC and GC-MS analysis result showed a-pinene 18.73%, limonene 7.28%, caryophyllene oxide 6.71% and b-caryophyllene 6.47% as the majorcomponents. Based on the major chemical components, clusterinvestigated was applied for all the Hypericum species on Drosanthesection studied. With H. ekerii and all Drosanthesection species were grouped based on the presence of a specific compound and a dendrogram was created, and this section grouped the species into clusters. The chemical distribution of essential oil compounds in the genus pattern were discussed in means of natural products, major components and chemotaxonomy.
- MakaleYalnız künye2021FATTY ACID CONTENT AND FREE RADICAL SCAVENGING (DPPH) ACTIVITIES OF SOME OF BRYOPHYTES EXTRACTS
Aydinl, Sevinc; Alatas, Mevlut; Batan, Nevzat
In this study, DPPH and fatty acid contents were investigated of some taxa belonging to Neckeraceae (Alleniella complanata, Alleniella besseri, Exsertotheca crispa) and Hypnaceae (Hypnum cupressiforme, Hypnum resupinatum, Hypnum andoi) family collected from Kamilet Valley (Artvin-Arhavi) in 2017. DPPH free radical scavenging activity was determined according to the method developed by Brand-Williams et al. The fatty acids in extracts were analyzed via gas chromatography after transforming them into methyl esters. According to the obtained results, it was determined that the DPPH scavenging effects of taxa from Hypnaceae family were significantly higher than those of taxa from Neckeraceae family, and that the free radical scavenging effects of taxa from Hypnaceae family varied depending on the amount of extract. The saturated fatty acids content of the Neckeraceae and the unsaturated fatty acids of the Hypnaceae were found to be richer (p<0.001). The high DPPH activity in our study, especially in Hypnum species, suggested that Hypnum species were richer in terms of phenolic content. These compounds can be used in the pharmaceutical, cosmetic and food sectors, if both of these species are phenolic and fatty acid content can be obtained as pure.
AtıfWoS2İncele - MakaleYalnız künye2021TREND ANALYSIS OF THE EFFECT OF RAIN ON SOLAR ENERGY PRODUCTION IN A SUSTAINABLE FUTURE
Korkmaz, Meral
The greatest need of the modern world is energy. From production to consumption, energy has become essential in all areas. As fossil-derived energy production systems cause global warming and climate change, interest in renewable energy sources is increasing. Despite the pandemic, solar production has shown promising growth throughout the world. Turkey has been encouraging investments in renewable energy sources, especially solar energy, for the last 10 years. Feasibility studies before the installation of solar power plants are crucial for investors. As a result of feasibility studies, the cost of the investment and the depreciation period can be calculated. In this study, feasibility studies of the 474 kWp power plant in Samsun province were carried out with PVsyst program. Significant differences were found between the software results and the actual results of the solar plant built in Samsun province. Production losses between actual data and numerical data are thought to be related to meteorological data. There are numerous studies in the literature about PV software. However. current studies have not examined the effect of meteorological data of the region on the difference in production between PV software results and solar power plant production values. In this study, the Sen method was used to determine the precipitation trend by taking meteorological data from Samsun province. With this method, rainfall in Samsun province was seen to be on an upward trajectory. For this reason, in regions where there is a lot of precipitation; feasibility studies of solar power plants are falling by approximately 9 percent.
- MakaleYalnız künye2021ANTIOXIDANT ACTIVITIES AND SOME BIOCHEMICAL CONTENTS OF THE SEEDS OF THE OKUZGOZU AND BOGAZKERE (Vitis vinifera L.) GRAPE VARIETIES GROWN IN TURKEY
Aydin, Sevinc
The Vitis vinifera L. grape species is a fruit that is the most prevalently grown in the whole world and has economic significance. It is known that, due to its climate conditions, Turkey has rich resources in terms of Vitis vinifera L. With this study, we aimed to determine the phenolic, vitamin and fatty acid contents of the Okuzgozu and Bogazkere varieties of Vitis vinifera L. and see the effects of these contents on antioxidant activity. Fatty acids in the lipid extract were analyzed by gas chromatography after conversion into methyl esters. For flavonoid and vitamin analyses, a high-performance liquid chromatography device (HPLC-UV. Shimadzu) was used. Antioxidant activity was determined by Radical Scavenging Activity (DPPH) and Lipid Peroxidation (MDA) experiments, As a result of the study, some saturated and unsaturated fatty acid, phenolic compound and vitamin contents of the two varieties were obtained. It was observed that the amounts of unsaturated fatty acids, whose effects on antioxidant activity are known, in the Okuzgozu variety were significantly higher than those in the Bogazkere variety. The results on phenolic and vitamin compounds revealed higher amounts in the Okuzgozu variety in comparison to Bogazkere as in the case of fatty acids. The finding that these contents and antioxidant activity were in proportion suggested that the antioxidant effect of the Okuzgozu variety is higher. If the substances that provide this effect are correctly isolated from the plant, they may be used beneficially in both the food and pharmaceutical sectors.
- MakaleYalnız künye2021EFFECTS OF HEAVY METAL ON Tetraselmis chuii
Kutlu, Banu; Dorucu, Mustafa
We determined the toxic effects of seven metals. copper (Cu), manganese (Mn). zinc (Zn), cobalt (Co). molybdate (Mo), lead (Pb), and cadmium (Cd) on the microalgae Tefraselmis chuii (Butcher, 1959). We exposed 50 mL of cultivated microalgae (f/2 Gaillard) in the exponential growth phase. with three replicates, to concentrations of 0 (control). 0.1, 1.0, 5.0, 10, 25. and 50 g L of each metal for 72 hours. The cellular count was recorded daily to evaluate any potential lethal effects. An increase in cellular density was seen in the control treatment. All treatments exposed to metals showed a logarithmic increase in cell density within 48 hours, with a cellular decrease that became evident later on. This study result with an insignificant decrease at low concentrations of Cd, Pb, and Cu at 24 hour was probably attributed to their use as micronutrients at these low concentrations. The most lethal effect was observed with Cd treatment, which killed 50% of the microalgae population at a concentration of 0.62 mu g L-1. In this study, this concentration was three times lower than that of lead and mercury. while being ten times lower than that of cobalt and molybdate. To elucidate the adverse effects on seawater environments, the microalgae Tetraselmis chuii is recommended as a model species.
AtıfWoS3İncele - MakaleYalnız künye2021BIOCHEMICAL COMPOSITION AND ANTIOXIDANT PROFILE OF GEOGRAFICALLY LABELED KOHNU GRAPE (Vitis vinifera L.) CULTIVAR FROM TURKEY
Akbaba, Emel; Aydin, Sevinc; Sanyurek, Nesrin Karaca
Vitis vinifera L. is cultivated throughout the World including Turkey which is one of the largest producers of grape. Grape is consumed as fresh or dry fruit as well as used in the wine industry in which good quality of grapes are preferred. Grape is also a part of the traditional Mediterranean diet which is linked to a low risk of cardiovascular and degenerative diseases. Kohnu is a geographically labeled type of grape cultivated in the eastern cities of Turkey. In this study, Kohnu grapes harvested from two different cities of Turkey were compared through phenolic compounds, phytosterols, vitamins, fatty acids, and antioxidative properties. The concentrations of phenolic compounds in the sample from Elazig were obtained to be significantly higher as compared to the sample from Malatya. Especially vanillic acid was found to be much higher in Elazig samples. The concentrations of fatty acids especially palmitic acid, palmitoleic acid, oleic acid, and linoleic acid were obtained significantly higher in Elazig samples as compared to Malatya samples. Vitamin and phytosterol concentrations of the samples from Elazig were also determined as higher as compared to Malatya samples. Significantly higher antioxidant activity of Kohnu grape seeds from Elazig was obtained via DPPH radical scavenging activity and MDA levels. The antioxidant profile of Kohnu grape seeds of Elazig samples could be related to phenolic composition and vitamins.
AtıfWoS4İncele - MakaleYalnız künye2019Scopus SJRQ4THE EFFECT OF PENDIMETHALIN HERBICIDE ON ANTIOXIDANT SYSTEM IN SAFFLOWER
Beker-Akbulut, Gulcin
Pendimethaline is a dinitroaniline herbicide compound which selectively controls weeds. It is a cell division and growth inhibitor. In this study, pendimethalin herbicide was applied to Dincer and Remzibey cultivars of Carthamus tinctorius L. in 0.004-0.01 M concentration range after germination. The effects of pendimethalin upon peroxidase (POD), ascorbate peroxidase (APX), superoxide dismutase (SOD), catalase (CAT) reduced glutathione (GSH), glutathione reductase (GR), glutathione-Stransferase (GST) and total phenolic content were investigated on the 24, 48 and 72 hours following the treatment. POD, APX, SOD, CAT and GST activities were increased on the 24, 48 and 72 hours in Dincer while decreased at 72 hour in Remzibey. GSH and GR activity were decreased at 72 hour in Dincer and Remzibey. Total phenolic content decreased at 48 and 72 hours in Dincer and Remzibey. In this study, we determined that pendimethalin herbicide affected the antioxidant enzyme activities in Dincer and Remzibey.
AtıfWoS1İncele - MakaleYalnız künye2019Scopus SJRQ4THE TOXIC EFFECT OF CADMIUM ON HUMAN ERYTHROCYTES AND NAC'S PROTECTIVE ROLE
Sahilli, Yeliz Cakir
The toxic effects cadmium (Cd), which is a heavy metal, on human erythrocytes and protective effects of N-acetyl-L-cysteine (NAC) on lipid peroxidation and antioxidant enzymes were investigated. The effects of 1, 50, 150 mu M doses of cadmium and 1mM NAC on the level of malondialdehyde (MDA) in human erythrocytes and superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) enzyme activities were investigated. When the Cd was applied alone, it was found that MDA level increased in erythrocytes and SOD, CAT and GPx activities decreased. No statistically significant difference was observed when 1mM NAC administered erythrocytes were compared with the control cells. However, the beneficial effect was seen only in administration doses of Cd at the levels of I and 50 mu M and NAC was observed to have a protective effect. As a result, NAC partially reduced the toxic effect caused by Cd on erythrocytes but could not completely prevent it.
- MakaleYalnız künye2019Scopus SJRQ4CHARACTERIZATION OF ERBIUM OXIDE NANOPARTICLES
Ates, Mehmet; Kar, Bulent; Bogatu, Coneliu
Considering the advantages of nanoscale materials such as being lighter, more robust, programmable materials, less material usage, less energy requirement during production phase, and no longer producing materials, it is important to produce nanomaterials and determine their properties. Therefore, the characterization of nanomaterials has become one of the pillars of material science. An important aspect of nanoscale material science is the method of characterization of materials that we use or study to learn more about them. In recent years, great importance has been given to rare earth materials with nanostructures. One of the rare earth elements is Erbium and it is one of the newly discovered materials that is used in high technology. Erbium oxide (Er2O3) nanoparticles (NPs) are used in electronic devices. It is used in capacitors, metal oxide semiconductor transistors, and as dopants for optical fiber and laser materials. In this study, Erbium based Er2O3 NPs were characterized. The characterization of Er2O3 was realized using X-ray diffraction (XRD), scanning electron microscopy (SEM), the energy dispersive X-ray (EDX), and Fourier transform infrared spectroscopy (FT-IR). The number of specific peaks and their position fit very well with those from standard XRD spectrum and revealed pure Er2O3 nano oxide. SEM analysis of these particles showed their spherical shapes that are in great extent uniform distributed with nano sizes ranged between 40-60 nm.
- MakaleYalnız künye2018Scopus SJRQ3SEASONALLY VARIATIONS OF ARSENIC SPECIES IN CHICKEN MEATS CONSUMED BY TURKISH PEOPLE WITH HG-AAS
Kaya, Gokce; Karaaslan, Nagihan M.; Yaman, Mehmet
The aim in this study is speciation and determination of arsenic in chicken meat matrix. For this purpose, chicken meat samples consumed commonly by Turkish people belonging to five different companies in Turkey were obtained from markets once per 15 days during 14 months. The samples were digested in microwave oven by using both nitric and hydrochloric acid. It was found that microwave digestion method can be used successfully in the speciation analysis of arsenic. The determination and speciation of As in solutions were carried out by hydride generation-atomic absorption spectrophotometry (HG-AAS). From the observed results, concentrations of As (V) were ranged between 3.0-14.0 ng g(-1) (mean 7.3 ng g(-1)) for breast tissues and 3.0-9.0 ng g(-1) (mean 5.1 ng g(-1)) for leg tissues. The concentrations of As (III) in all studied chicken tissues were found lower than the limit of detection (2 ng g(-1)).
AtıfWoS2İncele - MakaleYalnız künye2018Scopus SJRQ3ARTIFICIAL NEURAL NETWORKS AS NEW ALTERNATIVE METHOD TO ESTIMATING SOME POPULATION PARAMETERS OF TIGRIS LOACH (OXYNOEMACHEILUS TIGRIS (HECKEL, 1843)) IN THE KARASU RIVER, TURKEY
Ozcan, Ebru Ifakat; Serdar, Osman
In this study, a new method (Artificial Neural Networks) to estimating some population parameters of Tigris loach (Oxynoemacheilus tigris (Heckel, 1843)) collected between 2014 and 2015 in 14 different stations from Karasu River (East Anatolia, Turkey). The total length and weight of the species ranged from 62 to105 mm and from 1.7 to 10.9 g for females and 65 to 100 mm and from 2.4 to 9.8 g for males, respectively. The new maximum length for O. tigris was found to be 105 mm in this study. The length-weight relation of O. tigris was carried out with artificial neural networks (ANNs) and length-weight relationships (LWRs). The results obtained were compared. Length-weight relationships of O. tigris were found as W=0.0049*L-3.29 , R-2 =0.95 for all individuals. According to these values, the growth type of this species was positive allometric (b>3) for all individuals. Regression analysis showed that fish length has high significant correlation with weight (R=0.97, R-2 =0.95, F-1,F-185=31930.3, P<0.001). According to the comparison of the results obtained with MAPE (%), ANNs provide better results than the LWRs. The results of this study could give useful insight that ANNs can be evaluated as an alternative for length-weight relation estimation. The condition factor values (min-max) were observed as 0.680-1.239 for females and 0.699-1.074 for males. No studies have been done before on this species population parameters.
AtıfWoS15İncele - MakaleYalnız künye2018Scopus SJRQ3TIME-INDEPENDENT RHEOLOGICAL BEHAVIOUR OF PEANUT BUTTER: MODELLING AND ARTIFICIAL NEURAL NETWORK APPLICATION
Yogurtcu, Hakan
In this study, the rheological behaviour of semisolid peanut butter samples with a fat ratio of 42.7 % were examined in a temperature interval of 10-50 degrees C via rotational rheometer at different shear rates. Peanut butter samples display non-Newtonian yield-pseudoplastic behaviour. Seven model equalities were used for representing the time-independent rheological behaviour of peanut butter and the representation ability of the models were determined by way of determination coefficient (r(2)), mean absolute percentage error (MA%E), chi-square (chi(2)) and root mean square error (RMSE) statistical parameters. It was observed that the O'foli model was the most successful among the models applied to experimental data. Temperature dependency of viscosity at shear rates of 0.1, 0.4 and 0.75 s(-1) was determined via Arrhenius equality and activation energies varied between the interval of 46818.63-51952.52 J/mol. Three-layer model suggested for estimating viscosity using artificial neural network method was observed to be quite successful.
- MakaleYalnız künye2018Scopus SJRQ3THE EFFECTS OF MANNAN OLIGOSACCHARIDE (MOS) AND VITAMIN B12 ADDITIVES ON THE LIVER AND INTESTINE HISTOLOGY OF THE CARP FRY (CYPRINUS CARPIO L-1758)
Ates, Mehmet; Atar, Hasan Huseyin
In this study, four hundred (400) carp frys (Cyprinus carpio L. 1758) were fed for 90 days with commercial feed containing Mannan oligosaccharide (MOS) and Vitamin B-12. The effects of feeding with MOS and Vitamin B-12 additives in different proportions on the parameters on intestine and liver histology of the carps were studied. As a result of this particular study, no pathological disorder was observed in the liver cells based on histologic reviews. The villi in the intestine showed slight increase both in terms of length and thickness within the group fed with MOS, while the other groups fed without MOS showed no alteration for this particular organ.
- MakaleYalnız künye2017Scopus SJRQ3SEASONAL CHANGES IN ANTIOXIDANT DEFENCE SYSTEM ON BROWN TROUT (SALMO SP.) IN MUNZUR STREAM
Can, Erkan; Cikcikoglu-Yildirim, Nuran; Erdogan, Devrim
The aim of the present study was to evaluate the oxidant and antioxidant status of the indigenous brown trout (Salmo sp.) caught from Munzur stream (Tunceli, Turkey) at different seasons in different tissues. Glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD), total antioxidant status (TAS) and total oxidant status (TOS) levels were measured. These measurements were read in a microplate reader using commercial kits with ELISA method. At the end of the study, significant variations of oxidative stress biomarkers were observed between seasons and tissues. The results of this study show that oxidative stress responses in tissues of Salmo sp. are sensitive to the tissues and the seasons in relation to the contaminants, climatic parameters and reproductive period in Munzur stream. The selected parameters are in valuable biomarkers for monitoring of water systems since at molecular levels they give an early warning signal of xenobiotics on aquatic organisms. It was concluded that the measurement of antioxidants biomarkers known such as SOD, CAT and GSH-Px activities, TAS and TOS levels may also be promising indicators of an oxidant impact on aquatic organisms.
AtıfWoS2İncele - MakaleYalnız künye2017Scopus SJRQ3THE ROLE OF GLUTATHIONE IN THE DETOXIFICATION OF PERCHLOROETHYLENE
Sahilli, Yeliz Cakir
Environmental factors have important roles in the development of cancer. Especially, the exposure of chemicals existing in the workplace with people is a very important issue. People at such places are exposed to chemicals more especially via respiratory and dermal route. Thus, their health is under the risk. Dry cleaning centers are intensively subjected to PCE, which is a common chemical used at these work places, and the risk of cancer is very high for them. The main aim of the present study is to investigate, if PCE exposure results in glutathione efflux from human erythrocytes. In the present study, the changes in intracellular and extracellular non-protein sulfhydryl (NPSH) levels were determined in PCE exposed erythrocytes. PCE significantly depleted intracellular NPSH level in a time and concentration-dependent manner. PCE significantly increased the NPSH levels measured in the extracellular media. Along with the change in extracellular nonprotein thiol levels, significant increases in extracellular glutathione levels were detected. Erythrocyte membranes were not damaged over the course of PCE exposure as indicated by the absence of lactate dehydrogenase activity in the extracellular media. Utilization of MK571 an MRP inhibitor decreased the rate of glutathione efflux from erythrocytes suggesting a role for this membrane transporter in the process. The results of the present study indicate that erythrocytes efflux glutathione when exposed to PCE. In addition to glutathione oxidation, glutathione efflux also contributes to intracellular loss of glutathione when exposed PCE.
- MakaleYalnız künye2017Scopus SJRQ3C-REACTIVE PROTEIN AND ADRENOMEDULLIN LEVELS IN CAPOETA UMBLA (HECKEL, 1843) AS NOVEL BIOINDICATORS FOR BIOMONITORING THE MICROBIAL CONTAMINATION IN INLAND WATERS OF TUNCELI, TURKEY
Yildirim, Nuran Cikcikoglu; Danabas, Durali; Yildirim, Numan; Tanyol, Mehtap; Danabas, Seval
The present study focused on changes in the C-reactive protein (CRP) and adrenomedullin (ADM) levels in the liver and gill tissues of Capoeta umbla as biomarkers of environmental pollution and ecosystem health in inland waters of Tunceli (Turkey). The CRP levels in liver and gills were not significantly changed in March and September at every site (p>0.05) except for site 3 in gill tissues (p<0.05). The results of statistical analysis indicate that significant differences in CRP levels were found in liver and gills among sites (p<0.05), but no changes in the gills at March (p>0.05). In March, ADM levels in gills and liver were statistically changed among sites (p<0.05), while no statistical changes were determined in September (p>0.05). The results of this study indicated that CRP levels in the tissues of the C. umbla could be utilized as a significant bioindicator for disease pathogenesis in fish infections.
- MakaleYalnız künye2017Scopus SJRQ3SPATIAL AND TEMPORAL DISTRIBUTION OF PHYTOPLANKTON IN KARKAMIS DAM LAKE (SANLIURFA/TURKEY)
Sonmez, Feray; Kutlu, Banu; Sesli, Ahmet
The environmental factors that affect the seasonal change of the phytoplankton community and composition in Karkamis Dam Lake were investigated on samples taken from five stations between January 2015 and December 2015. It was found that the phytoplankton of Karkamis Dam Lake consisted of 85 taxa belonging to Bacillariophyta (56 taxa), Chlorophyta (15 taxa), Chrysophyta (1 taxon), Cyanophyta (10 taxa), Dinophyta (2 taxa) and Euglenophyta (1 taxon). Members of Bacillariophyta and Chrysophyta increased well during spring, summer and also at the end of fall whilst Chlorophyta grew well only in summer and fall. Cyanophyta became dominant at the end of spring and in summer. However Dinophyta was remarkably conspicuous in winter as well as in spring and fall in terms of prevalence. Excessive reproduction of Cyanobacteria, which is a characteristic aspect of mesotrophic lakes, was observed in Karkamis Dam Lake in both May and July. Results of physical and chemical measurements and analysis indicated that the lake was mesotrophic based on PCA and Carlson trophic state index. Phytoplankton composition was found to be affected by environmental factors such as temperature, pH, dissolved oxygen, phosphate and nitrate through the year. Using these data, a strong model was developed for sustainable management in Karkamis Dam Lake.
AtıfWoS3İncele - MakaleYalnız künye2017Scopus SJRQ3MONTHLY VARIABILITY OF OXIDANT AND ANTIOXIDANT BIOMARKERS OF FRESHWATER CRAYFISH (ASTACUS LEPTODACTYLUS ESCH., 1823)
Barim-Oz, Ozden; Yilmaz, Seval; Sahin, Hulya; Benzer, Fulya
In the present study was determined the effects of monthly variability on enzymatic antioxidant (superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px)), antioxidant (reduced glutathione (GSH)) and the oxidant status (nitric oxide (NO), lipid peroxidation (MDA)) in hepatopancreas, muscle, gills and gonad tissues of freshwater crayfish (A. leptodactylus) the monthly collected throughout the year from Keban Dam Lake of Turkey. Results indicate that variations in oxidants and antioxidants with relation to month were not only tissue specific but also were gender specific. The levels of oxidant parameters were generally higher in hepatopancreas in comparison to muscle, gills and gonad of crayfish. Moreover, in tissues were also determined the different oxidants and antioxidants responses in moulting, mating, breeding and egg laying periods.
AtıfWoS5İncele - MakaleYalnız künye2016Scopus SJRQ3ANTIMONY INDUCED GLUTATHIONE EFFLUX FROM HUMAN ERYTHROCTES
Sahilli, Yeliz Cakir; Akgun, Mehmet Hanifi; Yildiz, Deniz
Antimony is a trace element which has wide variety of industrial application. Antimony has recently been considered as an environmental pollutant. Among the inorganic forms, SbIII is the more toxic form. SbIII is ten times more toxic compared to the SbV. Consuming plants that are grown in antimony contaminated soil is one of the way by which humans are exposed to antimony. AsIII and SbIII forms strong bonds with free-SH groups. When SbIII or SbV interacts with proteins that contain free-SH groups, protein inactivation usually results in. Antimony may also result in free radical generation and induction of oxidative stress. Even though antimony has some applications in health as a drug, its biological effects have not been investigated in detail. In the present study we investigated the effects of SbIII on glutathione efflux in human erythrocytes. The effects of N-acetyl-L-cysteine on antimony induced glutathione oxidation and glutathione efflux were also investigated. Extracellular glutathione concentration significantly increased and reached to 0.033 +/- 0.0034 micromole/ml erythrocyte with 1 mM of potassium antimony tartrate in four hours. The control value of extracellular glutathione was 0.020 +/- 0.0035 micromole/ml erythrocyte. Our results show that SbIII treatment of erythrocyte results in glutathione efflux.
AtıfWoS2İncele