Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Ak, Gunes(1)
- Aksoy, Edanur(1)
- Arslan, Mehmet Enes(1)
- Aslan, Naim(1)
- Aydin, Derya(1)
- Bülbül, A.S.(1)
- Ceylan, Y.(1)
- Custodio, Luisa(1)
- Cziáky, Zoltán(1)
- Dikici, Abdullah(1)
- Erecevit Sönmez, Pınar(1)
- Glamocilja, Jasmina(1)
- Ilhak, Osman Irfan(1)
- Jekő, József(1)
- Kadi, Abdurrahim(1)
- Karadağ, A.(1)
- Korkmaz, N.(1)
- Korkmaz, Ş.A.(1)
- Kurt, Mustafa Şükrü(1)
- Mahomoodally, Mohamad Fawzi(1)
- Paksoy, Mehmet Yavuz(1)
- Pekdemir, Mustafa Ersin(1)
- Pereira, Catarina G.(1)
- Picot-Allain, Carene(1)
- Rodrigues, Maria João(1)
- Selçuk Pekdemir, Sibel(1)
- Sinan, Kouadio Ibrahime(1)
- Sokovic, Marina(1)
- Yazici, Ayşenur(1)
- Zengin, Gokhan(1)
- Çalicioglu, Mehmet(1)
- Çobanoğlu, Şeymanur(1)
- Öner, Sena(1)
- İmamoğlu, R.(1)
Yayınlar
- MakaleAçık Erişim2023Scopus SJRQ2Shape Memory Polymer-Based Nanocomposites Magnetically Enhanced with Fe3O4 Nanoparticles
Pekdemir, Mustafa Ersin; Aydin, Derya; Selçuk Pekdemir, Sibel; Erecevit Sönmez, Pınar; Aksoy, Edanur
This work aimed to investigate the effect of magnetic Fe3O4 nanoparticles (MNP), which are known to have a wide range of applications in recent years, on nanocomposite films prepared with shape memory polymers. Herein, PLA–PEG blend nanocomposite films were prepared by solution casting method using MNP at different ratios. PLA–PEG Blend/MNP nanocomposite films were characterized with Attenuated total reflection infrared spectroscopy (ATR-IR) to determine the –C=O stretching of PLA and Fe–O stretching signals of Fe3O4. The thermal stability, morphology, and magnetic behavior were studied by comparing the results among PLA–PEG blend, PLA–PEG blend/MNP nanocomposite with thermogravimetric analyses (TGA), differential scanning calorimetry (DSC), scanning electron microscopy (SEM), and a vibrating sample magnetometer (VSM), respectively. The effect of MNP on the shape memory properties of PLA/PEG blend was investigated. Moreover, the comparison of antimicrobial activity between PLA/PEG blend and PLA–PEG blend/MNP nanocomposite films were conducted by the disk diffusion method. The results showed that MNP increased the thermal stability of the PLA/PEG blend and the nanocomposites inhibited the growth of C.albicans microorganism. Graphical Abstract: [Figure not available: see fulltext.].
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İncele - MakaleAçık Erişim2022Scopus SJRQ4New dinuclear cyanido complexes with amine alcohol ligand: Synthesis, characterization and biotechnological application potential
Korkmaz, N.; Korkmaz, Ş.A.; Ceylan, Y.; İmamoğlu, R.; Bülbül, A.S.; Karadağ, A.
In this study, the cyanido complexes given by the formula [Ni(Abut)Ni(CN)4 ]·8H2 O (C1), [Cu(Abut)2 Ni(CN)4 ]·7H2 O (C2), [Zn(Abut)Ni(CN)4 ]·8H2 O (C3) and [Cd(Abut)Ni(CN)4 ]·7H2 O (C4) were ob-tained by microwave synthesis method. The powder forms of the complexes were characterized by elemental, FT-IR spectroscopy, and thermal analysis. And also antibacterial, antibiofilm and anticancer activities were investigated. The splitting stretching bands of cyanido groups in the FT-IR spectra of C1-C4 indicated the assets of terminal and end cyanido groups. The antibacterial activities of C1-C4 were tested with nine Gram negative and six Gram positive bacteria. The most efficient antibacterial activity of complexes was observed at 1000 µg/ml-1 concentration. Anticancer activity was tested using HeLa cell line and MTT test. The studied cyanide complexes have been shown to decrease the viability of HeLa cells with IC50 values 14.86, 6.5, 7.2 and 19.2 µg/ml for C1, C2, C3 and C4 complex, respectively.
- MakaleYalnız künye2022Scopus SJRQ2Structural, biocompatibility, and antibacterial properties of Ge–DLC nanocomposite for biomedical applications
Arslan, Mehmet Enes; Kurt, Mustafa Şükrü; Aslan, Naim; Kadi, Abdurrahim; Öner, Sena; Çobanoğlu, Şeymanur; Yazici, Ayşenur
Integrative production of new nanocomposites has been used to enhance favorable features of biomaterials for unlocking ultimate potential of different molecules. In the present study, advantageous properties of diamond like carbons (DLC) and germanium (Ge) like greater biocompatibility and antibacterial attributes were aimed to combined into a thin film. For this purpose, 400 nm DLC–Ge nanocomposite was coated on the borosilicate glasses via the magnetron sputtering and surface characteristics was analyzed by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and The Raman spectrum. Biocompatibility analysis were performed by 3-(4,5-Dimethylthiazol-2-yl) (MTT) cell viability assay and Hoechst 33258 fluorescent staining genotoxicity assessments on the human fibroblast cell line (HDFa). Finally, antibacterial properties of DLC–Ge nanocomposite coatings were investigated by Pseudomonas aeruginosa (ATCC 27853) and Staphylococcus aureus (ATCC 25923) bacterial attachment analysis. As a result of magnetron sputtering coating, nearly 400 nm thick DLC–Ge nanocomposite film showed a smooth, a non-porous, and a dense characteristic. Cell viability analysis showed that Ge–DLC coatings permits %95 cell surface growth of fibroblast cells. Also, there were no significant difference in aspect of nuclear abnormalities compared to the (−) control which showed nonmutagenic features of the thin film. Finally, antibacterial attachment analysis put forth that Ge–DLC coatings inhibits bacterial adhesion as %40 and %25 rates for P. aeruginosa and S. aureus bacterial strains, respectively. From these results, DLC–Ge nanocomposites could be proposed as a potential new biomaterial for various biomedical applications.
AtıfScopus20WoS16OpenAlex19İncele - MakaleYalnız künye2020Scopus SJRQ1Chemical profile, antioxidant, antimicrobial, enzyme inhibitory, and cytotoxicity of seven Apiaceae species from Turkey: A comparative study
Zengin, Gokhan; Sinan, Kouadio Ibrahime; Ak, Gunes; Mahomoodally, Mohamad Fawzi; Paksoy, Mehmet Yavuz; Picot-Allain, Carene; Glamocilja, Jasmina; Sokovic, Marina; Jekő, József; Cziáky, Zoltán
Several Apiaceae species, used as both food and in complementary and alternative medicine, represents a rich source of potential valuable phytopharmaceuticals which necessitates scientific contemplation. In the present study, the antioxidant, enzyme inhibitory, antimicrobial, and cytotoxic properties of methanol extracts of seven Apiaceae species, (Chaerophyllum macrospermum (Willd. ex Spreng.) Fisch. & C.A.Mey. ex Hohen, Ferula rigidula Fisch. ex DC., Ferula orientalis L., Prangos ferulacea Lindl., Prangos peucedanifolia Fenzl., Ferulago setifolia K. Koch, and Pimpinella anthriscoides Boiss.) were evaluated. Species belonging to the Prangos genus exhibited the highest total phenolic content, namely P. peucedanifolia and P. ferulacea, with values of 47.90 and 44.44 mg gallic acid equivalent/g extract, respectively. P. peucedanifolia also displayed the highest radical scavenging capacity (81.53 and 102.70 mg Trolox equivalent [TE]/g extract for 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid (ABTS), respectively) and reducing power (165.87 and 100.09 mg TE/g extract for cupric reducing antioxidant capacity (CUPRAC) and ferric reducing antioxidant power (FRAP), respectively). C. macrospermum showed the most potent inhibition against Alzheimer's disease related enzymes, namely acetylcholinesterase (4.53 mg galantamine equivalent [GALAE]/g extract) and butyrylcholinesterase (3.22 mg GALAE/g extract). P. ferulacea (131.94 mg kojic acid (KAE) equivalent/g extract) and P. peucedanifolia (4.97 mmol acarbose equivalent (ACAE)/g extract) were potent inhibitors of tyrosinase and α-glucosidase, respectively. In general, studied species were able to reduce cellular viabilities. P. peucedanifolia possessed promising antibacterial potential against Bacillus cereus (Minimum inhibition concentration (MIC): 0.37 mg/mL), L. monocytogenes (MIC: 0.56 mg/mL), P. aeruginosa and Escherichia coli (MIC: 0.27 mg/mL), Salmonella typhimurium and Enterobacter cloacae (MIC: 0.75 mg/mL). F. rigidula showed the highest antifungal effect against Aspergillus ochraceus and Trichoderma viride (MIC: 0.10 mg/mL). The present findings could be the scientific starting point towards the pharmaceutical and/or commercial utilization of these Apiaceae species.
AtıfScopus65OpenAlex64İncele - MakaleAçık Erişim2013Scopus SJRQ3Effects of essential oil compounds on survival of Listeria monocytogenes and Escherichia coli O157:H7 in cig kofte
Dikici, Abdullah; Ilhak, Osman Irfan; Çalicioglu, Mehmet
This study was undertaken to evaluate the effects of some essential oil compounds for the inactivation of Listeria monocytogenes and Escherichia coli O157:H7 in cig kofte. In experiment 1, a cig kofte batch was inoculated with high levels of E. coli O157: H7 or L. monocytogenes (7.00 log(10) cfu/g) and the batches were divided into 6 groups. Each group was treated with 18 mL/kg of normal saline, cineole, limonene, carvone, linalool, or eugenol. Treatment with carvone, linalool, and eugenol resulted in a significant (P < 0.05) decrease in the numbers of both pathogens. In experiment 2, the cig kofte was inoculated with the same pathogens and each group was treated with 0 (control), 20, 22.5, and 25 mL/kg of eugenol. Increases in concentration did not cause a difference in pathogen reduction. The results showed that eugenol, carvone, and linalool can be used for the inactivation of E. coli O157: H7 and L. monocytogenes in cig kofte or similar foods.
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