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- MakaleYalnız künye2026Scopus SJRQ2Drying temperature-dependent changes in grape seed bioactives and oxidative status: integrated HPLC/GC and multivariate analysis
Karaca Sanyürek, Nesrin
Abstract: Drying temperature (40–80 °C) critically influences the stability of bioactive compounds in grape seeds and their functional responses. In this study, we evaluated the vitamin and phytosterol content of Boğazkere grape seeds using high-performance liquid chromatography (HPLC) and the fatty acid content using gas chromatography (GC). Antioxidant capacity was determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and the oxidative stress marker, malondialdehyde (MDA). Temperature-dependent and compound-specific alterations were observed: while selected vitamins and phytosterols showed distinct thermal susceptibilities, fatty acid profiles exhibited measurable remodeling. Antioxidant activity revealed non-linear dose- and temperature-dependent patterns, whereas MDA consistently decreased with increasing temperature, reflecting the reduced oxidative metabolism in dehydrated tissues. Multivariate analysis, including principal component analysis (PCA) and heatmap visualization, effectively discriminated temperature treatments and revealed correlations between compositional and functional parameters. The combined use of univariate and multivariate analyses revealed that the drying temperature reshaped not only individual bioactive compounds but also the overall biochemical profile of grape seeds. These findings establish a mechanistic link between thermal processing and bioactive stability, providing a chemical basis for optimizing grape seed valorization in food systems.
- MakaleAçık Erişim2026Scopus SJRQ1Short-term effects of powerlifting-based training on hormonal, metabolic, and lipid profile markers in male basketball players: a randomized controlled trial
Tizar, Ercan; Erdoğan, Ramazan
Background: Powerlifting-based resistance training is increasingly incorporated into athletic conditioning programs; however, its short-term endocrine and metabolic responses remain insufficiently explored. Therefore, this study aimed to examine the short-term, exercise-induced changes associated with a powerlifting-based training program on selected hormonal, metabolic, and lipid profile parameters in male basketball players. Methods: This randomized controlled experimental study was conducted in accordance with CONSORT guidelines. Thirty male basketball players aged 18–24 years were randomly assigned to an exercise group (EG; n = 15) or a control group (CG; n = 15). Both groups continued their routine basketball training three days per week for six weeks, while the EG additionally performed a powerlifting-based training program. Serum concentrations of thyroid hormones (TSH, T3, and T4), insulin, glucose, growth hormone, testosterone, and lipid profile parameters were assessed before and after the intervention. Data were analyzed using two-way repeated-measures analysis of variance to evaluate group × time interactions. Results: Significant group × time interactions were observed for several biochemical parameters (p < 0.05). In the exercise group, insulin levels increased by 53.31%, while pre-exercise glucose levels under standardized conditions decreased by 14.46%. Thyroid hormones (TSH, T3, T4) increased by 45.26%, 18.85%, and 18.25%, respectively. Growth hormone and testosterone levels increased by 28.49% and 18.22%, respectively. In contrast, total cholesterol, LDL cholesterol, and triglyceride levels decreased by 2.49%, 4.28%, and 3.76%, respectively, while HDL cholesterol increased by 5.63%. No significant changes were observed in the control group. Effect size analyses indicated large interaction effects for key variables (e.g., insulin ηp² = 0.749; glucose ηp² = 0.757). The concurrent increase in insulin and decrease in glucose may reflect transient alterations in glucose–insulin dynamics rather than a direct improvement in insulin sensitivity. Conclusion: The inclusion of a powerlifting-based training program was associated with favorable short-term, exercise-induced changes in selected hormonal, metabolic, and lipid profile parameters in male basketball players. However, these findings should be interpreted with caution due to the limited sample size and intervention duration. Further studies employing larger cohorts and longer training periods are warranted to confirm these observations and to clarify their long-term physiological implications. Trial registration: ClinicalTrials.gov (NCT07398248), registered on 29/12/2025.
- MakaleYalnız künye2013Scopus SJRQ2Effect of Body Condition Score on Biochemical Milk Parameters having Economic Importance in Dairy Goat during the First Month of Postpartum Period
Cimen, Murat; Topcu, Hakan
The data were collected from 20 Turkish Saanen goats raised in Ismailli village of Tunceli Province during first four weeks of postpartum period. In the research, 10 goats having BCS 1 and 10 goats having BCS 2 were used. The dams in BCS 1 group had showed lower milk fat content as compared to dams in BCS 2 group until third week. The total solids and protein levels of goats did not differ between BCS 1 and BCS 2 groups during all weeks of research We found positive high correlations between total solids and protein (r=0.997; p<0.01) in BCS 1 group and BCS2 group (r=0.9998; p<0.01) Similar correlations were found for both BCS group in study. From our results, the lower BCS has negative significant influence on the milk fat synthesis for dams having low fat depots. (c) 2013 Friends Science Publishers
AtıfWoS7
İncele - MakaleYalnız künye2011Scopus SJRQ3Some Haematological and Biochemical Parameters in Common Carp (Cyprinus carpio L., 1758) in Munzur River, Tunceli, Turkey
Gulec, A. K.; Yildirim, N. C.; Danabas, D.; Yildirim, N.
Haematological parameters are indicators of the response of the animal to the environment and used as reliable indicators of fish health status to detect physiological changes following different stress conditions. This study was carried out to evaluate some haematological and biochemical parameters of Cyprinus carpio caught in Munzur River, Tunceli, Turkey. The values of total red blood cell count (RBC), haematocrit (HCT), haemoglobin concentration (HGB), mean corpuscular volume (MCV), mean cellular haemoglobin content (MCH), mean corpuscular haemoglobin concentration (MCHC), platelet count (PLT), mean platelet volume (MPV), plateletcrit (PCT), platelet distribution width (PDW) were measured. Levels of amylase, high-density lipoprotein cholesterol (HDL-C), cholesterol (CHOL), albumin (ALB), total protein (T-PROT), direct bilirubin (D-BIL), total bilirubin (T-BIL), gamma glutamyle tranferas (GGT), urea, creatinine, glucose (GLU), triglycerides (TRIG), uric acid (Uric-A), sodium, potassium, calcium, phosphorus and iron, chlorine were determined as 1.02 10(12)/L, 17.90 %, 11.72 g/L, 198.00 fL, 166.82 pg, 89.50 g/dL, 112.80 10(9)/L, 8.06 fL, 0.055 %, 17.59 fL, 87.20 U/L, 220.24 mg/dL, 767.40 mg/dL, 1.60 g/dL, 4.68 g/dL, 1.83 mg/dL, 3.046 mg/dL, 12.00 U/L, 9.20 mg/dL, 0.72 mg/dL. 504.40 mg/dL, 381.00 mg/dL, 2.76 mg/dL, 134.20 mmol/L, 1.90 mmol/L, 13.78 mg/dL, 17.96 mg/dL, 262.60 g/dL, 81.80 mmol/L, respectively. We assume that variation in values of blood indices may be a defensive mechanism against pollution.
AtıfWoS8İncele - MakaleYalnız künye2011Scopus SJRQ3Use of Biochemical Markers in Capoeta trutta (Heckel, 1843) for the Assessment of Aquatic Pollution in Munzur River, Tunceli, Turkey
Yildirim, N. C.; Danabas, D.; Ergin, C.
The potential utility of biomarkers for monitoring both environmental quality and the health of organisms inhabiting polluted ecosystems has received increasing attention during the recent years. In this study. it was aimed to investigate the possible effect of pollution on biochemical parameters of Capoeta trutta captured in two environments with different levels of pollution in Munzur River, Tunceli, Turkey. One of them, hereby named reference site, there is no sewage discharge. Other side is denominated as polluted site is characterized by discharge of domestic sewage. Levels of amylase, alkaline phosphatase, lactate dehydrogenase, high-density lipoprotein cholesterol, cholesterol, albumin, total protein, direct bilirubin, total bilirubin, gamma-glutamyl tranferase, aspartate aminotransferase, alanine aminotransferase, urea, creatinine, glucose, triglycerides and uric acid were checked in blood samples. Plasma biochemical changes showed significantly differences between reference and polluted sites in alkaline phosphatase, lactate dehydrogenase, high-density lipoprotein cholesterol, cholesterol, alanine aminotransferase and glucose values. These results indicate that both domestic waste water and agricultural activities can alter the serum biochemical contents of Copeata trutta fish in Munzur River. Continuous production of pollutants resulting in impaired ability to respond to different environment stress factors and diseases. Present groups of researchers suggest that pollution levels should be monitored regularly.
AtıfWoS3İncele - MakaleYalnız künye2010Scopus SJRQ3The Biochemical Parameters Having Economic Importance in Sheep and Fish Meats
Kayim, M.
In this study, 10 meat samples from fish (Trachurus trachurus L. 1758) and sheep (Akkaraman) were used. In the experiment, the used fish meat was a total body meat. However, the sheep longissimus muscle (lean) from 6th rib cut was sampled for determination of chemical components. The concentrations of total fat were lower (p < 0.01) for fish than sheep. However, the concentrations of pH were also lower (p < 0.05) for sheep material. There were no effects of animal species on the moisture concentrations. The rates of ash were lower (p < 0.01) for sheep group. The pH concentrations close to neutral in meat from fish may be advantage for eating quality. However, this pH level is disadvantage for shelf life of product. However, the high amounts of fat in the sheep meats may have a negative effect upon consumer's preference and health.
