Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Parlak Ak, Tuba(2)
- Yaman, Mine(2)
- Başak, Neşe(1)
- Gul Baykalir, Burcu(1)
- Gül Baykalir, Burcu(1)
- Karaaslan Ayhan, Nagihan(1)
- Ozer Kaya, Seyma(1)
- Pala, Aysegul(1)
- Saglam, Naim(1)
- Serdar, Osman(1)
- Seven, Ismail(1)
- Seven, İsmail(1)
- Silici, Sibel(1)
- Tatli Seven, Pinar(1)
- Tatli Seven, Pınar(1)
- Yonar, M. Enis(1)
- Yonar, Serpil Mise(1)
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ2Protective Effect of Propolis Against Oxidative Damage Caused by Cyfluthrin Insecticide on Gammarus pulex
Serdar, Osman
This study aimed to investigate both the protective and therapeutic effects of propolis (PP) against pesticide-induced oxidative stress in aquatic environments. For this purpose, Gammarus pulex was exposed to 0.00 (control), 0.05, 0.1, and 0.2 ppm concentrations of cyfluthrin (CYF) to determine its toxic effects. To evaluate the protective effect of PP, 5 ppm of PP was added to each pesticide concentration. Samples were collected from all experimental groups after 24 and 96 hours under appropriate conditions. SOD activity decreased under CYF exposure but increased significantly after PP supplementation. Although CAT activity did not show significant changes with CYF alone, it increased in the presence of PP. GPx activity remained statistically unchanged under CYF exposure but increased following PP treatment. CYF exposure led to decreased GSH levels; however, PP did not significantly alter GSH levels. TBARS levels increased due to CYF, and this increase was alleviated by PP application.
- MakaleAçık Erişim2025Scopus SJRQ3Cu, Fe, Mn AND Zn CONTENTS IN PROPOLIS SAMPLES FROM MALATYA, TÜRKİYE AND HEALTH RISK ASSESSMENT; [MALATYA, TÜRKİYE ARI PROPOLİSİNDEKİ CU, FE, MN VE ZN İÇERİKLERİ VE SAĞLIK RİSK DEĞERLENDİRMESİ]
Karaaslan Ayhan, Nagihan
In this study, copper (Cu), iron (Fe), manganese (Mn) and zinc (Zn) contents of propolis samples obtained from five different districts of Malatya, Türkiye were investigated. Element contents were determined using flame atomic absorption spectrometry (FAAS). The concentration ranges of propolis samples taken from five different districts of Malatya province varied between 1.24 ± 0.06 mg/kg and 6.28 ± 0.02 mg/kg for Cu, 206.28 ± 21.50 mg/kg and 663.08 ± 55.24 mg/kg for Fe, 15.40 ± 0.17 mg/kg and 27.11 ± 1.83 for Mn, 39.36 ± 1.82 mg/kg and 52.57 ± 2.13 mg/kg for Zn. The results obtained for each district and element were evaluated in detail considering the estimated daily intake (EDI), recommended dietary allowance (RDA), provisional maximum tolerable daily intake (PMTDI) of these elements for adults. Moreover, hazard coefficient (HQ) was calculated for risk assessment and it was determined that HQ values for the studied elements in bee propolis from all districts were below 1.
- MakaleAçık Erişim2020Scopus SJRQ2Bee glue (propolis) improves reproductive organs, sperm quality and histological changes and antioxidant parameters of testis tissues in rats exposed to excess copper
Seven, Ismail; Tatli Seven, Pinar; Gul Baykalir, Burcu; Parlak Ak, Tuba; Ozer Kaya, Seyma; Yaman, Mine
This study was designed to determine the effects of propolis on the sperm quality, antioxidant and histological parameters in the testicular tissues of male Sprague Dawley rats exposed to excessive copper (Cu). In this aim, 24 rats were randomly divided into four groups as follows: the control, Cu, Propolis and Cu+Propolis. When compared to control group, Cu administration significantly decreased sperm motility and concentration, increased total abnormal sperm rate. It caused a significant induction the malondialdehyde (MDA), and reduction the superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH) in testicular tissues. Also, it caused loss, disorganisation and vacuolation of the germinal epithelium, oedema of the interstitial tissues, proliferation of the interstitial cells, spilled immature spermatogenic cells in the lumen of some seminiferous tubules. A large number of active caspase-3-positive stained apoptotic cells and a significant decrease in Johnsen's testicular score were determined. However, significant ameliorations were observed in all sperm characteristics, MDA, SOD, CAT, GSH, seminiferous tubules, number of apoptotic cells and Johnsen's testicular score in Cu+Propolis group. Our results showed that oral supplementation of propolis had curative effect on the sperm quality, antioxidant and histological parameters in the testicular tissues of male Sprague Dawley rats exposed to Cu.
AtıfScopus39OpenAlex39
İncele - MakaleAçık Erişim2018Scopus SJRQ3The protective effects of propolis and flunixin meglumine on feed intake, antioxidant status and histological parameters in liver and kidney tissues against excess copper in rats; [Ratlarda bakır fazlalığına karşı yem tüketimi, antioksidan durum ve karaciğer ile böbrek dokularının histolojik parametreleri üzerine propolis ve fluniksin meglümin'in koruyucu etkileri]
Tatli Seven, Pınar; Gül Baykalir, Burcu; Parlak Ak, Tuba; Seven, İsmail; Başak, Neşe; Yaman, Mine
This experiment was conducted to determine the protective effects of flunixin meglumine and propolis on feed intake, antioxidant status and histological parameters in kidney and liver tissues in rats exposed to excessive copper. In this study individually housed thirty-six male Sprague-Dawley rats were used. Animals were randomly divided into six groups; control, copper sulphate (500 mg/kg BW/day, gavage), flunixin meglumine (2.2 mg/kg BW/day, ip), propolis (100 mg/kg BW/day, gavage), copper sulphate+flunixin meglumine (500 mg/kg BW/day of copper sulphate by gavage and 2.2 mg/kg BW/day of flunixin meglumine, ip) and copper sulphate+propolis (500 mg/kg BW/day of copper sulphate and 100 mg/kg BW/day of propolis by gavage). The study demonstrated that body weight change in the copper sulphate+propolis group significantly ameliorated in comparison with copper group (P<0.01). Propolis and flunixin meglumine administration significantly decreased MDA levels in the kidney and liver tissues, and serum TNF-α levels (P<0.001). Propolis supplementation to rats who were also treated with copper significantly increased the superoxide dismutase, catalase and reduced glutathione activities (P<0.001). Flunixin meglumine and propolis treatments decreased the copper-induced degenerative and necrotic changes with the apoptotic cells in the liver and kidney tissues. In conclusion, propolis appeared to ameliorate the adverse effects on feed intake, liver and kidney tissues seeing in the copper treatment and, apparently caused by the copper toxicity, by scavenging the free radicals and increasing activity of antioxidants.
AtıfScopus10OpenAlex9İncele - MakaleAçık Erişim2015Scopus SJRQ1Trichlorfon-induced haematological and biochemical changes in Cyprinus carpio: ameliorative effect of propolis
Yonar, M. Enis; Yonar, Serpil Mise; Pala, Aysegul; Silici, Sibel; Saglam, Naim
Trichlorfon is among the most commonly used products to treat fish parasites in aquaculture. We investigated the effectiveness of propolis in alleviating the toxicity of trichlorfon on haematological and oxidant/antioxidant parameters in carp Cyprinus carpio. Fish were exposed to sublethal concentrations (11 and 22 mg l(-1)) of trichlorfon, and propolis (10 mg kg(-1) of fish weight) was simultaneously administered. At the end of 14 d administration, blood and tissue (liver, kidney, gill) samples were collected. Haematological changes (red and white blood cell count, haemoglobin concentration, haematocrit level and erythrocyte indices: mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration) were determined in the blood samples, while antioxidant parameters (malondialdehyde and reduced glutathione levels and superoxide dismutase, catalase and glutathione peroxidase activities) were evaluated in the liver, kidney and gill samples. Trichlorfon led to negative alterations in the haematological and antioxidant parameters investigated. The administration of propolis alleviated this effect and suggests that fish treated with trichlorfon improve their physiological status when fed a propolis-supplemented diet.
AtıfWoS46OpenAlex56
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