Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Aydin, Sevinc(2)
- Aydın, Sevinç(2)
- Erman, Orhan(2)
- Kaya, Tubay(2)
- Akbaba, Emel(1)
- Aydin, Sevinq(1)
- Erişir, Figen Erdem(1)
- Erman, Fazilet(1)
- Gonayli, Selahattin(1)
- Ince, M.(1)
- Ince, O. K.(1)
- Kaplan Ince, Olcay(1)
- Kirmizikaya, Gorkem(1)
- Okutan, Tuba(1)
- Sanyürek, Nesrin Karaca(1)
- Temizer, Ibrahim Akin(1)
- Turkoglu, S.(1)
- Unal, Ilkay(1)
- Yildirim, N. C.(1)
- Yilmaz, Okke$(1)
- Yilmaz, Okkes(1)
- Yılmaz, Ökkeş(1)
- Çakır, Atilla(1)
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ4Effectiveness of organic tomato (Solanum lycopersicum L.) extracts added to yeast Cell Culture against H2O2 Toxicity; [Eficácia de extratos de tomate orgânicos adicionados à cultivos de células de levadura contra la toxicidad por H2O2]
Gonayli, Selahattin; Temizer, Ibrahim Akin; Aydin, Sevinq; Kirmizikaya, Gorkem; Okutan, Tuba; Yilmaz, Okke$
Growing tomatoes in season and organically are an important factor in terms of carrying higher levels of antioxidant molecules. This study aimed to demonstrate the protective effect of extracts obtained from naturally grown tomatoes, which are widely used as food, against oxidative damage caused by hydrogen peroxide on yeast cells (Saccharomyces cerevisiae L.). Lipophilic vitamins, phytosterol content, gluathione and oxidised gluathione content were analyzed by Shimadzu brand high performance liquid chromatography, while fatty acid analysis was performed by Shimadzu GC 2010 Plus Gas Chromatography. Protein content was analyzed spectrophotometrically. The study groups were designed as control, hydrogen peroxide, tomato and tomato + hydrogen peroxide. In all groups added with hydrogen peroxide and tomato extract compared to the hydrogen peroxide group; it was observed that vitamin D2, α-Tocopherol, β-Sitosterol and Stigmasterol contents increased significantly. Again, it was observed that ergosterol level increased significantly in the D + hydrogen peroxide group compared to the hydrogen peroxide group. When the fatty acid analysis results were examined, it was determined that in all groups added to the cultured yeast with hydrogen peroxide and tomato extracts (except the B + hydrogen peroxide group), there were increases in 16:0, 16:1, n-7, 17:0, 17:1 and 18:0 fatty acid levels compared to the hydrogen peroxide group. On the other hand, when its effect on protein and gluathione levels was examined, more significant increases were determined in all groups with tomato extract addition compared to the hydrogen peroxide group. At the end of the study, it was observed that tomato extracts had positive effects against hydrogen peroxide toxicity in yeast cells, although at different levels in terms of fatty acid, vitamin and phytosterol contents.
- MakaleYayıncıda açık erişim2023Scopus SJRQ3Vitamin content and MDA levels of certain white grape varieties from different altitudes in Turkey
Akbaba, Emel; Aydın, Sevinç; Sanyürek, Nesrin Karaca; Çakır, Atilla; Erişir, Figen Erdem
Grapevine (Vitis vinifera L.) is regarded as one of the world’s most important fruit crops in terms of acreage and commercial worth. Grapes are used to make not only wine but also fresh fruit, dried fruit, and juice. The quality of grapes or wine is significantly affected by environmental factors such as altitude, soil type, and climate. In this study, the 5 white grape varieties (Ağın beyazı, Tahannebi, Kabarcık, Şilfoni, and Besni) grown at different altitudes (800 m, 1000 m and 1200 m) in Turkey were investigated for their vitamin, and phytosterol concentrations as well as lipid peroxidation content. Şilfoni grape harvested at 800 m was found to possess the lowest lipid peroxidation content. High altitudes, were found to reduce lipid peroxidation contents in the Ağın beyazı, Tahannebi, and Kabarcık strains. The highest stigmasterol (98.34 μg/g), and beta-sitosterol (86.90 μg/g) concentrations were found within Şilfoni grape variety harvested at 800 m. The highest vitamin D-2 and D-3 levels were found in Ağın beyazı (1.39 μg/g) and Kabarcık (4.13 μg/g) grape varieties, both harvested at 1200 m. Kabarcık grape, however, revealed the highest concentrations of R-tocopherol (63.09 μg/g) and alpha-tocopherol (24.13 μg/g) at 1200 m within the samples. The highest vitamin K-2 level was determined within the Tahannebi grape (15.44 μg/g) from 1200 m. It was observed that the vitamin and phytosterol concentrations of white grape varieties tended to increase, while the lipid peroxidation values tended to decrease at high altitudes, especially at 1200 m. This study also exhibited a strong relationship among Vitamin D3, R-tocopherol, and alpha-tocopherol in the studied white grape cultivars.
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İncele - MakaleYalnız künye2021ANTIOXIDANT ACTIVITIES AND SOME BIOCHEMICAL CONTENTS OF THE SEEDS OF THE OKUZGOZU AND BOGAZKERE (Vitis vinifera L.) GRAPE VARIETIES GROWN IN TURKEY
Aydin, Sevinc
The Vitis vinifera L. grape species is a fruit that is the most prevalently grown in the whole world and has economic significance. It is known that, due to its climate conditions, Turkey has rich resources in terms of Vitis vinifera L. With this study, we aimed to determine the phenolic, vitamin and fatty acid contents of the Okuzgozu and Bogazkere varieties of Vitis vinifera L. and see the effects of these contents on antioxidant activity. Fatty acids in the lipid extract were analyzed by gas chromatography after conversion into methyl esters. For flavonoid and vitamin analyses, a high-performance liquid chromatography device (HPLC-UV. Shimadzu) was used. Antioxidant activity was determined by Radical Scavenging Activity (DPPH) and Lipid Peroxidation (MDA) experiments, As a result of the study, some saturated and unsaturated fatty acid, phenolic compound and vitamin contents of the two varieties were obtained. It was observed that the amounts of unsaturated fatty acids, whose effects on antioxidant activity are known, in the Okuzgozu variety were significantly higher than those in the Bogazkere variety. The results on phenolic and vitamin compounds revealed higher amounts in the Okuzgozu variety in comparison to Bogazkere as in the case of fatty acids. The finding that these contents and antioxidant activity were in proportion suggested that the antioxidant effect of the Okuzgozu variety is higher. If the substances that provide this effect are correctly isolated from the plant, they may be used beneficially in both the food and pharmaceutical sectors.
- MakaleAçık Erişim2021Scopus SJRQ3The protective effects of lupine (Lupinus albus) fruit extract against to destructive effects of hyperglycemia in type I diabetic rats
Aydın, Sevinç; Kaya, Tubay; Erman, Orhan; Yılmaz, Ökkeş
Background: Lupinus albus is a member of the Fabaceae family. As a natural or cultivat-ed plant, Lupinus albus is distributed in Europe, the Balkans and Turkey, especially in Marmara and Aegean regions. The lupine is a nutritious and protective plant against diabetes. Objective: In the present study, the effects of Lupinus albus fruits on malondialdehyde (MDA), reduced glutathione (GSH), total protein, ADEK vitamins, and cholesterol values, which are the indi-cators of oxidative damage and antioxidant defense. In this regard, muscle, liver, renal, and brain tissues of STZ-induced type I diabetes rats were studied. Methods: The analyzes of ADEK vitamins and cholesterol levels in tissues were performed via Shimadzu HPLC device. The lipid peroxidation levels were measured at 532 nm in spectrophotome-ter. Determination of GSH was read at 412 nm against blank, and for the total protein levels Lowry method was applied. Results: According to the results obtained, it was determined that among the rats with induced type I diabetes, the group applied lupine fruit extract was found to have increased GSH level and decreased MDA levels in all the tissues. The protein values were increased in liver tissues but decreased in the other tissues. The level of vitamins was significantly increased in almost all the tissues in the diabetic group. Conclusion: In the present study, it was shown that the lupine reduced the devastating effects of type I diabetes by decreasing the fasting blood glucose and lipid peroxidation values and increasing the glutathione level in comparison to the diabetic group.
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İncele - MakaleYalnız künye2020Scopus SJRQ4The protective effects of golden berry (Physalis peruviana L.) extract against to the oxidative and destructive effects of type i diabetes in rats
Erman, Fazilet; Kaya, Tubay; Aydin, Sevinc; Erman, Orhan; Yilmaz, Okkes
Type I diabetes is known as insulin-dependent diabetes mellitus, and the most important factor playing role in its formation is the genetic predispo- sition. Physalis peruviana L. (Goldenberry) is a plant, which has strong antioxidant properties, from Solanaceae family and, because of its fructose con- tent, plays regulatory role in blood glucose level of diabetics. In this study, it has been investigated the effects of goldenberry on the malondialdehyde (MDA), reduced glutathione (GSH), total protein, vitamins A, D, E, and K, and cholesterol levels which are the indicators of antioxidant defense and the oxidative damages in serum, muscle, kidney, liver and brain tissues of the rats, on which type I diabetes was induced by STZ. According to the obtained results, among the rats with STZ-induced type I diabetes, it was ob- served that the level of glutathione (GSH) increased and the level of malondialdehyde (MDA) decreased in all of the tissues of rats given goldenberry extract, while significant decreases were determined in the levels of vitamins K-1, K-2, D-2 and D-3 in all of tissues (except serum), and there were also decreases in the level of α-tocopherol and cholesterol in tis- sues of muscle, liver and kidney. In this study, it was shown that the goldenberry decreased the destructive effects of type-I diabetes by decreasing the serum glucose and lipid peroxida- tion and increasing the level of glutathione. It is believed that the obtained results would be used in fol- low-up of diabetic patients and in early diagnosis of the disease in future.
AtıfScopus4İncele - MakaleYalnız künye2017Scopus SJRQ3Characterization of antioxidant activity, vitamins, and elemental composition of ciris (Asphodelus aestivus L.) from Tunceli, Turkey
Unal, Ilkay; Kaplan Ince, Olcay
Ciris (Asphodelus aestivus L.), which has been used for a wide range of medicinal purposes and is indigenous in Tunceli, Turkey, was collected from the eastern and western parts of the city. The goal of this study was to determine the vitamins, essential elements, and antioxidant activity of this natural product. The 2,2-diphenyl-1-picrylhydrazyl-hydrate radical scavenging activity, metal chelating activity, reducing power, total phenolics, and Vitamin A, Vitamin C, sodium, potassium, phosphorus, magnesium, calcium, copper, manganese, and zinc concentrations were determined in ciris extracts. The concentrations of Vitamin A, Vitamin C, and Mn of ciris from west Tunceli were higher than samples from the east.
AtıfScopus7WoS7OpenAlex8İncele - MakaleYalnız künye2013Scopus SJRQ3EVALUATION OF ANTIOXIDANT PROPERTIES, ELEMENTAL AND PHENOLIC CONTENTS COMPOSITION OF WILD NETTLE (Urtica dioica L.) FROM TUNCELI IN TURKEY
Yildirim, N. C.; Turkoglu, S.; Ince, O. K.; Ince, M.
Wild nettle (Urtica dioica L.) types were sampled from different geographical regions in Tunceli (Turkey) to determine their mineral, vitamin, phenolic contents and their antioxidant properties. The total phenol varied from 37.419 +/- 0.380 to 19.182 +/- 1.00 mg of GAEs g(-1) of dry nettle. The highest radical scavenging effect was observed in Mazgirt parting of the ways 7.5 km with 33.70 +/- 0.849 mg mL(-1). The highest reducing power was observed in the nettles from Mazgirt parting of the ways 7.5 km. Among the various macronutrients estimated in the plant samples, potassium was present in the highest quantity followed by calcium and phosphate. Kaempferol and resveratrol were not determined in some nettle samples but rutin levels were determined in all samples. Vitamin A concentrations were ranged between 13.64 +/- 1.90 and 5.74 +/- 1.00 (mg kg(-1) dry weight). These results show that Urtica dioica L. collected from Tunceli in Turkey could be considered as a natural alternative source for food, pharmacology and medicine sectors.
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