Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Bulut, Hasan(53)
- Baskonus, Haci Mehmet(52)
- Alataş, Mevlüt(39)
- Gul, Muhammet(39)
- Serdar, Osman(38)
- Güler, Ömer(37)
- Akkurt, Nevzat(31)
- Benzer, Fulya(30)
- Sulaiman, Tukur Abdulkadir(29)
- Yucesan, Melih(29)
- Zengin, Gokhan(29)
- Kocabaş, Mehmet(28)
- Topal, Murat(26)
- Batan, Nevzat(25)
- Kök, Mediha(25)
- Ezer, Tülay(24)
- Paksoy, Mehmet Yavuz(24)
- Yildirim, Ozal(23)
- Tekin, H.O.(22)
- Utku, Anıl(22)
- ALMisned, Ghada(21)
- Ince, Muharrem(21)
- Öbek, Erdal(21)
- Erten, Fusun(20)
- Aslan, Naim(19)
- Celik, Erkan(19)
- Yildirim, Numan(19)
- Cakilcioglu, Ugur(18)
- Dal, Murat(18)
- Dal, Nursel Alp(18)
- Sahin, Kazim(18)
- Özkaynak, Fatih(18)
- Aslan, Alper(17)
- Erata, Hüseyin(17)
- Orhan, Cemal(17)
- Ergen, Burhan(16)
- Tanyol, Mehtap(16)
- Demir, Yakup(15)
- Etli, Serkan(15)
- Işık, Erdem(15)
Yayınlar
- Kitap BölümüAçık Erişim2023Scopus SJRQ4The Effects of Knowledge Extraction Approaches on Cryptanalysis Studies and Analysis of the Success of Chaos-Based Countermeasures
Bürhan, Yücel; Özkaynak, Fatih
Each new approach and scientific progress provides many advantages and innovations from theory to practice yet, its disadvantages should be evaluated comprehensively from different perspectives. In this study, the effects of knowledge extraction approaches on the cryptanalysis process have been evaluated. It is known that the secret key of the encryption algorithm can be obtained by using knowledge extraction approaches, especially with application oriented attacks such as side channel analysis. It is known that chaotic masks can be used as a countermeasure to prevent the success of these attacks. In this study, side-channel analyzes of the chaos-based substitution box structures that have been proposed in recent years have been carried out. The side channel analysis results of the existing studies in the literature have been carried out for the first time in this study. The results obtained showed that the approaches in the field of knowledge extraction should be handled more comprehensively in the cryptanalysis processes, and also pointed out that a new evaluation criterion should be analyzed for future studies for chaos-based design studies.
AtıfScopus2OpenAlex2
İncele - MakaleAçık Erişim2023Scopus SJRQ1Effects of a Combination of Arginine Silicate Inositol Complex and a Novel Form of Biotin on Hair and Nail Growth in a Rodent Model
Demir, Betul; Cicek, Demet; Orhan, Cemal; Er, Besir; Erten, Fusun; Tuzcu, Mehmet; Ozercan, Ibrahim Hanifi; Sahin, Nurhan; Komorowski, James; Ojalvo, Sara Perez
The purpose of this study was to examine the effects of a combination of inositol-stabilized arginine silicate complex (ASI) and magnesium biotinate (MgB) on hair and nail growth in an animal model. Twenty-eight female Sprague–Dawley rats (8 weeks old) were randomized into one of the following groups: (i) group (control), shaved; (ii) group (ASI), shaved + ASI (4.14 mg/rat/day); (iii) group (ASI + MgB I), shaved + ASI (4.14 mg/rat/day) + MgB (48.7 μg/rat/day); and (iv) group (ASI + MgB II), shaved + ASI (4.14 mg/rat/day) + MgB (325 μg/rat/day). On day 42, compared with the control group, while hair density (p < 0.05, p < 0.01, and p < 0.0001, respectively) and anagen ratio (p < 0.01, p < 0.01, and p < 0.001) increased in the ASI, ASI + MgB I, and ASI + MgB II groups, telogen ratio decreased (p < 0.01, p < 0.01, and p < 0.001, respectively). In the molecular analysis, VEGF, HGF, and KGF-2 increased in the ASI (p < 0.01, p < 0.01, and p < 0.05, respectively), ASI + MgB I (p < 0.0001 for all), and ASI + MgB II (p < 0.0001 for all) groups when compared to the control group. FGF-2 (p < 0.01) and IGF-1 (p < 0.001) were found to be increased in the ASI + MgB I and ASI + MgB II groups. SIRT-1 and β-catenin increased in the ASI (p < 0.05 and p < 0.01), ASI + MgB I (p < 0.001 for both), and ASI + MgB II (p < 0.0001 for both) groups. Wnt-1 increased in the ASI + MgB I (p < 0.001) and ASI + MgB II (p < 0.0001) groups. In conclusion, the combination of ASI and MgB could promote hair growth by regulating IGF-1, FGF, KGF, HGF, VEGF, SIRT-1, Wnt, and β-catenin signal pathways. It was also established that ASI did not affect nail growth, whereas the MgB combination was effective using a higher dose of biotin.
AtıfScopus11WoS9OpenAlex11
İncele - MakaleAçık Erişim2023Scopus SJRQ4Deep Learning Based Classification for Hoverflies (Diptera: Syrphidae)
Utku, Anıl; Ayaz, Zafer; Ciftci, Derya; Ali Akcayol, M.
Syrphidae is essential in pollinating many flowering plants and cereals and is a family with high species diversity in the order Diptera. These family species are also used in biodiversity and conservation studies. This study proposes an image-based CNN model for easy, fast, and accurate identification of Syrphidae species. Seven hundred twenty-seven hoverfly images were used to train and test the developed deep-learning model. Four hundred seventy-nine of these images were allocated to the training set and two hundred forty-eight to the test dataset. There are a total of 15 species in the dataset. With the CNN-based deep learning model developed in this study, accuracy 0.96, precision 0.97, recall 0.96, and f-measure 0.96 values were obtained for the dataset. The experimental results showed that the proposed CNN-based deep learning model had a high success rate in distinguishing the Syrphidae species.
AtıfScopus3WoS3OpenAlex3TR Dizin1
İncele - MakaleAçık Erişim2023Scopus SJRQ3Evaluation of the spiritual care needs of risky pregnants from the perspective of the patient and the clinician: A qualitative research
Yüksekol, Özlem Doğan; Ulucan, Mihriban; Baltacı, Nazlı; Nazik, Feyza
Objectives: Being diagnosed with a risky pregnancy and complications developing during pregnancy cause both stress and uncertainty for women and their families, so women with risky pregnancies need spiritual care more. For this reason, this research was conducted to determine the spiritual care needs of risky pregnant women which require a multidisciplinary approach. Methods: The research is a phenomenological descriptive type of qualitative research. The study was completed with 20 participants, including 10 pregnant women who were hospitalized in the obstetrics and gynecology clinic and diagnosed with risky pregnancy, and 10 clinicians who were responsible for the care and treatment of pregnant women in the clinic. Data were collected using a semi-structured interview form. Data analysis was supported by the MaxQda 2020 Pro package program. Results: The two themes that emerged in this study are the perspectives of pregnant women and the perspectives of clinicians. Each theme is categorized as spirituality and spiritual care perceptions, spiritual care needs and experiences, and barriers to spiritual care. Conclusion: According to the findings obtained from the study, it is seen that the views of pregnant women and clinicians on spiritual care are similar. Supportive relationships and providing respectful maternal care are among the spiritual care needs of women with risky pregnancies, and these help to maintain the spiritual well-being of pregnant women.
AtıfScopus1WoS1OpenAlex1İncele - MakaleAçık Erişim2023Scopus SJRQ3New epiphytic bryophyte communities from Turkey; [Nove zajednice epifitskih briofita iz Turske]
Alataş, Mevlüt; Erata, Hüseyin; Batan, Nevzat; Ezer, Tülay
The epiphytic bryophyte vegetation of the Kümbet Plateau (Dereli-Giresun) was investigated. A total of 40 relevés taken from tree trunks in different vegetation periods of the year 2019 were analysed using multivariate analysis methods such as detrended correspondence analysis (DECORANA) and two-way indicator species analysis (TWINSPAN), and the Braun-Blanquet method was also applied. As a result, Frullanio tamarisci-Neckeretum pumilae Alataş, Ezer, Batan & Erata ass. nov. and Frullanio tamarisci-Neckeretum pumilae-isothecietosum alopecuroidis Alataş, Ezer, Batan & Erata subass. nov. were described as new syntaxa from Turkey. In addition, Ulotetum crispae -sanionietosum uncinatae was recorded for the first time from Turkey, while Ulotetum crispae was recorded for the second time from Turkey. These syntaxa were analysed in terms of their ecological and floristic aspects.
AtıfScopus1OpenAlex1İncele - BildiriAçık Erişim2023Chat with ChatGPT: Access to cultural heritage with ChatGPT
Yilmazer, Merve; Karakose, Mehmet
Cultural heritage, in the most general sense, refers to the historical accumulations from the past to the present. Digital systems are being integrated as an alternative to physical interventions for the management, maintenance and supervision of cultural heritage sites. For these purposes, advanced intelligent systems such as machine learning and deep learning are generally used. In this study, the competence of ChatGPT, an artificial intelligence robot developed by OpenAI with a high learning rate, in the field of cultural heritage is investigated. Questions such as cultural heritage, digital cultural heritage, protection of cultural heritage, etc. were asked to ChatGPT, and the timeliness and adequacy of the answers produced in response to the questions were evaluated. In addition, a comparison of experimental studies in the literature for the preservation and cultural heritage digitalization sites is also included in this study.
AtıfScopus6OpenAlex4İncele - MakaleAçık Erişim2023Scopus SJRQ2Internal deformation of continental blocks within converging plates: insights from the Ovacık Fault (Anatolia, Türkiye)
Zabci, Cengiz; Sançar, Taylan; Tikhomirov, Dmitry; Ivy-Ochs, Susan; Vockenhuber, Christof; Friedrich, Anke M.; Yazici, Müge; Akçar, Naki
The active tectonics of Anatolia is mostly characterized by its westward motion with respect to Eurasia between the Hellenic subduction in the west and Arabia-Eurasia continental collision in the east. Although most of the deformation is suggested to be confined along Anatolia’s boundary elements, viz. the North and East Anatolian shear zones, recent studies indicate a higher magnitude of internal strain accumulation, especially along the parallel/subparallel strike-slip faults of its central province. We present the first morphochronology-based slip rate estimate for one of these strike-slip structures, the Ovacık Fault, by using cosmogenic36Cl dating of offset fluvial deposits. At the Köseler Site (39.3643°N, 39.1688°E), two faulted risers, bounding the alluvial fan with its subplanar surface (NF1/NF1’) and the inset terrace tread (NF1/T2), are offset 19–24 and 15–22 m, respectively. The scattered surface ages and variability of 36 Cl concentrations in depth profiles suggest strong evidence for inheritance in alluvial fan and terrace deposits; thus, we used modelled depth-profile ages for both surfaces. The modelled ages 8–10 ka for NF1 and 6–8 ka for T2 yield slip-rate estimates 2.4 +0.5/–0.4 mm/a and 2.8 +0.7/–0.7 mm/a, respectively, for the upper-tread reconstruction of the NF1/NF1’and the lower-tread reconstruction of the NF1/T2. Our results together with previous slip-rate estimates for other structures show a significant internal deformation for Anatolia, especially along its subparallel strike-slip faults. These secondary faults slice Anatolia into several pieces giving rise to the formation of the Malatya-Erzincan, Cappadocian, and Central Anatolian slices, where the geometry is strongly controlled by the distribution of the Tethyan accretionary complexes.
AtıfScopus3OpenAlex3TR Dizin1İncele - MakaleAçık Erişim2023Scopus SJRQ3Synthesis, Characterization, Antimicrobial and Time Killing Activities of New SulfaDerived Schiff Bases Coordinated with Cu(II)
İdil, Önder; Şahal, Hakan; Canpolat, Erdal; Özkan, Mustafa
Synthesis of three Schiff bases of 5-bromo-3-nitro salicylaldehyde containing different sulfonamide group antibiotic compounds and their Cu(II) complexes was carried out. Structures of all compounds were characterized with spectroscopic methods, including Fourier transform infrared, proton nuclear magnetic resonance, and elemental analysis. The in vitro antimicrobial activity of ligands and complexes against Gramnegative and Gram-positive bacteria and the yeast Candida albicans was evaluated. It was determined that the ligand and complexes showed outstanding antimicrobial activity against almost all of the microorganisms tested. It has been observed that the newly synthesized complexes have more antimicrobial effects than the corresponding ligands. It has been determined that the newly synthesized complexes have more antimicrobial effects than the others (E. coli, L. monocytogenes, and C. albicans), especially on Staphylococcus aureus and Pseudomonas aeruginosa.
AtıfScopus4WoS3OpenAlex2İncele - MakaleAçık Erişim2023Scopus SJRQ1Investigation of Critical Raw Materials in Sludge of Municipal Wastewater Treatment Plant
Topal, Murat; Arslan Topal, E. Işıl
In the present research, lanthanum, vanadium, tungsten, scandium, bismuth, antimony, gallium, phosphorus, magnesium, and cobalt from critical raw materials (CRMs) were monitored for one year in the sewage sludges from an advanced biological wastewater treatment plant with the aim of presentation of possibility of using sewage sludge as a secondary source of critical raw materials. The amounts of the critical raw materials in sewage sludge were calculated annually, and economic values were revealed. Maximum concentrations of lanthanum, scandium, tungsten, bismuth, antimony, gallium, vanadium, cobalt, magnesium, and phosphorus were 4.3, 1.6, 0.5, 1.51, 1.27, 1.7, 23, 5.6, 6500, and 16,170 mg/kg, respectively. In the sewage sludge, the amount of CRMs, which have been formed annually, have been listed as tungsten < scandium < antimony < bismuth < gallium < lanthanum < cobalt < vanadium < magnesium < phosphorus. In autumn, summer, spring, and summer season, the mean highest concentration was for P, while the minimum concentration was for W. In sewage sludge, P and W elements were the highest and the least of the CRMs, respectively. With the recovery of CRMs in sewage sludge, the highest theoric achievable income is for Mg, while the lowest income is for Sb. It is determined that a total of 26,083.8 USD/year could be obtained by recovering the CRMs mentioned here from the sewage sludge.
AtıfScopus1WoS1OpenAlex3İncele - MakaleAçık Erişim2023Scopus SJRQ1Radiation mechanism on dissipative ternary hybrid nanoliquid flow through rotating disk encountered by Hall currents: HAM solution
Shamshuddin, M.D.; Akkurt, Nevzat; Saeed, Anwar; Kumam, Poom
The energy transition to enhance heat transport during the flow of ternary hybrid nanofluid comprised of Copper (Cu), Iron oxide (Fe3O4), Silicon dioxide (SiO2) nanoparticles and Polymer as base liquid over a revolving disk surface has been reported. From the several existing techniques, adding nanoparticles to standard working fluids is an effective approach that might dramatically improve the rate of heat transfer. The Hall and radiation impacts are also considered. A mathematical model is developed by assuming the flow as incompressible and purely radial in a cylindrical coordinate system and appropriate similarity variables are introduced for problem simplification and dimensionless analysis. The solution of complex generated PDEs was calculated using semi analytical method known as Homotopy Analysis Method (HAM) after translating them into corresponding ODEs. It has been observed that the consequences of thermal radiation, dissipation term, unsteadiness and rotation parameters boost the energy transmission rate and enhances the heat transfer rate of tri hybrid nanofluids. However, Cu-Fe3O4 nanoparticles in the base fluid remarkably magnifies the energy transmission rate. The unitary ternary hybrid nanofluid (Cu, Fe3O4, SiO2) has higher velocity profiles as compared to unitary nano fluid (Cu) and hybrid nano-fluid (Cu-Fe3O4).
AtıfScopus133WoS121OpenAlex138İncele - Derleme MakaleAçık Erişim2023Scopus SJRQ3Obtaining haploid plants by irradiated pollen culture in oil seed crops
Yaman, Hümeyra; Sanyürek, Nesrin Karaca
Haploid plant production is of great importance to shorten the breeding period in plant breeding programs. Obtaining pure lines in plant growing programs require an intensive work with huge labor and time. Obtaining one hundred percent homozy-gous pure lines is a key point for the improvement and development of new cultivars. Haploid plants with a single set of homozygous chromosomes have become a valuable tool in plant breeding. Dihaploid plants that are homozygous at all loci with dou-bling of their chromosomes can be propagated by seed and reach full homozygosity in a single generation. Traditional methods take seven years to reach homozygosity. Dihaploidization methods provide significant advantages in terms of gaining homozy-gosity in a short period of one year and bringing pure lines into agriculture. Anther culture and irradiated pollen technique are among the most widely used techniques in this respect; where physical or chemical agents are used to induce mutated pollen grains and anthers that are subsequently employed to develop dihaploids through in vitro cultures. These techniques are a good source to facilitate gene mapping, cyto-genetic research, and evolutionary studies. Irradiated pollen culture techniques have been applied to many oilseed crops to obtain pure lines. This study highlights some salient features of producing dihaploids using irradiated pollen grains and their maintenance.
AtıfScopus1OpenAlex2TR Dizin1İncele - BildiriAçık Erişim2023Yolov5 Based Fault Detection Approach in Railway Components
Yilmazer, Merve; Karakose, Mehmet
For safe transportation on the railway, the faults occurring in its components must be detected and repaired. Recently, fault detection methods have been developed on railway visual data using methods such as image processing, machine learning and deep learning. Especially since deep learning-based algorithms have a self-learning structure, the data used in model training and testing significantly affect the performance of the model. In the proposed method within the scope of this study, railway visual data were obtained using autonomous drone. YOLOv5 deep neural network is trained to detect faults that may occur in various components such as rail, fastener, sleeper and ballast in the railway. In order to increase the efficiency of the model, images obtained under different lighting conditions were included in the data set. In addition, by using the OpenCV library, the video stabilization process and the vibrations that occur during data acquisition in the video are eliminated. Thus, with the proposed method, it has been shown that the errors due to many components in the railway can be detected with a mAP rate of 94.5%.
AtıfScopus5OpenAlex3İncele - MakaleAçık Erişim2023Scopus SJRQ3Evaluation of waste polyethylene terephalate in polyol and polyurethane production
Fırat, Tülay; Kar, Filiz
As technology advances and human population grows, we must meet our diverse needs while minimising harm to the environment. One solution is to prioritise recycling and using second-hand consumer goods. In this study, PET flakes were depolymerised by glycolysis using different molar ratios of glycol such as propylene glycol(PG), triethylene glycol(TEG) and polyethylene glycol(PEG 400) in the presence of two different catalysts: zinc acetate- zinc sulphate. As a result, glycated products (polyols-PO) were obtained. The obtained polyols were then used to synthesise polyurethane films (PU) via acetone process. The thermal and chemical characterisations of the polyurethane films (PU) were analysed. In similar studies, zinc acetate was used as a transesterification catalyst for the glycolysis process. In this study, the same process was carried out using zinc sulphate and zinc acetate. Zinc sulphate was found to be a cheaper and eco-friendlier catalyst alternative to zinc acetate for the glycolysis process.
AtıfOpenAlex1İncele - MakaleAçık Erişim2023Scopus SJRQ4COMPARATIVE ANALYSIS OF EMBROIDERY AND SCREEN-PRINTING TECHNIQUES FOR TEXTILE-BASED FREQUENCY SELECTIVE SURFACES; [TEKSTİL TEMELLİ FREKANS SEÇİCİ YÜZEYLER İÇİN NAKIŞ VE SERİGRAFİ TEKNİKLERİNİN KARŞILAŞTIRMALI ANALİZİ]
Üner, İbrahim; Can, Sultan; Gürcüm, Banu Hatice; Yilmaz, A. Egemen; Aksoy, Ertuğrul
Frequency Selective Surface (FSS) is a specialized structure used in the field of electromagnetic waves and radio frequency (RF) engineering. It is designed to exhibit selective transmission or reflection properties based on the frequency of the incident electromagnetic waves. This article describes the design, construction, and analysis of a textile-based band-stop frequency selective surface for use in the highly EM-polluted GSM, Wi-Fi, LTE, and WiMAX bands. A full-wave EM solver called CST Microwave Studio was used to develop and simulate the unit cell of the proposed FSS at the relevant frequency. In this study, embroidered and screen-printed textile based FSSs were designed. According to the results of this study, it was demonstrated that both embroidery and screen printing FSSs exhibit resonance at a frequency of 3.5 GHz. The screen printing method yielded the best results in terms of resonance frequency sensitivity, while the embroidery method showed a resonance frequency shift. It was observed that the stitch directions and density are important parameters in the embroidery method. Gaps between the embroidery paths in the production of embroidered FSSs resulted in differences from simulations due to the disruption of the structural integrity of the unit cell. Consequently, textile-based FSSs offer advantages over traditional FSSs. This study highlights the potential of textile FSSs as an effective means of reducing electromagnetic pollution, and suggests that further improvements in the design and production processes of textile FSSs can be made.
AtıfScopus2OpenAlex4İncele - MakaleAçık Erişim2023Deterioration analysis of historical village house structure in Mersin Kanlıdivane archaeological area by UAV method
Karataş, Lale; Dal, Murat
The village house located in the Mersin Kanlıdivane archaeological site is one of the oldest settlements in the ruins, built in the second century. The house is mainly built of a yellowish beige limestone. This stone, which is the main material of the building, shows many deterioration patterns today. The aim of the study is to determine the dominant deterioration pattern of the stones in the village house structure in the Mersin Kanlıdivane archaeological site and to investigate the source of the deterioration. In order to investigate the deterioration patterns in the structure, the images obtained by UAV photogrammetry were interpreted and the types of deterioration were mapped. In the study, it is seen that even the types of material problems based on the smallest detail can be determined based on virtual visual inspection, thanks to UAV photogrammetry, without observing the structure in situ with UAV photogrammetry. The findings obtained in the study shows that the color change and surface loss deterioration on the stone surfaces has reached advanced levels as a result of the structure's exposure to the strong climate-induced sun and water effects for centuries. The results of the study show that the main damage observed on the stone surface of the structure is caused by the erosion by the effect of water. Restoration methods should be tried to stabilize the deterioration and replace the most degraded stones. It is recommended to use water-repellent surface coatings to protect the natural stone, especially against the intense water effect in the building.
AtıfScopus3OpenAlex3İncele - MakaleAçık Erişim2023Scopus SJRQ3Optimization of shape factor by the response surface method, and the effect on sphalerite flotation recovery
Uysal, T.
Various morphological parameters that affect the flotation recovery of sphalerite were modelled and optimized using the response surface method (RSM). The effects of roughness value, shape factor, and collector concentration were investigated using the central composite full design method. The results were evaluated by analysis of variance. The optimum roughening time was found to be 25 minutes, the optimum roughness value was 2.9071 μm, and the optimum collector concentration was 0.001 M. Using these values, a flotation recovery of 98.01% was obtained. Similarly, in shape factor studies, the optimum grinding time was 15 seconds, the optimum roundness value 0.7421, and the optimum collector concentration 0.0009 M, which resulted in a flotation recovery of 94.30%. The average error between the optimization results and the experimental results was estimated to be less than 6%, and the R2 values were greater than 90%. The study shows that RSM can be effectively applied in finding the economic optimum condition for obtaining maximum flotation recovery with minimum reagent consumption.
AtıfScopus2WoS2OpenAlex2İncele - MakaleAçık Erişim2023Scopus SJRQ1Numerical simulation for peristalsis of Quemada fluid: A dynamic mesh approach
Ali, Shahbaz; Nadeem, Sohail; Akkurt, Nevzat; Ali Ghazwani, Hassan; Eldin, Sayed M.
Introduction: Flow dynamics due to the peristaltic pumping has been the topic of great interest for the researchers. But numerical and analytical analyses for the peristaltic motion are limited where flow domain is deformed real-time. Research on peristalsis has a limitation where theoretical aspects of walls motion are considered, neglecting the real time deformation of the walls. Objectives: This paper aims to propose a more reliable and accurate numerical methodology for peristaltic motions to address the above-mentioned challenge. Stream traces, velocities, and pressure drops along the tube is to be visualized more accurately. Methods: In present study a finite volume based dynamic mesh motion method is adopted to analyze the peristaltic motion of a non-Newtonian Quemada fluid in an axisymmetric channel. The walls and interior domain of the channel is dynamically deformed for a sinusoidal wave traveling on boundary. Results: Simulation of unsteady flow behavior for time t=0s to 2s and amplitude ratio Φ=0.2,0.4,and0.6. predicts fluid trapping phenomenon. Rotation of fluid particles is more prominent for higher amplitude ratios. Pressure gradient increases with increasing amplitude ratios. Conclusion: A novel dynamic mesh method is proposed for peristaltic pumping. It provides more accurate and more physical results for stream traces; pressure drops and velocities along the tube. A limited case of the study validates the theoretical and analytical results already presented in literature; hence the method is reliable.
AtıfScopus10OpenAlex12İncele - MakaleAçık Erişim2023Scopus SJRQ1Evaluation of pea/rice and amylopectin/chromium as an alternative protein source to improve muscle protein synthesis in rats
Ozdemir, Oguzhan; Erten, Fusun; Er, Besir; Orhan, Cemal; Komorowski, James R.; Sylla, Sarah; Perez Ojalvo, Sara; Sahin, Kazim
Background: A preclinical study reported that the combination of an amylopectin/chromium complex (ACr) of branched-chain amino acids (BCAA) significantly enhanced muscle protein synthesis (MPS). This study was conducted to determine the effects of the addition of ACr complex to a pea/rice (PR) protein on MPS, insulin, muslin levels, and the mTOR pathway in exercised rats. Methods: Twenty-four rats were divided into three groups: (i) exercise (Ex); (ii) Ex + PR 1:1 blend (0.465 g/kg BW); (iii) Ex + PR + ACr (0.155 g/kg BW). On the day of single-dose administration, after the animals were exercised at 26/m/min for 2 h, the supplement was given by oral gavage. The rats were injected with a bolus dose (250 mg/kg BW, 25 g/L) of deuterium-labeled phenylalanine to determine the protein fractional synthesis rate (FSR) one h after consuming the study product. Results: The combination of PR and ACr enhanced MPS by 42.55% compared to the Ex group, while Ex + PR alone increased MPS by 30.2% over the Ex group (p < 0.0001) in exercised rats. Ex + PR plus ACr significantly enhanced phosphorylation of mTOR and S6K1 (p < 0.0001), and 4E-BP1 (p < 0.001) compared to the Ex (p < 0.0001). PR to ACr also significantly increased insulin and musclin levels (p < 0.0001) in exercised rats. Additionally, compared to Ex + PR alone, Ex + PR + ACr enhanced mTOR (p < 0.0001) and S6K1 (p < 0.0001) levels. Conclusion: These data suggested that PR + ACr may provide an alternative to animal proteins for remodeling and repairing muscle by stimulating MPS and mTOR signaling pathways in post-exercised rats. More preclinical and clinical human studies on combining pea/rice and amylopectin/chromium complex are required.
AtıfScopus4OpenAlex4İncele - MakaleAçık Erişim2023Determination of Rutting Resistance of SBS and Warm Asphalt Additive Binders by the MSCR Test
Akpolat, Mustafa
The MasterLife PAV110 Warm Mix Asphalt (WMA) additive’s rutting resistance in pure and Styrene-Butadiene-Styrene (SBS)-modified binders was examined using MSCR testing. Multiple Stress Creep Recovery (MSCR) tests were conducted on seven binders. The study’s findings indicated that the incorporation of WMA resulted in an increase in the Jnr values of both pure binders and binders modified with SBS at stress levels of 0.1 and 3.2 kPa. This finding implies that the occurrence of rutting will be negatively impacted. On the other hand, the performance level categorization showed that WMA additives had no impact on the performance levels of pure and SBS-modified binders. Since the Jnr and average percentage Recovery (R) values at 3.2 kPa, 1%, and 1.5% PAV110 additives exhibited similar properties, it was determined that the optimum usage rate in terms of cost was 1%.
AtıfScopus2OpenAlex2İncele - MakaleAçık Erişim2023Scopus SJRQ2Unraveling the chemical profile, antioxidant, enzyme inhibitory, cytotoxic potential of different extracts from Astragalus caraganae
Kurt-Celep, İnci; Zengin, Gokhan; Uba, Abdullahi I.; Caprioli, Giovanni; Mustafa, Ahmed M.; Angeloni, Simone; Cakilcioglu, Ugur; Guler, Osman; Kaplan, Alevcan; Sharmeen, Jugreet
Six extracts (water, ethanol, ethanol-water, ethyl acetate, dichloromethane, and n-hexane) of Astragalus caraganae were studied for their biological activities and bioactive contents. Based on high-performance liquid chromatography-mass spectrometry (HPLC-MS), the ethanol-water extract yielded the highest total bioactive content (4242.90 µg g−1), followed by the ethanol and water extracts (3721.24 and 3661.37 µg g−1, respectively), while the least total bioactive content was yielded by the hexane extract, followed by the dichloromethane and ethyl acetate extracts (47.44, 274.68, and 688.89 µg g−1, respectively). Rutin, p-coumaric, chlorogenic, isoquercitrin, and delphindin-3,5-diglucoside were among the major components. Unlike the dichloromethane extracts, all the other extracts showed radical scavenging ability in the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay (8.73–52.11 mg Trolox equivalent [TE]/g), while all extracts displayed scavenging property in the 2,2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging assay (16.18–282.74 mg TE/g). The extracts showed antiacetylcholinesterase (1.27–2.73 mg galantamine equivalent [GALAE]/g), antibutyrylcholinesterase (0.20–5.57 mg GALAE/g) and antityrosinase (9.37–63.56 mg kojic acid equivalent [KAE]/g) effects. The molecular mechanism of the H2O2-induced oxidative stress pathway was aimed to be elucidated by applying ethanol, ethanol/water and water extracts at 200 µg/mL concentration to human dermal cells (HDFs). A. caraganae in HDF cells had neither a cytotoxic nor genotoxic effect but could have a cytostatic effect in increasing concentrations. The findings have allowed a better insight into the pharmacological potential of the plant, with respect to their chemical entities and bioactive contents, as well as extraction solvents and their polarity.
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