Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Sançar, Taylan(3)
- Çimen, Okay(3)
- Simonetti, Antonio(2)
- Ak, Tuba Parlak(1)
- Aksoy, Murat Ersen(1)
- Akyüz, Hüsnü Serdar(1)
- Akçar, Naki(1)
- Altin, Mehmet Uğur(1)
- Basmenji, Mehran(1)
- Baykalir, Burcu Gül(1)
- Başak, Neşe(1)
- Boulton, Sarah J.(1)
- Can, Erkan(1)
- Cemalgil, Selim(1)
- Corcoran, Loretta(1)
- Demırcan, Huriye(1)
- Dikbaş, Aynur(1)
- Er, Beşir(1)
- Erten, Füsun(1)
- Ferry, Matthieu(1)
- Friedrich, Anke M.(1)
- Göncüoğlu, M. Cemal(1)
- Gönen, Tahir(1)
- Görmüş, Muhittin(1)
- Gücer, Mehmet Ali(1)
- Güllüoglu, Hakan(1)
- Ipek, Yeliz(1)
- Ivy-Ochs, Susan(1)
- Kadioğlu, Yusuf Kağan(1)
- Karaoğlan, Fatih(1)
- Korunur, Murat(1)
- Kuebler, Corinne(1)
- Meghraoui, Mustapha(1)
- Morde, Abhijeet A.(1)
- Orhan, Cemal(1)
- Padigaru, Muralidhara(1)
- Sayit, Kaan(1)
- Seven, Ismail(1)
- Seven, Pinar Tatli(1)
- Simonetti, Stefanie S.(1)
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ2Effects of fenugreek and shatavari on vasomotor and hormonal balance in ovariectomized rats
Erten, Füsun; Er, Beşir; Orhan, Cemal; Morde, Abhijeet A.; Padigaru, Muralidhara; Şahin, Kazim
Trigonella foenum-graecum L. (fenugreek, TFG) and Asparagus racemosus Willd. (shatavari, AR) have been extensively used in Ayurvedic, Unani, and traditional folk medicine to support women’s health. TFG seeds are traditionally employed as galactagogues and hormonal modulators, while AR roots are valued as rejuvenating tonics with phytoestrogenic activity, prescribed for menopausal complaints and reproductive well-being. Both plants also exhibit antioxidant and hepatoprotective effects, suggesting their potential as safe, nonhormonal alternatives to conventional hormone replacement therapy. This study investigated the dose-dependent effects of TFG and AR, administered individually or in combination, on vasomotor symptoms, hormonal balance, oxidative stress, and neuroendocrine markers in an ovariectomized (OVX) rat model of menopause. Adult female rats underwent bilateral ovariectomy and were randomized into eight groups: Control, OVX, OVX+TFG (30 and 60 mg/kg), OVX+AR (30 and 60 mg/kg), and OVX+TFG/AR combinations. Treatments were administered orally for 8 days. Tail, core, and skin temperatures were recorded to assess thermoregulation, while blood and tissue samples were analyzed for hormone levels, oxidative stress, and molecular markers. OVX rats showed classical menopausal alterations, including increased follicle-stimulating hormone, luteinizing hormone, cortisol, and malondialdehyde, and decreased 17β-estradiol, progesterone, dopamine, and antioxidant enzymes, along with dysregulated neuroendocrine markers. All treatments partially reversed these changes, while the high-dose combination (TFG/AR 60 mg/kg each) demonstrated the most pronounced effects, normalizing hormone levels, reducing hot-flash-like temperature fluctuations, restoring antioxidant activity, downregulating neuroendocrine markers (c-FOS, GnRH, Kisspeptin, NKB, and TRPV1) expression, and elevating brain-derived neurotrophic factor levels (p < 0.05). High-dose combined supplementation of TFG and AR effectively alleviates vasomotor disturbances, restores hormonal and oxidative balance, and modulates neuroendocrine pathways in OVX rats. These findings validate their traditional use and highlight their potential as safe phytoestrogen-based, nonhormonal alternatives for the management of menopausal symptoms, warranting further clinical evaluation.
- MakaleAçık Erişim2026Scopus SJRQ4Comparison of the Performance of Machine Learning Methods with Intuitionistic Fuzzy Decision Making for Effective Fake News Detection
Tuğrul, Feride
In this paper, the success of machine learning models applied to two datasets consisting of fake news was examined. The performance of these methods was measured using Accuracy, Precision, Recall, and F1-Score. Evaluation metrics for all models were calculated using TF-IDF and N-gram TF-IDF for Dataset 1 and Dataset 2, respectively. In continuation of the study, a decision-making mechanism was created to measure the success of machine learning methods. The success of these models was compared by creating a decision-making mechanism using intuitionistic fuzzy sets. The PROMETHEE method was used here. In the first stage of the study, the dataset samples evaluated were expressed using classical sets, while in the second stage, the success of the models according to the metrics was expressed using intuitionistic fuzzy values. This was to minimize the uncertainty in the model success results. The results obtained in the first stage of the study were evaluated in the second stage using a decision-making mechanism. In this mechanism, machine learning models represent the alternatives, while classification metrics represent the criteria. When evaluating machine learning models, experts provide subjective opinions based on each classification metric to determine the successful model.
- MakaleAçık Erişim2025Scopus SJRQ2Geochronological and isotopic data from the adakitic Dodurga Pluton (Central Pontides, N Türkiye): new insights for the geodynamic evolution of the northern Neotethys
Çimen, Okay; Gücer, Mehmet Ali; Simonetti, Antonio; Karaoğlan, Fatih
The Dodurga Pluton is located within the Central Pontides (northern Türkiye), has a SW–NE elongation, and consists of granodiorite and dacite porphyry. Previous studies have suggested that this pluton is Triassic in age, and its whole-rock geochemical systematics is consistent with that from adakitic magmatic occurrences rather than the classic arc granitoid suite. This study reports for the first time in situ/whole-rock radiogenic isotopic (Sr, Nd, and Pb) and mica/amphibole Ar–Ar age data to evaluate better its petrogenetic/geodynamic evolution and the chemical nature of mantle source(s). Unlike previous data, combined new in situ zircon U–Pb yield Late Cretaceous crystallization ages of 84.2 ± 0.9 Ma and 86.9 ± 0.9 Ma, and the Ar–Ar age data along with apatite fission track measurements suggest magma cooling extending to 82.3 ± 0.4 Ma and 85.4 ± 0.4 Ma, respectively. The apatite fission track (AFT) dating results also reveal that this pluton was buried at a depth of 2.5–3 km following a fast-cooling period during the Late Cretaceous and cooled/exhumed over ~2 km during the Middle–Late Miocene (15–10 Ma) in a slow cooling phase. The overall data reported here suggest that the Dodurga Pluton represents melts derived from an enriched/metasomatized mantle source that interacted with lower crustal mafic rocks in an active continental margin as a result of northward subduction of the northern branch of the Neotethys Ocean.
- MakaleAçık Erişim2023Scopus SJRQ4Using the Taguchi Method to Optimize the Compressive Strength of Concrete in Different Aggregates Typology; [Farklı Tipolojideki Doğal Agregalı Betonların Basınç Dayanımını Optimize Etmede Taguchi Metodunun Kullanımı]
Gönen, Tahir; Cemalgil, Selim
Concrete quality is affected by many factors such as mixing ratios, material quality, transporting, placing and curing. One of the crucial factors that changes the compressive strength of concrete is aggregate which makes up 75% of concrete during concrete production. Properties of aggregate are more unstable than other materials depending on various reasons. Granulometry, moisture or organic substance amount of the aggregates which have same origin may differ within time. This study investigates physical and mechanical properties of crushed limestone and crushed river aggregates. It is on optimum design of concrete with crushed limestone and crushed river aggregates. At first, physical and mechanical properties of the aggregates are measured, then Taguchi method is applied. Test variables are water-to-binder ratio, cement dosage, river sand ratio to limestone and air entrained agent. L16 orthogonal array as an experimental design method is applied to determine the optimum concrete design in terms of compressive strength and flexural strength. Furthermore, contribution of variables on compressive and flexure strength is determined statically by using ANOVA method. Among the 4 different aggregate ratios evaluated in the study, the best performance is from the combination of 70% stream and 30% limestone. The weakest performance is from the series that do not contain any stream material.
AtıfScopus2
İncele - MakaleAçık Erişim2023Scopus SJRQ2Paleoseismology of the Ganos segment; the western extend of the North Anatolian Fault (Turkey)
Aksoy, Murat Ersen; Meghraoui, Mustapha; Ferry, Matthieu; Çakir, Ziyadin; Uçarkuş, Gülsen; Sançar, Taylan; Altin, Mehmet Uğur
The Ganos fault that ruptured on 9 August 1912 (Mw: 7.4) is the westernmost inland segment of the North Anatolian fault (NAF). Here, the Ganos fault is bounded at its two tips with offshore faults segments, in the Sea of Marmara to the east and the Gulf of Saros to the west in the North Aegean Trough. Therefore, the paleoseismology of the 45-km-long inland fault is of importance to the seismic hazard analysis related to offshore active faults and in particular for the seismic gap in the Marmara Region. Earlier studies have established an earthquake chronology for the western and eastern inland tips of the Ganos fault. Here, we extend the paleoseismic studies toward the central segment. Three trenches at Yörgüç have revealed evidence for two faulting events, possibly post-1669 CE ±30 years, which can be correlated to the 1659 or 1766, and the 1912 historical earthquakes. At Yeniköy, we determined an offset of 46 ± 1 m and 47 ± 1 m on a stream channel and a ridge-crest, respectively. In two trenches we determined two faulting events for the last 1000 years and seven events for the last 3500 years. In trench T5, the base of the displaced stream channel provides a calibrated date of 829–591 BCE. Using the 46 ± 1 m right-lateral displacement, we calculate a slip rate of 16.9 ± 0.7 mm/year for the last 2732 ± 119 years. A combined analysis with earlier paleoseismic studies on the Ganos fault suggests that the historical earthquakes of 1912, 1766b or 1659, 1354 or 1343a, and 1063 ruptured the entire inland fault section. In such a case, the recurrence interval for this section of the NAF corresponds to 283 ± 81 years. Combining earlier estimations, we suggest an average slip rate of 17.1 ± 0.9 mm/year for the last 2700 years and observe a characteristic slip behavior of 4.5 to 5 m per event for this section of the North Anatolian plate boundary fault.
AtıfScopus1OpenAlex2
İncele - MakaleAçık Erişim2023Scopus SJRQ2Internal deformation of continental blocks within converging plates: insights from the Ovacık Fault (Anatolia, Türkiye)
Zabci, Cengiz; Sançar, Taylan; Tikhomirov, Dmitry; Ivy-Ochs, Susan; Vockenhuber, Christof; Friedrich, Anke M.; Yazici, Müge; Akçar, Naki
The active tectonics of Anatolia is mostly characterized by its westward motion with respect to Eurasia between the Hellenic subduction in the west and Arabia-Eurasia continental collision in the east. Although most of the deformation is suggested to be confined along Anatolia’s boundary elements, viz. the North and East Anatolian shear zones, recent studies indicate a higher magnitude of internal strain accumulation, especially along the parallel/subparallel strike-slip faults of its central province. We present the first morphochronology-based slip rate estimate for one of these strike-slip structures, the Ovacık Fault, by using cosmogenic36Cl dating of offset fluvial deposits. At the Köseler Site (39.3643°N, 39.1688°E), two faulted risers, bounding the alluvial fan with its subplanar surface (NF1/NF1’) and the inset terrace tread (NF1/T2), are offset 19–24 and 15–22 m, respectively. The scattered surface ages and variability of 36 Cl concentrations in depth profiles suggest strong evidence for inheritance in alluvial fan and terrace deposits; thus, we used modelled depth-profile ages for both surfaces. The modelled ages 8–10 ka for NF1 and 6–8 ka for T2 yield slip-rate estimates 2.4 +0.5/–0.4 mm/a and 2.8 +0.7/–0.7 mm/a, respectively, for the upper-tread reconstruction of the NF1/NF1’and the lower-tread reconstruction of the NF1/T2. Our results together with previous slip-rate estimates for other structures show a significant internal deformation for Anatolia, especially along its subparallel strike-slip faults. These secondary faults slice Anatolia into several pieces giving rise to the formation of the Malatya-Erzincan, Cappadocian, and Central Anatolian slices, where the geometry is strongly controlled by the distribution of the Tethyan accretionary complexes.
AtıfScopus3OpenAlex3TR Dizin1İncele - MakaleAçık Erişim2021Scopus SJRQ2Tectonic geomorphology of the yatağan fault (Muğla, sw turkey): Implications for quantifying vertical slip rates along active normal faults
Basmenji, Mehran; Sançar, Taylan; Dikbaş, Aynur; Boulton, Sarah J.; Akyüz, Hüsnü Serdar
South Western Anatolia is dominated by E-W and NW-SE trending active faults. The dip-slip Yatağan Fault is one of these active structures that trends in a NW direction for ~30 km. To assess the relative tectonic activity of the Yatağan Fault, two geomorphic segments were defined along the fault: the FS-1 (northern segment) and the FS-2 (southern segment). The vertical slip rate pattern of the fault was analyzed using steepness indexes, chi (χ) plots, and log-log slope area graphs. Results of the analyses indicate that the steepness of the streams draining the footwall reveal increasingly higher values downstream along the fault. All of the main basins contain at least one slope-break knickpoint associated with tectonic uplift. Facet morphology-based investigations using empirical methods along faceted spurs of the Yatağan Fault indicate vertical slip rates of 0.16 ± 0.05 mm/year and 0.3 ± 0.05 mm/year for the FS-1 and the FS-2, according to relationship of facet slope angle (Rsa ). Additionally, using the facet basal height relationship (Rbh ) we calculated slip rates of 0.24 mm/year and 0.36 mm/year for the FS-1 and the FS-2 segments, respectively. Mountain front sinuosity analysis yields values of 1.34 and 1.2, while the ratio of valley-floor width to valley height gives values of 0.64 and 0.24 for the FS-1 and the FS-2 respectively, indicating typical active mountain front where the uplift rates are ≥ 0.5 mm/year. Hypsometric analysis suggest a transition from mature to older stage for catchments along the Yatağan Fault. Comprehensive interpretation of the results from morphometric analysis, vertical slip rate calculations, and data based on field observations suggest preponderance of tectonic activity over erosional process along the Yatağan Fault. Our analyses reveal that the rate of the tectonic activity gradually increases from the FS-1 to the FS-2 along the fault.
AtıfScopus4İncele - MakaleAçık Erişim2020Scopus SJRQ33d surface modeling of late pleistocene glaciers in the Munzur mountains (Eastern Turkey) and its paleoclimatic implications
Çilğin, Zeynel
Located in the Eastern Anatolian Region in Turkey, the Munzur Mountains (Munzurs; 3463 m above sea level) are one of the most important glacial landscapes in Turkey, with evidence for extensive glaciations in the past and small-scale glaciation at present. As Turkey’s second-largest glaciated region, these mountains include various glacial landforms, primarily glacial valleys, hanging valleys, cirques, and moraines. However, only limited data are available on the extent and chronology of former glaciations in the Munzur Mountains. This study produced data on the extent of paleoglaciers, calculated their equilibrium line altitudes (ELAs), revealed paleoclimate conditions, and modeled paleo temperatures during maximum ice extent using numerically derived reconstruction methods (GlaRe and ELA calculation tools) based on geomorphic evidence. The major glacial landforms were first mapped in detail before the reconstruction. Six hundred and eighty cirques and 30 glaciated valleys were identified. Paleoglaciers did not override the entire mountains, however, valley glaciers converged where topographic conditions were suitable.The maximum extent of glaciation covered an area of ca. 600 km2. The largest glacier was ca. 19 km in length. Moreover, 15 of the valley glaciers were over 10 km in length. Their average thickness was 75 m, and the maximum glacial thickness, in the Eastern Munzurs, was found to be ca. 300 m. The total volume of ice reached ca. 45 km3. The paleoglaciers reached as low as 1350 m above sea level. The average ELA was calculated approximately 2600 m above sea level, indicating an equilibrium line altitude depression of 1000–1100 m. The paleotemperatures, estimated based on different scenarios at the time of the maximum extent of Munzur glaciers, were 8–10 °C lower than today. The mountains experienced an increase in precipitation through this period with respect to the current precipitation scheme.
AtıfScopus9WoS10OpenAlex16TR Dizin8İncele - MakaleAçık Erişim2020Scopus SJRQ3Effect of surfactant types on particle size and morphology of flame-retardant zinc borate powder
Ipek, Yeliz
Zinc borate is a boron-containing chemical material that is used to increase the flame retardancy of polymeric materials, dyes, cables, fabrics, carpets, and the internal parts of automobiles and planes. Commercially used zinc borate, which has the formula of 2ZnO·3B2O3·7H2O, has a particle size between 10 and 20 μm. However, recent studies have shown that nanosized flame retardants have more superior flame retardancy and less negative effects on mechanical properties than microsized flame retardants. Nanosized flame retardants disperse more homogeneously and even low quantities are sufficient to provide high flame resistance. In this study, nano zinc borate powder was synthesized by a wet chemical method and the effects of nonionic, anionic, and cationic surfactants on the particle size and morphology of the zinc borate particles were investigated. Chemical purity and physical structures of the synthesized zinc borate powder were analyzed by XRD, FTIR, TG-DTA, TEM, and Zetasizer. The analysis results showed that the zinc borate powder had a chemical formula of 2ZnO·3B2O3·7H2O. TEM and Zetasizer results indicated that the nano zinc borate powder, which had nanoscale particle size distribution with needle- and flake-like structures, was synthesized using nonionic, anionic, and cationic surfactants.
AtıfScopus17WoS15OpenAlex18TR Dizin3İncele - MakaleAçık Erişim2020Scopus SJRQ3Geochemical, stable (O, c, and b) and radiogenic (sr, nd, pb) isotopic data from the eskişehir-kızılcaören (nw-anatolia) and the malatya-kuluncak (e-central anatolia) f-ree-th deposits, Turkey: Implications for nature of carbonate-hosted mineralization
Çimen, Okay; Corcoran, Loretta; Kuebler, Corinne; Simonetti, Stefanie S.; Simonetti, Antonio
In Turkey, the largest fluorine (F)-rare earth element (REE)-thorium (Th) deposits are located within the Eskişehir-Kızılcaören (north-western Anatolia) and the Malatya-Kuluncak (east-central Anatolia) regions, and these are associated with Oligocene extensional alkaline volcanic and Late Cretecaous-Early Paleocene postcollisional intrusive rocks, respectively. In the Kızılcaören region, the basement units include the Triassic Karakaya Complex and the Late Cretaceous oceanic units (Neotethyan suture) that are cut and overlain by phonolite and carbonatite intrusions and lava flows. In the Kuluncak region, the plutonic rocks are mainly composed of syenite, quartz syenite, and rare monzonite, and these cut the late-Cretaceous Karapınar limestone, which hosts the F-REE-Th mineralization in contact zones. A carbonatite sample from the Kızılcaören region displays both a total rare earth element (TREE) concentration (4795 ppm) and δ11B (–6.83‰) isotope composition consistent with mantle-derived carbonatite; whereas it is characterized by heavier δ13C (+1.43‰) and δ18O (+20.23‰) isotope signatures compared to those for carbonatites worldwide. In contrast, the carbonates which host the F-REE-Th mineralization in the Kuluncak region are characterized by lower TREE concentrations (5.13 to 55.88 ppm), and heavier δ13C (–0.14 to –0.75‰), δ18O (+27.36 to +30.61‰), and δ11B (+5.38 to +6.89‰) isotope ratios compared to mantle-derived carbonatites. Moreover, the combined initial87Sr/86Sr (0.70584 to 0.70759) and143Nd/144Nd (0.512238 to 0.512571) isotope ratios for samples investigated here are distinct and much more radiogenic compared to those for carbonatites worldwide, and therefore indicate significant crustal input and/or hydrothermal metasomatic-related alteration. Overall, stable and radiogenic isotope data suggest that the host carbonate rocks for the F-REE-Th mineralization in both the Kızılcaören and the Kuluncak regions consist of hydrothermally metasomatized carbonatite and limestone, respectively. The mineralization in the Kızılcaören region may potentially be related to carbonatite magmatism, whereas the mineralization in the Kuluncak region, which most likely formed through interactions between the plutonic rocks and surrounding limestone at contact metamorphism zone, involved hydrothermal/magmatic fluids associated with extensive postcollisional magmatism.
AtıfScopus15WoS14OpenAlex18İncele - MakaleAçık Erişim2019Scopus SJRQ2Microborings as indication of cryptic life modes in the foraminifer Orbitoides: Maastrichtian sediments of the Haymana and Nallihan districts (Ankara, Turkey)
Görmüş, Muhittin; Demırcan, Huriye; Kadioğlu, Yusuf Kağan; Yağmurlu, Fuzuli; Us, Muhammed Sami
Widespread Maastrichtian siliciclastics and carbonates cropping out in the Haymana (S Ankara) and Nallihan (NW Ankara) districts in the northwest and central Anatolia basins include rich Orbitoides occurrences. Microborings in the Orbitoides tests are interesting to notify. In this study, the details of their morphologic structures were investigated. Microborings were analyzed in more than 650 equatorial thin sections of the Orbitoides tests and 100 hard rock thin sections. The abundance of microborings increases in the siliciclastics towards the Cretaceous/Palaeogene boundary (K/Pg). They were identified as Maeandropolydora osmaneliensis Nielsen and Görmüs, Maeandropolydora isp. Curvichnus semorbis Nielsen, Oichnus simplex Bromley, Oichnus isp. Maeandropolydora osmaneliensis Nielsen and Görmüs. Maeandropolydora isp., semicircular to circular microborings of Curvichnus semorbis Nielsen and Oichnus simplex Bromley are related to parasitic life modes. Irregular wider unidentified microborings are hermit type life mode tunnels. Abundance of the microborings might be related to shallower siliciclastic environmental conditions such as feeding and suitable Eh-pH, test shape, and easy entrance to the test for parasites. Smaller benthic foraminifera are seen in both microspheric and megalospheric Orbitoides tests as parasites. In conclusion, occurrences of microborings and encrustations are associated with parasitism by appearances of Maeandropolydora osmaneliensis Nielsen and Görmüs, Curvichnus semorbis Nielsen and Oichnus simplex Bromley and commensally attachment by microalgae.
AtıfScopus10OpenAlex8İncele - MakaleAçık Erişim2019Scopus SJRQ3Anesthetic and sedative efficacy of peppermint (Mentha piperita) and lavender (Lavandula angustifolia) essential oils in blue dolphin cichlid (Cyrtocara moorii)
Can, Erkan; Sümer, Esma
The use of different essential oils (Eos), which are considered as a good alternative to synthetic materials, is increasing day by day in fish species. Nevertheless, studies on the anesthetic effect of peppermint Eo (Mentha piperita; MPEo) and lavender Eo (Lavandula angustifolia; LAEo) are scarce. In the present study, the effective concentrations of three anesthetic materials (MPEo, LAEo, and MS-222) were previously determined in the concentrations range of 100–400 ppm in Cyrtocara moorii juveniles (4.92 ± 1.03 g and 7.13 ± 1.22 cm) with the criteria of appropriate induction time (AIt) and ready recovery time (RRt) (Trial 1). Afterwards, four different groups were established at three different sedative concentrations (10, 20, and 30 ppm and a control group without anesthetic additive) for transporting (Trial 2). The study concluded that MPEo and LAEo can be used as anesthetic and sedative agents in tropical fish species safely. The use of 100 µL L–1 (183.5 s AIt and 227.8 s RRt) and 300 µL L–1 (109.2 s AIt and 420.0 s RRt) MPEo and LAEo, respectively, was sufficient for deep anesthesia, whereas concentrations in the range of 10 to 30 µL L–1 are recommended for fish transport.
AtıfScopus21WoS20OpenAlex22TR Dizin3İncele - MakaleAçık Erişim2018Scopus SJRQ3The protective effects of chrysin and flunixin meglumine against excess copper in male rats
Seven, Pinar Tatli; Baykalir, Burcu Gül; Seven, Ismail; Ak, Tuba Parlak; Başak, Neşe; Güllüoglu, Hakan
Thirty-six Sprague Dawley male rats were housed in individual cages and randomly divided into six groups: Control, copper sulfate (Cu; 500 ppm body weight (BW)/day), flunixin meglumine (FM; 2.2 ppm BW/day), chrysin (chrysin; 50 ppm BW/day), copper sulfate + FM (Cu + FM; 500 ppm BW/day of copper sulfate and 2.2 ppm BW/day of FM), and copper sulfate + chrysin (Cu + Chrysin; 500 ppm BW/day of copper sulfate and 50 ppm BW/day of chrysin). Feed intake (FI) in the Cu + Chrysin group significantly increased in comparison with that of the Cu group (P < 0.01). Cu excess significantly increased malondialdehyde, indicating oxidative stress. Chrysin and FM administration significantly decreased malondialdehyde levels and increased the superoxide dismutase and catalase activities in the liver and kidney tissues (P < 0.001). Serum TNF-α levels were significantly lower in the Cu + FM and Cu + Chrysin groups in comparison to the Cu group (P < 0.001). It was seen that FM and chrysin treatments alleviated degeneration, necrosis, and apoptosis in the liver and kidney tissues of the Cu-treated rats. Chrysin appeared to ameliorate the adverse effects on FI and liver and kidney tissues by scavenging where the free radicals are located and increasing the activity of antioxidants.
AtıfScopus8WoS7OpenAlex9TR Dizin2İncele - MakaleYalnız künye2017Scopus SJRQ4Second law of gravitational thermodynamics in the locally rotationally symmetric Bianchi type-II universe
Korunur, Murat
In this work, under the assumption that the universe is locally rotationally symmetric (LRS) Bianchi type-II and filled with anisotropic dark uid (dark energy and dark radiation), we investigate whether the generalized second law of thermodynamics (GSLT) is still valid. We also consider another important condition for LRS Bianchi type-II spacetimes whereby the model expansion is proportional to the shear, which leads to B = An (where n is a constant and A and B are the metric potentials). Based on this, we derive a general circumstance for the GSLT and find that its validity depends on the anisotropies of both the dark uid and the metric potentials. We conclude that the GSLT still holds at all times even if these two anisotropic conditions are removed from the results.
AtıfScopus3WoS3OpenAlex3İncele - MakaleAçık Erişim2016Scopus SJRQ1Geochemistry of the metavolcanic rocks from the Çangaldağ complex in the central pontides: Implications for the middle jurassic arc-back-arc system in the neotethyan intra-pontide ocean
Çimen, Okay; Göncüoğlu, M. Cemal; Sayit, Kaan
The Cangaldağ Complex in northern central Turkey is one of the main tectonic units of the Central Pontide Structural Complex that represents the remains of the poorly known Intra-Pontide branch of the Neotethys. It comprises low-grade metamorphic rocks of intrusive, extrusive, and volcaniclastic origin displaying a wide range of felsic to mafic compositions. Petrographically the complex consists of basalts-andesites-rhyodacites and tuffs with minor amount of gabbros and diabases. On the basis of geochemistry, the Cangaldağ samples are of subalkaline character and represented by both primitive and evolved members. All rock types are variably depleted in Nb compared to LREEs, similar to the lavas from subduction-related tectonic settings. In N-MORB normalized plots, the primitive members are separated into 3 groups on the basis of levels of enrichment. The first group is highly depleted and displays characteristics of boninitic lavas. The second group is relatively enriched compared to the first group but still more depleted than N-MORB. The third group, however, is the most enriched one among the three, whose level of enrichment is around that of N-MORB. The overall geochemical features suggest that the Cangaldağ Complex has been generated with the involvement of a subductionmodified mantle source. The chemistry of the primitive members further indicates that the melts generated for the formation of the Cangaldağ Complex probably occurred in both arc and back-arc regions above an intraoceanic subduction within the Intra-Pontide branch of the Neotethys.
AtıfScopus39WoS39OpenAlex31İncele - DergiTurkish Journal of Physics
- DergiTurkish Journal of Veterinary and Animal Sciences
- DergiTurkish Journal of Chemistry
- DergiTurkish Journal of Earth Sciences
- DergiTurkish Journal of Agriculture and Forestry