Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleAçık Erişim2026Scopus SJRQ2
    Antioxidant capacity and α-glucosidase inhibitor activity of Bryonia aspera extracts and its major constituent p-coumaric acid: Phytochemical analysis, biological evaluation and computational approach

    Tuncay, Salih; Karasakal, Ömer Faruk; Açar, Mikail; Toptancı, İsra; Şenol, Halil; Çırak, Olgun; Işık, Mesut; Beydemir, Şükrü

    This study comprehensively investigated the phenolic composition, antioxidant potential, and α-glucosidase inhibitory properties of B. aspera Steven ex Ledeb. extracts using integrated in vitro and in silico approaches. LC-MS/MS analysis identified seven major phenolic compounds, caffeic acid, chlorogenic acid, galangin, gallic acid, naringenin, p-coumaric acid, and rutin, with p-coumaric acid being the most abundant (306.71 mg/kg in aerial and 155.56 mg/kg in root extracts). Both extracts exhibited strong antioxidant and α-glucosidase inhibitory activities, particularly the aerial extract (IC50 = 0.678 and 0.173 for DPPH, ABTS, respectively and 0.022 mg/mL for α-glucosidase inhibition). Molecular docking and MM-GBSA analyses supported these findings, showing that p-coumaric acid had the strongest binding to α-glucosidase (–7.783 kcal/mol, ΔG = –47.76 kcal/mol), stabilized by key interactions with Asp-62, Arg-200, His-332, and Arg-400. A 250 ns molecular dynamics simulation confirmed the stability of the complex, and in silico ADME analysis revealed good oral absorption (67%) and compliance with Lipinski’s rule. Overall, results indicate that p-coumaric acid is the primary bioactive compound contributing to the antioxidant and α-glucosidase inhibitory activity of B. aspera, with promising potential as a natural lead for α-glucosidase inhibition.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2026Scopus SJRQ2
    Oxalic Acid–MAP Synergy in Maintaining Postharvest Grape Quality and Biochemical Content

    Küçüker, Emine; Ağlar, Erdal; Sümbül, Ahmet; Demir, Selda; Özcengiz, Ceyda Kizgin; Güzel, Sedat

    This study was conducted to investigate the effects of oxalic acid (OA) and modified atmosphere packaging (MAP) applications, both alone and in combination, on the preservation of postharvest quality characteristics of grapes. All samples were stored at 4 ± 1 °C and approximately 80–85% relative humidity for 28 days. The OA + MAP treatment most effectively limited weight loss (10.49%), soluble solids content (SSC; 20.62°Bx), and decay rate (1.78%), while providing the best preservation of total phenolic content (68.25% change), antioxidant activity (53.19% change), and individual phenolic compounds at the end of the storage period. A decrease in color parameters, including L* and a* values, was observed, with OA treatment particularly prominent in preserving the red color. Principal component analysis and hierarchical heatmap analysis confirmed distinct clustering of treatments from the control, highlighting the process efficiency of packaging-based interventions. The combination of OA and MAP treatments was more effective than either treatment alone in reducing quality losses in grapes during storage. Therefore, the widespread use of OA + MAP in commercial storage and marketing processes is recommended.

    • SDG 2 · Açlığa Son
    • SDG 12 · Sorumlu Üretim ve Tüketim
  • MakaleAçık Erişim2026Scopus SJRQ1
    Pomological and Biochemical Properties of Rosehip (Rosa canina L.) Genotypes

    Ertugrul, Edanur; Aglar, Erdal; Ozturk, Burhan; Tekin, Onur; Alan, Davut; Ates, Umut

    Rosehip (Rosa canina L.) is an important wild fruit species valued for its high nutritional and functional properties, particularly its richness in vitamin C, phenolic compounds, and antioxidant activity. Despite the widespread natural distribution of rosehip in Türkiye, many local genetic resources remain insufficiently characterized, limiting their effective utilization in breeding, conservation, and cultivation programs. The present study was conducted to evaluate the morphological, pomological, and biochemical characteristics of naturally growing rosehip genotypes in the Central District of Tunceli and to identify superior genotypes with potential for future breeding and cultivation efforts. Ten rosehip genotypes collected from natural populations at altitudes ranging from 1178 to 1256 m were evaluated for fruit and seed characteristics, fruit color, soluble solids content, titratable acidity, vitamin C, phenolic compounds, flavonoids, anthocyanins, antioxidant activity, and organic acid composition. Significant differences were observed among genotypes for all examined traits. Fruit weight ranged from 1.00 to 1.81 g, soluble solids content from 45.40% to 51.90%, titratable acidity from 1.03% to 2.77%, and vitamin C content from 235.67 to 1126.30 mg/100 g. Total phenolic content, total flavonoid content, total monomeric anthocyanin content, FRAP, and DPPH antioxidant activity values also varied significantly among genotypes. Organic acid analysis revealed considerable variation, particularly in citric and malic acid contents. Principal component analysis explained 92.4% of the total variation and grouped the genotypes into two major clusters. Based on the overall evaluation, genotypes TK2, TK5, TK9, and TK10 exhibited superior performance for several desirable traits. The results demonstrate the substantial genetic diversity present in the natural rosehip populations of Tunceli and highlight their potential value for germplasm conservation, selection breeding, and sustainable cultivation programs.

    • SDG 2 · Açlığa Son
  • MakaleAçık Erişim2026Scopus SJRQ1
    Pomological and Biochemical Characterization of Autochthonous Grape Varieties Grown in Türkiye

    Karasu, Yakup; Dogan, Adnan; Aykut, Semih; Ozturk, Burhan; Aglar, Erdal

    Grapevine (Vitis vinifera L.) is an important fruit crop with considerable morphological and biochemical diversity, and autochthonous genotypes represent valuable genetic resources for breeding and conservation programs. Many local varieties remain underexplored in terms of pomological and antioxidant traits. Eighteen indigenous grape genotypes collected from Muş province (Eastern Anatolia, Türkiye) were evaluated using morphological and biochemical parameters, including berry traits, phenolic composition, vitamin C, and antioxidant activity. Multivariate analyses including PCA, HCA, and Pearson correlation were performed to classify genotypes and determine trait relationships. The first two PCA components explained 51.9% of the total variation. Antioxidant-related traits mainly contributed to PC1, whereas berry size and anthocyanin content influenced PC2. HCA grouped the genotypes into distinct clusters according to antioxidant capacity and pomological characteristics. Correlation analysis showed significant positive relationships among antioxidant-related parameters. Berry size traits were positively correlated with each other, but negatively associated with seed number and skin thickness. The combined use of pomological, biochemical, and multivariate analyses proved useful for genotype classification. The identification of antioxidant-rich genotypes may support future breeding and conservation studies. The results highlight the importance of indigenous grape germplasm for sustainable viticulture.

    • SDG 2 · Açlığa Son
  • MakaleAçık Erişim2025Scopus SJRQ1
    Pomological and Biochemical Properties of Blackberry (Rubus fruticocus) Genotypes

    Dogan, Hande; Aglar, Erdal; Ozturk, Burhan; Tekin, Onur; Alan, Davut; Sumbul, Ahmet

    The aim of this study was to examine the genotypes of wild blackberries growing naturally in Tunceli province in terms of fruit characteristics and to determine the ones with superior characteristics. Nine different genotypes were determined by population screening and 100 fruits were collected from each genotype. The physical properties such as fruit weight, length, width, as well as color, chemical content, and antioxidant properties were examined. Statistically significant differences were found among the genotypes; fruit weight, length, and width varied between 0.71 and 1.19 g, 10.08 and 12.63 mm, and 12.25 and 14.33 mm, respectively. The G9 genotype had the largest fruits, and the G6 genotype had the smallest fruits. In fruit color analyses, significant differences were observed among the genotypes, and the G2 genotype stood out with the highest L* value (20.05), but G9 had the lowest a* value (0.92). Total soluble solids (TSS) content varied between 11.95% in G2 and 21.10% in G7. Vitamin C content was highest in the G6 genotype (54.46 mg 100 g−1), while G9 had the lowest vitamin C content (22.66 mg 100 g−1). Significant differences were also observed among the genotypes in terms of phenolic content, flavonoids, anthocyanins, and antioxidant activity. As a result, in this study, significant differences in organic acid contents were determined among wild blackberry genotypes in Tunceli province. The G1 genotype was the richest in malic acid, while the G6 was the genotype with the highest ascorbic acid level. Various differences were also found among the genotypes in terms of oxalic acid, citric acid, and other organic acid contents. These findings may constitute an important resource in determining the commercial production and potential health benefits of wild blackberries. In the selection of blackberry genotypes, consideration of these organic acid contents is important, especially in terms of taste and nutritional value.

    • SDG 2 · Açlığa Son
    AtıfScopus3OpenAlex1
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2025Scopus SJRQ1
    Quality preservation of jujube fruit during cold storage: effect of maturity stage and modified atmosphere packaging

    Gun, Sefa; Ozturk, Burhan; Aglar, Erdal; Karakaya, Orhan

    Bacground: This study, which examines the effect between the maturity stage and modified atmosphere packaging (MAP) in order to prevent post-harvest quality losses and extend the storage life of jujube (Ziziphus jujuba Mill.) fruit, offers an important contribution to supply chain management. The fruits harvested at different maturity stages were stored at 0 ± 0.5 °C and 90 ± 5 RH in MAP and control conditions for 42 d and changes in quality, physiological and biochemical parameters were evaluated. Results: The lowest value was recorded in the early maturity (M-1) + MAP group for weight loss. Respiration rate decreased with advancing maturity, MAP treatments slowed down this process. Oxygen consumption and CO₂ production changed according to maturity level, MAP applications balanced gas exchange. MAP maintained brightness and color intensity of the fruit better. It also slowed down the firmness loss. The highest soluble solid content (SSC) was determined in the late maturity (M-3) + MAP group. Titratable acidity (TA) showed lower increase in MAP treatments. MAP significantly reduced the losses of vitamin C. Total phenolic, total flavonoids and antioxidant activity decreased during storage, while MAP treatments limited this decrease. Conclusions: The findings revealed that packaging jujube fruit with MAP, especially in early and mid-maturity stages, better preserves its quality parameters. Accordingly, MAP applications appropriate to the ripeness stage are recommended as an effective strategy to extend the fresh consumption period of jujube fruit and preserve its bioactive compounds.

    • SDG 2 · Açlığa Son
    AtıfScopus6WoS5OpenAlex5
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2024
    Investigation of Flower, Leaf, and Stem Parts of Three Gundelia Species Growth in the Eastern Anatolia Region of Türkiye from a Biochemical Perspective

    Yilmaz, Fatih; Türkoglu, Ismail; Kirmizikaya Özmen, Gorkem; Yüce Babacan, Ebru; Yilmaz, Okkes

    13 species of Gundelia species plants are endemic in T & uuml;rkiye and are frequently used by the public for both nutrition and medicinal objectives. In this study, three parts (flower, leaf, and stem) of three species of Gundelia ( G.dersim , G.glabra, and G.munzurensis) were biochemically investigated. DPPH and ABTS analyses for antioxidant activity were performed on methanol extracts of plant parts. As a result of both analyses in parallel, the flower part of G.munzurensis had the highest %Inhibition value (DPPH:91.85 +/- 0.78; ABTS:97.38 +/- 0) (P<0.001). In total phenolic (29.09 mg GAE/g) and total flavonoid (5.59 mg CE/g) measurements, the highest amount was found statistically quite significant (P<0.001) in the leaf part of G.munzurensis. Gallic, vanillic, ferulic, romantic, and cinnamic acids, which are phenolic acids and of the flavonoids, rutin, catechin, naringin, and naringenin, were determined in all plant parts. Vitamin D3, alpha-tocopherol, ergosterol, stigmasterol, and beta-sterol were detected in parts of all plant species. While palmitic (16:0), palmitoleic (16:1), stearic (18:0), oleic (18:1), linoleic (18:2), and linolenic (18:3) fatty acids as the main fatty acids were detected in all parts of the three Gundelia species, lauric (12:0), tridecanoic (13:0), myristic (14:0), pentadecanoic (15:0), cis-10-pentadecanoic (15:1), heptadecanoic (17:0), cis-10heptadecanoic (17:1), and eicosanoid (21:0) acids were also identified at different concentrations. Considering the biochemical properties of Gundelia species, it shows that they can be consumed as food and also used pharmacologically.

    • SDG 2 · Açlığa Son
    AtıfOpenAlex1
    Web of ScienceTR Dizinİncele
  • MakaleYalnız künye2022Scopus SJRQ1
    In vivo and in vitro evolution of the effects of cypermethrin on turbot (Scophthalmus maximus, Linnaeus, 1758) spermatozoa

    Beken, Atife Tuba; Saka, Şahin; Aydın, İlhan; Fırat, Kürşat; Suzer, Cüneyt; Benzer, Fulya; Erişir, Mine; Özden, Osman; Hekimoğlu, Müge Aliye; Engin, Serhat

    Synthetic pyrethroid pesticide is commonly used in agricultural activities in the Black Sea region during reproduction period of turbot. In this sense, in vivo and in vitro studies have shown that cypermethrin (CYP) could be one of the environmental factors affecting decreasing turbot stocks. In this study, effects of in vivo and in vitro administration of CYP, a synthetic pyrethroid, on sperm kinematics motility (MOT), progressive motility (PM), curvilinear velocity (VCL), straight line velocity (VSL), average path velocity (VAP), linearity (LIN), straight line velocity (STR), amplitude of lateral head (ALH), beat cross frequency (BCF), oxidative stress biomarkers malondialdehyde (MDA), reduced glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and lipid peroxidation (LPO) and also histopathological alterations in gonads were investigated in spermatazoa of turbot (Schopthalmus maximus). Broodstock was supplied from culture origin and used in spawning season, additionally, two (0, 0.187 and 0.218 ppb) and three (0, 1.025, 2.05 and 4.1 ppb) different CYP concentrations were performed for in vivo and in vitro studies, respectively. In vivo and in vitro studies, significant reductions were found in sperm MOT, PM, VCL, VSL, VAP, LIN, and ALH properties depend on the increase in CYP concentrations (p < 0.05). Besides, activities of GSH, GPx, SOD, and CAT increased. In terms of histological alterations, no difference was observed among groups (0, 0.187 and 0.218 ppb) in the maturity stage of the germ cells. According to obtained results, sperm kinematics was affected significantly with increased the dose levels of CYP (p < 0.05).

    • SDG 2 · Açlığa Son
    AtıfScopus6OpenAlex8
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2021Scopus SJRQ2
    Investigation of spectroscopic, thermal, and biological properties of FeII, CoII, ZnII, and RuII complexes derived from azo dye ligand

    Turan, Nevin; Buldurun, Kenan; Adiguzel, Ragip; Aras, Abdülmelik; Turkan, Fikret; Bursal, Ercan

    In this study, the novel azo dye FeII, CoII, ZnII, and RuII complexes with an azo dye ligand (L: (E)-4-((4-methoxyphenyl)diazenyl)-3-methyl-1H-pyrazol-5-amine) were synthesized. The structures of the complexes were characterized by FT-IR, elemental analysis, UV-Vis, mass spectra (FeII and CoII), NMR spectra (only diamagnetic ZnII and RuII), thermogravimetric and differential thermal analysis (TGA-DTA). All of the newly synthesized compounds were tested for their biochemical properties, including enzyme inhibitory and antioxidant activities. According to the in vitro ABTS, DPPH, CUPRAC, and FRAP antioxidant methods, the ligand and its metal complexes showed close antioxidant activities to the standards (BHA, BHT, ascorbic acid, and α-tocopherol). Enzyme inhibitions of the metal complexes were investigated against glutathione S-transferase (GST), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzymes. The best inhibition values (Ki) were observed for Ru(II) complex against GST (14.36 ± 2.16 µM), AChE (16.86 ± 2.74 µM), and BChE (14.12 ± 2.04 µM).

    AtıfScopus45WoS45OpenAlex45
    ScopusWeb of Scienceİncele
  • MakaleYayıncıda açık erişim2020Scopus SJRQ4
    Assessment of elemental content, antioxidant activity, and total phenolic content of vitis sylvestris gmelin

    Ayhan, Nagihan Karaaslan

    In this study, we determined the Cu, Fe, Mn, and Zn contents of Vitis sylvestris Gmelin using flame atomic absorption spectrometry (FAAS), and examined the antioxidant properties of Vitis sylvestris Gmelin using radical scavenging capacities and total phenolic content tests. We found the average elemental contents; Cu, Fe, Mn, and Zn as 1.506 ± 0.042 mg/kg, 0.796 ± 0.020 mg/kg, 2.333 ± 0.033 mg/kg, and 3.191 ± 0.262 mg/kg, respectively. When we examined the antioxidant activity tests applied to different extracts, we determined the highest extraction yield with the methanol extract. DPPH radical scavenging activity, ABTS radical scavenging activity, and total phenolic content values in methanol extract were determined to be respectively 3.957 ± 0.146 mg TEAC/g fw, 9.062 ± 0.273 mg TEAC/g fw, and 2.365 ± 0.028 mg GAE/g fw. When we evaluated the antioxidant activity and total phenolic content results for all extracts statistically, we determined that there was generally a statistically significant difference between each extract (p < 0.01). Vitis sylvestris Gmelin has high antioxidant content when considering the data obtained. Also, we determined that it is an effective candidate in the protection against reactive oxygen species.

    • SDG 2 · Açlığa Son
    AtıfScopus2OpenAlex3
    ScopusTR Dizinİncele
  • MakaleYalnız künye2019Scopus SJRQ2
    A comprehensive study about Hibiscus sabdariffa leaves: antioxidant activity, polyphenol profile and macro- and micro-element content

    Karaaslan, Nagihan M.

    Hibiscus sabdariffa leaves are generally consumed by people in cold drinks and herbal tea. The purpose of this study is to examine in terms of antioxidant activity, polyphenol profile and macro- and micro-element content of H. sabdariffa leaves. Firstly, antioxidant activity studies were carried out by applying antioxidant activity assays to different extracts of the plant leaves. It has been observed that the antioxidant activity results vary depending on the extraction solvent and that the result obtained for one extract in some tests could not be obtained for the same extract in the other tests when solvents are changed. Secondly, the polyphenol profile of this plant was identified with a high-performance liquid chromatography–diode array detector (HPLC–DAD). For this purpose, thirteen polyphenols were examined in leaves of this plant, but only caffeic acid, chlorogenic acid, ellagic acid, p-coumaric acid and quercetin were detected among the studied polyphenols. Finally, macro-element including calcium (Ca), potassium (K), magnesium (Mg), sodium (Na) and micro-element including copper (Cu), iron (Fe), zinc (Zn) analysis was carried out using flame atomic absorption spectrometry (FAAS).

    AtıfScopus9WoS8OpenAlex10
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2018Scopus SJRQ3
    Effects of conventional and organic rearing systems and hen age on oxidative stress parameters of blood and ovarian tissues in laying hens; [Konvansiyonel ve organik yetiştirme sistemleri ile tavuk yaşının yumurta tavuklarının kan ve yumurtalık dokusundaki oksidatif stres parametreleri üzerine etkisi]

    Şimşek, Ülkü Gülcihan; Baykalir, Yasin; Erişir, Mine; Benzer, Fulya

    In this study, effects of hen age and rearing systems on some oxidative stress parameters in serum and ovarian tissues of hens are investigated. For this purpose, total of 48 Bovans White commercial laying hybrids from two different rearing systems (conventional cage and organic) at 30 and 60 weeks of age were used. Serum and ovarian tissues of the hens were collected following slaughter process and malondialdehyde (MDA), glutathione (GSH), glutathione peroxidase (GSH-Px) and catalase (CAT) levels of serum and ovarian tissues were determined. MDA levels of serum was found significantly higher in conventional system, both in 30 and 60 weeks old (P<0.05). GSH-Px activity was lower, conversely CAT activity was significantly higher in conventional system (P<0.05). Hen age didn’t affect MDA, GSH, GSH-Px and CAT levels of serum (P>0.05). In addition, there weren’t any significant interactions between rearing system and hen age in serum (P>0.05). MDA (P=0.010) and GSH (P<0.01) levels of ovarian tissue were found significantly higher in conventional system while GSH levels of ovarian tissue had increased in 60 weeks old (P<0.01). GSH-Px and CAT activity was similar between groups (P>0.05). Interaction between rearing system and hen age affected activity of CAT in ovarian tissue (P<0.05). As a result, conventional battery cages caused oxidative stress interrelated with increasing lipid peroxidation and MDA levels in laying hens. Antioxidant enzymes that play role in reduction of MDA were inadequate in this system. Oxidant/antioxidant balance can be established at 30 or 60 weeks of age by hen organism and therefore MDA levels of tissues would not be affected by age.

    • SDG 2 · Açlığa Son
    AtıfScopus5WoS5OpenAlex5
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2017Scopus SJRQ3
    Characterization of antioxidant activity, vitamins, and elemental composition of ciris (Asphodelus aestivus L.) from Tunceli, Turkey

    Unal, Ilkay; Kaplan Ince, Olcay

    Ciris (Asphodelus aestivus L.), which has been used for a wide range of medicinal purposes and is indigenous in Tunceli, Turkey, was collected from the eastern and western parts of the city. The goal of this study was to determine the vitamins, essential elements, and antioxidant activity of this natural product. The 2,2-diphenyl-1-picrylhydrazyl-hydrate radical scavenging activity, metal chelating activity, reducing power, total phenolics, and Vitamin A, Vitamin C, sodium, potassium, phosphorus, magnesium, calcium, copper, manganese, and zinc concentrations were determined in ciris extracts. The concentrations of Vitamin A, Vitamin C, and Mn of ciris from west Tunceli were higher than samples from the east.

    • SDG 2 · Açlığa Son
    AtıfScopus7WoS7OpenAlex8
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2015Scopus SJRQ3
    An investigation on antioxidant and antimicrobial activities of four Inula helenium L. taxa

    Albayrak, S.; Cinar, A. E. Korkmaz; Paksoy, M. Y.; Aksoy, A.

    The antioxidant activities of methanol (ME), ethanol (EE), water (WE) and ethyl acetate (EAE) extracts of four Inula helenium L. taxa (I. helenium ssp. orygalis (Boiss.) Grierson, I. helenium ssp. pseudohelenium Grierson, I. helenium ssp. turcarasemosa Grierson and I. helenium ssp. vanensis Grierson) were investigated. The phosphomolybdenum assay, beta-carotene linoleate bleaching and DPPH radical scavenging activity were used to evaluate the antioxidant capacity. The total phenolic contents determined by Folin-Ciocalteu assay of the extracts ranged from 4.18 to 102.91 mg gallic acid equivalents (GAE)/g dry extract. The extracts showed considerable effect on reducing the oxidation of beta-carotene. The highest radical scavenging activity was obtained for ME of I. helenium ssp. orygalis in DPPH assay. ME, EE and EAE of four Inula helenium taxa showed significant antibacterial activity against 13 bacteria tested. WEs had no inhibitory effect against bacteria tested except for I. helenium ssp. orygalis. EE of I. helenium ssp. orygalis was only effective against C. albicans.

    AtıfWoS8
    Web of Scienceİncele
  • MakaleAçık Erişim2014
    The investigation of some bioactive compounds and antioxidant properties of hawthorn (Crataegus monogyna subsp. monogyna Jacq)

    Keser, Serhat; Celik, Sait; Turkoglu, Semra; Yilmaz, Okkes; Turkoglu, Ismail

    The antioxidant and pharmacological effects of hawthorn have mainly been attributed to the polyphenolic contents. The aim of this research is to determine some bioactive compounds and antioxidant properties of hawthorn aqueous and ethanol extracts of leaves, flowers, and ripened fruits. Materials and Methods: For this purpose, antioxidant activities of extracts were assessed on DPPH center dot, ABTS center dot +, superoxide scavenging, reducing power and ferrous metal chelating activity assays and phenolic content of extracts was determined by Folin-Cioacalteu's reagent. Results: The flavonoids including rutin, apigenin, myricetin, quercetin, naringenin and kaempferol, were identified by high- performance liquid chromatography in the hawthorn extract. Conclusion: It was observed the aqueous and ethanol extracts of Crataegus monogyna subsp. monogyna fruits showed the highest activity in reducing power and metal chelating activity assays. In addition, it was determined that the aqueous flower extract showed higher flavonoid content than aqueous leaves extract. The antioxidant and pharmacological effects of hawthorn have mainly been attributed to the polyphenolic contents.

    AtıfWoS47OpenAlex58
    Web of Scienceİncele
  • MakaleYalnız künye2014Scopus SJRQ2
    Essential Oil Composition, Antioxidant and Antifungal Activities of Salvia sclarea L. from Munzur Valley in Tunceli, Turkey

    Yuce, E.; Yildirim, N.; Yildirim, N. C.; Paksoy, M. Y.; Bagci, E.

    The essential oil composition and in vitro antioxidant and antifungal activity of the Salvia sclarea L. from Munzur Valley in Tunceli, Turkey were evaluated in this research. The in vitro antifungal activity of ethanol, hexane and aqueous extracts of S. sclarea against pathogen fungi Epicoccum nigrum and Colletotrichum coc-codes were investigated. The essential oil of aerial parts of S. sclarea was obtained by hydrodistillation and was analysed by GC and GC-MS. Total antioxidant status was determined by using Rel assay diagnostics TAS assay kit (Lot. RL024) by Multiscan FC (Thermo). 33 compounds were identified representing the 85.0% of the total oil. The most abundant components (> 5%) of the S. sclarea essential oils were caryophyllene oxide (24.1%), sclareol (11.5%), spathulenol (11.4%), 1H-naphtho (2,1,6) pyran (8.6%) and beta-caryophyllene (5.1%). The best antifungal and antioxidant effect was seen in ethanolic S. sclarea extract. It can be said that Salvia sclerae could be used as natural antioxidant.

    AtıfWoS26
    Web of SciencePubMedİncele
  • MakaleYalnız künye2013Scopus SJRQ3
    EVALUATION OF ANTIOXIDANT PROPERTIES, ELEMENTAL AND PHENOLIC CONTENTS COMPOSITION OF WILD NETTLE (Urtica dioica L.) FROM TUNCELI IN TURKEY

    Yildirim, N. C.; Turkoglu, S.; Ince, O. K.; Ince, M.

    Wild nettle (Urtica dioica L.) types were sampled from different geographical regions in Tunceli (Turkey) to determine their mineral, vitamin, phenolic contents and their antioxidant properties. The total phenol varied from 37.419 +/- 0.380 to 19.182 +/- 1.00 mg of GAEs g(-1) of dry nettle. The highest radical scavenging effect was observed in Mazgirt parting of the ways 7.5 km with 33.70 +/- 0.849 mg mL(-1). The highest reducing power was observed in the nettles from Mazgirt parting of the ways 7.5 km. Among the various macronutrients estimated in the plant samples, potassium was present in the highest quantity followed by calcium and phosphate. Kaempferol and resveratrol were not determined in some nettle samples but rutin levels were determined in all samples. Vitamin A concentrations were ranged between 13.64 +/- 1.90 and 5.74 +/- 1.00 (mg kg(-1) dry weight). These results show that Urtica dioica L. collected from Tunceli in Turkey could be considered as a natural alternative source for food, pharmacology and medicine sectors.

    AtıfWoS11
    Web of Scienceİncele