Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Gul, Muhammet(85)
- Serdar, Osman(72)
- Güler, Ömer(68)
- Akkurt, Nevzat(61)
- Baskonus, Haci Mehmet(54)
- Alataş, Mevlüt(53)
- Paksoy, Mehmet Yavuz(53)
- Yucesan, Melih(53)
- Bulut, Hasan(51)
- Tekin, H.O.(51)
- ALMisned, Ghada(48)
- Yildirim, Numan(48)
- Benzer, Fulya(47)
- Kocabaş, Mehmet(45)
- Yildirim, Nuran Cikcikoglu(44)
- Kutlu, Banu(41)
- Ince, Muharrem(39)
- Zengin, Gokhan(39)
- Batan, Nevzat(37)
- Utku, Anıl(35)
- Celik, Erkan(33)
- Topal, Murat(32)
- Ezer, Tülay(31)
- Tanyol, Mehtap(31)
- Can, Erkan(30)
- Sulaiman, Tukur Abdulkadir(29)
- Aslan, Naim(28)
- Özkul, İskender(28)
- Aslan, Alper(27)
- Cakilcioglu, Ugur(27)
- Erguven, Gokhan Onder(27)
- Kutluyer, Filiz(27)
- Kök, Mediha(27)
- Ates, Mehmet(26)
- Erten, Fusun(26)
- Kahraman, Gökhan(26)
- Onat, Onur(26)
- Dal, Nursel Alp(25)
- Danabas, Durali(25)
- Say, Yakup(25)
Yayınlar
- MakaleYalnız künye2023Scopus SJRQ3Evaluation of social factors within the circular economy concept for European countries
Kaya, Sema Kayapinar; Ayçin, Ejder; Pamucar, Dragan
The circular economy (CE) is a rapidly growing theme, particularly in the European Union (EU), that encourages the responsible and circular use of resources in the field of contributing to long-term development. The environmental and economic magnitude of development are frequently debated in the subject of CE whereas, social aspects have been only rarely and sporadically combined into the CE. Therefore, this study involves a multidisciplinary holistic framework of clustering methods and Multi-Criteria Decision Making (MCDM) for evaluating the CE paradigm in relation to EU countries' social growth. In terms of the social impact of CE strategies, the k-means cluster analysis was used to group the 27 EU members with similar social impact levels. Subsequently, a novel integrated CRITIC (The criteria importance through intercriteria correlation) and MEREC (Method based on the Removal Effects of Criteria) methods were employed for determining the weights of social indicators in order to balance the two weighting methods. In order to select the best country in each cluster, a novel extension of the hybrid MARCOS (Measurement of Alternatives and Ranking according to Compromise Solution) method combined with Power averaging and Heronian operator was developed. According to final solutions, Western European countries in the first cluster have the lowest unemployment and corruption rates, with the Netherlands having the best performance in this cluster. The second cluster includes countries with the lowest employment rates following university graduates between the ages of 20 and 64. Accordingly, Croatia is the best social performance in this cluster. Countries with the highest income distribution and unemployment rate are in the 3rd cluster, the best country in this group is Lithuania. Finally, the results obtained from the innovative MCDM methods have validated in order to demonstrate the proposed methodology's applicability.
AtıfScopus30WoS23OpenAlex42
İncele - MakaleAçık Erişim2023Scopus SJRQ2Internal deformation of continental blocks within converging plates: insights from the Ovacık Fault (Anatolia, Türkiye)
Zabci, Cengiz; Sançar, Taylan; Tikhomirov, Dmitry; Ivy-Ochs, Susan; Vockenhuber, Christof; Friedrich, Anke M.; Yazici, Müge; Akçar, Naki
The active tectonics of Anatolia is mostly characterized by its westward motion with respect to Eurasia between the Hellenic subduction in the west and Arabia-Eurasia continental collision in the east. Although most of the deformation is suggested to be confined along Anatolia’s boundary elements, viz. the North and East Anatolian shear zones, recent studies indicate a higher magnitude of internal strain accumulation, especially along the parallel/subparallel strike-slip faults of its central province. We present the first morphochronology-based slip rate estimate for one of these strike-slip structures, the Ovacık Fault, by using cosmogenic36Cl dating of offset fluvial deposits. At the Köseler Site (39.3643°N, 39.1688°E), two faulted risers, bounding the alluvial fan with its subplanar surface (NF1/NF1’) and the inset terrace tread (NF1/T2), are offset 19–24 and 15–22 m, respectively. The scattered surface ages and variability of 36 Cl concentrations in depth profiles suggest strong evidence for inheritance in alluvial fan and terrace deposits; thus, we used modelled depth-profile ages for both surfaces. The modelled ages 8–10 ka for NF1 and 6–8 ka for T2 yield slip-rate estimates 2.4 +0.5/–0.4 mm/a and 2.8 +0.7/–0.7 mm/a, respectively, for the upper-tread reconstruction of the NF1/NF1’and the lower-tread reconstruction of the NF1/T2. Our results together with previous slip-rate estimates for other structures show a significant internal deformation for Anatolia, especially along its subparallel strike-slip faults. These secondary faults slice Anatolia into several pieces giving rise to the formation of the Malatya-Erzincan, Cappadocian, and Central Anatolian slices, where the geometry is strongly controlled by the distribution of the Tethyan accretionary complexes.
AtıfScopus3OpenAlex3TR Dizin1
İncele - MakaleYalnız künye2023Scopus SJRQ2On the copula-based reliability of stress-strength model under bivariate stress
Hudaverdi, Burcu; Susam, Selim Orhun
In this paper, we consider the stress-strength reliability (Formula presented.) where the strength Y of a component lies between the dependent stress variables (Formula presented.) and (Formula presented.). We propose a copula-based approach for stress-strength reliability having bivariate stress. We obtain R for Farlie-Gumbel-Morgenstern copula with Burr III marginals. Also, we propose a Bernstein copula approximation for evaluating R under the stress-strength setup. We present empirical and maximum likelihood-based estimation procedures and compare their performances by Monte Carlo simulation. We apply the proposed approach to chemical and overt diabetes data for illustration purpose.
AtıfScopus12WoS12OpenAlex11İncele - MakaleAçık Erişim2023Scopus SJRQ3Synthesis, Characterization, Antimicrobial and Time Killing Activities of New SulfaDerived Schiff Bases Coordinated with Cu(II)
İdil, Önder; Şahal, Hakan; Canpolat, Erdal; Özkan, Mustafa
Synthesis of three Schiff bases of 5-bromo-3-nitro salicylaldehyde containing different sulfonamide group antibiotic compounds and their Cu(II) complexes was carried out. Structures of all compounds were characterized with spectroscopic methods, including Fourier transform infrared, proton nuclear magnetic resonance, and elemental analysis. The in vitro antimicrobial activity of ligands and complexes against Gramnegative and Gram-positive bacteria and the yeast Candida albicans was evaluated. It was determined that the ligand and complexes showed outstanding antimicrobial activity against almost all of the microorganisms tested. It has been observed that the newly synthesized complexes have more antimicrobial effects than the corresponding ligands. It has been determined that the newly synthesized complexes have more antimicrobial effects than the others (E. coli, L. monocytogenes, and C. albicans), especially on Staphylococcus aureus and Pseudomonas aeruginosa.
AtıfScopus4WoS3OpenAlex2İncele - MakaleYalnız künye2023Scopus SJRQ2The protective effect of arbutin against potassium bromate-induced oxidative damage in the rat brain
Akkoyun, H. Turan; Uyar, Ahmet; Bayramoglu Akkoyun, Mahire; Bengü, Aydın Şükrü; Melek, Şule; Karagözoğlu, Fatma; Aydın, Sevinç; Ekin, Suat; Erdem, Sinem Aslan
This study aimed to investigate the protective effects of arbutin (ARB) against brain injury induced in rats with potassium bromate (KBrO3). The rats were divided into four groups as Group 1: Control (0.9% NaCl ml/kg/day p.), Group 2: KBrO3 (100 mg/kg (gavage), Group 3: ARB (50 mg/kg/day p.), and Group 4: KBrO3 + ARB (100 mg/kg (gavage) + 50 mg/kg/day p.). At the end of the fifth day of the study, the rats in all groups were killed, and their brain tissues were collected. In the collected brain tissues, malondialdehyde (MDA), superoxide dismutase (SOD), and catalase (CAT) levels were measured, and routine histopathological examinations were made. The MDA levels in the group that was exposed to KBrO3 were significantly higher than those in the control group (p ˂ 0.001). In comparison to the KBrO3 group, the MDA levels in the KBrO3 + ARB group were significantly lower (p ˂ 0.001). It was observed that SOD and CAT enzyme activity levels were significantly lower in the KBrO3 group compared to the control group (p ˂ 0.001), while these levels were significantly higher in the KBrO3 + ARB group than in the KBrO3 group (p ˂ 0.001). Additionally, the group that was subjected to KBrO3 toxicity, as well as ARB administration, had much lower levels of histopathologic signs than the group that was subjected to KBrO3 toxicity only. Consequently, it was found that KBrO3 exposure led to injury in the brain tissues of the rats, and using ARB was effective in preventing this injury.
AtıfScopus10
İncele - MakaleAçık Erişim2023Scopus SJRQ1Investigation of Critical Raw Materials in Sludge of Municipal Wastewater Treatment Plant
Topal, Murat; Arslan Topal, E. Işıl
In the present research, lanthanum, vanadium, tungsten, scandium, bismuth, antimony, gallium, phosphorus, magnesium, and cobalt from critical raw materials (CRMs) were monitored for one year in the sewage sludges from an advanced biological wastewater treatment plant with the aim of presentation of possibility of using sewage sludge as a secondary source of critical raw materials. The amounts of the critical raw materials in sewage sludge were calculated annually, and economic values were revealed. Maximum concentrations of lanthanum, scandium, tungsten, bismuth, antimony, gallium, vanadium, cobalt, magnesium, and phosphorus were 4.3, 1.6, 0.5, 1.51, 1.27, 1.7, 23, 5.6, 6500, and 16,170 mg/kg, respectively. In the sewage sludge, the amount of CRMs, which have been formed annually, have been listed as tungsten < scandium < antimony < bismuth < gallium < lanthanum < cobalt < vanadium < magnesium < phosphorus. In autumn, summer, spring, and summer season, the mean highest concentration was for P, while the minimum concentration was for W. In sewage sludge, P and W elements were the highest and the least of the CRMs, respectively. With the recovery of CRMs in sewage sludge, the highest theoric achievable income is for Mg, while the lowest income is for Sb. It is determined that a total of 26,083.8 USD/year could be obtained by recovering the CRMs mentioned here from the sewage sludge.
AtıfScopus1WoS1OpenAlex3İncele - MakaleYayıncıda açık erişim2023Scopus SJRQ3Contamination and Ecological Risk Assessment of Heavy Metals in Surface Sediments of the Munzur Stream, Turkey
Kutlu, Banu
The aim of the present study is to determine the heavy metal concentrations in the surface sediment between 2019-2020 in Munzur Stream,Turkey. The impact of pollution level in the study area was evaluated by geoaccumulation index (Igeo), Contamination Factor (CF), enrichment factor (EF), pollution ecological risk (PER) index, and pollution load index (PLI). The average amount of heavy metals detected in sediment in the study in mg/kg was, in descending order, Fe>Al>Mn>Ni>Cr>Zn >Cu>Pb>Cd>Hg. The data evaluated by several statistical methods indicated that the metals with a positive relationship between them in the Pearson correlation analysis and the elements of the same factor in the factor analysis were mostly the same. The comparison of the results with the sediment quality criteria showed that only the mean value of Mn and Ni exceeded the values of PEL. Heavy metal levels in Munzur Stream sediment exposed to domestic and agricultural wastes, agricultural fertilizers and pesticides, and mines were not high enough to pose a threat to aquatic life.
AtıfScopus9WoS8OpenAlex11İncele - MakaleYalnız künye2023Scopus SJRQ2Computational assesment of Carreau ternary hybrid nanofluid influenced by MHD flow for entropy generation
Ramzan, Muhammad; Ali, Farhan; Akkurt, Nevzat; Saeed, Anwar; Kumam, Poom; Galal, Ahmed M.
Tri-hybrid nano-particles in shear rate-dependent viscous fluid are essential for improving heat and mass transmission in many industries. The current study explores the two-dimensional flow of the Carreau-ternary hybrid nanoliquid with a magnetic field over the stretching surface. The heat transport mechanism is deliberated through the applications of thermal radiation and heat source/sink effects. The entropy minimization of the flow of Carreau ternary hybrid nanofluid has also been scrutinized. Further, the concepts of convective conditions are employed for the numerical solution of the existing model. In the present flow analysis, silver (Ag), Molybdenum disulfide (MoS2), and multi-wall carbon nanotube (MWCNT) nanoparticles are studied. Carboxymethyl cellulose (CMC-water) is used as a base liquid. The well-established numerical collocation finite difference scheme and three-stage Lobatto III as the built-in function of the bvp4c solver via MATLAB have been used to solve the system of equations in the form of concentration, energy, and momentum. Numerous features, such as flow speed, temperature, drag friction, and Nusselt number, are described in figures and tables. From the existing model, some key outcomes are that the rising values of the radiation parameter increased the heat transfer rates. Further, it is dissected that the greater importance of the magnetic field parameter declined the entropy generation and velocity of the liquid.
AtıfScopus88OpenAlex96İncele - MakaleAçık Erişim2023Scopus SJRQ1Radiation mechanism on dissipative ternary hybrid nanoliquid flow through rotating disk encountered by Hall currents: HAM solution
Shamshuddin, M.D.; Akkurt, Nevzat; Saeed, Anwar; Kumam, Poom
The energy transition to enhance heat transport during the flow of ternary hybrid nanofluid comprised of Copper (Cu), Iron oxide (Fe3O4), Silicon dioxide (SiO2) nanoparticles and Polymer as base liquid over a revolving disk surface has been reported. From the several existing techniques, adding nanoparticles to standard working fluids is an effective approach that might dramatically improve the rate of heat transfer. The Hall and radiation impacts are also considered. A mathematical model is developed by assuming the flow as incompressible and purely radial in a cylindrical coordinate system and appropriate similarity variables are introduced for problem simplification and dimensionless analysis. The solution of complex generated PDEs was calculated using semi analytical method known as Homotopy Analysis Method (HAM) after translating them into corresponding ODEs. It has been observed that the consequences of thermal radiation, dissipation term, unsteadiness and rotation parameters boost the energy transmission rate and enhances the heat transfer rate of tri hybrid nanofluids. However, Cu-Fe3O4 nanoparticles in the base fluid remarkably magnifies the energy transmission rate. The unitary ternary hybrid nanofluid (Cu, Fe3O4, SiO2) has higher velocity profiles as compared to unitary nano fluid (Cu) and hybrid nano-fluid (Cu-Fe3O4).
AtıfScopus133WoS121OpenAlex138İncele - MakaleAçık Erişim2023Scopus SJRQ3Evaluation of waste polyethylene terephalate in polyol and polyurethane production
Fırat, Tülay; Kar, Filiz
As technology advances and human population grows, we must meet our diverse needs while minimising harm to the environment. One solution is to prioritise recycling and using second-hand consumer goods. In this study, PET flakes were depolymerised by glycolysis using different molar ratios of glycol such as propylene glycol(PG), triethylene glycol(TEG) and polyethylene glycol(PEG 400) in the presence of two different catalysts: zinc acetate- zinc sulphate. As a result, glycated products (polyols-PO) were obtained. The obtained polyols were then used to synthesise polyurethane films (PU) via acetone process. The thermal and chemical characterisations of the polyurethane films (PU) were analysed. In similar studies, zinc acetate was used as a transesterification catalyst for the glycolysis process. In this study, the same process was carried out using zinc sulphate and zinc acetate. Zinc sulphate was found to be a cheaper and eco-friendlier catalyst alternative to zinc acetate for the glycolysis process.
AtıfOpenAlex1İncele - MakaleAçık Erişim2023Scopus SJRQ4COMPARATIVE ANALYSIS OF EMBROIDERY AND SCREEN-PRINTING TECHNIQUES FOR TEXTILE-BASED FREQUENCY SELECTIVE SURFACES; [TEKSTİL TEMELLİ FREKANS SEÇİCİ YÜZEYLER İÇİN NAKIŞ VE SERİGRAFİ TEKNİKLERİNİN KARŞILAŞTIRMALI ANALİZİ]
Üner, İbrahim; Can, Sultan; Gürcüm, Banu Hatice; Yilmaz, A. Egemen; Aksoy, Ertuğrul
Frequency Selective Surface (FSS) is a specialized structure used in the field of electromagnetic waves and radio frequency (RF) engineering. It is designed to exhibit selective transmission or reflection properties based on the frequency of the incident electromagnetic waves. This article describes the design, construction, and analysis of a textile-based band-stop frequency selective surface for use in the highly EM-polluted GSM, Wi-Fi, LTE, and WiMAX bands. A full-wave EM solver called CST Microwave Studio was used to develop and simulate the unit cell of the proposed FSS at the relevant frequency. In this study, embroidered and screen-printed textile based FSSs were designed. According to the results of this study, it was demonstrated that both embroidery and screen printing FSSs exhibit resonance at a frequency of 3.5 GHz. The screen printing method yielded the best results in terms of resonance frequency sensitivity, while the embroidery method showed a resonance frequency shift. It was observed that the stitch directions and density are important parameters in the embroidery method. Gaps between the embroidery paths in the production of embroidered FSSs resulted in differences from simulations due to the disruption of the structural integrity of the unit cell. Consequently, textile-based FSSs offer advantages over traditional FSSs. This study highlights the potential of textile FSSs as an effective means of reducing electromagnetic pollution, and suggests that further improvements in the design and production processes of textile FSSs can be made.
AtıfScopus2OpenAlex4İncele - MakaleAçık Erişim2023Deterioration analysis of historical village house structure in Mersin Kanlıdivane archaeological area by UAV method
Karataş, Lale; Dal, Murat
The village house located in the Mersin Kanlıdivane archaeological site is one of the oldest settlements in the ruins, built in the second century. The house is mainly built of a yellowish beige limestone. This stone, which is the main material of the building, shows many deterioration patterns today. The aim of the study is to determine the dominant deterioration pattern of the stones in the village house structure in the Mersin Kanlıdivane archaeological site and to investigate the source of the deterioration. In order to investigate the deterioration patterns in the structure, the images obtained by UAV photogrammetry were interpreted and the types of deterioration were mapped. In the study, it is seen that even the types of material problems based on the smallest detail can be determined based on virtual visual inspection, thanks to UAV photogrammetry, without observing the structure in situ with UAV photogrammetry. The findings obtained in the study shows that the color change and surface loss deterioration on the stone surfaces has reached advanced levels as a result of the structure's exposure to the strong climate-induced sun and water effects for centuries. The results of the study show that the main damage observed on the stone surface of the structure is caused by the erosion by the effect of water. Restoration methods should be tried to stabilize the deterioration and replace the most degraded stones. It is recommended to use water-repellent surface coatings to protect the natural stone, especially against the intense water effect in the building.
AtıfScopus3OpenAlex3İncele - MakaleYalnız künye2023Scopus SJRQ2Effect of Using Eccentric Braces with Different Link Lengths on the Seismic Demand of CFST Column-Composite Beam Frames Subjected to Near-Field and Far-Field Earthquakes
Etli, Serkan; Güneyisi, Esra Mete
In recent years, in the light of technological developments, the utilization of composite members that enable the use of superior properties of concrete and steel together in earthquake-resistant building design has become widespread. In this study, 5-, 8-, 10-, 13- and 15-story composite moment-resisting framed buildings were designed using composite beams and concrete filled steel tube columns. The effect of using steel braces and the variation of the link length of the eccentric steel braces on the seismic demand of the composite buildings were investigated. For this, eight different cases with braces were considered and compared with the bare structure. The first case had concentric braces (having no link), and the other seven cases had eccentric steel braces with different link lengths classified as short, medium and long. The nonlinear dynamic response of braced and non-braced composite structures was evaluated under the effect of earthquake groups of far-field, near-field with and without pulse effects. Each earthquake group includes ten different ground motion records. SeismoStruct which is a fiber element-based software was used in modeling and analysis of the structures. Seismic behavior of the case studied structures was investigated comparatively through the demand parameters such as the maximum inter-story drift ratios, the maximum roof drift ratios and the deformation states in the structural elements. It was observed that the inclusion of the steel braces provided significant gains in dissipating seismic energy acting through composite buildings and the beam/column deformations decreased considerably, depending on the length of the link and the height of the structure. In some cases, significant damage was monitored in the link members; however, this type of deformation was limited.
AtıfScopus3WoS3OpenAlex18İncele - MakaleYalnız künye2023Scopus SJRQ2Aluminum Recovery by Acid Leaching of Variously Enriched Pyrophyllite Ore: Effects of Pre-treatment Methods for Activation
Aydoğmuş, Ramazan; Erdemoğlu, Murat; Uysal, Turan
Effects of pre-treatment methods such as calcination for thermal activation and intensive milling for mechanical activation on the aluminum (Al) recovery by acid leaching of preliminarily enriched pyrophyllite ore via attrition scrubbing and froth flotation were investigated. XRD patterns of the calcined and the intensively milled samples were compared to determine the changes during the pre-treatment processes. Hot HCl solution was used for dissolution of aluminum to determine the Al recoveries from variously enriched and variously pre-treated pyrophyllite ore samples. Specific thermal and milling energies consumed per unit amount of ore were calculated, and the ideal activation method was suggested by comparing the activation methods in terms of energy consumption. Mechanical activation of the pyrophyllite concentrate obtained by attrition scrubbing rather than froth flotation was suggested for higher recoveries of aluminum from by acidic leaching. It was determined that operating cost (in terms of energy) of the mechanical activation is lower and aluminum recovery is higher than thermal activation. It was concluded that mechanical activation instead of thermal activation is more economical and environmentally friendly method.
AtıfScopus5WoS4OpenAlex5İncele - MakaleAçık Erişim2023Scopus SJRQ3Optimization of shape factor by the response surface method, and the effect on sphalerite flotation recovery
Uysal, T.
Various morphological parameters that affect the flotation recovery of sphalerite were modelled and optimized using the response surface method (RSM). The effects of roughness value, shape factor, and collector concentration were investigated using the central composite full design method. The results were evaluated by analysis of variance. The optimum roughening time was found to be 25 minutes, the optimum roughness value was 2.9071 μm, and the optimum collector concentration was 0.001 M. Using these values, a flotation recovery of 98.01% was obtained. Similarly, in shape factor studies, the optimum grinding time was 15 seconds, the optimum roundness value 0.7421, and the optimum collector concentration 0.0009 M, which resulted in a flotation recovery of 94.30%. The average error between the optimization results and the experimental results was estimated to be less than 6%, and the R2 values were greater than 90%. The study shows that RSM can be effectively applied in finding the economic optimum condition for obtaining maximum flotation recovery with minimum reagent consumption.
AtıfScopus2WoS2OpenAlex2İncele - MakaleYalnız künye2023Scopus SJRQ2A New S-box Generator Algorithm Based on 3D Chaotic Maps and Whale Optimization Algorithm
Artuğer, Fırat
Encryption provides security in cases such as storing confidential information or transmitting it over a network. Today, block cipher algorithms are generally used for encryption. Undoubtedly, one of the most important units of block cipher algorithms to ensure confidentiality is substitution box (s-box) structures. Because s-boxes are nonlinear structures, making the algorithm resistant to differential cryptanalysis. Therefore, the higher the nonlinearity value of the s-box, the stronger it will be. In this study, a new algorithm is proposed to generate s-boxes with high nonlinearity value. In the proposed algorithm, Lorenz and Chua systems, which are 3D chaotic maps, are used for the initial population. The s-boxes produced with these chaotic maps were then increased to 110.5 using the whale optimization algorithm (WOA). WOA is one of the important optimization algorithms developed in recent years and was used for the first time in s-box production in this study. Looking at the results of the analysis, the proposed method has outstripped most of the other existing studies, thanks to effective 3D chaotic maps and WOA.
AtıfScopus44WoS38OpenAlex45İncele - MakaleAçık Erişim2023Scopus SJRQ1Numerical simulation for peristalsis of Quemada fluid: A dynamic mesh approach
Ali, Shahbaz; Nadeem, Sohail; Akkurt, Nevzat; Ali Ghazwani, Hassan; Eldin, Sayed M.
Introduction: Flow dynamics due to the peristaltic pumping has been the topic of great interest for the researchers. But numerical and analytical analyses for the peristaltic motion are limited where flow domain is deformed real-time. Research on peristalsis has a limitation where theoretical aspects of walls motion are considered, neglecting the real time deformation of the walls. Objectives: This paper aims to propose a more reliable and accurate numerical methodology for peristaltic motions to address the above-mentioned challenge. Stream traces, velocities, and pressure drops along the tube is to be visualized more accurately. Methods: In present study a finite volume based dynamic mesh motion method is adopted to analyze the peristaltic motion of a non-Newtonian Quemada fluid in an axisymmetric channel. The walls and interior domain of the channel is dynamically deformed for a sinusoidal wave traveling on boundary. Results: Simulation of unsteady flow behavior for time t=0s to 2s and amplitude ratio Φ=0.2,0.4,and0.6. predicts fluid trapping phenomenon. Rotation of fluid particles is more prominent for higher amplitude ratios. Pressure gradient increases with increasing amplitude ratios. Conclusion: A novel dynamic mesh method is proposed for peristaltic pumping. It provides more accurate and more physical results for stream traces; pressure drops and velocities along the tube. A limited case of the study validates the theoretical and analytical results already presented in literature; hence the method is reliable.
AtıfScopus10OpenAlex12İncele - MakaleAçık Erişim2023Scopus SJRQ1Evaluation of pea/rice and amylopectin/chromium as an alternative protein source to improve muscle protein synthesis in rats
Ozdemir, Oguzhan; Erten, Fusun; Er, Besir; Orhan, Cemal; Komorowski, James R.; Sylla, Sarah; Perez Ojalvo, Sara; Sahin, Kazim
Background: A preclinical study reported that the combination of an amylopectin/chromium complex (ACr) of branched-chain amino acids (BCAA) significantly enhanced muscle protein synthesis (MPS). This study was conducted to determine the effects of the addition of ACr complex to a pea/rice (PR) protein on MPS, insulin, muslin levels, and the mTOR pathway in exercised rats. Methods: Twenty-four rats were divided into three groups: (i) exercise (Ex); (ii) Ex + PR 1:1 blend (0.465 g/kg BW); (iii) Ex + PR + ACr (0.155 g/kg BW). On the day of single-dose administration, after the animals were exercised at 26/m/min for 2 h, the supplement was given by oral gavage. The rats were injected with a bolus dose (250 mg/kg BW, 25 g/L) of deuterium-labeled phenylalanine to determine the protein fractional synthesis rate (FSR) one h after consuming the study product. Results: The combination of PR and ACr enhanced MPS by 42.55% compared to the Ex group, while Ex + PR alone increased MPS by 30.2% over the Ex group (p < 0.0001) in exercised rats. Ex + PR plus ACr significantly enhanced phosphorylation of mTOR and S6K1 (p < 0.0001), and 4E-BP1 (p < 0.001) compared to the Ex (p < 0.0001). PR to ACr also significantly increased insulin and musclin levels (p < 0.0001) in exercised rats. Additionally, compared to Ex + PR alone, Ex + PR + ACr enhanced mTOR (p < 0.0001) and S6K1 (p < 0.0001) levels. Conclusion: These data suggested that PR + ACr may provide an alternative to animal proteins for remodeling and repairing muscle by stimulating MPS and mTOR signaling pathways in post-exercised rats. More preclinical and clinical human studies on combining pea/rice and amylopectin/chromium complex are required.
AtıfScopus4OpenAlex4İncele - MakaleAçık Erişim2023Determination of Rutting Resistance of SBS and Warm Asphalt Additive Binders by the MSCR Test
Akpolat, Mustafa
The MasterLife PAV110 Warm Mix Asphalt (WMA) additive’s rutting resistance in pure and Styrene-Butadiene-Styrene (SBS)-modified binders was examined using MSCR testing. Multiple Stress Creep Recovery (MSCR) tests were conducted on seven binders. The study’s findings indicated that the incorporation of WMA resulted in an increase in the Jnr values of both pure binders and binders modified with SBS at stress levels of 0.1 and 3.2 kPa. This finding implies that the occurrence of rutting will be negatively impacted. On the other hand, the performance level categorization showed that WMA additives had no impact on the performance levels of pure and SBS-modified binders. Since the Jnr and average percentage Recovery (R) values at 3.2 kPa, 1%, and 1.5% PAV110 additives exhibited similar properties, it was determined that the optimum usage rate in terms of cost was 1%.
AtıfScopus2OpenAlex2İncele - MakaleAçık Erişim2023Scopus SJRQ2Unraveling the chemical profile, antioxidant, enzyme inhibitory, cytotoxic potential of different extracts from Astragalus caraganae
Kurt-Celep, İnci; Zengin, Gokhan; Uba, Abdullahi I.; Caprioli, Giovanni; Mustafa, Ahmed M.; Angeloni, Simone; Cakilcioglu, Ugur; Guler, Osman; Kaplan, Alevcan; Sharmeen, Jugreet
Six extracts (water, ethanol, ethanol-water, ethyl acetate, dichloromethane, and n-hexane) of Astragalus caraganae were studied for their biological activities and bioactive contents. Based on high-performance liquid chromatography-mass spectrometry (HPLC-MS), the ethanol-water extract yielded the highest total bioactive content (4242.90 µg g−1), followed by the ethanol and water extracts (3721.24 and 3661.37 µg g−1, respectively), while the least total bioactive content was yielded by the hexane extract, followed by the dichloromethane and ethyl acetate extracts (47.44, 274.68, and 688.89 µg g−1, respectively). Rutin, p-coumaric, chlorogenic, isoquercitrin, and delphindin-3,5-diglucoside were among the major components. Unlike the dichloromethane extracts, all the other extracts showed radical scavenging ability in the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay (8.73–52.11 mg Trolox equivalent [TE]/g), while all extracts displayed scavenging property in the 2,2-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) radical scavenging assay (16.18–282.74 mg TE/g). The extracts showed antiacetylcholinesterase (1.27–2.73 mg galantamine equivalent [GALAE]/g), antibutyrylcholinesterase (0.20–5.57 mg GALAE/g) and antityrosinase (9.37–63.56 mg kojic acid equivalent [KAE]/g) effects. The molecular mechanism of the H2O2-induced oxidative stress pathway was aimed to be elucidated by applying ethanol, ethanol/water and water extracts at 200 µg/mL concentration to human dermal cells (HDFs). A. caraganae in HDF cells had neither a cytotoxic nor genotoxic effect but could have a cytostatic effect in increasing concentrations. The findings have allowed a better insight into the pharmacological potential of the plant, with respect to their chemical entities and bioactive contents, as well as extraction solvents and their polarity.
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