Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleYalnız künye2026Scopus SJRQ2
    Compositional control of structural, magnetic, and gamma-ray attenuation properties in rare-earth substituted Ho-based double perovskite oxides synthesized via mechanical alloying and oxidation

    Özkul, İskender; Kalay, Ece; Güler, Seval Hale; Karaduman, Oktay; Şimşek, Telem; Bülbül, Zeynel Abidin; Aksu Canbay, Canan; Sen Baykal, Duygu; ALMisned, Ghada; Tekin, H.O.

    Rare-earth substitution provides a route for tailoring the structural, magnetic, and gamma-ray attenuation behaviour of Ho-based Co-Mn double perovskites; however, the combined effects of rare-earth ionic size, magnetic character, and substitution level remain insufficiently understood. In this study, Ho1.5La0.5CoMnO6, Ho1.2Er0.8CoMnO6, Ho1.3Sm0.7CoMnO6, and Ho2CoMnO6 were synthesized through a two-step route involving mechanical alloying to obtain precursor powders, followed by annealing at 1000 °C in air to promote oxidation and double-perovskite phase formation. Their structural, thermal, surface-chemical, magnetic, and gamma-ray attenuation properties were examined by X-ray diffraction, thermal analysis, X-ray photoelectron spectroscopy, SEM-EDS, vibrating-sample magnetometry, and theoretical shielding calculations based on half-value layer (HVL) and transmission factor (TF) parameters. The XRD patterns were consistent with predominantly monoclinic P21/n type double-perovskite structures, while weak additional reflections suggested possible minor secondary phases. SEM-EDS showed homogeneous elemental distributions, and XPS analysis indicated Co2+ dominated and mixed Mn-valence characteristics in the spectra where reliable component analysis was possible. All compositions exhibited a low-temperature ferromagnetic-like field response but did not reach magnetic saturation at 3 T. Ho2CoMnO6 and Ho1.3Sm0.7CoMnO6 showed the highest field-dependent magnetization values at 10 K, whereas Ho1.2Er0.8CoMnO6 displayed the lowest response. The theoretical gamma-ray attenuation calculations showed clear composition-dependent differences. At 0.662 MeV, the HVL values were 1.0650, 0.9972, 1.0438, and 0.9967 cm for Ho1.5La0.5CoMnO6, Ho1.2Er0.8CoMnO6, Ho1.3Sm0.7CoMnO6, and Ho2CoMnO6, respectively. At the same photon energy and a thickness of 1.0 cm, the corresponding TF values were 0.0896, 0.0858, 0.0882, and 0.0860. Thus, Ho1.2Er0.8CoMnO6 and Ho2CoMnO6 exhibited the lowest HVL and TF values among the investigated compositions. The shielding calculations identified Ho1.2Er0.8CoMnO6 and Ho2CoMnO6 as the most effective attenuators, with lower HVL and TF values across the investigated energy range. These results show that rare-earth substitution enables compositional tuning of magnetic and theoretical gamma-ray attenuation behaviour, with the observed trends reflecting the combined influence of rare-earth ionic size, magnetic character, substitution level, and valence-state complexity.

  • MakaleYalnız künye2026Scopus SJRQ3
    Green revolution in nanotechnology: phytogenic CuO nanoparticles for biomedical and pharmaceutical applications

    Ceylan, Yusuf; Korkmaz, Nesrin; Kaçan, Fatma N.; Aydin, Ali; Korkmaz, Şengül A.; Yildirim, Ebru Ş.

    Copper oxide nanoparticles (CuO NPs) were synthesized using a green approach with Vitis vinifera L. extract, a plant rich in secondary metabolites that act as natural reducing agents. The obtained CuO NPs were characterized by XRD, EDX, and STEM analyses. FT-IR analysis revealed the presence of functional groups originating from plant biomolecules and confirmed the formation of Cu–O bonds, indicating the successful synthesis and stabilization of CuO NPs. XRD confirmed distinctive CuO diffraction peaks at 32.38°, 35.35°, 38.61°, 40.75°, 48.79°, 51.90°, 57.66°, 61.38°, 65.94°, and 75.12°. STEM imaging showed predominantly spherical, well-dispersed nanoparticles with an average size of 23–38 nm. Antibacterial analysis revealed a minimum inhibitory concentration (MIC) of 4 µg mL−1 against Escherichia coli ATCC 25922. In anticancer assays, the CuO NPs demonstrated notable cytotoxicity at both low concentrations and even at levels below the control group in A549, Calu-1, and Saos-2 cancer cell lines, highlighting their strong biomedical potential.

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  • MakaleYalnız künye2026Scopus SJRQ1
    The Effect of Women’s Menstrual Attitudes and Hygiene Practices on Self-Care Behaviors

    Yeyğel, Çiler; Yeşiltepe, Akgün

    Objective: While menstrual attitudes and hygiene practices are often examined in the literature through informational, risk-based, and cultural lenses, studies that directly address their holistic relationship to self-care behaviors remain limited. This study aims to investigate the impact of women’s menstrual attitudes and hygiene practices on their self-care behaviors. Methods: This is a cross-sectional analytical study. The study was completed between 5 October 2024 and 23 January 2025, with 700 women aged 18–49 in their reproductive period. Data were collected using a Demographic Information Form, the Menstrual Attitude Questionnaire, and the Self-Care Inventory. Spearman’s correlation analysis, the Mann-Whitney U test, and the Kruskal-Wallis test were used for data analysis. To examine nonlinear relationships and multivariable interactions, a Random Forest regression analysis was performed. Results: A positive and statistically significant relationship was found between menstrual attitudes and overall self-care (r = 0.132, p < 0.001). MAQ scores did not differ significantly across variables (p > 0.05). However, SCI scores showed significant differences based on menstrual hygiene education status, type of underwear used during menstruation, hand hygiene practices, and frequency of menstrual material use (p < 0.05). According to the Random Forest regression model, menstrual attitudes were identified as the strongest predictor of self-care behaviors. Conclusions: The results of this study supported the positive influence of women’s menstrual attitudes and hygiene practices on their self-care behaviors. The relationships between self-care and parameters such as menstrual hygiene education, frequency and type of menstrual material use, and hand hygiene during menstruation were clearly demonstrated. Given the limited number of studies in this field, randomized controlled trials and meta-analyses with high levels of evidence are recommended to generalize these results.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2026Scopus SJRQ2
    Adsorption of Reactive Red 120 dye from aqueous solutions using sepiolite clay with a channel-structured morphology: Mechanism, kinetics, isotherm, and thermodynamic studies

    Fırat, Tülay

    The effective treatment of dye-containing wastewater remains a major environmental challenge due to the high stability and solubility of reactive dyes. In this study, the adsorption behavior of Reactive Red 120 (RR120), an anionic reactive azo dye, from aqueous solutions was investigated using natural sepiolite clay possessing a channel-structured morphology. Batch adsorption experiments were performed to evaluate the effects of contact time (1–200 min), initial dye concentration (50–500 mg L−1), adsorbent dosage (0.1–1.5 g), solution pH (2–10), and temperature (25–50°C). The adsorption equilibrium was reached within approximately 75 min. The Langmuir isotherm provided the best fit to the equilibrium data, yielding a maximum monolayer adsorption capacity of 168.4 mg g−1 at 298 K. Thermodynamic analysis revealed that the adsorption process was spontaneous and endothermic, with an activation energy of 32.41 kJ mol−1. Adsorption kinetics were analyzed using pseudo-first-order, pseudo-second-order, and intraparticle diffusion models, while equilibrium data were evaluated using Langmuir, Freundlich, and Temkin isotherm models. The kinetic data were best described by the pseudo-second-order model, while thermodynamic analysis revealed that the adsorption process was spontaneous and endothermic. FTIR and XRD analyses further supported the important role of the channel-structured framework of sepiolite in RR120 adsorption. Unlike many clay-based adsorbents that require chemical modification, natural sepiolite exhibited high adsorption performance due to its intrinsic fibrous morphology, nano-channel structure, and high surface area. These findings demonstrate that natural sepiolite is a promising, low-cost, and sustainable adsorbent for the treatment of dye-contaminated wastewater.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 12 · Sorumlu Üretim ve Tüketim
  • BildiriYalnız künye2026
    LLM Based Software Test Scenario Generation System From Bug Descriptions

    Gundem, Merve Yilmazer; Karakose, Mehmet

    Large, user-interactive software systems require extensive software testing for safe deployment. Manually generated test cases by software testers require extensive time and effort, and their scope remains limited. In this study, a system based on LLM is proposed for automatic test cases and test steps generation from bug descriptions. In the proposed system, bug descriptions were first collected from the Defects4J Dataset. Keywords relevant to the bug scope were extracted from the descriptions. Structured automatic prompts were generated from the extracted keywords. The generated prompts were fed into the LLM as input, and software test cases appropriate for the bugs were generated. The method was evaluated on actual bug descriptions by comparing it to a general (baseline) prompt. Experimental results show that the lengths of the generated scenarios are similar, but the proposed method increases the keyword match rate with error descriptions to an average of 89 %. The findings reveal that keyword-driven prompts are effective in generating more reliable and error-specific test scenarios without requiring additional data.

  • MakaleYalnız künye2026Scopus SJRQ3
    A new lectin from Amanita vaginata mushroom with potent anti-inflammatory activity

    Seliman, Thoiba Mogahid Hussein; Ozsoy, Nurten; Altiparmak-Ulbegi, Gulsum; Alp-Kavlo, Hevidar; Arcan, Gulsah Gamze; Akev, Nuriye; Can, Ayse; Aksoy-Sagirli, Pinar

    This study used 80% ammonium sulphate fractional precipitation, followed by affinity chromatography to purify a new lectin (AVL) from the crude extract of the Amanita vaginata mushroom. The purification procedure achieved a 20% yield, a specific activity of 5120 HU/mg protein, and a 16-fold increase in purity. SDS-PAGE analysis showed a single band of 45 kDa. We assessed AVL's anti-inflammatory effect by measuring levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), induced by lipopolysaccharide (LPS), in RAW 264.7 macrophages. Western blot analysis showed that iNOS and COX-2 protein levels were barely detectable in the control groups, but markedly elevated in the LPS-treated groups. However, AVL treatment significantly inhibited the expression of both iNOS and COX-2 in LPS-stimulated cells. This effect was dose-dependent. These findings suggest that AVL's anti-inflammatory effects are mediated through the suppression of iNOS and COX-2 expression.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
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  • MakaleYalnız künye2026Scopus SJRQ2
    Influence of infill design on mechanical behavior of PLA-TPU hybrid sandwich beams

    Arikan, Volkan; Dogan, Akar; Guler, Serkan

    The purpose of this work is to analyze the mechanical behavior of hybrid sandwich beams that were printed using the Fused Deposition Modelling (FDM) technology. These beams were made of Polylactic Acid (PLA) and Thermoplastic Polyurethane (TPU) materials. Standard mechanical tests (ASTM C393 and C365) were utilized in order to assess the impact that several infill patterns (Cubic, Octet, and Trihexagonal) and infill densities (ranging from 15% to 40%) had on the flexural and compression performance of the material. According to the findings, trihexagonal patterns demonstrated improved energy absorption capabilities when subjected to compression, but octet designs offered superior flexural stiffness, particularly in hybrid constructions. According to the findings of tests conducted with hybrid constructions consisting of a TPU core and a PLA surface layer, the effect of infill patterns on component strength is directly influenced by the change in the material character, and it is possible that various materials would exhibit different manifestations of this effect. These findings offer useful information that may be used to optimize lattice geometry and hybridization procedures for the purpose of developing high-performance lightweight structures for engineering applications.

    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
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  • MakaleYalnız künye2026Scopus SJRQ3
    H-SEMI-SYMMETRY IN KÄHLER MANIFOLDS AND APPLICATIONS TO COMPLEX CONTACT MANIFOLDS

    Ünal, İnan

    Complex manifolds include different subclasses, and one of the most significant ones is the class of Kähler manifolds. These types of manifolds have valuable curvature properties that are related to almost complex structures. For this study, we focused on Kähler manifolds having semi-symmetry conditions associated with H-curvature tensors. Another important subclass is of IK-normal complex contact metric man-ifolds, which are complex manifolds with a contact structure. Since the complex structure of this type of manifold is Kähler, it has important ap-plications. In the last section, we used the results obtained for a Kähler manifold to an IK-normal complex contact metric manifold.

  • MakaleYalnız künye2026Scopus SJRQ2
    A bias-corrected partial bernstein copula approach for nonparametric regression

    Susam, Selim Orhun

    Multivariate Bernstein polynomials yield smooth, boundary–bias–free estimators for copulas and their derivatives. The classical partial Bernstein copula derivative of Janssen et al. (2016) suffers from an uncorrected first–order bias that can dominate the mean squared error (MSE) in moderate samples. We introduce a simple double–difference correction that removes the entire leading bias term while increasing the variance by a small fixed multiplicative factor only. When this bias–reduced partial derivative is plugged into the copula based regression integral, the resulting estimator achieves substantially smaller bias and uniformly lower MSE than the classical version. Analytic bias–variance expansions are provided, and a comprehensive Monte Carlo study shows up to 50% reductions in MSE across a range of Bernstein copula degrees. A real data application to the mcycle dataset further demonstrates the practical advantages of the method, with the smoothing parameters selected by least squares cross validation (LSCV).

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  • MakaleYalnız künye2026Scopus SJRQ2
    Simultaneous Leaching and Kinetics of Cu and Zn from Malachite Ore in NH3-NH4NO3 Solutions

    Bakici, Zümra; Baysar, Ahmet; Demİrkiran, Nİzamettİn

    The simultaneous leaching behavior and kinetics of copper and zinc from malachite were investigated in NH3-NH4NO3 buffer solutions at pH 9.8. The effects of solution concentration, temperature, stirring speed, average particle size, and solid to liquid ratio on the leaching rate were examined. It was observed that the leaching rate of copper and zinc increased with an increase in the solution concentration, temperature, stirring speed, and with a decrease in the solid to liquid ratio and particle size. The findings showed that copper was leached nearly completely depending on the experimental conditions while zinc was dissolved partially. While the concentration of NH3-NH4NO3, temperature, stirring speed, average particle size, solid to liquid ratio, and time were 0.38/0.11 M, 40°C, 500 rpm, 214 µm, 5/500 g/mL, and 240 min, respectively, and the amount of the leached copper and zinc was calculated to be 83.0% and 43.4%, respectively. It was determined that the leaching kinetics fit a mixed-kinetic model. The activation energy values were found to be identical for both copper and zinc leaching (16.22 kJ/mol). The process was determined to be weakly dependent on temperature, with diffusion playing a significant role in the overall leaching process.

  • MakaleYalnız künye2026Scopus SJRQ1
    Geochemical signature, detrital zircon U–Pb, and mica Ar–Ar age systematics from the Karadere Basement Unit of the İstanbul-Zonguldak Terrane (NW, Türkiye): evidence for an Avalonian-Cadomian active continental margin

    Çimen, Okay; Gücer, Mehmet Ali; Göncüoğlu, Mehmet Cemal; Akal, Cüneyt; Arslan, Mehmet; Simonetti, Antonio; Karaoğlan, Fatih

    The İstanbul-Zonguldak Terrane is located in northwest Anatolia and includes several outcrops with pre-Cambrian basement units. The Karadere Basement Unit represents the easternmost basement of this terrane and is composed of paragneiss, quartzite, and orthogneiss. The paragneiss and quartzite are cut by orthogneisses and disconformably overlain by Lower Ordovician to Middle Devonian cover units. Its pre-Cambrian to Palaeozoic tectonic evolution remains poorly understood, and therefore, this study reports whole-rock trace element signatures, detrital zircon U–Pb, and muscovite Ar–Ar age data for samples of paragneiss, quartzite, amphibolite, and orthogneiss. The whole-rock geochemical data indicate that the protoliths of the paragneiss and quartzite samples investigated here could have been derived from arc-related felsic magmatic units located in an active continental margin. The protoliths of amphibolites and orthogneiss samples are gabbro and granite, respectively, and their geochemical signatures are akin to those from continental arc igneous suites. The detrital zircon U–Pb data are characterized by predominantly Mesoproterozoic (84%) and lesser amount of Palaeoproterozoic and Neoproterozoic ages and suggest an early Tonian (youngest peak age of 915 ± 18 Ma) maximum depositional age. Moreover, zircon U–Pb dating analyses from an orthogneiss sample yielded an age of 603 ± 2 Ma, indicating the occurrence of mid-Ediacaran arc magmatism. This represents one of the oldest Ediacaran ages obtained from the metamagmatic basement rocks of the İstanbul-Zonguldak Terrane. Ar–Ar dating of muscovite from ortho- and paragneiss samples yielded ages of 533 ± 25 Ma and 530 ± 9 Ma, respectively, which are interpreted as early Cambrian cooling ages. Overall, the combined results reported here reveal that the Karadere Basement Unit is markedly different from NE African basement units but displays similarities to the basement rocks of both Avalonian and Amazonian terranes. It may have been formed and metamorphosed in an Avalonian–Cadomian active continental margin during the mid- to late Neoproterozoic and early Cambrian.

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  • MakaleYalnız künye2026Scopus SJRQ1
    Engineering Ti-Zr-Hf high-entropy alloys (HEA) with rare-earth and boron additives for microstructure-controlled mixed-field radiation shielding: Fabrication, physical, structural and experimental γ-ray & fast-n shielding properties

    Özkul, İskender; Güler, Ömer; Kavaz, E.; Kalay, Ece; Güler, Seval Hale; ALMisned, Ghada; Tekin, H.O.

    This study investigates three newly designed Ti-Zr-Hf-based high-entropy alloys such as TiZrHfGdSm (N1), TiZrHfEr (N2), and TiZrHfGdEuB (N3), with the aim of understanding how selected rare-earth and boron additions influence microstructural evolution and dual γ-ray/fast-neutron shielding performance. All alloys were synthesized by arc melting and evaluated through thermodynamic modelling, X-ray diffraction, scanning electron microscopy with elemental mapping, and mixed-field attenuation measurements. The results show that each composition forms an HCP-type solid-solution matrix with composition-dependent lattice distortion and secondary phase formation. Among the studied systems, the Er-modified alloy N2 develops the most spatially uniform elemental distribution and demonstrates the most balanced combination of γ-ray attenuation, effective atomic number, buildup behaviour, and fast-neutron removal efficiency. N1 and N3, containing multiple rare-earth elements and, in the case of N3, boron-induced borides, exhibit distinct grain features and provide valuable insights into how multi-element additions shape photon and neutron interaction pathways. Comparative examination confirms that shielding performance in these HEAs is governed by the interplay of elemental cross sections, density, and microstructural uniformity. The findings highlight Ti-Zr-Hf-RE(B) alloys as promising platforms for multifunctional radiation-shielding materials and provide a compositional framework for future optimization in nuclear, medical, and aerospace applications.

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  • MakaleYalnız künye2026Scopus SJRQ2
    Drying temperature-dependent changes in grape seed bioactives and oxidative status: integrated HPLC/GC and multivariate analysis

    Karaca Sanyürek, Nesrin

    Abstract: Drying temperature (40–80 °C) critically influences the stability of bioactive compounds in grape seeds and their functional responses. In this study, we evaluated the vitamin and phytosterol content of Boğazkere grape seeds using high-performance liquid chromatography (HPLC) and the fatty acid content using gas chromatography (GC). Antioxidant capacity was determined using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and the oxidative stress marker, malondialdehyde (MDA). Temperature-dependent and compound-specific alterations were observed: while selected vitamins and phytosterols showed distinct thermal susceptibilities, fatty acid profiles exhibited measurable remodeling. Antioxidant activity revealed non-linear dose- and temperature-dependent patterns, whereas MDA consistently decreased with increasing temperature, reflecting the reduced oxidative metabolism in dehydrated tissues. Multivariate analysis, including principal component analysis (PCA) and heatmap visualization, effectively discriminated temperature treatments and revealed correlations between compositional and functional parameters. The combined use of univariate and multivariate analyses revealed that the drying temperature reshaped not only individual bioactive compounds but also the overall biochemical profile of grape seeds. These findings establish a mechanistic link between thermal processing and bioactive stability, providing a chemical basis for optimizing grape seed valorization in food systems.

    • SDG 2 · Açlığa Son
  • MakaleYalnız künye2026Scopus SJRQ1
    Psychological well-being and aggression in handball players: examining the mediating role of exercise addiction

    Güler, Muhammed; Yeşiltepe, Akgün; Topcuoğlu, Ceyhun

    Objective: This study aimed to examine the relationship between psychological well-being and aggression among handball players and to determine whether exercise addiction mediates this relationship. Methods: A descriptive, cross-sectional, and correlational design was used. The population consisted of players competing in the Turkish Handball Leagues during the 2024–2025 season, and 442 athletes participated using a non-probability sampling method. Data were collected via an online survey including a personal information form, the Psychological Well-Being Scale, the Buss–Perry Aggression Questionnaire, and the Exercise Addiction Inventory. Results: Psychological well-being showed a significant negative correlation with aggression (r = −0.242, p < 0.001). Exercise addiction was positively associated with both psychological well-being (r = 0.212, p < 0.001) and aggression (r = 0.105, p = 0.027). Mediation analysis indicated that exercise addiction significantly and partially mediated the relationship between psychological well-being and aggression (indirect effect 95% CI: 0.0246–0.1654). The direct effect of psychological well-being on aggression remained significant (β = −0.7093, p < 0.001). Conclusion: Higher psychological well-being was associated with lower aggression among handball players, whereas exercise addiction was associated with both higher psychological well-being and higher aggression and emerged as a partial statistical mediator of this relationship. These findings may help inform future studies and preventive strategies focusing on athlete mental health and behavioral regulation. However, because of the cross-sectional design, causal inferences cannot be drawn.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
  • MakaleYalnız künye2026Scopus SJRQ2
    An Innovative Thermal Management Approach Enhanced by Thermoelectric Stations and Turbulators for Lithium-Ion Batteries

    Tuğan, Volkan; Yardımcı, Uğurcan

    The design of an effective battery thermal management system is critical to ensure the safe, efficient, and long-lasting operation of lithium-ion batteries. Excessive heat generation and temperature non-uniformity among cells in high energy density battery systems lead to performance degradation, accelerated aging, and an increased risk of thermal runaway. Although liquid-cooled systems and thermoelectric module-assisted solutions have been extensively investigated separately in the literature, studies that holistically evaluate multiple thermoelectric stations combined with an innovative flow channel design and turbulator integration remain limited. This gap constitutes a significant research need, particularly in terms of improving temperature uniformity and reducing maximum cell temperature. In this study, to address this research gap, a novel liquid-cooled battery thermal management system integrating thermoelectric coolers and turbulators within the flow channel is proposed. The thermal performance of the proposed system was systematically analyzed using computational fluid dynamics under three different configurations (conventional system, thermoelectric-assisted system, and turbulator-integrated thermoelectric-assisted system) and four different mass flow rates (0.0008, 0.0013, 0.0018, and 0.0023 kg/s). The results indicate that, at a mass flow rate of 0.0023 kg/s, the integration of thermoelectric coolers and turbulators reduces the maximum battery temperature by 8.95 K and the maximum temperature difference by 6.83 K. At the highest mass flow rate, the proposed system achieves a maximum battery temperature of 306 K and a maximum temperature difference of 4.5 K, ensuring both effective cooling performance and high temperature uniformity. Overall, the results in terms of cooling performance and temperature uniformity demonstrate that the combination of thermoelectric modules and turbulators offers significant potential for advanced battery thermal management system applications and offers an effective solution for high-energy-density systems.

    • SDG 7 · Erişilebilir ve Temiz Enerji
    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
  • MakaleYalnız künye2026Scopus SJRQ3
    Rényi holographic dark energy-inspired model and scalar field reconstruction in bianchi type III spacetime

    Korunur, Murat; Korunur, Sibel

    In this study, we consider a cosmological model based on Rényi holographic dark energy within the context of an anisotropic Bianchi type III spacetime geometry. The dark energy density is taken as a modified function of the Hubble parameter, which enables us to express the Einstein field equations in a closed dynamical system. By solving these equations, we obtain the evolution of the Hubble parameter and examine the main cosmological implications of the model. The physical behavior of the universe is discussed through the analysis of the equation-of-state parameter as well as the deceleration parameter. Our results indicate that the universe evolves from an initial decelerated expansion phase toward a late-time accelerated regime. In the asymptotic limit, the model tends to a de Sitter phase, suggesting the presence of a stable attractor configuration. In addition, we reconstruct the dark energy component in terms of different scalar field frameworks, namely quintessence, tachyon, and k-essence models. The associated scalar fields and their potentials are derived and numerically investigated. The obtained results show a coherent late-time behavior, which is in agreement with the observed accelerated expansion of the universe. The small value of the mean anisotropy parameter indicates that this evolution occurs within a quasi-isotropic Bianchi type III background.

  • MakaleYalnız künye2026Scopus SJRQ3
    A multi-parametric unit distribution via Bernstein polynomials

    Susam, Selim Orhun

    This study develops the method of constructing a multi-parametric distribution on the unit interval using Bernstein polynomials and investigates its key statistical properties. The performance of the proposed distribution’s parameter estimators was evaluated by Monte Carlo simulation under both maximum-likelihood (MLE) and minimum-distance frameworks, with the MLE approach generally yielding lower estimation error. A real data example illustrates the advantages of the construction method. The results reveal that the Bernstein distribution provides superior goodness-of-fit to the dataset compared with competing models.

  • MakaleYalnız künye2026Scopus SJRQ2
    Structural evolution and radiation shielding performance of nano-HfO2 doped lithium borotellurite glasses

    Durmus, Hasan; Kilic, G.; Ilik, E.; Kavaz, E.; Güler, Ömer; Birdogan, Selcuk; ALMisned, Ghada; Tekin, H.O.

    This study investigates the structural evolution and radiation shielding performance of lithium borotellurite glasses reinforced with nano-sized HfO2. We report on the competitive dynamics between the depolymerizing nature of the Li + network modifier and the high field strength Hf4+ nano-dopant, a relationship not previously explored in this matrix. Structural analysis via XRD and TEM reveals that the glass remains fully amorphous with homogeneously dispersed Hf rich nanodomains up to 4 mol%. A critical solubility threshold is identified at 6 mol%, where the precipitation of HfO2 and HfTe3O8 crystalline phases marks a distinct transition from an amorphous state to a glass-ceramic microstructure. Physical property measurements indicate that Hf4+ ions primarily occupy interstitial free volumes, leading to enhanced material density without significant network dilation. The incorporation of nano-HfO2 significantly augments gamma-ray attenuation efficiency, particularly in the low-energy region, by substantially increasing the effective atomic number and reducing the half value layer. Furthermore, the glasses exhibit robust fast-neutron shielding capabilities, outperforming conventional materials such as graphite and B4C. These findings establish nano-HfO2 as a potent structural and radiative modifier, providing a novel roadmap for designing high-density, multifunctional glass-ceramic shields for advanced nuclear applications.

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  • MakaleYayıncıda açık erişim2026Scopus SJRQ2
    Sperm cryopreservation of sex-reversed rainbow trout (Oncorhynchus mykiss): incorporation of amino acids and anti-oxidants to the extender media to improve the anti-oxidant system

    Kocabaş, Filiz Kutluyer; Kocabaş, Mehmet; Benzer, Fulya; Erişir, Mine

    Anti-oxidants are vital for protecting sperm and can mitigate the negative effects associated with cryopreservation. This study was conducted to evaluate the protective effects of adding anti-oxidants (vitamins and amino acids) to extender in sex-reversed rainbow trout (Oncorhynchus mykiss) sperm. The collected sperm was diluted at the ratio of 1: 5 by the extenders supplemented with different anti-oxidants including 1.00 mM of ascorbic acid and L-tryptophan, 2.00 mM of cysteine and α-tocopherol, and their combination. After dilution, the semen was aspirated into 0.50 mL straws, and the straws were placed on the tray, frozen for 10 min, and plunged into liquid nitrogen. Straws were thawed in a 30.00 ˚C water bath for 15 sec. The Sperm Class Analyzer System was used to evaluate sperm kinematics. The activity of anti-oxidant enzymes and lipid peroxidation were determined as oxidative stress indices. Our data indicated that the incorporation of anti-oxidants and amino acids increased sperm motility duration. The elevated activity of glutathione peroxidase, superoxide dismutase, and catalase in post-thaw samples indicates that the anti-oxidant system in sex-reversed rainbow trout sperm likely plays a crucial role in protecting membrane compounds from oxidation. In conclusion, the combination of 1.00 mM L-tryptophan and ascorbic acid to the extender media caused a prolonging effect in sperm motility after thawing and they have the potential to serve as effective agents for improving sperm cryosurvival.

  • MakaleYalnız künye2026Scopus SJRQ1
    Enhancing waiting time performance of clinical laboratories for pregnant patients with seasonal respiratory diseases: a simulation-based Lean Six Sigma approach

    Ortíz-Barrios, Miguel; Celani de Souza, Helder Jose; Petrillo, Antonella; Gul, Muhammet; Yücesan, Melih; Navarro-Jiménez, Eduardo; Alfaro-Saíz, Juan-José; Ariza-Ortíz, Andrés

    Purpose – Clinical laboratory performance is critical in managing seasonal respiratory diseases (SRDs); however, prolonged waiting times can lead to patient dissatisfaction and nonquality costs. This challenge is particularly acute for pregnant patients, who face increased health risks from diagnostic delays. This study aims to improve waiting times before sample collection in clinical laboratories serving pregnant patients with SRDs by integrating Lean Six Sigma (LSS) and Discrete-Event Simulation (DES). Design/methodology/approach – The proposed framework was validated in a public clinical laboratory using the DMAIC (Define–Measure–Analyze–Improve–Control) methodology. DES was embedded within the Analyze and Improve phases to model patient flow and assess improvement scenarios before implementation. Findings – The integrated LSS–DES approach resulted in a significant reduction in waiting times. During SRD peak periods, waiting time before sample collection for pregnant patients decreased from 1.01 to 0.10 h per patient. These results demonstrate the framework's effectiveness and practical usefulness for decision-makers seeking performance improvements in resource-constrained healthcare environments. Originality/value – This study enhances existing literature by integrating LSS and DES to address laboratory performance challenges associated with SRDs. The combined LSS-DES used for pregnant patients during outbreak periods is novel. The study offers contextual innovation for a vulnerable population, methodological advancement through embedding DES within the DMAIC cycle, and practical laboratory validation. The framework is particularly valuable for low- and middle-income countries (LMICs), where scalable solutions are essential.

    • SDG 3 · Sağlık ve Kaliteli Yaşam