Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Bulut, Hasan(53)
- Baskonus, Haci Mehmet(52)
- Alataş, Mevlüt(39)
- Gul, Muhammet(39)
- Serdar, Osman(38)
- Güler, Ömer(37)
- Akkurt, Nevzat(31)
- Benzer, Fulya(30)
- Sulaiman, Tukur Abdulkadir(29)
- Yucesan, Melih(29)
- Zengin, Gokhan(29)
- Kocabaş, Mehmet(28)
- Topal, Murat(26)
- Batan, Nevzat(25)
- Kök, Mediha(25)
- Ezer, Tülay(24)
- Paksoy, Mehmet Yavuz(24)
- Yildirim, Ozal(23)
- Tekin, H.O.(22)
- Utku, Anıl(22)
- ALMisned, Ghada(21)
- Ince, Muharrem(21)
- Öbek, Erdal(21)
- Erten, Fusun(20)
- Aslan, Naim(19)
- Celik, Erkan(19)
- Yildirim, Numan(19)
- Cakilcioglu, Ugur(18)
- Dal, Murat(18)
- Dal, Nursel Alp(18)
- Sahin, Kazim(18)
- Özkaynak, Fatih(18)
- Aslan, Alper(17)
- Erata, Hüseyin(17)
- Orhan, Cemal(17)
- Ergen, Burhan(16)
- Tanyol, Mehtap(16)
- Demir, Yakup(15)
- Etli, Serkan(15)
- Işık, Erdem(15)
Yayınlar
- MakaleAçık Erişim2019Scopus SJRQ3Anesthetic and sedative efficacy of peppermint (Mentha piperita) and lavender (Lavandula angustifolia) essential oils in blue dolphin cichlid (Cyrtocara moorii)
Can, Erkan; Sümer, Esma
The use of different essential oils (Eos), which are considered as a good alternative to synthetic materials, is increasing day by day in fish species. Nevertheless, studies on the anesthetic effect of peppermint Eo (Mentha piperita; MPEo) and lavender Eo (Lavandula angustifolia; LAEo) are scarce. In the present study, the effective concentrations of three anesthetic materials (MPEo, LAEo, and MS-222) were previously determined in the concentrations range of 100–400 ppm in Cyrtocara moorii juveniles (4.92 ± 1.03 g and 7.13 ± 1.22 cm) with the criteria of appropriate induction time (AIt) and ready recovery time (RRt) (Trial 1). Afterwards, four different groups were established at three different sedative concentrations (10, 20, and 30 ppm and a control group without anesthetic additive) for transporting (Trial 2). The study concluded that MPEo and LAEo can be used as anesthetic and sedative agents in tropical fish species safely. The use of 100 µL L–1 (183.5 s AIt and 227.8 s RRt) and 300 µL L–1 (109.2 s AIt and 420.0 s RRt) MPEo and LAEo, respectively, was sufficient for deep anesthesia, whereas concentrations in the range of 10 to 30 µL L–1 are recommended for fish transport.
AtıfScopus21WoS20OpenAlex22TR Dizin3
İncele - MakaleAçık Erişim2019Scopus SJRQ2Frictionless Contact Problem for a Functionally Graded Layer Loaded Through Two Rigid Punches Using Finite Element Method
Polat, A.; Kaya, Y.; Bendine, K.; Özşahin, T.Ş.
In this study, continuous contact problem in the functionally graded (FG) layer loaded with two rigid flat blocks resting on the elastic semi-infinite plane was analyzed by the finite element method. The two-dimensional numerical model of the FG layer was made with the software added to the ANSYS program. This software can be adapted to all contact problem types by making minor changes. The accuracy check of the program was performed by comparing with the analytical solution of the problem by homogeneous layer and its solution by the finite element method. So, fast and practical solutions can be obtained by the developed finite element method on many applications such as; automotive, aviation and space industry applications. The comparisons made showed that the proposed solution gave good results at acceptable levels. In the problem, it was thought that all surfaces were frictionless. The external loads P and Q were transmitted to the FG layer via two flat rigid blocks. Normal stresses between the FG layer and the elastic plane, initial separation loads, initial separation distances and contact stresses under the blocks were investigated for various dimensionless quantities.
AtıfScopus14WoS14OpenAlex11İncele - BildiriAçık Erişim2019Predicting Links in Complex Bipartite Networks Based on Strengthening Projections
Aslan, Serpil; Kaya, Mehmet
Link prediction in complex networks is a topic of high interest for many scientists that studied different areas. Many real-world complex networks have naturally bipartite structured. In this work, we proposed a link prediction method for the complex bipartite network. Recently, while link prediction in complex bipartite networks has been extensively studied, there isn't still sufficiently suitable methods for this networks. The previous works usually have some limitations. They first map the bipartite network into the unimodal projection networks. Then, they perform the link prediction using only the properties of the projection networks. However, these projection networks involve many node pairs with weak relationships when used in networks constructed from real-world data. These weak relationships lead to low probability predictions and high computation time for the algorithm. In this paper, to overcome these limitations, we first map the bipartite network into strengthening projection network model that consists of nodes that have only strong relationships. Based on this projection network, we presented the link prediction method for the complex bipartite network. We conducted extensive experiments on complex bipartite networks. The results of the experiments demonstrate that our proposed method can effectively solve the link prediction problem in complex bipartite networks.
AtıfScopus2OpenAlex2İncele - Derleme MakaleAçık Erişim2019Scopus SJRQ2A new direction in social network analysis: Online social network analysis problems and applications
Can, Umit; Alatas, B.
The use of online social networks has made significant progress in recent years as the use of the Internet has become widespread worldwide as the technological infrastructure and the use of technological products evolve. It has become more suitable to reach online social networking sites such as Facebook, Twitter, Instagram and LinkedIn via the internet and web 3.0 technologies. Thus, people have shared their views on many different topics and their emotions with other users more widely on these platforms. This means that a huge amount of data is created on platforms where millions of people connect with each other through social networks. Nevertheless, the development of computational paradigms at high speed and complexity with technological possibilities allows analysis of valuable data by means of social network analysis methods. Our goal for this paper is to present a review of novel and popular online social network analysis problems with related applications and a reference work for researchers interested in analyzing online social network data and social network problems. Unlike other individual studies we have gathered 21 online social network problems and defined them with related studies. Thus, this study is original by presenting an important source of research by explaining the problems of online social network and the studies performed in this area.
AtıfScopus172WoS113İncele - MakaleAçık Erişim2019Scopus SJRQ4α-D-glucopyranosyl-(1→2)-[6-O-(L-tryptophanyl)-β-D-fructofuranoside]
Kyeremeh, Kwaku; Kwain, Samuel; Tetevi, Gilbert Mawuli; Camas, Anil Sazak; Camas, Mustafa; Dofuor, Aboagye Kwarteng; Deng, Hai; Jaspars, Marcel
The Mycobacterium sp. BRS2A-AR2 is an endophyte of the mangrove plant Rhizophora racemosa G. Mey., which grows along the banks of the River Butre, in theWestern Region of Ghana. Chemical profiling using 1H-NMR and HRESI-LC-MS of fermentation extracts produced by the strain led to the isolation of the new compound, α-D-Glucopyranosyl-(1→2)-[6-O-(L-tryptophanyl)-β- D-fructofuranoside] or simply tortomycoglycoside (1). Compound 1 is an aminoglycoside consisting of a tryptophan moiety esterified to a disaccharide made up of β-D-fructofuranose and α-D-glucopyranose sugars. The full structure of 1 was determined using UV, IR, 1D, 2D-NMR and HRESI-LC-MS data. When tested against Trypanosoma brucei subsp. brucei, the parasite responsible for Human African Trypanosomiasis in sub-Saharan Africa, 1 (IC50 11.25 µM) was just as effective as Coptis japonica (Thunb.) Makino. (IC50 8.20 µM). The extract of Coptis japonica (Thunb.) Makino. is routinely used as laboratory standard due to its powerful antitrypanosomal activity. It is possible that, compound 1 interferes with the normal uptake and metabolism of tryptophan in the T. brucei subsp. brucei parasite.
AtıfScopus2WoS2OpenAlex2İncele - MakaleAçık Erişim2019Scopus SJRQ3Karyological investigation on five taxa of Bellevalia lapeyr. (Asparagaceae) from Turkey
Dogan, Gulden; Kiran, Yasar; Yavuz Paksoy, M.
The somatic chromosome numbers and karyotypes were examined in five Bellevalia taxa including two endemic species of B. chrisii and B. gracilis distributed in Turkey. The chromosome numbers were determined as 2n=2x=8 in all studied taxa [B. chrisii Yıldırım & B. Şahin sp. nov., B. glauca (Lindl.) Kunth., B. gracilis Feinbrun, B. longipes Post, B. sarmatica (Pallas ex Georgi) Woronow]. The karyotype formula was determined as 2m+sm+st in B. chrisii and B. longipes, 3m+st in B. glauca, B. gracilis and B. sarmatica. The findings for each of the analyzed taxa are compared with the results of previous studies.
- MakaleAçık Erişim2019Scopus SJRQ2Ultrasound as pretreatment for drying garlic slices in microwave and convective dryer
Bozkir, Hamza; Rayman Ergün, Ahsen; Tekgül, Yeliz; Baysal, Taner
The effects of ultrasound pretreatment (US) before hot air drying (HAD) and microwave drying (MWD) of garlic slices were investigated. For this aim ultrasonic bath at 30 °C for 30 min (35 kHz), microwave oven at 540 W power and tray dryer at 60 °C and with 1.0 m/s air flow rate were used to reach the final moisture content of 5%. Drying rate increased in the US + HAD and the US + MWD groups by 19.30% and 13.82% respectively in comparison with control groups. The effective moisture diffusivity (D eff ) of garlic slices were calculated from Fick’s diffusion model for the HAD, US + HAD, MWD and the US + MWD groups as 1.420 × 10 −10 , 1.826 × 10 −10 , 1.177 × 10 −8 , 1.363 × 10 −8 m 2 /s respectively. The rehydration rates increased, and bulk densities were decreased in the US + HAD and the US + MWD compared to the control groups. The color values were significantly affected after ultrasound pretreatment. Redness, and yellowness increased most in the US + HAD group.
AtıfScopus53WoS47OpenAlex58
İncele - MakaleAçık Erişim2019Scopus SJRQ4Digyaindoleacid A: 2-(1-(4-hydroxyphenyl)-3-oxobut-1-en-2-yloxy)-3-(1H-indol-3-yl)propanoic acid, a novel indole alkaloid
Kwain, Samuel; Tetevi, Gilbert Mawuli; Mensah, Thomas; Camas, Anil Sazak; Camas, Mustafa; Dofuor, Aboagye Kwarteng; Azerigyik, Faustus Akankperiwen; Deng, Hai; Jaspars, Marcel; Kyeremeh, Kwaku
Digyaindoleacid A (1) is one of the novel alkaloids produced by the Ghanaian Paenibacillus sp. DE2SH (GenBank Accession Number: MH091697) isolated from the mangrove rhizosphere soils of the Pterocarpus santalinoides tree growing in the wetlands of the Digya National Park, Brong Ahafo Region, Ghana. This compound was isolated on HPLC at tR ≈ 60 min and its structure determined by MS, 1D, and 2D-NMR data. When tested against Trypanosoma brucei subsp. brucei strain 927/4 GUTat10.1, 1 produced a half-maximal inhibitory concentration (IC50) 5.21 µM compared to the standard diminazene aceturate (IC50 = 1.86 µM). In the presence of normal mouse macrophages RAW 264.7, 1 displayed a higher selectivity towards T. brucei subsp. brucei (selectivity indices (SI) = 30.2) with low toxicity. This result is interesting given that the drug diminazene aceturate is considerably toxic and 1 is a natural product isolate. The structure of 1 incorporates the backbone of the amino acid tryptophan which is crucial in the metabolism of Trypanosoma brucei subsp. brucei strain 927/4 GUTat10.1. It is possible that 1, could interfere with the normal uptake and metabolism of tryptophan in the parasite. However, 1 (IC50 = 135.41 µM) produced weak antileishmanial activity when tested against Leishmania donovani (Laveran and Mesnil) Ross (D10).
AtıfScopus4WoS3OpenAlex4İncele - MakaleAçık Erişim2019Scopus SJRQ4Investigation of relaxation times in 5-fluorouracil and human serum albumin mixtures
Korunur, Sibel; Zengin, Bilgin; Yilmaz, Ali
Background: Human serum albumin (HSA) is often selected as a subject of any study because albumin is the most abundant protein in human blood plasma. NMR is recognized as a valuable method to determine the structure of proteins-ligand and protein-drug complexes. Objective - Aim of the study: In this study, protein drug interactions were investigated using 5-Fluorouracil anticancer drug and human serum albumin protein. Materials and methods: In this context 400 MHz NMR spectrometry was used and NMR relaxation rates in drug-albumin complex were investigated with respect to increase albumin concentration and increase in 5-Fluoro-uracil (5-FU)-albumin solution temperature. Results: The results of this study indicated that 5-FU had a weak association with albumin, and it easily dissociated from the protein to which it was attached. Conclusion: The obtained results also gave us useful information about molecular dynamics of drug-albumin interactions.
AtıfScopus4WoS3OpenAlex4TR Dizin1İncele - MakaleAçık Erişim2019Scopus SJRQ3Hybrid parliamentary optimization and big bang-big crunch algorithm for global optimization
Kiziloluk, Soner; Özer, Ahmet Bedri
Researchers have developed different metaheuristic algorithms to solve various optimization problems. The efficiency of a metaheuristic algorithm depends on the balance between exploration and exploitation. This paper presents the hybrid parliamentary optimization and big bang-big crunch (HPO-BBBC) algorithm, which is a combination of the parliamentary optimization algorithm (POA) and the big bang-big crunch (BB-BC) optimization algorithm. The intragroup competition phase of the POA is a process that searches for potential points in the search space, thereby providing an exploration mechanism. By contrast, the BB-BC algorithm has an effective exploitation mechanism. In the proposed method, steps of the BB-BC algorithm are added to the intragroup competition phase of the POA in order to improve the exploitation capabilities of the POA. Thus, the proposed method achieves a good balance between exploration and exploitation. The performance of the HPO-BBBC algorithm was tested using well-known mathematical test functions and compared with that of the POA, the BB-BC algorithm, and some other metaheuristics, namely the genetic algorithm, multiverse optimizer, crow search algorithm, dragonfly algorithm, and moth-flame optimization algorithm. The HPO-BBBC algorithm was found to achieve better optimization performance and a higher convergence speed than the above-mentioned algorithms on most benchmark problems.
AtıfScopus3WoS1OpenAlex3İncele - MakaleAçık Erişim2019Scopus SJRQ3Bioactivity-guided isolation of anti-inflammatory principles from Cistus parviflorus Lam.
Gürbüz, Perihan; Doğan, Şengül Dilem; Çelik, Gizem Nur; Bekci, Hatice; Cumaoğlu, Ahmet; Gündüz, Miyase Gözde; Paksoy, Mehmet Yavuz
Bioactivity-guided fractionation and purification of Cistus parviflorus led to the isolation of two flavan-3-ol derivatives; gallocatechin (1) and epigallocatechin (2) and two flavonoid glycosides; avicularin (3) and trans-tiliroside (4). The structures of the compounds were elucidated on the basis of NMR and ESIMS data. All compounds were isolated from C. parviflorus for the first time. Compounds 2 and exhibited antiinflammatory activity through decreasing the NOS2 and COX2 levels on LPS+IFN-γ treated RAW 264.7 cells. Molecular docking studies of avicularin, the most potent compound, were carried out in the active sites of NOS2 and COX2 to predict the most plausible binding modes and support the experimental data.
AtıfScopus7OpenAlex8TR Dizin2İncele - MakaleAçık Erişim2019Scopus SJRQ2Improvement of sperm motility of Oncorhynchus mykiss and Salvelinus fontinalis by L-tryptophan
Kocabaş, Mehmet; Kutluyer, Filiz; Ertekin, Özlem; Aksu, Önder; Başçınar, Nadir
Experiments were designed to test the influence of L-tryptophan supplementation of the extender on the sperm motility parameters and bacterial flora of brook trout (Salvelinus fontinalis) and rainbow trout (Oncorhynchus mykiss). The extender containing 0.3 M glucose in 10% Dimethyl sulfoxide (DMSO) was supplemented with 0, 0.5, 1, 2, and 4 mM L-tryptophan. Sperm samples stored for up to 12 days at 4°C for brook trout were motile while motility was not observed after six days of storage for rainbow trout. Diluted sperm samples were spread-plated onto Plate Count Agar (PCA) (Total Bacteria Count), Rose Bengal Agar (RBC) (Yeast-Mold Count), Violet Red Bile Dextrose (VRBD) (Enterobacteriaceae count) and Mannitol Salt Agar (MSA) (Micrococcus/Staphylococcus count) and counts were performed in duplicate and sampling occurred on day 0, 2, 4, 6, and 12 of cold storage. L-tryptophan supplementation of the extender yielded a positive effect, significantly prolonging sperm motility in S. fontinalis and O. mykiss compared to the control group (p < 0.05). The ideal results were obtained above a concentration of 0.5 mM for both species. Total bacteria count in fresh sperm (undiluted samples) was not detectable and not detected in sperm samples treated with different L-tryptophan concentrations. Yeast-mold, Enterobacteriaceae and Micrococcus/Staphylococcus were not detected from fresh and treated sperm brook trout and rainbow trout. On the basis of the results, L-tryptophan-based extender is useful for maintaining sperm quality in short-term storage. L-tryptophan had a negative effect on the bacterial flora. The results of the current study encourages further studies related to long-term storage and reproduction management. Abbreviations: DMSO: dimethyl sulfoxide; PCA: plate count agar; RBC: rose Bengal agar; VRBD: violet red bile dextrose; MSA: mannitol salt agar; SCA: sperm class analyzer; CFU: colony-forming unit.
AtıfScopus13WoS14OpenAlex13İncele - MakaleAçık Erişim2019Scopus SJRQ4Paenidigyamycin g: 1-acetyl-2,4-dimethyl-3-phenethyl-1H-imidazol-3-ium
Tetevi, Gilbert Mawuli; Kwain, Samuel; Mensah, Thomas; Camas, Anil Sazak; Camas, Mustafa; Dofuor, Aboagye Kwarteng; Azerigyik, Faustus Akankperiwen; Oluwabusola, Emmanuel; Deng, Hai; Jaspars, Marcel
The Ghanaian Paenibacillus sp. DE2SH (GenBank Accession Number: MH091697) is a prolific producer of potent antiparasitic alkaloids. Further detailed study of the culture broth of this strain produced the compound Paenidigyamycin G (1), which is a derivative of the known antiparasitic compound Paenidigyamycin A (2). Compound (1) was isolated on HPLC at tR ≈ 37.5 min and its structure determined by IR, UV, MS, 1D, and 2D-NMR data. Compound 1 produced weak to moderate antileishmanial and antitrypanosomal activity when tested against Leishmania donovani (Laveran and Mesnil) Ross (D10) and Trypanosoma brucei subsp. brucei strain GUTat 3.1 with IC50 = 115.41 and 28.75 µM, respectively. This result is interesting since the parent compound 2 is known to possess consistent and potent antiparasitic activity. However, 1 displayed a promising selectivity profile towards T. brucei subsp. brucei due to its relatively low toxicity against normal mouse macrophages RAW 264.7 cells (SI = 8.70). Given that compound 1 is also the main metabolite found in the hexane fraction of all extracts produced by Paenibacillus sp. DE2SH when it is co-cultured with other bacteria strains, it must possess some unique biological functions which should make it an excellent candidate for further biological activity screening in other bioassays.
AtıfScopus4WoS3OpenAlex4İncele - Derleme MakaleAçık Erişim2019Scopus SJRQ2Evaluation of X-ray tomography contrast agents: A review of production, protocols, and biological applications
Koç, Mümin Mehmet; Aslan, Naim; Kao, Alexander P.; Barber, Asa H.
X-ray computed tomography is a strong tool that finds many applications both in medical applications and in the investigation of biological and nonbiological samples. In the clinics, X-ray tomography is widely used for diagnostic purposes whose three-dimensional imaging in high resolution helps physicians to obtain detailed image of investigated regions. Researchers in biological sciences and engineering use X-ray tomography because it is a nondestructive method to assess the structure of their samples. In both medical and biological applications, visualization of soft tissues and structures requires special treatment, in which special contrast agents are used. In this detailed report, molecule-based and nanoparticle-based contrast agents used in biological applications to enhance the image quality were compiled and reported. Special contrast agent applications and protocols to enhance the contrast for the biological applications and works to develop nanoparticle contrast agents to enhance the contrast for targeted drug delivery and general imaging applications were also assessed and listed.
AtıfScopus91OpenAlex101İncele - MakaleAçık Erişim2019Scopus SJRQ1A study on the technological pedagogical contextual knowledge of science teacher candidates across different years of study
Karakaya Cirit, Didem; Canpolat, Erdal
This case study survey investigates the Technological Pedagogical Contextual Knowledge (TPCK) of Science Teacher Candidates (STC) across different years of study in the Topic of Renewable Energy (TRE). In line with the transformative model, the study treats TRE-TPCK as a new knowledge domain emerging from the interaction between content, technology, pedagogy and contextual knowledge. Participants were 36 Science Education students who were in their 1st, 2nd, 3rd and 4th years of study during the 2014–2015 academic year. Teacher candidates’ TPCK was identified through semi-structured interviews based on (1) Vignettes, (2) Anecdotes from a teacher named Zeynep and the (3) Content Presentation Technique (CPT). The data were analyzed by using the content analysis technique. The findings showed that the TRE-TPCK of teacher candidates across different years of study was at a similar and less-than-ideal level. STCs in different years of study mostly disregarded the macro and meso contexts when teaching the topic of renewable energy and were partially competent in the sub-meso, micro and sub-micro contexts. They particularly lacked technology-integrated evaluation knowledge when teaching TRE.
AtıfScopus8WoS8OpenAlex10İncele - MakaleAçık Erişim2019Scopus SJRQ2Effect of MgO,Al2O3 and FeCr2O4 on microstructure and wear resistance of Babbitt metal (Sn-Sb-Cu)
Tasgin, Yahya
In this study, the Sn-Sb-Cu alloy known as Babbitt metal and used as the coating material for the screw die surface of the journal bearings of the hydroelectric plants was reinforced with magnesium oxide (MgO), aluminium oxide (Al2O3) and ferrochromium (FeCr2O4) in order to ensure more efficient use of this alloy, formation were examined. The Babbitt prevent contact of the surface of the coating alloy with each other by acting as a separating oil layer having a 150 bar pressure. It is desired that the coating surface both resists against the high pressure applied and some part of the coating surface is asked to prevent from separating the surface of screw die as a result of high speed rotational motion and thus, damaging the shaft. Then, it was aimed to determine the wear resistance of the material as coating and the effects of the added%10 MgO,%10 Al2O3 and%10 FeCr2O4 on wear of material. As a result of the assessments carried out, it was suggested that the wear resistance of the coating would increase when the compound of Al2O3 was added into Babbitt metal. Purpose of the article used as coating material of babbitt metal, being investigated how to exert strong posture affected, under high pressure.
AtıfScopus8WoS7OpenAlex7İncele - MakaleAçık Erişim2019Scopus SJRQ3The effects of deposition potential on the optical, morphological and mechanical properties of DLC films produced by electrochemical deposition technique at low voltages
Aslan, Naim; Başman, Necati; Uzun, Orhan; Erkovan, Mustafa; Yakuphanoǧlu, Fahrettin
Diamond-like carbon (DLC) films were electrochemically deposited onto indium tin oxide (ITO) substrates using acetic acid and deionized water as electrolyte at low deposition voltages (2.4 V and 60 V). The transmittance of the films was investigated by UV spectrometry. Transmittance measurements versus wavelength revealed that the films transmit 86 % to 89 % light in visible region and band gap of the films varies between 3.87 eV and 3.89 eV. Atomic force microscopy (AFM) and scanning electron microscopy (SEM) were used for structural characterization to evaluate surface morphology of the DLC films. The grain size and the surface roughness increased for the films prepared at higher deposition potential, while their measured average height decreased. The mechanical properties (hardness H and elastic modulus Er) were determined from load-displacement curves which were obtained by using nanoindentation method. Hardness and elastic modulus of the films increased as the deposition voltage of the films increased from 2.4 V to 60 V.
AtıfScopus9OpenAlex4İncele - BildiriAçık Erişim2019Predicting Collaboration Relationships on Social Network
Aslan, Serpil; Kaya, Buket; Varol, A.; Yazici, A.; Yazici, M.A.; Varol, C.; Aygunes, G.S.; Cotur, A.
Scientific papers are mostly performed by collaboration between research groups. Researchers work in various subjects and in several research areas. Therefore, identifying a strong research group is a quite complex task. To cope with this complex task, we propose a network-based method that predicts the best appropriate collaborations for researchers in a co-authorship network. In this paper, we have constructed a weighted co-authorship network by using a real database of scientific papers. Almost all of the methods in this area use the unweighted network model. But, weighted networks are particularly important when representing the network-based properties. The constructed network consists of nodes and links which represent respectively authors and their collaborations. In these networks, if two researchers are the common authors in the same paper, they are considered connected. Typically, the link weights represent the number of papers that two authors have made collaboratively. We also use local LCP-based algorithms to calculate the betweenness and closeness of the authors in this paper. The experimental results demonstrate the success of the proposed method.
AtıfScopus3OpenAlex2İncele - Derleme MakaleAçık Erişim2019Scopus SJRQ2ANN and ANFIS Approaches to Calculate the Heating and Cooling Degree Day Values: The Case of Provinces in Turkey
Işık, Erdem; İnallı, Mustafa; Celik, Erkan
Energy analysis plays a vital role in developing an optimum and cost-effective design for the heating, ventilating and air conditioning system of a building. The values of heating degree days (HDD) and cooling degree days (CDD) are used to analyze the demand for energy for buildings. In this study, the HDD and CDD values for Turkey were calculated using estimated temperature values. An artificial neural network (ANN) and an adaptive network-based fuzzy inference system (ANFIS) were applied for the estimation of temperature values. The Levenberg–Marquardt training algorithm was used for the feedforward backpropagation of the ANN, whereas the Sugeno-type fuzzy inference system was used for the ANFIS. Meteorological data from the last 11 years were used for the proposed approaches, and these were applied to different stations (n = 50) of the Turkish State Meteorological Service. In relation to the insulated building design, base temperatures have been considered as 16 °C and 18 °C for the HDD and 22 °C and 24 °C for the CDD based on a literature review. Two novel maps were prepared for the CDD and HDD. The calculated degree days and the maps are consistent with those from the Turkish State Meteorological Service.
AtıfScopus13WoS13OpenAlex18İncele - MakaleAçık Erişim2019Scopus SJRQ1New insights into the chemical profiling, cytotoxicity and bioactivity of four Bunium species
Zengin, Gokhan; Paksoy, Mehmet Yavuz; Aumeeruddy, Muhammad Zakariyyah; Glamocilja, Jasmina; Sokovic, Marina; Diuzheva, Alina; Jekő, József; Cziáky, Zoltán; Rodrigues, Maria João; Custodio, Luisa
Bunium species have been reported to be used both as food and in traditional medicines. The scientific community has attempted to probe into the pharmacological and chemical profiles of this genus. Nonetheless, many species have not been investigated fully to date. In this study, we determined the phenolic components, antimicrobial, antioxidant, and enzyme inhibitory activities of aerial parts of four Bunium species (B. sayai, B. pinnatifolium, B. brachyactis and B. macrocarpum). Results showed that B. microcarpum and B. pinnatifolium were strong antioxidants as evidenced in the DPPH, ABTS, CUPRAC, and FRAP assays. B. brachyactis was the most effective metal chelator, and displayed high enzyme inhibition against cholinesterase, tyrosinase, amylase, glucosidase, and lipase. The four species showed varied antimicrobial activity against each microorganism. Overall, they showed high activity against P. mirabilis and E. coli (MIC and MBC <1 mg mL−1). B. brachyactis was more effective against Aspergillus versicolor compared to the standard drug ketoconazole. B. brachyactis was also more effective than both ketoconazole and bifonazole against Trichoderma viride. B. sayai was more effective than ketoconazole in inhibiting A. fumigatus. B. sayai was most non-toxic to HEK 293 (cellular viability = 117%) and HepG2 (cellular viability = 104%). The highest level of TPC was observed in B. pinnatifolium (35.94 mg GAE g−1) while B. microcarpum possessed the highest TFC (39.21 mg RE g−1). Seventy four compounds were detected in B. microcarpum, 70 in B. brachyactis, 66 in B. sayai, and 51 in B. pinnatifolium. Quinic acid, chlorogenic acid, pantothenic acid, esculin, isoquercitrin, rutin, apigenin, and scopoletin were present in all the four species. This study showed that the four Bunium species are good sources of biologically active compounds with pharmaceutical and nutraceutical potential.
AtıfScopus22OpenAlex23İncele