Sürdürülebilir Kalkınma Amaçları

Yazarlar

  • MakaleAçık Erişim2023Scopus SJRQ2
    Expression of phoenixin-14 and nesfatin-1 in the hypothalamo–pituitary–gonadal axis in the phases of the estrous cycle

    Parlak Ak, Tuba; Yaman, Mine; Bayrakdar, Ali; Bulmus, Ozgur

    Phoenixin-14 (PNX-14) and nucleobindin 2 (NUCB2)/nesfatin-1 are regulatory neuropeptides expressed in the hypothalamus. These neuropeptides can be effective in hormonal regulation of the hypothalamo–pituitary–gonadal (HPG) axis and reproductive functions. In the present study, the distribution of PNX-14 and NUCB2/nesfatin-1 in the hypothalamus, pituitary, ovary, and uterus tissues during the phases of the estrous cycle in female rats was investigated. Eighteen Wistar Albino rats determined among animals showing regular estrous cycle by vaginal smear method were divided into three groups: proestrus (Group I), estrus (Group II) and diestrus (Group III). Serum gonadotropin-releasing hormone (GnRH), plasma PNX-14, and NUCB2/nesfatin-1 concentrations were the highest, moderate, and lowest in estrus, diestrus, and proestrus phases, respectively. PNX-14 immunoreactivity in the supraoptic and arcuate nuclei of the hypothalamus and NUCB2/nesfatin-1 immunoreactivity in the paraventricular nuclei were particularly evident in the estrus phase. These neuropeptide immunoreactivities were decreased in different cells of anterior pituitary during proestrus compared with those during estrus and diestrus. PNX-14 immunoreactivity in the ovary, especially during the estrus phase, was diffuse and intense in the granulosa and luteal cells and oocytes, and it was few and weak in theca cells. In addition, NUCB2/nesfatin-1 immunoreactivity was abundant and strong in granulosa and luteal cells, theca and interstitial cells, and oocytes during estrus. In the estrus phase, PNX-14 immunoreactivity was strong in the glandular epithelial cells and stromal cells of the endometrium, also NUCB2/nesfatin-1 immunoreactivity was strong in the epithelial and glandular epithelial cells. As a result, when the estrous cycle was evaluated, it was concluded that the changes in the distribution of PNX-14 and NUCB2/nesfatin-1 at all phases were related to GnRH and that these neuropeptides showed the highest immunoreactivity especially in the HPG axis and uterus tissues of estrus rats.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus21OpenAlex22
    ScopusPubMedİncele
  • MakaleYalnız künye2023Scopus SJRQ2
    A novel electrochemical sensor for metoprolol analysis based on glutardialdehyde–zinc oxide modified boron doped diamond electrode

    Koçak, Berna; İpek, Yeliz; Keçeci, Ali

    In this study, glutardialdehyde–zinc oxide modified boron doped diamond electrode (GA2–ZnO/BDDE) was developed as a new electrochemical sensor for the rapid, sensitive and selective determination of metoprolol (MTP). By using boron doped diamond electrode (BDDE), glutardialdehyde modified boron doped diamond electrode (GA2/BDDE) and glutardialdehyde–zinc oxide modified boron doped diamond electrode (GA2–ZnO/BDDE) separately, the electrochemical behavior of MTP on the surfaces of these electrodes was determined by applying cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques. According to the results, the linear working range was 9.99 × 10−7–3.85 × 10−5 mol·L−1 and the limit of detection (LOD) was 7.53 × 10−8 mol·L−1 in pH 7 Britton–Robinson buffer solution. In addition, intraday reproducibility of peak current and peak potential were measured on the GA2–ZnO/BDDE surface and the results were calculated as 0.56 and 1 (RSD%), respectively. In order to investigate the reproducibility of GA2–ZnO/BDDE, 5 different modified electrodes were prepared with the same composition and conditions. The interday repeatability of the modified electrode was calculated as 3.13 (RSD%) and 1.05 (RSD%) for interday peak current and peak potential, respectively. The applicability of this method was confirmed by analysis of commercial drug tablets containing MTP as active ingredient. The mean recovery of the developed sensor was 95.6 % ± 1.7.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus14WoS12OpenAlex13
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2023Scopus SJRQ3
    Bioremediation of herbicide diquat dibromide from aqueous solution with white rot fungus Phanerochaete chrysosporium

    Yildirim, Numan; Ciftci, Emine; Erguven, Gokhan Onder; Durmus, Barbaros

    In this study, the fungal bioremediation of herbicide diquat dibromide (DD) by white rot fungus Phanerochaete chrysosporium was studied. After bioremediation, the reduction in toxicity of the remediated media was evaluated by Daphnia magna as a model organism. For bioremediation studies, flask-level batch experiments were performed at different DD concentrations (10, 20 and 50 ppm) under static and agitated conditions. The highest reduction rates of chemical oxygen demand and total organic carbon were determined as 85.92 (for 20 ppm DD) and 87.46% (for 10 ppm DD), respectively under agitated conditions. After bioremediation, D. magna bioassay was used for toxicity assessment during 24, 48 and 72-h periods. In current study, it was observed that P. chrysosporium has very effective bioremediation capacity for diquat dibromide. The D. magna bioassay revealed that P. chrysosporium provides effective reduction in toxicity of diquat dibromide.

    • SDG 6 · Temiz Su ve Sanitasyon
    • SDG 12 · Sorumlu Üretim ve Tüketim
  • Kitap BölümüAçık Erişim2023Scopus SJRQ4
    The Effects of Knowledge Extraction Approaches on Cryptanalysis Studies and Analysis of the Success of Chaos-Based Countermeasures

    Bürhan, Yücel; Özkaynak, Fatih

    Each new approach and scientific progress provides many advantages and innovations from theory to practice yet, its disadvantages should be evaluated comprehensively from different perspectives. In this study, the effects of knowledge extraction approaches on the cryptanalysis process have been evaluated. It is known that the secret key of the encryption algorithm can be obtained by using knowledge extraction approaches, especially with application oriented attacks such as side channel analysis. It is known that chaotic masks can be used as a countermeasure to prevent the success of these attacks. In this study, side-channel analyzes of the chaos-based substitution box structures that have been proposed in recent years have been carried out. The side channel analysis results of the existing studies in the literature have been carried out for the first time in this study. The results obtained showed that the approaches in the field of knowledge extraction should be handled more comprehensively in the cryptanalysis processes, and also pointed out that a new evaluation criterion should be analyzed for future studies for chaos-based design studies.

    AtıfScopus2OpenAlex2
    Scopusİncele
  • MakaleYalnız künye2023Scopus SJRQ1
    Analysis of the mechanical behavior and prediction of the plastic zone of a large-diameter buried gas pipeline under ground overload

    Xu, Qian; Zhong, Liqiong; Shu, Mengjie; Zou, Zhenwei; Yang, Gang; Zheng, Qiang; Chen, Xingli; Akkurt, Nevzat; Zhang, Hui; Qiang, Yujie

    Plastic failure of pipelines caused by ground overload is increasing. The one-dimensional model based on mechanical nodal parameters cannot predict the plastic failure characteristics of the three-dimensional structure of the pipeline. In order to predict the evolution of the plastic failure of the pipeline with the yield strength as the evaluation criterion, a multidimensional model is needed to consider the changes in the external loads and the changes in the mechanical properties of the pipeline along the circumferential and axial directions. In this study, a finite element calculation model for a large-diameter gas pipeline underground overload was established to investigate the law of stress change in the plastic zone. The nonlinear surface fitting method was used to establish the angle fitting model of the plastic zone and the depth fitting model of the plastic zone. The variation of the area of the plastic zone was described, and the reliability of the results was verified. In addition, the accuracy of the fitting model and the cost of the finite element calculation were evaluated. The results showed that the pipeline entered plasticity at a ground load of P = 25 MPa, and the plastic zone developed continuously in the axial and circumferential directions as the ground load increased. The angle and depth increased to 36° and 1.8 m, respectively, at P = 50 MPa. The average absolute errors for the plastic zone depth fitting model and the plastic zone angle fitting model were 6.42% and 6.64%, respectively, both of which can provide an accurate description of the plastic zone. The calculation results of the plastic zone angle fitting model could meet requirements of data processing and analysis. The plastic zone depth fitting model could be used to obtain solutions with higher accuracy, but it increases the cost of finite element simulation.

    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    AtıfScopus6OpenAlex6
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2023Scopus SJRQ1
    Effects of a Combination of Arginine Silicate Inositol Complex and a Novel Form of Biotin on Hair and Nail Growth in a Rodent Model

    Demir, Betul; Cicek, Demet; Orhan, Cemal; Er, Besir; Erten, Fusun; Tuzcu, Mehmet; Ozercan, Ibrahim Hanifi; Sahin, Nurhan; Komorowski, James; Ojalvo, Sara Perez

    The purpose of this study was to examine the effects of a combination of inositol-stabilized arginine silicate complex (ASI) and magnesium biotinate (MgB) on hair and nail growth in an animal model. Twenty-eight female Sprague–Dawley rats (8 weeks old) were randomized into one of the following groups: (i) group (control), shaved; (ii) group (ASI), shaved + ASI (4.14 mg/rat/day); (iii) group (ASI + MgB I), shaved + ASI (4.14 mg/rat/day) + MgB (48.7 μg/rat/day); and (iv) group (ASI + MgB II), shaved + ASI (4.14 mg/rat/day) + MgB (325 μg/rat/day). On day 42, compared with the control group, while hair density (p < 0.05, p < 0.01, and p < 0.0001, respectively) and anagen ratio (p < 0.01, p < 0.01, and p < 0.001) increased in the ASI, ASI + MgB I, and ASI + MgB II groups, telogen ratio decreased (p < 0.01, p < 0.01, and p < 0.001, respectively). In the molecular analysis, VEGF, HGF, and KGF-2 increased in the ASI (p < 0.01, p < 0.01, and p < 0.05, respectively), ASI + MgB I (p < 0.0001 for all), and ASI + MgB II (p < 0.0001 for all) groups when compared to the control group. FGF-2 (p < 0.01) and IGF-1 (p < 0.001) were found to be increased in the ASI + MgB I and ASI + MgB II groups. SIRT-1 and β-catenin increased in the ASI (p < 0.05 and p < 0.01), ASI + MgB I (p < 0.001 for both), and ASI + MgB II (p < 0.0001 for both) groups. Wnt-1 increased in the ASI + MgB I (p < 0.001) and ASI + MgB II (p < 0.0001) groups. In conclusion, the combination of ASI and MgB could promote hair growth by regulating IGF-1, FGF, KGF, HGF, VEGF, SIRT-1, Wnt, and β-catenin signal pathways. It was also established that ASI did not affect nail growth, whereas the MgB combination was effective using a higher dose of biotin.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus11WoS9OpenAlex11
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2023Scopus SJRQ3
    A goodness-of fit improvement based on τ-preserving transformation for semiparametric family of copulas

    Susam, Selim Orhun; Hudaverdi, Burcu

    In this paper, we study on improving the goodness-of fit for the data by using τ-preserving transform for the semiparametric family of bivariate copulas. We estimate the generator function (Formula presented.) using the Bézier polynomial function and define τ- preserving transformation on the generator function under positive quadrant dependence assumption. We investigate the performance of our methodology on real data example contained life expectancy study. The findings indicate that the model fitting is improved by using τ- preserving transformation.

    AtıfScopus3WoS3OpenAlex2
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2023Scopus SJRQ4
    Deep Learning Based Classification for Hoverflies (Diptera: Syrphidae)

    Utku, Anıl; Ayaz, Zafer; Ciftci, Derya; Ali Akcayol, M.

    Syrphidae is essential in pollinating many flowering plants and cereals and is a family with high species diversity in the order Diptera. These family species are also used in biodiversity and conservation studies. This study proposes an image-based CNN model for easy, fast, and accurate identification of Syrphidae species. Seven hundred twenty-seven hoverfly images were used to train and test the developed deep-learning model. Four hundred seventy-nine of these images were allocated to the training set and two hundred forty-eight to the test dataset. There are a total of 15 species in the dataset. With the CNN-based deep learning model developed in this study, accuracy 0.96, precision 0.97, recall 0.96, and f-measure 0.96 values were obtained for the dataset. The experimental results showed that the proposed CNN-based deep learning model had a high success rate in distinguishing the Syrphidae species.

    AtıfScopus3WoS3OpenAlex3TR Dizin1
    ScopusWeb of ScienceTR Dizinİncele
  • MakaleYalnız künye2023Scopus SJRQ3
    MOLECULAR CHARACTERIZATION OF Dittrichia viscosa (L.) GREUTER (ASTERACEAE) POPULATIONS REVEALED BY ISSR MARKERS AND CHLOROPLAST (cpDNA) trnL INTRON SEQUENCES; [MOLEKULARNA KARAKTERIZACIJA POPULACIJA Dittrichia viscosa (L.) GREUTER (ASTERACEAE) POMOĆU ISSR MARKERA I HLOROPLAST (cpDNA) trnL INTRONSKIH SEKVENCI]

    Sevindik, Emre; Bozkurt, Makbule; Yilmaz, Mehmet; Şenyüz, Ezginur; Paksoy, Mehmet Yavuz

    In this study, molecular characterization of Dittrichia viscosa (L.) Greuter populations collected from Aydın province was carried out based on ISSR technique and chloroplast DNA trnL intron sequences. 10 ISSR primers were used to determine the molecular characterization among the populations. For cpDNA trnL intron amplification, trnC and trnD primers were used. In ISSR analysis, a total of 70 bands were obtained. The polymorphism rate was determined to be approximately 94.28%. According to the ISSR analysis, the UPGMA dendrogram consisted of three groups. For cpDNA trnL intron sequences, phylogenetic analyses were obtained along with genetic distances. For populations, cpDNA trnL intron sequences were determined between 454 and 472 bases. The maximum likelihood phylogenetic tree consist of two clades. In addition, cpDNA trnL intron sequences of some species (Chrysophthalmum Pulicaria Inula Jasonia Stenachaenium Carpesium Blumea Iphiona Limbarda Rhanterium Lifago Duhaldea Chiliadenus) of Asteraceae family from NCBI with Dittrichia viscosa populations phylogenetic tree was constructed. As a result of the study, it was determined that the polymorphism rate of Dittrichia viscosa populations obtained by ISSR-PCR was higher than the results obtained from trnL intron sequences.

    AtıfScopus3WoS4
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2023Scopus SJRQ3
    Mechanical property and structural-elemental analysis of marine bivalve mollusc shells: Cerastoderma edule, Chamelea gallina, Donax trunculus, Ruditapes decussatus

    Kocabaş, Filiz Kutluyer; Kocabaş, Mehmet; Çanakçi, Aykut; Karabacak, A. Hasan

    Mussels have great annual production in the world and their shells are discarded as a waste. Shells are calcium and carbon accumulators and, formed as a consequence of calcium carbonate biomineralisation. They can be used as bio‐based composite materials in different fields. Hence, assessment of the chemical compound content and microstructure of shells is important for the prospective utility. For these reasons, structure of Cerastoderma edule, Chamelea gallina, Donax trunculus, Ruditapes decussatus shells were analyzed with X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FT-IR) and Scanning Electron Microscope-Energy Dispersive Spectroscopy (SEM-EDS). In addition, microhardness was measured in shells. Our results indicated that shells have a flake like structure with irregular grains appearance morphologically at micrometric scale. The fractions of aragonite in particular shells were assessed. EDS analysis showed that Ca, C and O were major elements of C. edule, C. gallina, D. trunculus, R. decussatus in accordance with XRD data. The lowest microhardness (2.68±0.16 GPa) was in D. trunculus while the highest microhardness (4.28±0.32 GPa) was in C. edule.

    AtıfScopus4
    Scopusİncele
  • Derleme MakaleYalnız künye2023Scopus SJRQ1
    Hydrometallurgical Roadmaps and Future Strategies for Recovery of Rare Earth Elements

    Erust, C.; Karacahan, M.K.; Uysal, T.

    Increasing demand for low carbon technologies and renewable energy sources requires our resources and economies to be circular. Many countries agree that the responsible consumption, production, and recycling of rare-earth-containing products is essential as a way to achieve the sustainable development goals also set out in the European Green Deal. Sustainable sourcing is targeted with carefully designed roadmap for cost efficient REE production from end-of-life products (EoLs) in addition to mining activities as providing primary sources. Hydrometallurgical methods, such as roasting, leaching, precipitation, crystallization, solvent extraction, and ion exchange includes fast developing, selective, eco-friendly, and cost-effective technologies especially for the extraction of REEs. This article provides an overview of primary and secondary resources and summarizes presents case scenario of studies carried out on the use of some promising methods, which could serve as an economical means for recovering REEs.

    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus46WoS46OpenAlex51
    ScopusWeb of Scienceİncele
  • MakaleYayıncıda açık erişim2023Scopus SJRQ1
    Evaluation of the effect of silica fume on the fresh, mechanical and durability properties of self-compacting concrete produced by using waste rubber as fine aggregate

    Etli, Serkan

    The supply of sand, which is obtained by disposing of natural resources for the purpose of concrete production and in accordance with production standards, is increasing rapidly and therefore its amount is rapidly depleted. A study is presented that aims to reduce the aggregate content by using this waste tire aggregate (WTA) in the construction industry, and thus, a sustainable production and conservation of nature is the basis. The water/binder ratio used in the study is kept constant as 0.39 and the binder dosage as 550 kg/m3. WTA and SF are replaced with sand and cement at the ratios of 5%, 10% and 15% by volume, and 5% and %15 b y weight, respectively. The fresh (slump flow, V-funnel, and L-box) and hardened (axial compression, splitting tensile strength, flexural tensile strength, diagonal tensile strength, and modulus of elasticity, chlorine penetration and sorptivity) properties of self-compacting concrete (SCC) mixtures produced in this way are evaluated. For the mechanical and durability tests, a total of approximately 500 SCC (100 × 100 × 500 mm: prism, 100 × 100 × 100 mm: cube and 100 × 200 mm: cylindrical) samples are produced. The mechanical experiments of SCC were carried out at 28-, 56- and 90-days age. The test results have shown that WTA substitute concrete, which can be used in terms of civil engineering in terms of all these features, has shown that it has sufficient performance.

    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus51WoS43OpenAlex55
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2023Scopus SJRQ3
    Evaluation of the spiritual care needs of risky pregnants from the perspective of the patient and the clinician: A qualitative research

    Yüksekol, Özlem Doğan; Ulucan, Mihriban; Baltacı, Nazlı; Nazik, Feyza

    Objectives: Being diagnosed with a risky pregnancy and complications developing during pregnancy cause both stress and uncertainty for women and their families, so women with risky pregnancies need spiritual care more. For this reason, this research was conducted to determine the spiritual care needs of risky pregnant women which require a multidisciplinary approach. Methods: The research is a phenomenological descriptive type of qualitative research. The study was completed with 20 participants, including 10 pregnant women who were hospitalized in the obstetrics and gynecology clinic and diagnosed with risky pregnancy, and 10 clinicians who were responsible for the care and treatment of pregnant women in the clinic. Data were collected using a semi-structured interview form. Data analysis was supported by the MaxQda 2020 Pro package program. Results: The two themes that emerged in this study are the perspectives of pregnant women and the perspectives of clinicians. Each theme is categorized as spirituality and spiritual care perceptions, spiritual care needs and experiences, and barriers to spiritual care. Conclusion: According to the findings obtained from the study, it is seen that the views of pregnant women and clinicians on spiritual care are similar. Supportive relationships and providing respectful maternal care are among the spiritual care needs of women with risky pregnancies, and these help to maintain the spiritual well-being of pregnant women.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus1WoS1OpenAlex1
    ScopusWeb of ScienceTR Dizinİncele
  • MakaleAçık Erişim2023Scopus SJRQ3
    New epiphytic bryophyte communities from Turkey; [Nove zajednice epifitskih briofita iz Turske]

    Alataş, Mevlüt; Erata, Hüseyin; Batan, Nevzat; Ezer, Tülay

    The epiphytic bryophyte vegetation of the Kümbet Plateau (Dereli-Giresun) was investigated. A total of 40 relevés taken from tree trunks in different vegetation periods of the year 2019 were analysed using multivariate analysis methods such as detrended correspondence analysis (DECORANA) and two-way indicator species analysis (TWINSPAN), and the Braun-Blanquet method was also applied. As a result, Frullanio tamarisci-Neckeretum pumilae Alataş, Ezer, Batan & Erata ass. nov. and Frullanio tamarisci-Neckeretum pumilae-isothecietosum alopecuroidis Alataş, Ezer, Batan & Erata subass. nov. were described as new syntaxa from Turkey. In addition, Ulotetum crispae -sanionietosum uncinatae was recorded for the first time from Turkey, while Ulotetum crispae was recorded for the second time from Turkey. These syntaxa were analysed in terms of their ecological and floristic aspects.

    AtıfScopus1OpenAlex1
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2023Scopus SJRQ3
    Evaluation of social factors within the circular economy concept for European countries

    Kaya, Sema Kayapinar; Ayçin, Ejder; Pamucar, Dragan

    The circular economy (CE) is a rapidly growing theme, particularly in the European Union (EU), that encourages the responsible and circular use of resources in the field of contributing to long-term development. The environmental and economic magnitude of development are frequently debated in the subject of CE whereas, social aspects have been only rarely and sporadically combined into the CE. Therefore, this study involves a multidisciplinary holistic framework of clustering methods and Multi-Criteria Decision Making (MCDM) for evaluating the CE paradigm in relation to EU countries' social growth. In terms of the social impact of CE strategies, the k-means cluster analysis was used to group the 27 EU members with similar social impact levels. Subsequently, a novel integrated CRITIC (The criteria importance through intercriteria correlation) and MEREC (Method based on the Removal Effects of Criteria) methods were employed for determining the weights of social indicators in order to balance the two weighting methods. In order to select the best country in each cluster, a novel extension of the hybrid MARCOS (Measurement of Alternatives and Ranking according to Compromise Solution) method combined with Power averaging and Heronian operator was developed. According to final solutions, Western European countries in the first cluster have the lowest unemployment and corruption rates, with the Netherlands having the best performance in this cluster. The second cluster includes countries with the lowest employment rates following university graduates between the ages of 20 and 64. Accordingly, Croatia is the best social performance in this cluster. Countries with the highest income distribution and unemployment rate are in the 3rd cluster, the best country in this group is Lithuania. Finally, the results obtained from the innovative MCDM methods have validated in order to demonstrate the proposed methodology's applicability.

    • SDG 10 · Eşitsizliklerin Azaltılması
    • SDG 12 · Sorumlu Üretim ve Tüketim
    AtıfScopus30WoS23OpenAlex42
    ScopusWeb of Scienceİncele
  • BildiriAçık Erişim2023
    Chat with ChatGPT: Access to cultural heritage with ChatGPT

    Yilmazer, Merve; Karakose, Mehmet

    Cultural heritage, in the most general sense, refers to the historical accumulations from the past to the present. Digital systems are being integrated as an alternative to physical interventions for the management, maintenance and supervision of cultural heritage sites. For these purposes, advanced intelligent systems such as machine learning and deep learning are generally used. In this study, the competence of ChatGPT, an artificial intelligence robot developed by OpenAI with a high learning rate, in the field of cultural heritage is investigated. Questions such as cultural heritage, digital cultural heritage, protection of cultural heritage, etc. were asked to ChatGPT, and the timeliness and adequacy of the answers produced in response to the questions were evaluated. In addition, a comparison of experimental studies in the literature for the preservation and cultural heritage digitalization sites is also included in this study.

    AtıfScopus6OpenAlex4
    Scopusİncele
  • MakaleAçık Erişim2023Scopus SJRQ2
    Internal deformation of continental blocks within converging plates: insights from the Ovacık Fault (Anatolia, Türkiye)

    Zabci, Cengiz; Sançar, Taylan; Tikhomirov, Dmitry; Ivy-Ochs, Susan; Vockenhuber, Christof; Friedrich, Anke M.; Yazici, Müge; Akçar, Naki

    The active tectonics of Anatolia is mostly characterized by its westward motion with respect to Eurasia between the Hellenic subduction in the west and Arabia-Eurasia continental collision in the east. Although most of the deformation is suggested to be confined along Anatolia’s boundary elements, viz. the North and East Anatolian shear zones, recent studies indicate a higher magnitude of internal strain accumulation, especially along the parallel/subparallel strike-slip faults of its central province. We present the first morphochronology-based slip rate estimate for one of these strike-slip structures, the Ovacık Fault, by using cosmogenic36Cl dating of offset fluvial deposits. At the Köseler Site (39.3643°N, 39.1688°E), two faulted risers, bounding the alluvial fan with its subplanar surface (NF1/NF1’) and the inset terrace tread (NF1/T2), are offset 19–24 and 15–22 m, respectively. The scattered surface ages and variability of 36 Cl concentrations in depth profiles suggest strong evidence for inheritance in alluvial fan and terrace deposits; thus, we used modelled depth-profile ages for both surfaces. The modelled ages 8–10 ka for NF1 and 6–8 ka for T2 yield slip-rate estimates 2.4 +0.5/–0.4 mm/a and 2.8 +0.7/–0.7 mm/a, respectively, for the upper-tread reconstruction of the NF1/NF1’and the lower-tread reconstruction of the NF1/T2. Our results together with previous slip-rate estimates for other structures show a significant internal deformation for Anatolia, especially along its subparallel strike-slip faults. These secondary faults slice Anatolia into several pieces giving rise to the formation of the Malatya-Erzincan, Cappadocian, and Central Anatolian slices, where the geometry is strongly controlled by the distribution of the Tethyan accretionary complexes.

    AtıfScopus3OpenAlex3TR Dizin1
    ScopusWeb of ScienceTR Dizinİncele
  • MakaleYalnız künye2023Scopus SJRQ2
    On the copula-based reliability of stress-strength model under bivariate stress

    Hudaverdi, Burcu; Susam, Selim Orhun

    In this paper, we consider the stress-strength reliability (Formula presented.) where the strength Y of a component lies between the dependent stress variables (Formula presented.) and (Formula presented.). We propose a copula-based approach for stress-strength reliability having bivariate stress. We obtain R for Farlie-Gumbel-Morgenstern copula with Burr III marginals. Also, we propose a Bernstein copula approximation for evaluating R under the stress-strength setup. We present empirical and maximum likelihood-based estimation procedures and compare their performances by Monte Carlo simulation. We apply the proposed approach to chemical and overt diabetes data for illustration purpose.

    AtıfScopus12WoS12OpenAlex11
    ScopusWeb of Scienceİncele
  • MakaleAçık Erişim2023Scopus SJRQ3
    Synthesis, Characterization, Antimicrobial and Time Killing Activities of New SulfaDerived Schiff Bases Coordinated with Cu(II)

    İdil, Önder; Şahal, Hakan; Canpolat, Erdal; Özkan, Mustafa

    Synthesis of three Schiff bases of 5-bromo-3-nitro salicylaldehyde containing different sulfonamide group antibiotic compounds and their Cu(II) complexes was carried out. Structures of all compounds were characterized with spectroscopic methods, including Fourier transform infrared, proton nuclear magnetic resonance, and elemental analysis. The in vitro antimicrobial activity of ligands and complexes against Gramnegative and Gram-positive bacteria and the yeast Candida albicans was evaluated. It was determined that the ligand and complexes showed outstanding antimicrobial activity against almost all of the microorganisms tested. It has been observed that the newly synthesized complexes have more antimicrobial effects than the corresponding ligands. It has been determined that the newly synthesized complexes have more antimicrobial effects than the others (E. coli, L. monocytogenes, and C. albicans), especially on Staphylococcus aureus and Pseudomonas aeruginosa.

    AtıfScopus4WoS3OpenAlex2
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2023Scopus SJRQ2
    The protective effect of arbutin against potassium bromate-induced oxidative damage in the rat brain

    Akkoyun, H. Turan; Uyar, Ahmet; Bayramoglu Akkoyun, Mahire; Bengü, Aydın Şükrü; Melek, Şule; Karagözoğlu, Fatma; Aydın, Sevinç; Ekin, Suat; Erdem, Sinem Aslan

    This study aimed to investigate the protective effects of arbutin (ARB) against brain injury induced in rats with potassium bromate (KBrO3). The rats were divided into four groups as Group 1: Control (0.9% NaCl ml/kg/day p.), Group 2: KBrO3 (100 mg/kg (gavage), Group 3: ARB (50 mg/kg/day p.), and Group 4: KBrO3 + ARB (100 mg/kg (gavage) + 50 mg/kg/day p.). At the end of the fifth day of the study, the rats in all groups were killed, and their brain tissues were collected. In the collected brain tissues, malondialdehyde (MDA), superoxide dismutase (SOD), and catalase (CAT) levels were measured, and routine histopathological examinations were made. The MDA levels in the group that was exposed to KBrO3 were significantly higher than those in the control group (p ˂ 0.001). In comparison to the KBrO3 group, the MDA levels in the KBrO3 + ARB group were significantly lower (p ˂ 0.001). It was observed that SOD and CAT enzyme activity levels were significantly lower in the KBrO3 group compared to the control group (p ˂ 0.001), while these levels were significantly higher in the KBrO3 + ARB group than in the KBrO3 group (p ˂ 0.001). Additionally, the group that was subjected to KBrO3 toxicity, as well as ARB administration, had much lower levels of histopathologic signs than the group that was subjected to KBrO3 toxicity only. Consequently, it was found that KBrO3 exposure led to injury in the brain tissues of the rats, and using ARB was effective in preventing this injury.

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