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  • MakaleAçık Erişim2026Scopus SJRQ4
    CLASSIFYING VOLUNTEERS PARTICIPATED IN SEARCH AND RESCUE ACTIVITIES: A COMPARATIVE ANALYSIS OF TOPSIS-SORT AND ORESTE-SORT METHODS

    Ozdemir, Umit; Mete, Suleyman; Gul, Muhammet

    Volunteers collaborate with professionals to provide institutional assistance in various areas; their management differs from that of professionals. To maximise volunteer productivity, categorising volunteers according to their knowledge and experience levels and distributing tasks increases volunteer retention and task efficiency. This study categorizes volunteers into four groups, fulfilling nine criteria identified through a literature review of search and rescue activities. TOPSIS-Sort and ORESTE-Sort (Optimist and Pessimist approaches) are employed in classification. Only one alternative is consistently assigned to the same class across all methods. While ORESTE-Sort offers greater flexibility and three distinct classification outcomes, it is more complex and sensitive to threshold values. TOPSIS-Sort, though simpler and producing a single classification, requires criterion weight. The Wilcoxon signed rank test is applied to evaluate the similarity between ORESTE-Sort and TOPSIS-Sort results; there are significant differences between the two methods. The study concludes by comparing the methods' applications, steps, and solution approaches, highlighting their respective advantages and disadvantages, and suggesting directions for future research.

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  • MakaleYalnız künye2026Scopus SJRQ2
    Influence of Low-SiC Content on the Tribological and Electrical Properties of Cu Composites Produced by Spark Plasma Sintering

    Çelik, Ertuğrul

    In this study, copper matrix composites reinforced with varying silicon carbide (SiC) contents (0.25, 0.5, 0.75, and 1 wt.%) were fabricated using spark plasma sintering (SPS). The effects of SiC reinforcement on the microstructure, hardness, porosity, electrical conductivity, and tribological performance were systematically investigated. Brinell hardness values increased with higher SiC content, reaching up to 76 HB for the 1 wt.% SiC composite. This improvement was accompanied by a gradual increase in porosity from 0.6 to 2.1%. Electrical conductivity decreased from 93% IACS to 66% IACS with increasing SiC content. Tribological tests revealed that the specific wear rate was significantly reduced, reaching as low as 1.1 × 10−4 mm3/N m at 15 N due to the formation of a protective tribolayer. These results demonstrate that incorporating small amounts of SiC can substantially improve hardness and wear resistance, while maintaining acceptable electrical performance, making Cu-SiC composites promising candidates for durable electrical contact applications.

    • SDG 9 · Sanayi, Yenilikçilik ve Altyapı
    AtıfScopus1WoS1OpenAlex1
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  • MakaleYalnız künye2026Scopus SJRQ1
    Effect of Ni–Co–Cr additions on the microstructural and magnetic field–induced radiation shielding behavior of Fe–Si–B alloys

    Taşgın, Yahya; Taşar, Fatih

    Fe–Si–B–based amorphous metallic glasses were synthesized via powder metallurgy and arc melting, followed by alloying with 10 wt% Ni, Co, or Cr. The alloys were examined in both as-cast and heat-treated conditions to assess the combined influence of composition, thermal relaxation, and magnetic processing on their mechanical and radiation-shielding properties. Microstructural characterizations (XRD, SEM, EDS) confirmed homogeneous alloying and the presence of Fe2B, Fe0.91Si0.09, and Ni/Co/Cr-boride phases. After alloying and heat treatment, the average Vickers hardness increased from 313 HV (base Fe-Si-B) to 480 HV. All synthesized samples were exposed to a 1 T magnetic field, and their gamma-ray attenuation behavior was subsequently evaluated using a Ba-133 source (80.99–383.85 keV). After magnetic exposure, the linear attenuation coefficient (LAC) increased by ≈ 3–4% for Co-doped alloys, ≈ 2% for Ni-doped and base Fe–Si–B alloys, and < 0.5% for Cr-doped alloys, accompanied by a corresponding reduction in half-value layer (HVL) from 1.86 cm to 1.79 cm. The fast-neutron removal cross-section (ΣR) also exhibited a modest rise (≈2%). These enhancements are attributed to field-induced microstructural relaxation, including domain alignment, internal-stress reduction, and partial free-volume collapse, which subtly modify the local electron-density distribution without altering the bulk composition. Overall, the findings demonstrate that Ni–Co–Cr alloying, combined with controlled magnetic-field exposure, offers an effective and non-destructive route to enhance both the mechanical durability and γ-ray/fast-neutron shielding performance of Fe-based amorphous alloys, highlighting their potential for magnetically tunable protective coatings and advanced smart-shielding applications. In some applications, both the magnetic properties and radiation shielding properties of the material used are important. This study investigates the effects of Ni, Co, and Cr on the magnetic properties of the Fe-Si-B alloy, while also demonstrating changes in radiation shielding properties.

    AtıfScopus1WoS1OpenAlex1
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  • MakaleYalnız künye2026Scopus SJRQ3
    Bioactive compounds in mucus and shell microstructure of the European ear snail (Radix auricularia)

    Kocabaş, Kutluyer; Kocabaş, M.; Kizak, V.; Korkmaz, B.

    Radix auricularia is a non-native and invasive freshwater snail species and it may have destructive impacts on biodiversity and ecosystem structure. In recent years, snail mucus, as a sticky substance, has garnered significant attention in the medical and cosmetic industries due to its content of numerous bioactive compounds. Despite frequently being discarded as waste due to the build-up of calcium carbonate crystals through biomineralization, shells of freshwater snail serve multiple functions in aquatic environments and have potential industrial applications. Hence, this study aims to identify bioactive compounds in the mucus and analyze the shell microstructure and mineralogy of the European ear snail (Radix auricularia). Bioactive constituents of mucus were characterized by Gas Chromatography-Mass Spectrometry (GC-FID-MS) analysis. We also conducted analyses on the organic matrix of shells from R. auricularia using X-ray diffraction (XRD) and Scanning Electron Microscope-Energy Dispersive Spectroscopy (SEM-EDS). Our results indicated that ten compounds are characterized by Eicosane (34.16%), 9-Octadecen-1-ol, (Z)-(11.86%) and N,N-Dimetylpalmitamide (5.55%) as the main components of mucus. The antioxidant potential, antifungal and anti-inflammatory properties of Eicosane was in notable quantity in the mucus. In addition, the elemental composition of shell powder comprised of carbon, aluminium, oxygen, calcium, iron, magnesium, silicium, manganese, sodium, sulphur and phosphorus. Aragonite emerged as the dominant mineralogy in the inorganic layer of their shells, as confirmed by XRD. Overall, individual compounds of mucus could be isolated and purified mucus compounds could have applications in pharmaceuticals and health sectors. The shells of R. auricularia offer potential for diverse applications and contribute to environmental sustainability as valuable biomaterials.

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  • MakaleAçık Erişim2026Scopus SJRQ2
    Change of micronucleus frequencies, antioxidant parameters and in silico in carp (Cyprinus carpio) fry exposed to ibuprofen

    Kirici, Muammer; Tüzün, Burak; Yonar, Muhammet Enis; Poustforoosh, Alireza; Mişe Yonar, Serpil; Şeker, Engin; İspir, Ünal

    Ibuprofen, a non-steroidal anti-inflammatory drug, has been detected in the aquatic environment, but little is known about its effects on fish and other aquatic organisms. This study aimed to investigate the effect of ibuprofen on micronucleus levels in erythrocytes and whole-body antioxidant parameters of carp (Cyprinus carpio) fry. Fish were exposed to immersion in two different doses of ibuprofen concentrations (50 and 250 μg/L) for 24, 48, 72 and 96 h and 14 days. No mortalities occurred in any group during the test. Abnormal behaviours such as irregular swimming, loss of balance and hanging vertically in the water were observed in some fish exposed to acute toxicity. In this study, a significant increase in the micronucleus number of red blood cells was observed throughout the study period (p < 0.05). Antioxidant parameters were measured spectrophotometrically. Results obtained showed that ibuprofen significantly increased (p < 0.05) malondialdehyde (MDA) levels, glutathione S-transferase (GST) and catalase (CAT) activities, but decreased (p < 0.05) the glutathione (GSH) levels of whole-body carp fry in a dose-dependent manner. Furthermore, ibuprofen significantly increased MDA, GST and CAT levels, but increased the GSH levels of whole-body carp fry in a time-dependent manner. These results indicate that carp fry is sensible to human pharmaceutical agents in aquatic environments. The manner and the constructed interactions between ibuprofen and two protein targets (immunoglobin and haemoglobin) were investigated using molecular docking and molecular dynamics simulation. The results indicated that ibuprofen could affect the haemoglobin activity. Finally, absorption, distribution, metabolism, excretion and toxicity analysis was performed to examine the drug potential of the studied molecules.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    AtıfScopus3OpenAlex5
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2026Scopus SJRQ1
    Radiation shielding performance of (SmEuYbLaEr)2TaO4 high-entropy oxide reinforced Cu matrix composites

    Taşgın, Yahya; Yılmaz, Demet; Kanca, M. Sait; Kök, Mediha; Yayla, Nihal; Güler, Ömer

    High-entropy oxides (HEOs) containing rare earth elements are attracting increasing interest due to their thermal stability and potential for use in radiation shielding applications. In this study, the high-entropy oxide (SmEuYbLaEr)2TaO4 was synthesized via mechanical alloying (MA) followed by calcination and incorporated into a Cu matrix at different reinforcement levels to produce volumetric composites. Structural, thermal, and microstructural analyses confirmed the successful formation of a stable HEO phase and its effective dispersion within the Cu matrix. The radiation shielding performance of the composites was experimentally evaluated over a wide range of photon energies using standard gamma-ray sources. The results showed that shielding performance depends largely on both photon energy and HEO content. Increasing the HEO concentration significantly reduced the half-value layer (HVL) while substantially increasing the mass attenuation coefficient (MAC) and radiation protection efficiency (RPE), particularly in the low- and medium-energy regions where the photoelectric effect is dominant. Among the materials studied, the Cu composite containing 20 wt% HEO exhibited the best overall shielding performance. These results demonstrate that (SmEuYbLaEr)2TaO4 is an effective additive for improving the radiation shielding capability of Cu-based composites and highlight its potential for advanced radiation protection applications.

    AtıfScopus1OpenAlex1
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  • MakaleAçık Erişim2026Scopus SJRQ2
    The Positive Effect of Antioxidants in Maintaining the Post-Cryopreserved Sperm Quality of Rainbow Trout Oncorhynchus mykiss (Walbaum, 1792)

    Handayani, Luvi S.; Rahayu, Sri R.; Razi, Nanda M.; Pane, Elya P.; Kocabas, Mehmet; Kocabas, Filiz Kutluyer; Hafizuddin, Hafizuddin; Fadli, Nur; Sulistiono, Sulistiono; Muchlisin, Zainal A.

    Rainbow trout aquaculture is challenging due to the restricted spawning seasons. Sperm cryopreservation technology can help ensure a successful spawning season, but its effectiveness is restricted by oxidative stress during freezing and thawing, which reduces the availability of male gametes. This study aimed to evaluate the effect of several types and concentrations of antioxidants on post-cryopreservation rainbow trout sperm quality. Subsequently, a factorial completely randomized design with three replications was applied, testing four types of antioxidants Ascorbic acid, Myo-inositol, Butylated hydroxytoluene (BHT), and Alpha-tocopherol at concentrations of 0, 20, 40, and 60 mM, respectively. The evaluation parameters included motility rate, sperm lifespan, and sperm motion characteristics using the Computer Assisted Sperm Analysis system. The results showed that the type and concentration of antioxidants significantly affected sperm motility and sperm lifespan (P<0.05). The treatment method carried out using 40 mM Ascorbic acid and 20 mM BHT led to the highest sperm motility of 46.67% and sperm lifespan of 34 seconds. Although both antioxidants showed similar effectiveness, BHT at a concentration of 20 mM is more recommended due to its lower toxicity and technical as well as economic efficiency considerations.

    • SDG 2 · Açlığa Son
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2026Scopus SJRQ1
    Modeling stack voltage and remaining useful life of proton exchange membrane fuel cells using deep neural networks

    Dogan, Gurkan; Imak, Andaç

    Currently, various energy conversion systems are being developed to reduce environmental impacts. Proton exchange membrane fuel cells (PEMFCs), which stand out with their high efficiency characteristics, have emerged as an important alternative. However, these advantages, along with high costs and uncertainties regarding remaining useful life (RUL) estimation, restrict their further commercialization, especially in the automotive industry. This study presents a forecasting framework using a long short-term memory (LSTM) architecture enhanced with the Bahdanau attention mechanism for predicting RUL and long-term degradation trends. The model thus exhibits a performance that can more effectively capture dependencies in time series and adaptively weight significant time steps. Furthermore, the tree-structured parzen estimator (TPE) was chosen for the appropriate selection of hyperparameters in the developed forecasting framework. The validity, stability, and performance of the proposed model under different operating conditions were examined on the FC1 and FC2 datasets. Experimental studies have shown that the proposed method is the most successful among the best methods, achieving RE metric values of 1.628 × 10−3, 0.003 × 10−1, 99.16 × 10−2, and 0.044 × 10−1 respectively in estimating the best RMSE, MAPE, R2, and RUL.

    • SDG 7 · Erişilebilir ve Temiz Enerji
    • SDG 13 · İklim Eylemi
    ScopusWeb of Scienceİncele
  • MakaleYalnız künye2026Scopus SJRQ1
    Quality Enhancement of Rhubarb (Rheum ribes L.) Jam by Ohmic Heating

    Özdede, Gizem Merve; Özakdağ, Işılay; Sevim, Esra; Karakavuk, Emrah; Sabancı, Serdal

    This study aims to comparatively investigate the production of jam from Rheum ribes L., a plant known for its functional properties, using both conventional and ohmic heating methods, and to evaluate the effects of these methods on quality parameters. Ohmic heating was applied at three different voltage gradients (25, 30, and 35 V/cm) and compared with conventional heating. In both methods, jam samples were produced until they reached a total soluble solids (TSS) content of 66%, after which total phenolic content (TPC), antioxidant activity, ascorbic acid (vitamin C), hydroxymethylfurfural (HMF), and individual phenolic compounds were analyzed. According to the results, the highest TPC (488.37 mg gallic acid equivalent [GAE]/kg), antioxidant activity (595.6 mg ascorbic acid equivalent [AAE]/kg), and vitamin C content (23.6 ppm) were obtained at 35 V/cm. In contrast, the conventional method yielded significantly lower values for these parameters and a higher HMF content (29.9 ppm). Ohmic heating enabled a much shorter processing time, reducing energy consumption by approximately sixfold and contributing to better retention of nutritional components. Additionally, higher voltage gradients resulted in improved preservation of individual phenolic compounds (such as gallic acid, catechin, and rutin). The findings indicate that, compared to the conventional method, ohmic heating offers higher efficiency, better retention of bioactive compounds, and a more sustainable production approach due to its lower energy requirement.

    • SDG 2 · Açlığa Son
    ScopusWeb of SciencePubMedİncele
  • Kitap BölümüYalnız künye2026
    The European Charter of Local Authorities and Türkiye in the Internationalization Process

    Atmaca, Yıldız; Boyali, Handan

    The European Charter of Local Authorities is an important international document adopted by the Council of Europe in 1985 with the aim of protecting the democratic and independent structure of local authorities and guaranteeing the autonomy of local authorities. This condition enables local governments to make independent decisions within their own areas of authority and responsibility, to encourage public participation in local government processes, and to have control over financial resources. Thus, local governments are no longer an extension of the central government but are becoming a structure that is closer to the public and more accountable. Türkiye, which ratified the European Charter of Local Self-Government in 1991, has tried to implement administrative reforms to strengthen the local government system. Increasing the authority and responsibilities of local governments, improving financial autonomy, and increasing citizen participation have become priority issues in the restructuring of local governments in Türkiye. However, Türkiye's reservations on some articles while accepting the charter show that it has not been able to fully implement the autonomy of local governments. For example, articles 4 and 9 of the charter limit the determination of the duties and authorities of local governments by the central government and support financial autonomy. However, the influence of the central government on local governments in Türkiye is still quite high, and the distribution of financial resources is under the control of the central authority. This is one of the most important factors limiting the autonomy of local governments. In terms of the internationalization process, Türkiye’s adoption of the European Charter of Local Self-Government has been an important step towards the country’s compliance with international democratic norms and standards. This process is also closely related to Türkiye’s European Union membership goals. This process is also closely related to Türkiye’s European Union membership goals. Türkiye aims to accelerate the harmonization process with the European Union through local government reforms and to develop the understanding of local democracy in the international arena. Türkiye’s full compliance with the principles of autonomy and participatory democracy in local governments will enable it to act in accordance with the spirit of the European Charter of Local Self-Government and to move further in the democratization process in the international arena. In this context, this study aims to examine Türkiye's internationalization process within the framework of the European Charter of Local Authorities. The contribution of the Charter to the Turkish local government system was evaluated using the literature review method.

    Scopusİncele
  • MakaleAçık Erişim2026Scopus SJRQ1
    Predictive Value of Health Literacy on Health-Promoting and Protective Behaviours in Turkish Nurses and Allied Health Workers

    Deniz Akan, Dilan; Yeşiltepe, Akgün

    Aim: This study aims to investigate the extent to which Turkish nurses and allied health workers' levels of health literacy predict health-promoting and protective behaviours. Desing: A descriptive and cross-sectional study design was used. Methods: The study was conducted with 403 Turkish nurses and allied health workers working in different regions of Türkiye between January and May 2024. JASP 0.18.3.0, Jamovi 2.3.21, and SPSS 26 and AMOS26 programs were used for data analysis. Descriptive statistics and simple and multiple regression analysis were used in the analysis of the data. Results: A positive, moderately significant relationship was found between health literacy and health-promoting and protective behaviours (r = 0.460, p < 0.001). Regression analysis results showed that health literacy explained 21.1% (R2 = 21.1) of the change in health-promoting and protective behaviours and was a significant predictor of health-promoting and protective behaviours. Patient or Public Contribution: Understanding the predictive effect of health literacy and preventive health behaviours can guide practices and policies that will improve the level of health literacy and preventive health behaviours in healthcare workers. Improving their health literacy and preventive health behaviours can help patients and the general public increase their health literacy levels and gain positive health behaviours.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    ScopusWeb of SciencePubMedİncele
  • DüzeltmeAçık Erişim2026Scopus SJRQ1
    Correction: 2D MHD Mixed Convection in a Zigzag Trapezoidal Thermal Energy Storage System Using NEPCM (Nanomaterials, (2022), 12, 19, (3270), 10.3390/nano12193270)

    Abderrahmane, Aissa; Younis, Obai; Al-Khaleel, Mohammad; Laidoudi, Houssem; Akkurt, Nevzat; Guedri, Kamel; Marzouki, Riadh

    There were errors in the original publication [1]. In Abstract and Introduction, any reference to “heat transfer (HT) irreversibility,” “fluid friction (FF) irreversibility,” or “Bejan number” is erroneous and should be removed. Any reference to “wave number” should be corrected to “zigzag number,” which is the relevant parameter in the study. The corrected Abstract and the corrected sentence in the last paragraph of the Introduction appear below, respectively. In a magnetic field, two-dimensional (2D) mixed convection is investigated within a zigzagged trapezoidal chamber. The lower side of the trapezoidal chamber is irregular, in particular, a zigzagged wall with different zigzag numbers N. The fluid particles move in the room due to the motion of the upper wall, while the porosity-enthalpy approach represents the melting process. The thermal parameters of the fluid are enhanced by what is called a nano-encapsulated phase change material (NEPCM) consisting of polyurethane as the shell and a nonadecane as the core, while water is used as the base fluid. In order to treat the governing equations, the well-known Galerkin finite element method (GFEM) is applied. In addition, the heat transfer (HT) and the dynamic behavior of flow are treated in terms of average Nusselt number and contours of streamlines. The main results show that the melt band curve of heat capacity behaves almost parabolically at smaller values of Reynolds number (Re) and larger values of Hartmann number (Ha). Moreover, minimizing the zigzag number is better in order to obtain a higher heat transfer rate. In addition, a comparative study of the heat transfer and the dynamic behavior of flow in terms of average Nusselt number and contours of streamlines has been presented. In Section 2.1. Mathematical Modeling and Equations, Paragraph 3 and Paragraph 4, the term of porosity must be added to the momentum equations. The Equations (2), (3), (8) and (9) should be updated to the following: (Formula presented.) (Formula presented.) (Formula presented.) (Formula presented.) In Section 2.1. Mathematical Modeling and Equations, Paragraph 4, Paragraph 5 and Paragraph 9, there is no cylinder inside the cavity, and any reference to a “cylinder” or “diameter D” is incorrect and should be disregarded. The pressure in Equation (6), the Reynolds Number in Equation (11) and the definition for the average Nusselt number at the zigzag wall in Equation (16) should be updated to the following: (Formula presented.) (Formula presented.) (Formula presented.) The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

    • SDG 7 · Erişilebilir ve Temiz Enerji
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2026Scopus SJRQ1
    Electrochemically assisted leaching of rare earth carbonates in non-aqueous green solvents: Solvent design, characterization, and process optimization

    Cihangir, Salih

    This study presents a systematic approach to the design, characterization, and application of non-aqueous green solvents (NAGSs) for the leaching of rare earth carbonate hydrates (RECHs). Four NAGSs based on choline chloride, ethylene glycol, and various carboxylic acids were synthesized and evaluated for their physicochemical and electrochemical properties. Among the evaluated formulations, the choline chloride–ethylene glycol–Na₂EDTA·2H₂O mixture (N1) and the chloride–levulinic acid mixture (N2) were found were found suitable for both traditional and electrochemically assisted leaching due to their optimal viscosity, conductivity, and electrochemical stability. Electrochemical assistance significantly enhanced leaching efficiency, with improvements ranging from 22 % to over 300 % for certain elements compared to conventional methods. Mechanistic investigations revealed that the application of an oxidative potential facilitates the protonation and dissolution of RECHs, likely through the generation of localized acidic environments and the formation of intermediate species. The FTIR analysis confirmed the dissolution of carbonate phases and the formation of rare earth–ligand complexes, particularly in the N1 system, where new bands associated with carboxylate and amine coordination were observed. Importantly, the proposed electrochemically assisted method can be applied to different primary or secondary sources in both aqueous and non-aqueous solutions. The results demonstrate the advantages of combining non-aqueous green solvents with electrochemical assistance as an environmentally benign alternative to conventional acid-based leaching, especially for challenging carbonate forms of rare earth elements. This work provides important guidelines for the development of sustainable hydrometallurgical processes, with future directions including solvent recyclability, selective recovery, and environmental assessment.

    AtıfScopus2WoS2
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  • MakaleAçık Erişim2026Scopus SJRQ2
    Using Decision Tree and K-Means to Improve ANFIS for Predicting Missing Flow Data in Çoruh Basin

    Acar, Ramazan

    Complete and continuous flow data provides contributions to the water resources projects appropriate design. However, both financial and technical factors prevent the regular collection of data and such a situation leads to missing data problems. Input variables are from five stations in the Çoruh Basin in the northeast province of Türkiye, and output variables are from one station. In the study, 75% (171 months of data) of the 228 months flow data between the years 1993–2011 are used in the training phase and 25% (57 months of data) in the testing phase. In the ANFIS models, Decision Tree (DT) and K-means (KM) methods are used in selecting the input variables and determining the number of membership functions. In addition, artificial neural network (ANN), multiple linear regression (MLR), and ANFIS models with randomly determined cluster numbers are also used to compare the model performance of these methods. The results show that using DT and KM methods, the ANFIS models generate more reliable results than other models. During the study, the regression coefficient (R2), weighted mean square error (WMSE), and Wilcoxon (Z) values are taken into account for reliability measure. The DT–K-means–ANFIS model achieved the highest accuracy with R2 = 0.98 and WMSE = 5.89 during the testing phase, demonstrating superior performance to the ANN and MLR models. It is shown that the most successful models can be determined in a shorter time by using DT and KM methods before generating ANFIS models.

    • SDG 6 · Temiz Su ve Sanitasyon
    AtıfScopus1WoS1OpenAlex1
    ScopusWeb of Scienceİncele
  • Derleme MakaleAçık Erişim2026Scopus SJRQ1
    Nutraceuticals in Uro-Oncology: A Structured Expert Review and Precision-Oriented Framework

    Erten, Fusun; Kalemoglu, Ecem; Kucuk, Omer; Sahin, Kazim

    Urologic malignancies (UMs), including prostate cancer (PCa), bladder cancer (BCa), renal cell carcinoma (RCC), and testicular germ cell tumors (TGCT), are governed by interconnected molecular pathways that regulate proliferation, angiogenesis, metabolism, invasion, immune escape, and treatment resistance. Key pathways include PI3K/AKT/mTOR, VEGF/VEGFR, EGFR, FGFR, c-MET, androgen receptor signaling, DNA damage response, inflammatory transcriptional programs, and regulation of the tumor microenvironment. This structured expert review evaluates mechanistic, translational, epidemiological, and clinical evidence on food- and botanical-derived nutraceuticals that may influence cancer-related signaling, redox balance, inflammation, metabolic adaptation, and host–tumor interactions. Nutraceuticals are considered investigational adjunctive exposures rather than anticancer treatments or alternatives to standard care. Relevant literature was identified through a structured, non-systematic search of PubMed/MEDLINE, Scopus, Web of Science Core Collection, and Embase from database inception to 17 June 2026, supplemented by backward and forward citation searches. Eligible evidence comprised preclinical, observational, interventional, pharmacokinetic, formulation, safety, and drug–nutraceutical interaction studies. Evidence was evaluated by cancer type, compound class, molecular context, formulation, exposure, translational maturity, and safety, and was classified into five stages: prevention signal, mechanistic plausibility, bioavailability and exposure feasibility, exposure-linked biomarker activity, and clinical benefit. An exposure–species–compartment framework was used to assess whether parent compounds and relevant metabolites reached systemic, urinary, or target-tissue concentrations compatible with the proposed effects. Findings based solely on supraphysiological concentrations of unconjugated parent compounds were considered hypothesis-generating unless supported by human exposure or tissue-distribution data. Curcumin, green tea catechins, isoflavones, carotenoids, flavonols, stilbenes, and triterpenoids affect several cancer-related pathways, primarily in experimental models. Translation to clinical practice is constrained by inconsistent formulations, limited bioavailability, inadequate target-tissue exposure data, few biomarker-linked studies, and possible interactions with anticancer therapies. PCa and BCa provide the most suitable settings for exposure-verified mechanistic studies. In RCC, safety and treatment interactions should be prioritized, whereas in TGCTs, non-interference with curative cisplatin-based therapy must be demonstrated. Future studies should use chemically defined formulations, verify clinically relevant exposure, incorporate mechanism-matched biological-response endpoints, and confirm compatibility with established treatment. Current evidence does not support nutraceuticals as treatments for urologic malignancies.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    ScopusWeb of SciencePubMedİncele
  • MakaleYalnız künye2026Scopus SJRQ1
    Sleep quality in children with epilepsy and their mothers: A cross-sectional study

    Veziroğlu, H.; Kemer, D.

    Background The aim of this study is to evaluate the sleep quality of children with epilepsy and their mothers, and to identify the factors affecting sleep quality. Methods The sample comprised 103 mothers of children with epilepsy aged 318 years. Data were collected during face-to-face interviews using the Children's Sleep Habits Questionnaire (CSHQ) and the Pittsburgh Sleep Quality Index (PSQI). The data were analyzed using one-way analysis of variance (ANOVA), the Mann-Whitney U test, and correlation analysis. Results According to PSQI, 76.7% of mothers were found to have poor sleep quality. The mean total CSHQ score was 49.99 ± 7.60, indicating clinically significant sleep problems among the children. Mothers' PSQI total scores were significantly associated with income status, number of children, duration of epilepsy, and time spent in digital environments (p < 0.05). Children's CSHQ total scores were significantly associated with age at first seizure, seizure frequency, occurrence of seizures during the last three months, presence of nocturnal seizures, number of antiepileptic drugs used, and ownership of a phone/computer (p < 0.05). Conclusion It was found that children with epilepsy experienced sleep problems related to bedtime resistance and daytime sleepiness, and that their mothers had poor sleep quality. Therefore, the development of supportive intervention programs is recommended to prevent and manage sleep problems in children with epilepsy and their mothers. Implications to practice Multidisciplinary collaboration and nurse-led interventions should be implemented to promote sleep health and improve the quality of life of children with epilepsy and their families.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    ScopusWeb of SciencePubMedİncele
  • MakaleAçık Erişim2026Scopus SJRQ2
    A Deep Learning Framework for Local Earthquake Magnitude Estimation Using Three-Component Waveforms

    Çelik, Yusuf

    This study presents a two-stage deep learning framework for accurate and generalizable estimation of local earthquake magnitudes from three-component seismic waveforms, within the context of ground-based remote sensing systems. In the first stage, phase transition boundaries are identified at the sample level to enable consistent temporal alignment of the signals. In the second stage, earthquake magnitude estimation is performed using 30 s waveform segments aligned with the early portion of the signal and enriched with spectral and statistical features. The model was initially trained on the globally diverse dataset STEAD and later fine-tuned using a subset of KOERI waveforms, and its performance was evaluated on an independent KOERI test set. The results demonstrate high prediction accuracy, with a mean absolute error of approximately 0.09 and a coefficient of determination (R2) of about 0.95, indicating strong agreement between predicted and true magnitudes. The model maintains stable performance across varying signal characteristics and geographic regions, highlighting its strong transferability. These findings suggest that seismic sensor networks can be effectively utilized as remote sensing systems for rapid and reliable earthquake characterization.

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  • MakaleYalnız künye2026Scopus SJRQ1
    Hydrogeochemical controls on chromium speciation and potential human health risks in surface waters of an ultramafic mining watershed

    Kutlu, Banu; Baydar, Tarık; Yıldırım, Vesile; Konurhan, Zekeriya

    Accurate assessment of chromium contamination in mining-influenced watersheds requires distinguishing between the environmentally contrasting Cr(III) and Cr(VI) species, yet environmental monitoring and risk assessments still rely predominantly on total chromium concentrations. This study evaluated whether chromium speciation provides additional information beyond operational total chromium for assessing chromium occurrence and potential human health risks in an ultramafic, mining-influenced watershed. Surface-water samples were collected from 28 sampling stations across the Pülümür and Ovacık regions of the Eastern Anatolia Basin (Türkiye) between March 2025 and February 2026. Chromium speciation was determined using species-specific UV–Visible spectrophotometric methods and integrated with hydrochemical characterization, multivariate statistical analyses, mineralogical investigations (XRD, SEM–EDS, and FTIR), and deterministic and empirical-bootstrap human health risk assessments. Operational total chromium, defined as the sum of separately measured Cr(III) and Cr(VI), ranged from below the detection limit to 578.13 µg L−1. For contextual screening, this calculated value exceeded World Health Organization (WHO) drinking-water guideline for total chromium at 14 stations; however, it was not an independently measured total-Cr concentration. The highest Cr(VI) concentration occurred at a localized hotspot, whereas Cr(III) predominated throughout most of the watershed. Nevertheless, Cr(VI)-based screening thresholds were exceeded at multiple stations under the assumed untreated drinking-water ingestion scenario, indicating that operational total chromium alone did not consistently identify the spatial distribution of Cr(VI)-related potential risk. Screening-level hazard quotient (HQ) estimates were higher for children than for adults; however, direct untreated consumption of the sampled surface waters was not verified. Mining-influenced stations generally exhibited higher chromium concentrations, although the relative contributions of geogenic weathering and mining-related mobilization could not be quantitatively apportioned. Overall, chromium speciation provided additional environmentally and toxicologically relevant information beyond operational total chromium for evaluating chromium mobility and screening-level potential human health risks in this ultramafic watershed.

    • SDG 3 · Sağlık ve Kaliteli Yaşam
    • SDG 6 · Temiz Su ve Sanitasyon
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  • MakaleYalnız künye2026Scopus SJRQ3
    Diverse optical soliton solutions to the generalized resonant nonlinear Schrödinger equation through an integral method

    Atas, Sibel Sehriban; Ali, Karmina K.

    This paper is concerned with the generalized resonant nonlinear Schrödinger equation with an arbitrary index, which describes ultra-short pulse propagation in optical fibers. The study uses the main integration method: the modified generalized Riccati equation mapping method, to construct and analyze combined forms of optical soliton solutions. The results are multifaceted, revealing a variety of optical soliton solutions, such as rational solutions in hyperbolic functions, combined solutions of hyperbolic and trigonometric functions, bright, singular, , kink-shaped, smooth kink, and periodic singular. Moreover, two-dimensional, three-dimensional, and contour graphs of some obtained optical soliton solutions are plotted to illustrate the importance of the generalized resonant nonlinear Schrödinger equation, using suitable values of physical parameters. Two-dimensional graphs are used to illustrate the dynamic behavior of the solutions, taking into account the impact of the nonlinear index n and the time parameter t. The obtained optical solutions are considered novel and most likely have not been reported in the literature before.

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  • MakaleAçık Erişim2026Scopus SJRQ1
    Comparative assessment of individual rare-earth oxides and high-entropy rare-earth oxides reinforcements on the structural, physical, and radiation transmission properties of Inconel 718

    Gül, Ali Oktay; Gökhan Albayrak, M.; Güler, Ömer; Özkul, İskender; Baykal, Duygu Sen; Almisned, Ghada; Tekin, H.O.

    This study addresses a fundamental materials design question for radiation-resistant superalloys: whether rare-earth (RE) oxides are more effective when incorporated individually or when introduced collectively in a high-entropy rare-earth oxide (HE-RE2O3) form. In this context, Inconel 718 (IN718) composites were reinforced with single RE2O3 phases such as Sm2O3, Tm2O3, Er2O3, Yb2O3, Eu2O3, and La2O3 at 10 wt% and with a mechanically alloyed HE-RE2O3 phase at 1-20 wt%. Structural analyses confirmed the formation of a single-phase HE-RE2O3 with a cubic bixbyite structure and its stable integration into the IN718 matrix. Gamma-ray shielding properties were systematically evaluated over a wide photon energy range. The HE-RE2O3 reinforced samples, particularly at higher loadings, exhibited consistently higher mass and linear attenuation coefficients, elevated effective atomic numbers, reduced half-value layers, and lower buildup factors compared to both the base alloy and single-oxide reinforced counterparts, demonstrating a clear collective attenuation effect. Fast neutron removal cross sections showed more moderate variations, reflecting the dominance of neutron scattering and mass-dependent interaction mechanisms rather than atomic number effects. It can be concluded that incorporating RE elements through a high-entropy oxide configuration provides a more effective and collective compositional contribution for enhancing the radiation shielding performance of IN718 than adding RE oxides individually, offering a promising pathway for advanced nuclear and radiation-relevant applications.

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