Sürdürülebilir Kalkınma Amaçları

• 4
• 1

Yazarlar

• Mişe Yonar, Serpil(2)
• Pala, Ayşegül(2)
• Yonar, M. Enis(2)
• Danabas, Durali(1)
• Eroğlu, Mücahit(1)
• Gulec, Azime Kucukgul(1)
• Kaplan, Olcay(1)
• Pala, A.(1)
• Pala, Aysegul(1)
• Saglam, Naim(1)
• Sakin, Fatih(1)
• Sağlam, Naim(1)
• Silici, Sibel(1)
• Yildirim, Numan(1)
• Yildirim, Nuran Cikcikoglu(1)
• Yonar, M. E.(1)
• Yonar, Muhammet Enis(1)
• Yonar, S. Mise(1)
• Yonar, Serpil Mise(1)
• Yöntürk, Y.(1)
• İspir, Ünal(1)

• MakaleAçık Erişim2026Scopus SJRQ2/r/munzur/898
  Cadmium-induced changes in haemato-immunological, oxidative stress and antioxidant parameters of Cyprinus carpio: Protective role of curcumin

  Pala, Ayşegül; Eroğlu, Mücahit; Mişe Yonar, Serpil; İspir, Ünal; Yonar, Muhammet Enis

  This study examined the adverse effects of sublethal concentrations of cadmium (Cd) and the potential of curcumin (CUR) to mitigate Cd-induced toxicity. We administered 1.5 and 3 mg/L of Cd and 100 mg/kg of CUR to fish (Cyprinus carpio) separately and in combination over 14 days. At the end of the experiments, various haematological and immunological parameters, oxidative stress levels and antioxidant parameters of fish were measured, and the differences between the groups were evaluated. Simultaneous CUR treatment with Cd reversed the changes in haematological parameters in fish, increased immune responses, reduced oxidative stress and normalized the impaired antioxidant enzyme activities. In summary, our study showed that dietary supplementation with CUR may be an effective strategy to reduce the toxic effects of Cd in carp.

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  İncele
• MakaleAçık Erişim2020Scopus SJRQ1/r/munzur/3670
  Effect of trichlorfon on some haematological and biochemical changes in Cyprinus carpio: The ameliorative effect of lycopene

  Mişe Yonar, Serpil; Yonar, M. Enis; Pala, Ayşegül; Sağlam, Naim; Sakin, Fatih

  Trichlorfon (TCF) is an antiparasitic agent used in aquaculture to treat external parasites and it belongs to the chemical class of organophosphates. This study was conducted to investigate the ameliorating effects of lycopene on TCF-induced toxicity in carp by evaluating haematological parameters and oxidant/antioxidant status. Fish were randomly divided into seven experimental groups. These groups were arranged as follows: control (no treatment) group, corn oil group, lycopene (10 mg kg−1) group, TCF-I (11 mg L−1) group, TCF-I (11 mg L−1) plus lycopene (10 mg kg−1) group, TCF-II (22 mg L−1) group and TCF-II (22 mg L−1) plus lycopene (10 mg kg−1) group. At the end of 14 days administration, blood and tissue (liver, kidney, and gill) samples were collected. Haematological changes [red blood cell (RBC) and white blood cell (WBC) count, haemoglobin (Hb) concentration, haematocrit (Ht) level, and erythrocyte indices: mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), and mean corpuscular haemoglobin concentration (MCHC)] were determined in the blood samples, while antioxidant parameters [(malondialdehyde (MDA) and reduced glutathione (GSH) levels and superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities] were evaluated in the liver, kidney and gill samples. The results demonstrated that all the haematological parameters were significantly decreased in the TCF-I and TCF-II groups when compared to the control group. Notable increases in the tissue MDA levels were observed in the TCF-treated groups. In contrast, significant decreases were observed in the tissue SOD, CAT and GSH-Px activities and GSH levels in the TCF-I and TCF-II groups. However, simultaneous treatment with lycopene provided a marked normalisation of the haematological and oxidant/antioxidant parameters compared with the TCF-I and TCF-II groups. The findings show that dietary lycopene supplementation might be helpful in abrogation of TCF toxicity by changing haematological conditions and antioxidant status in fish.

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  AtıfScopus34·WoS28·OpenAlex31

  İncele
• MakaleAçık Erişim2015Scopus SJRQ1/r/munzur/3985
  Trichlorfon-induced haematological and biochemical changes in Cyprinus carpio: ameliorative effect of propolis

  Yonar, M. Enis; Yonar, Serpil Mise; Pala, Aysegul; Silici, Sibel; Saglam, Naim

  Trichlorfon is among the most commonly used products to treat fish parasites in aquaculture. We investigated the effectiveness of propolis in alleviating the toxicity of trichlorfon on haematological and oxidant/antioxidant parameters in carp Cyprinus carpio. Fish were exposed to sublethal concentrations (11 and 22 mg l(-1)) of trichlorfon, and propolis (10 mg kg(-1) of fish weight) was simultaneously administered. At the end of 14 d administration, blood and tissue (liver, kidney, gill) samples were collected. Haematological changes (red and white blood cell count, haemoglobin concentration, haematocrit level and erythrocyte indices: mean corpuscular volume, mean corpuscular haemoglobin and mean corpuscular haemoglobin concentration) were determined in the blood samples, while antioxidant parameters (malondialdehyde and reduced glutathione levels and superoxide dismutase, catalase and glutathione peroxidase activities) were evaluated in the liver, kidney and gill samples. Trichlorfon led to negative alterations in the haematological and antioxidant parameters investigated. The administration of propolis alleviated this effect and suggests that fish treated with trichlorfon improve their physiological status when fed a propolis-supplemented diet.

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  AtıfWoS46·OpenAlex56

  İncele
• MakaleYalnız künye2014Scopus SJRQ1/r/munzur/4792
  Effect of ellagic acid on some haematological, immunological and antioxidant parameters of rainbow trout (Oncorhynchus mykiss)

  Yonar, S. Mise; Yonar, M. E.; Yöntürk, Y.; Pala, A.

  In this study, effect of ellagic acid on some haematological, immunological and antioxidant parameters in the blood and various tissues of rainbow trout (Oncorhynchus mykiss) were examined. Four groups of rainbow trout were fed experimental diets containing either no ellagic acid (control) or supplemented with ellagic acid at 50mg/kg diet (EA-50), 100mg/kg diet (EA-100) or 150mg/kg diet (EA-150) for 21days. Samples of the blood and tissue (liver, kidney and spleen) were collected at the end of the experiment and analysed for their haematological profile (the red blood cell count, the haemoglobin concentration and the haematocrit level), immune response (the white blood cell count, the oxidative radical production (NBT activity), the total plasma protein and total immunoglobulin level) and oxidant/antioxidant status (the malondialdehyde level, the superoxide dismutase, catalase and glutathione peroxidase activity as well as the reduced glutathione concentration). The findings of this study demonstrated that ellagic acid had a positive effect on the haematological parameters, the immune response and the antioxidant enzyme activities of the fish.

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  AtıfWoS35·OpenAlex37

  İncele
• MakaleYalnız künye2010Scopus SJRQ3/r/munzur/4771
  An Investigation on Some Haematological and Biochemical Parameters in Capoeta trutta (Heckel 1843) from Munzur River (Tunceli, Turkey)

  Danabas, Durali; Yildirim, Nuran Cikcikoglu; Gulec, Azime Kucukgul; Yildirim, Numan; Kaplan, Olcay

  Fishes are largly used for the assessment of aquatic environment quality and are accepted as bioindicators of environmental pollution. This study evaluated haematological and biochemical responses of Capoeta trutta captured in Munzur River, Tunceli, Turkey. Blood and biochemical parameters (Sodium (Na), Potassium (K), Calcium (Ca), Phosphorus (P), Chlorine (Cl) and Iron (Fe)) were determined. The values of Red Blood Cell (RBC) Haemoglobin (Hb), Haemotocrit (Ht), Haemoglobin Concentration (MCHC), Platelet Count (PLT), Mean Platelet Volume (MPV), Plateletcrit (PCT), Platelet Distribution Width (PDW) from examined haematological parameters were found as 0.67+/-0.09 10(12) L(-1), 13.5+/-0.90 g dL(-1), 14.78+/-0.19%, 218.40+/-4.29 fL, 194.75+/-15.36 pg 108.52+/-1.09 g dL(-1), 34.12+/-5.89 10(9)L(-1), 11.92+/-1.65 fL, 0.061+/-0.01% and 19.77+/-1.71 fL, respectively. The values of Fe, Cl, P, Ca, K and Na from examined biochemical parameters were determined as 91.75+/-28.27 g dL(-1), 92.00+/-4.02 mmol L(-1), 13.20+/-1.26mg dL(-1), 11.65+/-0.74 mmol L(-1), 1.30+/-0.21 mmol L(-1) and 132.5+/-3.90 mg dL(-1) respectively. Observation of blood parameters allows the most rapid detection of changes in fish after the exposure to xenobiotics. It can conclude that hematological and biochemical parameters could be ranked as possible biomarkers of pollution.

  AtıfWoS5

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