Sürdürülebilir Kalkınma Amaçları
Yazarlar
- Aydın, Sevinç(3)
- Çakır, Atilla(3)
- Aydin, Sevinc(2)
- Cikcikoglu Yildirim, Nuran(2)
- Erman, Orhan(2)
- Karaca Sanyürek, Nesrin(2)
- Kaya, Tubay(2)
- Ogedey, Aysenur(2)
- Serdar, Osman(2)
- Tatar, Sule(2)
- Yildirim, Numan(2)
- Yılmaz, Ökkeş(2)
- Akbaba, Emel(1)
- Akbulut, Gulcin Beker(1)
- Beker Akbulut, Gülcin(1)
- Emir Çoban, Özlem(1)
- Erişir, Figen Erdem(1)
- Erman, Fazilet(1)
- Gürel Inanlı, Ayşe(1)
- Karaton Kuzgun, Nermin(1)
- Obek, Erdal(1)
- Odabaşioğlu, Mehmet İlhan(1)
- Odabaşıoğlu, Mehmet İlhan(1)
- Sahilli, Yeliz Cakir(1)
- Sanyürek, Nesrin Karaca(1)
- Tatar, Sule Yuksel(1)
- Torgut, Gulben(1)
- Torğut, Gülben(1)
- Yildirim, Nuran Cikcikoglu(1)
- Yilmaz, Okkes(1)
- Özpolat, Emine(1)
- İşlek, Fırat(1)
Yayınlar
- MakaleAçık Erişim2026Scopus SJRQ1Comprehensive Analysis of Phytochemical Compounds in Seeds of Indigenous Grape Varieties Cultivated in Southeastern Anatolia: Fatty Acids, Tocopherols, Phytosterols, Vitamins, and Antioxidant Properties
Odabaşioğlu, Mehmet İlhan; Çakır, Atilla; Karaca Sanyürek, Nesrin; İşlek, Fırat
Aim: In this study, the phytochemical composition of the seeds of twelve different local grape (Vitis vinifera L.) varieties traditionally cultivated in the Southeastern Anatolia Region (Diyarbakır, Türkiye) was investigated using a holistic approach. The main objective of the study was to evaluate the associations of the effects of berry skin colour, the ripening stage and utilization type on the fatty acid profile, tocopherol and phytosterol contents, vitamin K and D levels, antioxidant capacity (DPPH) and lipid peroxidation (MDA) of grape seeds. Method: The seeds of grape varieties belonging to four different colour groups, grown on their own roots, were harvested during the 2017 growing season and analysed. Fatty acid composition was determined by gas chromatography (GC), vitamin and phytosterol contents by HPLC-UV, MDA content by the thiobarbituric acid reactive substance (TBARS) method, and antioxidant capacity by the DPPH radical scavenging assay. Findings: Linoleic acid was identified as the predominant fatty acid in all varieties (53.68–67.06%), followed by oleic acid (13.80–27.32%). α-Tocopherol was identified as the predominant tocopherol form (1.597–4.703 mg kg−1), whilst β-sitosterol was the phytosterol component present at the highest level (915.67–3340.42 µg g−1). Statistically significant varietal differences were detected for most measured phytochemical parameters. Group-wise differences associated with berry skin colour and ripening stage were observed for selected traits. Overall, varietal differences appeared to be more pronounced than those associated with berry skin colour or ripening stage. It was observed that the differences in phytochemical composition between the various commercial classifications of grapes were very limited. Result: The findings reveal that the seeds of the local grape varieties studied exhibit a rich phytochemical profile and represent an important source of bioactive compounds that could be utilised, particularly in the functional food, nutraceutical and cosmetics industries. The ‘Tahannebi’ variety stood out as the one with the highest values across many parameters. Differences observed among samples of the same cultivar collected from different vineyards suggest that vineyard-specific conditions may contribute to variation in selected phytochemical traits. Future multi-year and multi-location studies are needed to confirm the stability of these phytochemical profiles and to further clarify genotype × environment interactions.
- MakaleYayıncıda açık erişim2023Scopus SJRQ3Vitamin content and MDA levels of certain white grape varieties from different altitudes in Turkey
Akbaba, Emel; Aydın, Sevinç; Sanyürek, Nesrin Karaca; Çakır, Atilla; Erişir, Figen Erdem
Grapevine (Vitis vinifera L.) is regarded as one of the world’s most important fruit crops in terms of acreage and commercial worth. Grapes are used to make not only wine but also fresh fruit, dried fruit, and juice. The quality of grapes or wine is significantly affected by environmental factors such as altitude, soil type, and climate. In this study, the 5 white grape varieties (Ağın beyazı, Tahannebi, Kabarcık, Şilfoni, and Besni) grown at different altitudes (800 m, 1000 m and 1200 m) in Turkey were investigated for their vitamin, and phytosterol concentrations as well as lipid peroxidation content. Şilfoni grape harvested at 800 m was found to possess the lowest lipid peroxidation content. High altitudes, were found to reduce lipid peroxidation contents in the Ağın beyazı, Tahannebi, and Kabarcık strains. The highest stigmasterol (98.34 μg/g), and beta-sitosterol (86.90 μg/g) concentrations were found within Şilfoni grape variety harvested at 800 m. The highest vitamin D-2 and D-3 levels were found in Ağın beyazı (1.39 μg/g) and Kabarcık (4.13 μg/g) grape varieties, both harvested at 1200 m. Kabarcık grape, however, revealed the highest concentrations of R-tocopherol (63.09 μg/g) and alpha-tocopherol (24.13 μg/g) at 1200 m within the samples. The highest vitamin K-2 level was determined within the Tahannebi grape (15.44 μg/g) from 1200 m. It was observed that the vitamin and phytosterol concentrations of white grape varieties tended to increase, while the lipid peroxidation values tended to decrease at high altitudes, especially at 1200 m. This study also exhibited a strong relationship among Vitamin D3, R-tocopherol, and alpha-tocopherol in the studied white grape cultivars.
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İncele - MakaleYalnız künye2023Scopus SJRQ3Comprehensive Evaluation of the Relationships Between Grape Skin Color/Ripening Time and Antioxidative Capacity, Some Phytochemicals, and Fatty Acid Compositions of Their Seeds
Çakır, Atilla; Odabaşıoğlu, Mehmet İlhan; Karaca Sanyürek, Nesrin; Aydın, Sevinç
It has been proven that grapes, which are widely cultivated around the world, have positive health effects. However, the phytochemical composition of lesser-known local varieties of Vitis vinifera L., which has a very wide range of varieties, is still being studied. The aim of this study was to determine the effects of skin color and ripening time on the phytochemical compositions of grape seeds. As a plant material local grape varieties cultivated in Southeastern Anatolia (Turkey) were used. The results showed that grape skin color has an effect on vitamin K1, vitamin K2, vitamin D3, δ‑tocopherol, stigmasterol, ergosterol, myristic acid, oleic acid, trans-elaidic acid, and the monounsaturated fatty acid (MUFA) and saturated fatty acid (SFA) contents of seeds. The seeds of grape varieties with colored skins were richer in K2, D3, stigmasterol, oleic acid, trans-elaidic acid, and MUFAs, while the seeds of grape varieties with white skins were richer in K1, δ‑tocopherol, ergosterol, and SFAs. The ripening time of the grapes was found to have a partial effect on the fatty acid compositions of the seeds, but without any effect on linoleic acid contents. As the ripening time was delayed, there was an increase in oleic acid and MUFA contents of the seeds, while there was a decrease in SFA contents. In general, increased vitamin K1 contents of the seeds were parallel to decreases in vitamins K2, D2, and D3, as well as α‑tocopherol content and antioxidant activity. The seeds of grape varieties that have colored skins were found to have more suitable compound compositions for use in the production of functional foods that support human and animal health. In addition, it was concluded that grape berries that ripen late may be more favorable for grapeseed oil production.
AtıfScopus3WoS4OpenAlex3İncele - MakaleYalnız künye2021ANTIOXIDANT ACTIVITIES AND SOME BIOCHEMICAL CONTENTS OF THE SEEDS OF THE OKUZGOZU AND BOGAZKERE (Vitis vinifera L.) GRAPE VARIETIES GROWN IN TURKEY
Aydin, Sevinc
The Vitis vinifera L. grape species is a fruit that is the most prevalently grown in the whole world and has economic significance. It is known that, due to its climate conditions, Turkey has rich resources in terms of Vitis vinifera L. With this study, we aimed to determine the phenolic, vitamin and fatty acid contents of the Okuzgozu and Bogazkere varieties of Vitis vinifera L. and see the effects of these contents on antioxidant activity. Fatty acids in the lipid extract were analyzed by gas chromatography after conversion into methyl esters. For flavonoid and vitamin analyses, a high-performance liquid chromatography device (HPLC-UV. Shimadzu) was used. Antioxidant activity was determined by Radical Scavenging Activity (DPPH) and Lipid Peroxidation (MDA) experiments, As a result of the study, some saturated and unsaturated fatty acid, phenolic compound and vitamin contents of the two varieties were obtained. It was observed that the amounts of unsaturated fatty acids, whose effects on antioxidant activity are known, in the Okuzgozu variety were significantly higher than those in the Bogazkere variety. The results on phenolic and vitamin compounds revealed higher amounts in the Okuzgozu variety in comparison to Bogazkere as in the case of fatty acids. The finding that these contents and antioxidant activity were in proportion suggested that the antioxidant effect of the Okuzgozu variety is higher. If the substances that provide this effect are correctly isolated from the plant, they may be used beneficially in both the food and pharmaceutical sectors.
- MakaleAçık Erişim2021Scopus SJRQ3The protective effects of lupine (Lupinus albus) fruit extract against to destructive effects of hyperglycemia in type I diabetic rats
Aydın, Sevinç; Kaya, Tubay; Erman, Orhan; Yılmaz, Ökkeş
Background: Lupinus albus is a member of the Fabaceae family. As a natural or cultivat-ed plant, Lupinus albus is distributed in Europe, the Balkans and Turkey, especially in Marmara and Aegean regions. The lupine is a nutritious and protective plant against diabetes. Objective: In the present study, the effects of Lupinus albus fruits on malondialdehyde (MDA), reduced glutathione (GSH), total protein, ADEK vitamins, and cholesterol values, which are the indi-cators of oxidative damage and antioxidant defense. In this regard, muscle, liver, renal, and brain tissues of STZ-induced type I diabetes rats were studied. Methods: The analyzes of ADEK vitamins and cholesterol levels in tissues were performed via Shimadzu HPLC device. The lipid peroxidation levels were measured at 532 nm in spectrophotome-ter. Determination of GSH was read at 412 nm against blank, and for the total protein levels Lowry method was applied. Results: According to the results obtained, it was determined that among the rats with induced type I diabetes, the group applied lupine fruit extract was found to have increased GSH level and decreased MDA levels in all the tissues. The protein values were increased in liver tissues but decreased in the other tissues. The level of vitamins was significantly increased in almost all the tissues in the diabetic group. Conclusion: In the present study, it was shown that the lupine reduced the devastating effects of type I diabetes by decreasing the fasting blood glucose and lipid peroxidation values and increasing the glutathione level in comparison to the diabetic group.
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İncele - MakaleYalnız künye2020Scopus SJRQ4Biochemical responses of some (Helianthus annuus L.) cultivars to the interaction effects of biodegradable polymer and salt stress
Akbulut, Gulcin Beker; Torgut, Gulben
Salt stress is one of the most important environmental factor limiting plant growth and causing serious agricultural problems in the world. Biodegradable poly(ethylene oxide)-co-(ε-caprolactone) poly(EO-co-ε-CL) copolymer synthesized by ring-opening polymerization (ROP) have been used to reduce this negative effect. For the characterization of this copolymer, the Fourier Transform Infrared (FT-IR), Proton Nuclear Magnetic Resonance (1H-NMR), Differential Scanning Calorimetry (DSC) and Thermogravimetric Analysis (TGA) techniques were used. To investigate the impact of copolymer and salt (200 mM NaCl) singly and in combination, on two different sunflowers (Helianthus annuus L. cv. 'Düet' and Helianthus annuus L. cv. 'Meteor') a series of experiments were established. In the seedlings grown for 21 days, differences in some metabolic parameters such as chlorophyll-a (Chl-a), chlorophyll-b (Chl-b), carotenoids (Car), total chlorophyll (Chl), total carbohydrate content, and malondialdehyde (MDA) content were examined. According to the result of our study, after the application of NaCl and poly(EO-co-ε-CL), significant changes were observed in the studied biochemical parameters. It was observed that the copolymer in both species had a healing effect against salt stress. Application of 200 mM NaCl caused an increase in MDA of both genotype, particularly in 'Meteor'. Higher Chl-a, Chl-b, total Chl, and Car contents were observed in 'Meteor' as compared to that in 'Düet' under saline conditions. Total carbohydrate content decreased with increasing salt stress in both cultivars.
AtıfScopus1İncele - MakaleYalnız künye2020Scopus SJRQ4The protective effects of golden berry (Physalis peruviana L.) extract against to the oxidative and destructive effects of type i diabetes in rats
Erman, Fazilet; Kaya, Tubay; Aydin, Sevinc; Erman, Orhan; Yilmaz, Okkes
Type I diabetes is known as insulin-dependent diabetes mellitus, and the most important factor playing role in its formation is the genetic predispo- sition. Physalis peruviana L. (Goldenberry) is a plant, which has strong antioxidant properties, from Solanaceae family and, because of its fructose con- tent, plays regulatory role in blood glucose level of diabetics. In this study, it has been investigated the effects of goldenberry on the malondialdehyde (MDA), reduced glutathione (GSH), total protein, vitamins A, D, E, and K, and cholesterol levels which are the indicators of antioxidant defense and the oxidative damages in serum, muscle, kidney, liver and brain tissues of the rats, on which type I diabetes was induced by STZ. According to the obtained results, among the rats with STZ-induced type I diabetes, it was ob- served that the level of glutathione (GSH) increased and the level of malondialdehyde (MDA) decreased in all of the tissues of rats given goldenberry extract, while significant decreases were determined in the levels of vitamins K-1, K-2, D-2 and D-3 in all of tissues (except serum), and there were also decreases in the level of α-tocopherol and cholesterol in tis- sues of muscle, liver and kidney. In this study, it was shown that the goldenberry decreased the destructive effects of type-I diabetes by decreasing the serum glucose and lipid peroxida- tion and increasing the level of glutathione. It is believed that the obtained results would be used in fol- low-up of diabetic patients and in early diagnosis of the disease in future.
AtıfScopus4İncele - MakaleYalnız künye2019Scopus SJRQ4THE TOXIC EFFECT OF CADMIUM ON HUMAN ERYTHROCYTES AND NAC'S PROTECTIVE ROLE
Sahilli, Yeliz Cakir
The toxic effects cadmium (Cd), which is a heavy metal, on human erythrocytes and protective effects of N-acetyl-L-cysteine (NAC) on lipid peroxidation and antioxidant enzymes were investigated. The effects of 1, 50, 150 mu M doses of cadmium and 1mM NAC on the level of malondialdehyde (MDA) in human erythrocytes and superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) enzyme activities were investigated. When the Cd was applied alone, it was found that MDA level increased in erythrocytes and SOD, CAT and GPx activities decreased. No statistically significant difference was observed when 1mM NAC administered erythrocytes were compared with the control cells. However, the beneficial effect was seen only in administration doses of Cd at the levels of I and 50 mu M and NAC was observed to have a protective effect. As a result, NAC partially reduced the toxic effect caused by Cd on erythrocytes but could not completely prevent it.
- MakaleYalnız künye2018Scopus SJRQ1Antioxidant biomarkers in Gammarus pulex to evaluate the efficiency of electrocoagulation process in landfill leachate treatment
Serdar, Osman; Yildirim, Nuran Cikcikoglu; Tatar, Sule; Yildirim, Numan; Ogedey, Aysenur
The discharge of landfill leachate into the environment without effective treatment poses a serious threat for the aquatic ecosystems. This present study was undertaken to evaluate whether electrocoagulation process is efficient for treatment landfill leachate (LL) or not by using antioxidant biomarkers in Gammarus pulex. Glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and catalase (CAT) activities and malondialdehyde (MDA) and glutathione (GSH) levels in G. pulex exposed to untreated, treated, and diluted rates 1/10 and 1/20 in both LL during 24 and 96 h were tested. Physiochemical characteristics of leachate (chemical oxygen demand, electrical conductivity, pH, phosphate, turbidity, NH3, Cl−, and color) were determined pre and post treatment. All physiochemical characteristics of LL decreased after treatment process. GSH-Px and CAT activities and GSH and MDA levels were increased in untreated groups when compared to control (p < 0.05). After treatment by electrocoagulation, MDA and GSH levels and CAT activities were returned to control values. In conclusion, the abilities of LL to stimulate oxidative stress in G. pulex have been proven. The results revealed that antioxidant parameters are useful biomarkers for determining the treatment efficiency of the electrocoagulation process.
AtıfScopus19WoS17OpenAlex23İncele - MakaleYalnız künye2018Scopus SJRQ2The using of Gammarus pulex as a biomonitor in ecological risk assessment of secondary effluent from municipal wastewater treatment plant in Tunceli, Turkey
Tatar, Sule; Cikcikoglu Yildirim, Nuran; Serdar, Osman; Yildirim, Numan; Ogedey, Aysenur
The objectives of this research are the assessment of secondary effluents (SEs) quality by evaluating chemical parameters and biomarkers. For this purpose, MDA and GSH levels were determined by spectrofotometer. SOD, CAT, and GPX activities were determined by using ELISA kit in the groups of control and the groups exposed to SE. The level of MDA and the activities of SOD in Gammarus pulex vary depending on the exposure time. GSH levels and GSH-PX activities increased in G. pulex exposed to the effluent compared to the control during 24 h and 96 h. CAT activities were in SE group were found lower than the control in G. pulex during 24 h and 96 h. Current experimental results show that SOD, CAT, GPX activities, and GSH and MDA levels in G. pulex are sensitive and appropriate responses for assess the effects of anthropogenic contaminants on the aquatic ecosystems, particularly effluent complex mixtures.
AtıfScopus19WoS19OpenAlex22İncele - MakaleAçık Erişim2018Scopus SJRQ3Determination of Lipid Peroxidation and Fatty Acid Compositions in the Caviars of Rainbow Trout and Carp
Gürel Inanlı, Ayşe; Emir Çoban, Özlem; Yılmaz, Ökkeş; Özpolat, Emine; Karaton Kuzgun, Nermin
In this study, roes obtained from carp (Cyprinus carpio carpio) that were caught in Keban Dam Lake (Turkey) and cultured rainbow trout (Oncorhynchus mykiss) were processed as caviar, and the products were stored at + 4 C°. Lipid peroxidation and the compositions of fatty acids of these products were assessed during production and storage period. The result of fatty analyses showed that palmitic acid (16:0), stearic acid (18:0), palmitoleic acid (16:1), oleic acid (18:1), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), which are all essential fatty acids, were determined in the caviars of the roes obtained from rainbow trout and carp. According to results of chemical analyses, there were no significant differences in thiobarbituric acid reactive substances (TBARs) between rainbow trout and carp caviars (p > 0.05), but malondialdehyde (MDA) levels were found to be statistically significant (p < 0.01). It can be concluded that caviars obtained from both rainbow trout and carp roes are rich in fatty acids and take a part in a balanced and healthy diet.
AtıfScopus3WoS1OpenAlex4İncele - MakaleYalnız künye2018Scopus SJRQ2Effect of the novel biodegradable copolymer and soil salinity on the growth of corn plant
Torğut, Gülben; Beker Akbulut, Gülcin
Biodegradable and biocompatible poly (1,2-epoxy-3-phenoxy propane)-co-(ε-caprolactone) poly(EPP-co-ε-CL) copolymers were synthesized by ring-opening polymerization method at four different ε-CL ratios. Copolymers were characterized using Fourier-transform infrared spectroscopy, proton nuclear magnetic resonance (1H-NMR), thermogravimetric analysis, and differential scanning calorimetry. To examine their possible applications in agriculture, germination test and growth analyses of corn plants were carried out. For this purpose, corn (Zea mays L. cv. “72 May 80”) was allowed to germinate under suitable conditions. Copolymers, 200 mM salt (NaCl) solution, and both copolymers and salt solution were applied to the plants and compared with the control groups. On the 21st day, all the plants were harvested and were stored at −80°C until analysis. Differences in growth parameters, lipid peroxidation degrees, pigment analysis, and total carbohydrate analysis were tested in order to put forward copolymer and NaCl sensitivity of the corn. Statistical analysis was carried out using the SPSS 17.0 software program and the results were compared with each other. These results showed that the copolymers both have a positive effect on the carbohydrate and malondialdehyde (MDA), a product of lipid peroxidation content as well as the chlorophyll content. Moreover, poly(EPP-co-ε-CL0.88) was more efficient than was the other copolymers in the improvement of the detrimental effects of salinity in increasing chlorophyll, carbohydrate, and MDA content, and growth of corn plants. As a result of the study, it was demonstrated that all of the investigated parameters were affected by the applications of salt and copolymers.
AtıfScopus2WoS2OpenAlex3İncele - MakaleAçık Erişim2017Scopus SJRQ2Antioxidant Response in Duckweed After Exposure to Secondary Effluent from Municipal Wastewater Treatment Plant, Elazığ, Turkey
Tatar, Sule Yuksel; Obek, Erdal; Cikcikoglu Yildirim, Nuran
The aim of this study is to evaluate the effects of the effluent of Elazig Municipality Wastewater Treatment Plant on the oxidative defense capacity of aquatic plants (Lemna minor L. and Lemna gibba L.). For this purpose, malondialdehyde (MDA), glutathione (GSH), oxidized glutathione (GSSG), vitamin A (retinol), vitamin E (α-tocopherol), and vitamin C (Ascorbic acid) levels were determined by the HPLC (high performance liquid chromatography) in the control groups and the groups adapting to reactors fed with discharge water. The depletion of vitamins (A, E, and C), decrease of GSH/GSSG ratio, and increase of MDA that reflect a precarious state of the cell in L. minor L. and L. gibba L. were observed after exposure to wastewater. It can be suggested that the selected biomarkers are useful in understanding the biochemical mechanisms of the secondary effluents from wastewater treatment plant in L. minor L. and L. gibba L. as early warning indicators.
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