Sürdürülebilir Kalkınma Amaçları

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• 3

Yazarlar

• Benzer, Fulya(6)
• Erisir, Mine(4)
• Gur, Seyfettin(3)
• Kandemir, Fatih Mehmet(3)
• Kaya, Emre(3)
• Ozer Kaya, Seyma(3)
• Sonmez, Mustafa(3)
• Turk, Gaffari(3)
• Basbug, O.(1)
• Benzer, F.(1)
• Erişir, Mine(1)
• Gül, Y.(1)
• Issi, M.(1)
• Kandemir, F. M.(1)
• Kocabaş, Mehmet(1)
• Kutluyer, Filiz(1)
• Ozbey, Ulku(1)
• Savucu, Yuksel(1)
• Seyran, Ayse(1)
• Yildirim, Nuran Cikcikoglu(1)
• Özdemir, N.(1)
• Özçelik, Mehtap(1)

• MakaleAçık Erişim2020Scopus SJRQ2/r/munzur/3572
  Influence of vitamin E and vitamin E-selenium combination on arginase activity, nitric oxide level and some spermatological properties in ram semen

  Ozer Kaya, Seyma; Gur, Seyfettin; Erisir, Mine; Kandemir, Fatih Mehmet; Benzer, Fulya; Kaya, Emre; Turk, Gaffari; Sonmez, Mustafa

  The effects of vitamin E and vitamin E-selenium combination on seminal plasma arginase activity and nitric oxide level and some spermatological properties in rams were investigated in this study. For control group, animals were injected intramuscularly with physiological saline. For vitamin E group, rams were injected intramuscularly with 300 mg/ram vitamin E. For vitamin E + selenium group, animals were injected intramuscularly with 5 ml/ram vitamin E + selenium. The semen was collected by artificial vagina at 1st, 4th, 24th, 48th and 72nd hr after administration in each group. Significant decreases in seminal plasma arginase activity (at 1st, 24th and 48th hr), nitric oxide level (at 72nd hr) and abnormal sperm rate (at 1st, 24th and 72nd hr), and significant increases in semen volume (at 24th hr), semen mass activity (at 24th and 48th hr), sperm motility (at 24th, 48th and 72nd hr) and concentration (at 1st hr) were observed in vitamin E group compared with control group. Similarly, significant increase in semen volume (at 1st, 24th and 48th hr), mass activity, (at 48th hr), motility (at 48th and 72nd hr) and concentration (at 4th, 24th and 48th hr), and significant decrements in abnormal sperm rate (at 1st, 24th, 48th and 72nd hr), seminal plasma nitric oxide level (at 1st, 4th, 24th and 48th hr) and semen pH (at 24th and 48th hr) were detected in vitamin E + selenium group in comparison to the control group. As a result, it is suggested that vitamin E and/or vitamin E + selenium applications may improve reproductive performance.

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  AtıfScopus19·WoS16·OpenAlex19

  İncele
• MakaleAçık Erişim2020Scopus SJRQ2/r/munzur/3336
  The changes in semen quality, arginase activity and nitric oxide level in dexamethasone-treated rams

  Ozer Kaya, Seyma; Erisir, Mine; Gur, Seyfettin; Kandemir, Fatih Mehmet; Benzer, Fulya; Kaya, Emre; Sonmez, Mustafa; Turk, Gaffari

  This study was made to investigate the effects of intramuscular administrations of dexamethasone on seminal plasma nitric oxide levels and arginase activity, and some spermatological parameters in rams. Ten Akkaraman rams weighing 50–60 kg and 2 years old were used as material in this study. The study was performed during the breeding season (September–November) for rams. The semen was collected by artificial vagina at 1st, 4th, 24th, 48th, 72nd and 96th hours for control group before dexamethasone administration. For treatment group, 0.25 mg/kg dexamethasone was administered and semen was collected at the time points described for control group. Spermatological characteristics of semen samples (semen volume, pH, sperm motility, density and abnormal sperm rate), seminal plasma arginase enzyme activities and nitric oxide levels were determined. It was determined that the administration of dexamethasone was detected to decrease seminal plasma arginase activity (p <.05 and.01) and nitric oxide level (p <.05), semen volume (p <.05 and.01), mass activity (p <.05 and.01), sperm density (p <.05) and sperm motility (p <.05 and.01), and to increase abnormal sperm rate (p <.05 and.01). In conclusion, dexamethasone is not recommended to be used during the breeding season as it damages the sperm quality of the rams.

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  AtıfScopus10·WoS7·OpenAlex8

  İncele
• MakaleAçık Erişim2020Scopus SJRQ2/r/munzur/3200
  Evaluation of the role of L-arginine on spermatological parameters, seminal plasma nitric oxide levels and arginase enzyme activities in rams

  Ozer Kaya, Seyma; Kandemir, Fatih Mehmet; Gur, Seyfettin; Erisir, Mine; Benzer, Fulya; Kaya, Emre; Turk, Gaffari; Sonmez, Mustafa

  The purpose of this study is to investigate the effects of L-arginine on spermatological parameters, seminal plasma nitric oxide levels and arginase enzyme activities. Fertile rams that are 2–3 years old and weighing 50–60 kg were used as material. The semen was collected by artificial vagina at 1st, 4th, 24th, 48th, 72nd, 96th and 120th hours for the control group before L-arginine administration. For treatment groups, L-arginine was administered intraperitoneally at a dose of 5 mg kg−1 bw−1 and semen was collected at the time point described for the control group. Spermatological characteristics of semen samples (semen volume, pH, sperm motility, concentration and abnormal sperm rate), seminal plasma nitric oxide levels and arginase enzyme activities were determined. Increased seminal plasma nitric oxide level (p <.01), seminal plasma arginase activity (p <.01), semen volume (p <.05), semen mass activity (p <.05), sperm motility (p <.05) and concentration (p <.01) and decreased abnormal sperm rate (p <.05 and p <.01) were observed by L-arginine administration. In conclusion, it may be concluded that L-arginine application in rams during the breeding season may have positive effects on rams' reproductive performance.

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  AtıfScopus14·WoS10·OpenAlex11

  İncele
• MakaleAçık Erişim2019Scopus SJRQ2/r/munzur/3150
  l-Arginine Improves Sperm Motility in Threatened Coruh Trout Salmo coruhensis (Teleostei: Salmonidae)

  Kocabaş, Mehmet; Kutluyer, Filiz; Erişir, Mine; Benzer, Fulya

  l-arginine is a versatile amino acid and precursor of nitric oxide that provides protection for preventing free radical damage. Herein, experiments were designed to clarify the effect of l-arginine supplementation on the sperm motility of a threatened trout, Coruh trout Salmo coruhensis. Activation solution was supplemented with levels of 0 mM (Control), 2 mM, 4 mM, and 8 mM l-arginine, and motility and survival of sperm cells were assessed. The selected concentrations were determined according to results of our preliminary experiments. The sperm motility rates at l-arginine concentrations of 0, 2, 4, and 8 mM were 73.33 ± 5.77%, 76.67 ± 5.75%, 80.01 ± 0.01%, and 90.00 ± 0.05%, respectively; notility durations were 21.67 ± 2.08, 32.33 ± 3.79, 32.67 ± 1.15, and 37.00 ± 6.38 s, respectively. Significant effect of l-arginine supplementation was determined on the percentage and duration of motile spermatozoa (p < 0.05). The maximum increment was evoked at the greatest concentration (8 mM). Here, we showed that l-arginine supplement can improve sperm motility of S. coruhensis.

  AtıfScopus1·WoS1·OpenAlex2

  İncele
• MakaleAçık Erişim2016Scopus SJRQ3/r/munzur/4315
  The Effects of Dietary Antioxidants on the Arginase Activity and Nitric Oxide Level of Narrow-Clawed Turkish Crayfish (Astacus leptodactylus, Esch 1823) in Moulting Period

  Benzer, Fulya; Özçelik, Mehtap; Yildirim, Nuran Cikcikoglu

  The effects of dietary antioxidants (vitamine E, vitamine C, Astaxhantin, beta carotene) on arginase activity and nitric oxide levels of hepatopancreas and muscle of freshwater crayfish (Actacus leptodactylus) were investigated during moulting. 150 mg kg(-1) vitamine E (VE), 200 mg kg(-1) vitamine C (VC), 200 mg kg(-1) Astaxhantin and 200 mg kg(-1) beta carotene were added to experimental diets. A. leptodactylus with these diets were fed with 2% of their total weight daily, in a day during 75 days. Arginase activity was increased in muscle of crayfish fed the diets VC, VE, astaxanthin and beta karoten but in hepatopancreas arginase activity was increased with beta carotene when compared to control. NO levels in muscle were decreased when compared to control but this decrease was not statically significant. NO levels in hepatopancreas of crayfish fed the diets VC and astaxanthin were higher than control groups. Our results demonstrated that dietary antioxidants affect the arginase activity and nitric oxide level of freshwater crayfish (Astacus leptodactylus, Esch. 1823) during moulting.

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  AtıfWoS3·OpenAlex3

  İncele
• MakaleAçık Erişim2012Scopus SJRQ2/r/munzur/4225
  Changes in nitric oxide levels and erythrocyte arginase activities in patient with Down syndrome

  Ozbey, Ulku; Seyran, Ayse; Erisir, Mine; Benzer, Fulya; Savucu, Yuksel

  Down syndrome is a chromosome abnormality with specific clinical symptoms and mental retardation caused by trisomy of chromosome 21. There is evidence that oxygen free radicals play an important role in the pathophysiology of many neuropsychiatric disorders. Although, it has not been investigated yet, several recent studies proposed that nitric oxide related to oxidative stress and arginase may have a pathophysiological role in mental retardation. The purpose of this study was to determine plasma nitric oxide levels and erythrocyte arginase activities in patients with Down syndrome and in healthy children. Plasma nitric oxide levels and erythrocyte arginase activity were measured in 20 patients with Down syndrome (median age: 15.6 +/- 7.5) and 20 age-matched healthy subjects (median age: 16.2 +/- 7.4). Significant differences were found between erythrocyte arginase activity of the patients with Down syndrome (35.2 +/- 2.7 U/g hemoglobin (Hb)) and those of healthy children (43.5 +/- 2.9 U/g Hb), (P < 0.05). But we have not found any statistical difference between persons with Down syndrome and control group for nitric oxide (P > 0.05). It was concluded that the level of erythrocyte arginase activity could be considered as a useful marker for assessing the level of mental retardation in children with Down syndrome.

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  İncele
• MakaleYalnız künye2011Scopus SJRQ3/r/munzur/4265
  Plasma nitric oxide concentrations and erythrocyte arginase activities in lambs with contagious ecthyma

  Kandemir, F. M.; Issi, M.; Benzer, F.; Gül, Y.; Basbug, O.; Özdemir, N.

  The aim of the present study was to investigate the plasma nitric oxide concentrations and the erythrocyte arginase activities in lambs with contagious ecthyma, which frequently occurs in lambs and goat kids. The study was conducted on 10 Akkaraman, 1-2 month old lambs with contagious ecthyma (the clinical diagnosis was based on the presence of typical cauliflower-like proliferative lesions in lips, commissum labials, nostrils and udders) and on 10 apparently healthy lambs (controls) from the same flock. Plasma NO concentrations and erythrocyte arginase activities were determined on all animals using the Griess method and the thiosemicarbazide diacetylmonoxime urea (TDMU) method, respectively. Compared to the control group, the mean plasma NO concentration was significantly increased in the diseased group while the mean arginase activity was markedly depressed. Abnormally high NO concentrations and low enzyme activities were observed in 9 and 10 diseased lambs, respectively. Additionally, a negative correlation was evidenced between the 2 biochemical parameters. These results show that this viral infection is associated with some perturbations in the arginine metabolism, leading preferentially to the synthesis of NO, which is presumed to exhibit some antiviral properties.

  AtıfWoS7

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